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Results for "
nas-181
" in TargetMol Product Catalog- Inhibitors & Agonists4
NAS-181 free base
T69959205242-61-1
NAS-181 free base is a 5-HT(1B) receptor antagonist.
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Tofacitinib maleate
T699582052885-67-1
Tofacitinib maleate, also known as tasocitinib, CP-690550, is a Janus kinase (JAK) inhibitor. Tofacitinib maleate modulates the signaling pathway at the point of JAKs, preventing the phosphorylation and activation of STATs. JAK enzymes transmit cytokine signaling through pairing of JAKs (e.g., JAK1 JAK3, JAK1 JAK2, JAK1 TyK2, JAK2 JAK2). Tofacitinib maleate inhibited the in vitro activities of JAK1 JAK2, JAK1 JAK3, and JAK2 JAK2 combinations with IC50 of 406, 56, and 1377 nM, respectively.
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