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Search Result

Search Results for " leukemias "

Targets

Bcr-Abl Src Autophagy

13

Compounds

43

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6311 Bafetinib NS-187,INNO-406 Bcr-Abl , Src , Autophagy
Bafetinib (INNO-406) (INNO-406) is an effective and specific dual Bcr-Abl/Lyn inhibitor (IC50: 5.8/19 nM), and no inhibition of the phosphorylation of the T315I mutant and less effective to c-Kit and PDGFR.
T21503 (E/Z)-Zotiraciclib (E/Z)-TG02,(E/Z)-SB1317 FLT , JAK , CDK
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.
T0707L Cyclophosphamide DNA Alkylator/Crosslinker , DNA , MRP
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T3099 Pinometostat EPZ-5676 Histone Methyltransferase
Pinometostat (EPZ-5676) has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
T3078 SGI-1776 SGI-1776 free base,Pim-Kinase Inhibitor IX Apoptosis , FLT , Pim , Autophagy
SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
T12943 SNDX-5613 Epigenetic Reader Domain , Histone Methyltransferase
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
T26754 BC-23 NSC 45382,BC 23,BC23,NSC-45382,NSC45382 Proteasome
BC-23 (NSC 45382) is a potent proteasome inhibitor with antitumor and antimicrobial activity.BC-23 inhibits the CT-L activity of the proteasome and is used in the study of leukemias, lymphomas, gliomas, breast cancer, an...
T77339 BRD4-IN-4 Epigenetic Reader Domain
BRD4-IN-4 is a selective BRD4 inhibitor with an IC50 value of 6.83 μM for BRD4.BRD4-IN-4 selectively inhibits the proliferation of the MV4-11 cell line and arrests the cells in G1 phase.BRD4-IN-4 can be used to study MLL...
T70563 KC-11404
KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.
T74096 Prednimustine
Prednimustine (Leo 1031;NSC 134087) is the ester formed from Prednisolone and Chlorambucil . Prednimustine can be used for leukemias and lymphomas research [1] .
T69130 Zorubicin Rubidazon ; Rubidazone,Rubidazone,Rubidazon
Zorubicin (Rubidazon), a Daunorubicin derivative, inhibits DNA polymerases and interacts with topoisomerase II. It is utilized in the research of acute leukemias and sarcomas [1] [2] [3] [4] [5].
T33737 NSC 109555 NSC-109555,DDUG dimethanesulfonate,NSC109555,DDUG diMS
NSC 109555 is a selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 μM). Inhibits histone H1 phosphorylation (IC50 = 0.24 μM...
T68502 Dibrospidium Free Base
Dibrospidium Free Base is a dispirotripiperazine derivative and alkylating agent with potential antineoplastic and anti-inflammatory activities. The duration of DNA synthesis inhibition in tumor cells was found to correl...

Recombinant Proteins

Species：
Human (28)
Mouse (6)
Cynomolgus (4)
Rat (2)
Canine (1)
Human (1)
Rhesus (1)
Expression System：
HEK293 (27)
E. coli (14)
Baculovirus-Insect Cells (2)
Tag：
His (19)
hFc (10)
His,AVI (5)
C-His-Avi (3)
N-6His (2)
GST (1)
N-10His-Flag (1)
Tag Free (1)
hFc,AVI (1)
Cat No. Product Name Species Expression System
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His) Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-04116 KRAS Protein,Human,Recombinant(G12C & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01888 KRAS Protein,Human, Recombinant (Q61H, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06056 KRAS Protein, Human, Recombinant (G12D, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01103 CD25/IL2R alpha Protein, Human, Recombinant (His) Human HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05584 CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05090 CD25/IL2R alpha Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03644 CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03776 CD25/IL2R alpha Protein, Cynomolgus, Recombinant Cynomolgus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-01923 CD25/IL2R alpha Protein, Mouse, Recombinant (His) Mouse HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05644 CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated Rhesus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPK-00183 CD20 Protein, Human, Recombinant (His & Avi) Human E. coli
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until matur...
TMPK-00184 CD20 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until matur...
TMPK-00242 IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 sub...
TMPY-00708 CD34 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-01652 CD34 Protein, Mouse, Recombinant (His) Mouse HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05582 CD34 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05772 CD34 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06764 CD34 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-00709 CD34 Protein, Human, Recombinant (His) Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-03031 CD34 Protein, Rat, Recombinant (hFc) Rat HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06716 CD34 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06744 IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-00592 IL-3R alpha/CD123 Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-05418 IL-3R alpha/CD123 Protein, Human, Recombinant (hFc) Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-04034 IL-3R alpha/CD123 Protein, Canine, Recombinant (His) Canine HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-06793 IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-00076 IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-06715 IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPJ-00694 BRD4 Protein, Human, Recombinant (His & Flag) Human E. coli
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remain...
TMPY-02885 CD1B Protein, Human, Recombinant (hFc) Human HEK293
CD1B contains 1 Ig-like (immunoglobulin-like) domain and belongs to the CD1 family. CD1 family members are transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) protein...
TMPY-01401 Cyclin A1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Cyclin A1 is a member of the highly conserved cyclin family that is characterized by a dramatic periodicity in protein abundance, and belongs to the A-type cyclin subfamily. The mammalian A-type cyclin family consists of...
TMPU-00001 KRAS Protein, Human, Recombinant (G12S, GST) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau...
TMPY-01925 Nucleophosmin Protein, Human, Recombinant (His) Human E. coli
Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly an...
TMPJ-00510 KRAS Protein, Human, Recombinant (G12C, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau...
TMPY-04259 Nucleophosmin Protein, Human, Recombinant (aa 2-294, His) Human E. coli
Nucleophosmin 1 (NPM1), also known as nucleolar phosphoprotein B23 or numatrin, is a member of the nucleoplasmin family. Nucleophosmin (NPM) is a nucleolar phosphoprotein that plays multiple roles in ribosome assembly an...
TMPJ-00511 KRAS Protein, Human, Recombinant (G12V, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. As other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes becau...
TMPY-06345 KRAS Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-06138 KRAS Protein, Human, Recombinant (61Q, His) Human E. coli
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-05541 CD25/IL2R alpha Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-00858 CD25/IL2R alpha Protein, Human, Recombinant (hFc) Human HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03740 CD25/IL2R alpha Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
TMPY-01410
Species: Human
Expression System: HEK293
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
TMPY-04116
Species: Human
Expression System: E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
TMPY-04113
Species: Human
Expression System: E. coli
KRAS Protein,Human, Recombinant (Q61H, His)
TMPY-01888
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12D, His)
TMPY-06056
Species: Human
Expression System: E. coli
CD25/IL2R alpha Protein, Human, Recombinant (His)
TMPY-01103
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05584
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Rat, Recombinant (His)
TMPY-05090
Species: Rat
Expression System: Baculovirus-Insect Cells
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)
TMPY-03644
Species: Cynomolgus
Expression System: HEK293
CD25/IL2R alpha Protein, Cynomolgus, Recombinant
TMPY-03776
Species: Cynomolgus
Expression System: HEK293
CD25/IL2R alpha Protein, Mouse, Recombinant (His)
TMPY-01923
Species: Mouse
Expression System: HEK293
CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated
TMPY-05644
Species: Rhesus
Expression System: HEK293
CD20 Protein, Human, Recombinant (His & Avi)
TMPK-00183
Species: Human
Expression System: E. coli
CD20 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00184
Species: Human
Expression System: E. coli
IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated
TMPK-00242
Species: Human
Expression System: HEK293
CD34 Protein, Human, Recombinant (hFc)
TMPY-00708
Species: Human
Expression System: HEK293
CD34 Protein, Mouse, Recombinant (His)
TMPY-01652
Species: Mouse
Expression System: HEK293
CD34 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05582
Species: Human
Expression System: HEK293
CD34 Protein, Human, Recombinant (His), Biotinylated
TMPY-05772
Species: Human
Expression System: HEK293
CD34 Protein, Mouse, Recombinant (hFc)
TMPY-06764
Species: Mouse
Expression System: HEK293
CD34 Protein, Human, Recombinant (His)
TMPY-00709
Species: Human
Expression System: HEK293
CD34 Protein, Rat, Recombinant (hFc)
TMPY-03031
Species: Rat
Expression System: HEK293
CD34 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06716
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06744
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Mouse, Recombinant (His)
TMPY-00592
Species: Mouse
Expression System: HEK293
IL-3R alpha/CD123 Protein, Human, Recombinant (hFc)
TMPY-05418
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Canine, Recombinant (His)
TMPY-04034
Species: Canine
Expression System: HEK293
IL-3R alpha/CD123 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06793
Species: Human
Expression System: HEK293
IL-3R alpha/CD123 Protein, Mouse, Recombinant (hFc)
TMPY-00076
Species: Mouse
Expression System: HEK293
IL-3R alpha/CD123 Protein, Cynomolgus, Recombinant (His)
TMPY-06715
Species: Cynomolgus
Expression System: HEK293
BRD4 Protein, Human, Recombinant (His & Flag)
TMPJ-00694
Species: Human
Expression System: E. coli
CD1B Protein, Human, Recombinant (hFc)
TMPY-02885
Species: Human
Expression System: HEK293
Cyclin A1 Protein, Human, Recombinant (His)
TMPY-01401
Species: Human
Expression System: Baculovirus-Insect Cells
KRAS Protein, Human, Recombinant (G12S, GST)
TMPU-00001
Species: Human
Expression System: E. coli
Nucleophosmin Protein, Human, Recombinant (His)
TMPY-01925
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12C, His)
TMPJ-00510
Species: Human
Expression System: E. coli
Nucleophosmin Protein, Human, Recombinant (aa 2-294, His)
TMPY-04259
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (G12V, His)
TMPJ-00511
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06345
Species: Human
Expression System: E. coli
KRAS Protein, Human, Recombinant (61Q, His)
TMPY-06138
Species: Human
Expression System: E. coli
CD25/IL2R alpha Protein, Mouse, Recombinant (hFc)
TMPY-05541
Species: Mouse
Expression System: HEK293
CD25/IL2R alpha Protein, Human, Recombinant (hFc)
TMPY-00858
Species: Human
Expression System: HEK293
CD25/IL2R alpha Protein, Cynomolgus, Recombinant (hFc)
TMPY-03740
Species: Cynomolgus
Expression System: HEK293
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