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(4)
By Target- STING
- Apoptosis(2)
- S1P Receptor(2)
- NF-κB(1)
- Protease-activated Receptor(1)
- p38 MAPK(1)
- Others(3)
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Results for "
k145
" in TargetMol Product Catalog- Inhibitors & Agonists7
K145
T117391309444-75-4
K145 is inactive against SphK1 and other protein kinases. K145 induces cell apoptosis and has potently antitumor activity. K145 is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM.
- $1,670
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K145 hydrochloride
Cited
TQ01381449240-68-9In house
K145 hydrochloride is a selective sphk2 inhibitor with substrate competitiveness and oral activity, with IC50 of 4.3 µM and Ki of 6.4 µM. K145 hydrochloride can induce apoptosis and has strong antitumor activity.
- $50
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CitedUlevostinag (isomer 2)
MK-1454 (isomer 2)
T2087292082743-99-3
Ulevostinag isomer 2 (MK-1454 isomer 2) is an isomer of Ulevostinag, which acts as a STING agonist.
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Ulevostinag (isomer 3)
MK-1454 (isomer 3)
T2087302082743-98-2
Ulevostinag (isomer 3) (example 246) is an effective stimulator of the STING (stimulator of interferon genes) pathway. It plays a significant role in anti-tumor research.
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Ulevostinag (isomer 4)
MK-1454 (isomer 4)
T2087312082743-97-1
Ulevostinag isomer 4 (MK-1454 isomer 4) is an isomer of Ulevostinag, which functions as a STING agonist.
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K-14585
T27708880546-17-8
K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8.
- $4,368
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Ulevostinag
Ulevostinag, MK-1454
T394892082743-96-0
Ulevostinag (MK-1454) is a STING agonist.
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