Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 152.00 | |
5 mg | In stock | $ 373.00 | |
10 mg | In stock | $ 473.00 | |
25 mg | In stock | $ 777.00 | |
50 mg | In stock | $ 1,090.00 | |
100 mg | In stock | $ 1,460.00 | |
500 mg | In stock | $ 2,930.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 397.00 |
Description | TBOPP is a selective DOCK1 inhibitor (IC50 : 8.4 μM), with anti-tumor activity for broader types of tumors. |
Targets&IC50 | DOCK1:8.4 μM , DOCK1 DHR-2 domain:7.1 μM (kd) |
In vitro | TBOPP as a selective inhibitor of DOCK1. TBOPP dampened DOCK1-mediated invasion, macropinocytosis, and survival under the condition of glutamine deprivation without impairing the biological functions of the closely related DOCK2 and DOCK5 proteins. |
In vivo | TBOPP treatment suppressed cancer metastasis and growth in vivo in mice. |
Molecular Weight | 490.49 |
Formula | C24H21F3N2O4S |
CAS No. | 1996629-79-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 120 mg/mL (244.65 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TBOPP 1996629-79-8 Others Inhibitor inhibit inhibitor