Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 115.00 | |
5 mg | In stock | $ 247.00 | |
10 mg | In stock | $ 397.00 | |
25 mg | In stock | $ 663.00 | |
50 mg | In stock | $ 945.00 | |
100 mg | In stock | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 287.00 |
Description | CDK4/6-IN-6 is a potent CDK4/CDK6 inhibitor with Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively. |
Targets&IC50 | CDK6-CyclinD3:13.9 nM (Ki), CDK4-CyclinD1:0.6 nM (Ki) |
In vitro | CDK4/6-IN-6 (example A94) has IC 50 s of 38.5 nM and 144.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3 using phospho-Rb S795 ELISA assays in JEKO-1 and MV4-1 1 cells[1]. |
Molecular Weight | 463.93 |
Formula | C22H27ClFN5O3 |
CAS No. | 2380321-51-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (118.55 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CDK4/6-IN-6 2380321-51-5 Cell Cycle/Checkpoint CDK CDK-4/6-IN-6 Inhibitor inhibit Cyclin Cyclin dependent kinase CDK4/6 IN 6 CDK4/6IN6 inhibitor