T77939 |
WBC100
|
2095780-08-6
|
98%
|
|
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway,...
|
T78055 |
MYC-RIBOTAC
|
|
98%
|
|
MYC-RIBOTAC, a ribonuclease-targeting chimera (RIBOTAC) specific to the MYC internal ribosome entry site (IRES), comprises an MYC mRNA-binding element tethered t...
|
T78986 |
MDEG-541
|
|
98%
|
|
MDEG-541 is a potent MYC-MAX degrader that exhibits antiproliferative activity by downregulating the expression of GSPT1, MYC, GSPT2, and PLK1 proteins [1].
|
T79438 |
C-Myc inhibitor 11
|
|
98%
|
|
c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat ph...
|
T79439 |
C-Myc inhibitor 12
|
|
98%
|
|
Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].
|
T79872 |
M-Se3
|
2829939-44-6
|
98%
|
|
m-Se3 is a potent, selective inhibitor of c-MYC transcription with demonstrated capability to inhibit tumor growth and exhibit anti-cancer activity [1].
|
T40419 |
IRES-C11
|
342416-30-2
|
98%
|
|
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction ...
|
TN3708 |
Coronarin D
|
119188-37-3
|
98%
|
|
Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration...
|
TN2177 |
Sanggenol L
|
329319-20-2
|
98%
|
|
Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than against normal human gingival fibroblasts (HGF), it induces apopto...
|
TN4582 |
Moracin T
|
1146113-27-0
|
98%
|
|
Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, inc...
|
T16839 |
SAJM589
|
2089-82-9
|
98%
|
|
sAJM589 is a Myc inhibitor(IC50: 1.8 μM).
|
T11783 |
KSI-3716
|
1151813-61-4
|
98%
|
|
KSI-3716 is an inhibitor of c-Myc.
|
TN1354 |
Aaptamine
|
85547-22-4
|
98%
|
|
Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.
|
T10702 |
CBP/p300-IN-2
|
2158265-96-2
|
98%
|
|
CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc) extracted from patent WO2017205538A1 (example 25).
|
TN4581 |
Moracin D
|
69120-07-6
|
98%
|
|
Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization o...
|
T60019 |
VPC-70063
|
13571-44-3
|
99.93%
|
|
VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inh...
|
T0617 |
Nicotinamide N-oxide
|
1986-81-8
|
99.9%
|
|
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD...
|
T3048 |
10058-F4
|
403811-55-2
|
99.82%
|
|
10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target g...
|
T9093 |
NY2267
|
886053-73-2
|
99.6%
|
|
NY2267 (Acetic acid, 2-[[6-[2-(cyclohexylamino)-1-[[(4-methoxyphenyl)methyl](2-pyridinylcarbonyl)amino]-2-oxoethyl]-2-naphthalenyl]oxy]-, 1,1-dimethylethyl ester...
|
T4367 |
Mycro 3
|
944547-46-0
|
99.51%
|
|
Mycro 3 is potent and selective for c-Myc in whole cell assays.
|