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GNRH Receptor

The gonadotropin-releasing hormone receptor (GnRHR), also known as the luteinizing hormone releasing hormone receptor (LHRHR), is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is the receptor of gonadotropin-releasing hormone (GnRH). The GnRHR is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T80116 LHRH 35263-73-1 98%
LHRH
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applicat...
T80422 Phoenixin-14 1415039-79-0 98%
Phoenixin-14
Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfu...
T10988 Degarelix 214766-78-6 98%
Degarelix
Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
T72492 GnRH-R antagonist 1 2826273-90-7 98%
GnRH-R antagonist 1
GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic ef...
T21309 Nafarelin acetate(76932-56-4 free base) 76932-60-0 99.98%
Nafarelin acetate(76932-56-4 free base)
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decreas...
T5031 Elagolix sodium 832720-36-2 99.93%
Elagolix sodium
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
TP2107L Histrelin acetate 220810-26-4 99.91%
Histrelin acetate
Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It acts on particular cells of the pituitary gland called ...
T21410 Triptorelin acetate(57773-63-4 free base) 140194-24-7 99.90%
Triptorelin acetate(57773-63-4 free base)
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and ...
TP2323L Deslorelin acetate(57773-65-6 free base) 99.84%
Deslorelin acetate(57773-65-6 free base)
Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist)
T1494 Alarelin Acetate 79561-22-1 99.81%
Alarelin Acetate
Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.
T27837 Linzagolix 935283-04-8 99.68%
Linzagolix
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharm...
T3630 Relugolix 737789-87-6 99.67%
Relugolix
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with po...
TP1700L LGnRH-III, lamprey acetate(147859-97-0 free base) 99.66%
LGnRH-III, lamprey acetate(147859-97-0 free base)
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of...
T25742 Linzagolix choline 1321816-57-2 99.64%
Linzagolix choline
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibr...
TP1307 Buserelin Acetate (57982-77-1 free base) 68630-75-1 99.23%
Buserelin Acetate (57982-77-1 free base)
Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
T22025 AG 045572 263847-55-8 98.99%
AG 045572
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is ...
T10988L Degarelix acetate(214766-78-6 free base) 98.66%
Degarelix acetate(214766-78-6 free base)
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
T5520L Cetrorelix diacetate 130143-01-0 98.38%
Cetrorelix diacetate
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppres...
TP1434L Lecirelin acetate(61012-19-9 free base) 98.1%
Lecirelin acetate(61012-19-9 free base)
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts....
T17301 Opigolix 912587-25-8 98.07%
Opigolix
Opigolix (ASP-1707) is an orally available gonadotropin-releasing hormone (GnRH) receptor antagonist for the study of endometriosis-related pain, rheumatoid arth...
LHRH
T80116
Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has applicat...
Phoenixin-14
T80422
Phoenixin-14 (PNX-14), an active endogenous isoform, induces an anxiolytic effect by activating the AHA GnRH system in mice and protects against ischemia/reperfu...
Degarelix
T10988
Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
GnRH-R antagonist 1
T72492
GnRH-R antagonist 1 (Compound 21a), is an orally active, membrane-permeable agent with a high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic ef...
Nafarelin acetate(76932-56-4 free base)
T21309
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decreas...
Elagolix sodium
T5031
Elagolix sodium (NBI-56418 sodium) is a GnRH receptor (GnRHR) antagonist ( IC50 and Ki of 0.25 and 3.7 nM, respectively).
Histrelin acetate
TP2107L
Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It acts on particular cells of the pituitary gland called ...
Triptorelin acetate(57773-63-4 free base)
T21410
Triptorelin acetate(57773-63-4 free base) (CL 118,532) is used as a GnRH agonist. It decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and ...
Deslorelin acetate(57773-65-6 free base)
TP2323L
Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist)
Alarelin Acetate
T1494
Alarelin Acetate is a synthetic GnRH agonist which can directly inhibit proliferation and DNA synthesis of rat GSMC through GnRH receptors.
Linzagolix
T27837
Linzagolix is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which is under development by Kissei Pharm...
Relugolix
T3630
Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with po...
LGnRH-III, lamprey acetate(147859-97-0 free base)
TP1700L
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of...
Linzagolix choline
T25742
Linzagolix choline is an orally available non-peptide gonadotropin-releasing hormone (GnRH) antagonist. It can be used to study pain associated with uterine fibr...
Buserelin Acetate (57982-77-1 free base)
TP1307
Buserelin Acetate (57982-77-1 free base) (Buserelin Acetate) is an agonist of gonadotropin-releasing hormone receptor(GnRHR).
AG 045572
T22025
AG 045572 is a potent GnRH receptor antagonist that inhibits the GnRH receptor in humans and rats with Ki values of 6.0 nM and 3.8 nM, respectively.AG 045572 is ...
Degarelix acetate(214766-78-6 free base)
T10988L
Degarelix acetate is a competitive and reversible antagonist of gonadotropin-releasing hormone receptor (GnRHR) .
Cetrorelix diacetate
T5520L
Cetrorelix diacetate (NS-75A) is is a gonadotropin-releasing hormone antagonist. It works by blocking the action of GnRH upon the pituitary, thus rapidly suppres...
Lecirelin acetate(61012-19-9 free base)
TP1434L
Lecirelin acetate is a synthetic GnRH (gonadotropin releasing hormone) analogue which shows a great efficacy in the treatment of bovine ovarian follicular cysts....
Opigolix
T17301
Opigolix (ASP-1707) is an orally available gonadotropin-releasing hormone (GnRH) receptor antagonist for the study of endometriosis-related pain, rheumatoid arth...
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TargetMol