CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-95 KDa and the accession number is P28908.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 110.00 | |
50 μg | 5 days | $ 310.00 | |
500 μg | 5 days | $ 1,570.00 | |
1 mg | 5 days | $ 2,230.00 |
Description | CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 60-95 KDa and the accession number is P28908. |
Species | Human |
Expression System | HEK293 Cells |
Tag | C-6xHis |
Accession Number | P28908 |
Synonyms | Lymphocyte activation antigen CD30, TNFRSF8, Tumor necrosis factor receptor superfamily member 8, Ki-1 antigen, CD30L receptor, CD30 |
Amino Acid | Phe19-Lys379 |
Construction | Phe19-Lys379 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 60-95 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 7.5. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CD30/TNFRSF8 Protein, Human, Recombinant (aa 19-379, His) Lymphocyte activation antigen CD30 CD 30 TNFRSF8 Tumor necrosis factor receptor superfamily member 8 TNFRSF-8 Ki-1 antigen TNFRSF 8 CD30L receptor CD-30 CD30 recombinant recombinant-proteins proteins protein