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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
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Anti-Cardiovascular Disease Compound Library

Catalog No. L5400
  Library Compound List   Excel SDF

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1408 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 1408 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (2.39 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L5400)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Autophagy (161)
VEGFR (154)
Apoptosis (147)
Calcium Channel (147)
Adrenergic Receptor (140)
COX (95)
Endogenous Metabolite (88)
Sodium Channel (82)
PDE (75)
PDGFR (57)
TNF (56)
5-HT Receptor (48)
TGF-beta/Smad (47)
RAAS (45)
Antibacterial (45)
AChR (43)
Potassium Channel (42)
Dopamine Receptor (40)
c-Kit (39)
FGFR (37)
FLT (37)
NF-κB (36)
IL Receptor (35)
PARP (29)
Reactive Oxygen Species (28)
CDK (26)
Histamine Receptor (25)
MMP (25)
Parasite (22)
PKC (21)
PPAR (21)
JAK (20)
ALK (19)
c-Met/HGFR (18)
IGF-1R (18)
Antibiotic (17)
EGFR (17)
p38 MAPK (16)
Carbonic Anhydrase (16)
c-RET (16)
Src (16)
ATPase (16)
Ferroptosis (16)
HIV Protease (15)
Thrombin (15)
Mitophagy (15)
P450 (15)
Adenosine Receptor (15)
Prostaglandin Receptor (15)
Antifungal (14)
Norepinephrine (14)
HMG-CoA Reductase (14)
Endothelin Receptor (13)
NO Synthase (13)
Influenza Virus (12)
ERK (12)
DNA/RNA Synthesis (12)
Akt (11)
Raf (11)
Rho (10)
Glucocorticoid Receptor (10)
Tyrosine Kinases (10)
Histone Acetyltransferase (10)
BACE (10)
P-gp (10)
Antioxidant (9)
AMPK (9)
Beta Amyloid (9)
GABA Receptor (9)
Drug Metabolite (9)
Serotonin Transporter (9)
Proton pump (8)
Aurora Kinase (8)
P2Y Receptor (8)
Interleukin (8)
STAT (8)
iGluR (8)
Bcr-Abl (8)
MEK (8)
Guanylate cyclase (8)
Beta-Secretase (8)
Topoisomerase (7)
CaMK (7)
NMDAR (7)
ROS (7)
ROCK (7)
Phospholipase (7)
TRP/TRPV Channel (7)
PI3K (7)
MRP (7)
PKA (7)
GSK-3 (7)
Ras (7)
TAM Receptor (7)
Virus Protease (7)
HIF/HIF Prolyl-Hydroxylase (7)
c-Fms (6)
Tyrosinase (6)
HDAC (6)
Dehydrogenase (6)
Caspase (6)
Acetyl-CoA Carboxylase (6)
Trk receptor (6)
IκB/IKK (6)
Nrf2 (6)
Factor Xa (6)
Opioid Receptor (5)
JNK (5)
HSV (5)
Syk (5)
NADPH (5)
Lipoxygenase (5)
Hydroxylase (5)
Wnt/beta-catenin (5)
HIF (5)
Nucleoside Antimetabolite/Analog (5)
SARS-CoV (4)
GPR (4)
Proteasome (4)
MAO (4)
Microtubule Associated (4)
Estrogen/progestogen Receptor (4)
FAK (4)
Chk (4)
NOD-like Receptor (NLR) (4)
p53 (4)
mTOR (4)
Monoamine Oxidase (4)
NOS (4)
GluR (4)
Chloride channel (4)
RSV (4)
Epigenetic Reader Domain (4)
CETP (4)
Tie-2 (4)
BCL (4)
Neprilysin (4)
Ephrin Receptor (4)
Serine Protease (4)
NOD (4)
Anti-infection (4)
Mitochondrial Metabolism (4)
PGE Synthase (3)
HER (3)
GST (3)
Imidazoline Receptor (3)
Reverse Transcriptase (3)
TLR (3)
MLK (3)
AChE (3)
SGLT (3)
Acyltransferase (3)
Ligand for E3 Ligase (3)
S6 Kinase (3)
PDK (3)
Casein Kinase (3)
Thyroid hormone receptor(THR) (3)
CSF-1R (3)
Leukotriene Receptor (3)
Arginase (3)
FXR (3)
Liver X Receptor (3)
Molecular Glues (3)
DPP-4 (3)
Fatty Acid Synthase (3)
DNA Alkylation (3)
P2X Receptor (3)
DNA Alkylator/Crosslinker (3)
Bradykinin Receptor (3)
ABC (3)
Serine/threonin kinase (3)
Glutathione Peroxidase (3)
Antifolate (3)
transporter (2)
Platelet aggregation (2)
Sirtuin (2)
Na-K-Cl cotransporter (2)
Estrogen Receptor/ERR (2)
Myosin (2)
IRE1 (2)
Gap Junction Protein (2)
PYK2 (2)
Histone Demethylase (2)
DNA Methyltransferase (2)
FLAP (2)
RIP kinase (2)
LDL (2)
NADPH-oxidase (2)
PAFR (2)
Na+/Ca2+ Exchanger (2)
HBV (2)
LTR (2)
LRRK2 (2)
CaSR (2)
SGK (2)
Epoxide Hydrolase (2)
Androgen Receptor (2)
DHFR (2)
Xanthine Oxidase (2)
CCR (2)
CFTR (2)
Lipid (2)
AhR (2)
HCV Protease (2)
MAPK (2)
Integrin (2)
Amino Acids and Derivatives (2)
Protease-activated Receptor (2)
Monoamine Transporter (2)
cAMP (2)
Antifection (2)
Progesterone Receptor (1)
Discoidin Domain Receptor (DDR) (1)
Phosphatase (1)
Neurokinin receptor (1)
Thrombopoietin Receptor (1)
TOPK (1)
Lipase (1)
Arrestin (1)
IRAK (1)
IFNAR (1)
Sigma receptor (1)
Ligands for Target Protein for PROTAC (1)
DprE1 (1)
Histone Methyltransferase (1)
DNA-PK (1)
ROR (1)
NPC1L1 (1)
Transferase (1)
Adenylyl cyclase (1)
Reductase (1)
Aryl Hydrocarbon Receptor (1)
N-Acetylglucosaminyltransferase (1)
Hedgehog/Smoothened (1)
Free radical scavengers (1)
BTK (1)
HSP (1)
Anion Exchanger (1)
Antiviral (1)
Isocitrate Dehydrogenase (IDH) (1)
HCN Channel (1)
FAAH (1)
GPCR19 (1)
BCRP (1)
ATP Citrate Lyase (1)
Vasopressin Receptor (1)
CXCR (1)
PAD (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
DNA (1)
ACK (1)
Aminopeptidase (1)
GlyT (1)
PLK (1)
IAP (1)
VDAC (1)
cell cycle arrest (1)
Cysteine Protease (1)
Glucokinase (1)
CRISPR/Cas9 (1)
Melanocortin Receptor (1)
Amylase (1)
Retinoid Receptor (1)
Decarboxylase (1)
Immunology/Inflammation related (1)
Adiponectin receptor (1)
UGT (1)
Gamma-secretase (1)
Pyroptosis (1)
PAI-1 (1)
DNA gyrase (1)
ASK (1)
PKM (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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