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Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as sex, age, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0877 Gallic acid 149-91-7 99.95%
Gallic acid
Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
T19418 Methionine sulfoxide 62697-73-8 99.95%
Methionine sulfoxide
Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in v...
T10038 11-cis-Vaccenyl acetate 6186-98-7 99.95%
11-cis-Vaccenyl acetate
11-cis-Vaccenyl acetate ((Z)-Octadec-11-enyl acetate) activates olfactory neurons located in the T1 sensilla on the antenna and mediates aggregation behavior in ...
T7437 3-(3-Hydroxyphenyl)propionic Acid 621-54-5 99.95%
3-(3-Hydroxyphenyl)propionic Acid
3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bo...
T4889 2,6-Diaminoheptanedioic acid 583-93-7 99.95%
2,6-Diaminoheptanedioic acid
Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into pe...
T4537 Cholic acid sodium 361-09-1 99.95%
Cholic acid sodium
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
T1614 Hydrocortisone 50-23-7 99.95%
Hydrocortisone
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolyt...
T6873 Lauric Acid 143-07-7 99.95%
Lauric Acid
Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone...
T4716 Pyrrole-2-carboxylic acid 634-97-9 99.95%
Pyrrole-2-carboxylic acid
Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline...
T2220 2-Methoxyestradiol 362-07-2 99.95%
2-Methoxyestradiol
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by red...
T6316 Calcitriol 32222-06-3 99.94%
Calcitriol
Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorpti...
T10024 1-Octanol 111-87-5 99.94%
1-Octanol
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for n...
T3758 2,6-Dimethoxybenzoic acid 1466-76-8 99.94%
2,6-Dimethoxybenzoic acid
2, 6-Dimethoxybenzoic acid is an active biochemical.
T2910 Flavonol 577-85-5 99.94%
Flavonol
Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, ...
T0760 Cholesterol 57-88-5 99.94%
Cholesterol
Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is w...
T3235 Rebaudioside A 58543-16-1 99.94%
Rebaudioside A
Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.
T0010 6-Mercaptopurine 50-44-2 99.94%
6-Mercaptopurine
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting puri...
T2829 Isoalantolactone 470-17-7 99.94%
Isoalantolactone
Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.
T36983 Cyclic-di-GMP disodium 2222132-40-1 99.93%
Cyclic-di-GMP disodium
Cyclic-di-GMP disodium (5GP-5GP disodium) is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm fo...
T3329 4',7-Dimethoxyisoflavone 1157-39-7 99.93%
4',7-Dimethoxyisoflavone
4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.
Gallic acid
T0877
Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
Methionine sulfoxide
T19418
Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in v...
11-cis-Vaccenyl acetate
T10038
11-cis-Vaccenyl acetate ((Z)-Octadec-11-enyl acetate) activates olfactory neurons located in the T1 sensilla on the antenna and mediates aggregation behavior in ...
3-(3-Hydroxyphenyl)propionic Acid
T7437
3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) is one of the major metabolites of ingested caffeic acid.it inhibited osteoclastogenesis and bo...
2,6-Diaminoheptanedioic acid
T4889
Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall. DAPA is incorporated or integrated into pe...
Cholic acid sodium
T4537
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity.
Hydrocortisone
T1614
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolyt...
Lauric Acid
T6873
Lauric Acid (Dodecylic acid),which is found naturally in various plant and animal fats and oils, is a saturated medium-chain fatty acid with a 12-carbon backbone...
Pyrrole-2-carboxylic acid
T4716
Pyrrole-2-carboxylic acid (Minaline) was first identified as a degradation product of sialic acids, then as a derivative of the oxidation of the D-hydroxyproline...
2-Methoxyestradiol
T2220
2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by red...
Calcitriol
T6316
Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorpti...
1-Octanol
T10024
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for n...
2,6-Dimethoxybenzoic acid
T3758
2, 6-Dimethoxybenzoic acid is an active biochemical.
Flavonol
T2910
Flavonol (3-Hydroxyflavone) is a member of the class of compounds known as flavonols. 3-hydroxyflavone can be found in a number of food items such as brassicas, ...
Cholesterol
T0760
Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is w...
Rebaudioside A
T3235
Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.
6-Mercaptopurine
T0010
6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting puri...
Isoalantolactone
T2829
Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.
Cyclic-di-GMP disodium
T36983
Cyclic-di-GMP disodium (5GP-5GP disodium) is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm fo...
4',7-Dimethoxyisoflavone
T3329
4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.
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TargetMol