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Cat No. | Product Name | Synonyms | Targets |
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T15179 | DTSSP Crosslinker | Others | |
DTSSP Crosslinker is a cleavable ADC linker and can be used to synthesize antibody-drug conjugates (ADCs). | |||
T15175 | DSP Crosslinker | Others | |
DSP Crosslinker is a cleavable ADC linker, used in antibody-drug conjugates (ADCs) synthesis[1]. | |||
T15176 | DSS Crosslinker | Others | |
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters a... | |||
T15171 | DSG Crosslinker | Others | |
DSG Crosslinker is a cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T14833L | BS3 Crosslinker disodium | Others | |
BS3 Crosslinker disodium is a non-cleavable ADC linker used in antibody-drug conjugates (ADCs) synthesis. | |||
T34746 | Sulfo-SANPAH Crosslinker | Sulfo-SANPAH Cross-linker,Sulfo-SANPAH Cross linker | Others |
Sulfo-SANPAH Crosslinker (Sulfo-SANPAH Cross linker) is a water-soluble isobisfunctional protein crosslinker. | |||
T15203 | EGNHS | EGS crosslinker | Others |
EGNHS (EGS crosslinker) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | |||
T19941 | MBS Crosslinker | MBS protein crosslinker | |
MBS crosslinker is a non-cleavable, water-insoluble, heterobifunctional protein crosslinking reagent. The MBS protein crosslinker extended spacer arm analog is SMPB crosslinker SATA Protein Modifier can be used to add su... | |||
T6741 | SPDP | SPDP Crosslinker | Others |
SPDP is a short-chain crosslinker, which is used for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. SPDP could ... | |||
T30599 | BS3-d4 Deuterated Crosslinker | Deuterated Crosslinker BS3-d4,BS3-d4,D4-BS3 | |
BS3-d4 Deuterated Crosslinker or Bis(Sulfosuccinimidyl) 2,2,7,7-suberate-d4, is a water-soluble and membrane impermeable protein crosslinking agent. | |||
T16880 | SIA Crosslinker | Others | |
SIA Crosslinker is a non-cleavable ADC linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T14833 | BS3 Crosslinker | Others | |
BS3 Crosslinker is a non-cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. It is utilized specifically for its proficiency in connecting antibodies with drugs, enhancing the overall effici... | |||
T16903 | SMPH Crosslinker | Others | |
SMPH Crosslinker is an alkyl/ether-based PROTAC linker utilized for synthesizing PROTACs[1]. | |||
T34742 | Sulfo-EGS Crosslinker | ||
Sulfo-egs crosslinker or ethylene glycol bis (sulfosuccinimide succinate) is a water-soluble isofunctional crosslinker that is not permeable to cell membranes and can be used to label cell surface proteins. | |||
T19947 | EDC hydrochloride | EDC-HCl Crosslinker,1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride | Others |
EDC hydrochloride (EDC-HCl Crosslinker) is a zero-length crosslinker. EDC hydrochloride is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals. | |||
T14832 | BS2G Crosslinker disodium | Others | |
BS2G Crosslinker (disodium) is a non-cleavable linker employed for synthesizing antibody-drug conjugates (ADCs)[1]. | |||
T19946 | DCC Crosslinker | DCC Cross-linker,Cyclohexaamine | |
DCC Crosslinker is a zero-length crosslinker. DCC crosslinker is commonly used in the synthesis of active ester-containing reagents. | |||
T18864 | UAA crosslinker 1 | Others | |
UAA crosslinker 1 hydrochloride is an Amber codon-activating agent utilized for the incorporation of non-canonical amino acids (ncAAs) into proteins. This incorporation is achieved in vivo by leveraging the promiscuous a... | |||
T30597 | BS2G Crosslinker | BS2G Cross linker,BS2G Cross-linker | |
BS2G crosslinker (Bis[Sulfosuccinimidyl] glutarate) is an amine reactive, water-soluble, isofunctional protein crosslinker. The molecule is impenetrable to cell membranes and can be used to label cell surface proteins. | |||
T31584 | DST Crosslinker | DST Cross linker,DST Cross-linker | |
DST crosslinker(disuccinimide tartarate) is an isotype bifunctional, cleavable crosslinker (cleavable by an oxidizer) for applications that require crosslinking cleavability and that do not interfere with protein disulfi... | |||
T19944 | DSSeb Crosslinker | DSSeb Cross linker,DSSeb Cross-linker | |
DSSeb Crosslinker is a homobifunctional cross-linking reagent. It is useful in protein crosslinking and making antibody-drug conjugates. | |||
T19943 | SMPB Crosslinker | SMPB Cross linker,SMPB Cross-linker | |
SMPB crosslinker is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker. SMPB crosslin... | |||
T19942 | SBA Crosslinker | SBA Cross-linker,SBA Cross linker | |
SBA crosslinker is a sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. SBA protein crosslinker is non-cleavable and is among the shortest amine and sulfhydryl reactive crosslinking reagents k... | |||
T31583 | DSS-d4 Deuterated Crosslinker | ||
DSS-d4 Deuterated Crosslinker, or Bis[Succinimidyl] 2,2,7,7-suberate-d4 is a membrane permeable crosslinker with four deuterium atoms. | |||
T31581 | DSG-d4 Deuterated Crosslinker | ||
DSG-d4 Deuterated Crosslinker, or Bis[Succinimidyl] 2,2,4,4-glutarate-d4 is a protein crosslinker that is permeable to cell membranes. | |||
T33904 | PDPH Crosslinker | PDPH Cross linker,SPDP Hydrazide,PDPH Cross-linker | |
PDPH crosslinker(SPDP Hydrazide) is a lytic heterobisfunctional protein crosslinker. | |||
T24842 | Sulfo-SIA Crosslinker | Sulfo-SIA Cross-linker,Sulfo-SIA Cross linker | |
Sulfo-SIA Crosslinker is a non-cleavable, heterobifunctional protein crosslinker. Sulfo-SIA Crosslinker is useful in making antibody-drug conjugates. | |||
T24841 | Sulfo-MBS Crosslinker | Sulfo-MBS Cross linker,Sulfo-MBS Cross-linker | |
Sulfo-MBS Crosslinker is a non-cleavable, water-soluble, heterobifunctional protein crosslinking reagent. It is commonly used to crosslink haptens to carrier proteins and enzymes to antibodies. | |||
T18863 | UAA crosslinker 1 hydrochloride | Others | |
UAA crosslinker 1 hydrochloride is an amber codon used to incorporate non-canonical amino acids (ncAAs) into proteins in vivo. This is achieved by leveraging the promiscuous activity of specific wildtype and engineered a... | |||
T30598 | BS2G-d4 Deuterated Crosslinker | D4-BS2G,BS2G-d4 | |
BS2G-d4 or Bis(Sulfosuccinimidyl) 2,2,4,4-glutarate-d4, is a water-soluble and membrane impermeable protein crosslinking agent. | |||
T74339 | DNA crosslinker 3 dihydrochloride | ||
DNA Crosslinker 3 (dihydrochloride) (Compound 1) is a potent minor groove binder, exhibiting a DNA binding affinity (ΔTm) of 1.4°C, and serves as a valuable tool in anticancer research [1]. | |||
T74337 | DNA crosslinker 1 dihydrochloride | ||
DNA Crosslinker 1 (dihydrochloride) serves as a potent binder for the DNA minor groove, exhibiting a DNA binding affinity (ΔTm) of 1.1°C. This compound is utilized in research focused on anticancer therapies [1]. | |||
T74340 | DNA crosslinker 4 dihydrochloride | ||
DNA Crosslinker 4 (dihydrochloride) is a potent binder of the DNA minor groove with inhibitory effects on cancer cell lines NCI-H460, A2780, and MCF-7. It is utilized in research for anticancer applications [1]. | |||
T74338 | DNA crosslinker 2 dihydrochloride | ||
DNA crosslinker 2 (dihydrochloride) is a potent minor groove binder exhibiting a Δ T m of 1.2 °C, indicative of its DNA binding affinity. This compound demonstrates inhibitory activity against cancer cell lines NCI-H460,... | |||
T18865 | Azide-phenylalanine hydrochloride | UAA crosslinker 2 | Others |
UAA crosslinker 2 is a phenylalanine derivative. | |||
T0707L | Cyclophosphamide | DNA Alkylator/Crosslinker , DNA , MRP | |
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer. | |||
T19945 | N,N'-Carbonyldiimidazole | 1,1'-Carbonyldiimidazole,N,N'-Carbonyldiimidazole,CDI Crosslinker | Others |
N,N'-Carbonyldiimidazole is a biological cross-linking agent that has great application in mass spectrometry to detect the purity of compounds. | |||
T4368 | Miriplatin | SM-11355 | DNA Alkylator/Crosslinker |
Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC). | |||
T0923 | Busulfan | Myleran,Sulphabutin,Busulphan | Apoptosis , DNA Alkylator/Crosslinker , DNA Alkylation |
Busulfan (Busulphan) is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation... | |||
T1564 | Cisplatin | cis-Diaminodichloroplatinum,CDDP | DNA Alkylator/Crosslinker , Ferroptosis , DNA/RNA Synthesis , Autophagy |
Cisplatin (CDDP) is a DNA cross-linking agent. Cisplatin has antitumor activity and inhibits DNA synthesis by forming DNA adducts in cancer cells. Cisplatin also activates iron death and induces autophagy. | |||
T1055 | Ifosfamide | NSC109724,Isophosphamide | DNA Alkylator/Crosslinker , DNA/RNA Synthesis |
Ifosfamide (NSC-109724) alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic acti... | |||
T11120 | Duocarmycin TM | DNA Alkylation , Antibiotic | |
Duocarmycin TM is a DNA alkylator. Duocarmycin TM is an exceptionally potent antitumor antibiotic. | |||
T8554 | KCC-07 | DNA Alkylator/Crosslinker | |
KCC-07 is a selective, potent and brain-penetrant inhibitor of methyl-CpG-binding domain protein 2(MBD2) with anticancer activity. KCC-07 prevents binding of MBD2 to methylated DNA and activates brain specific angiogenes... | |||
T17159 | Treosulfan | NSC 39069,Treosulphan | DNA Alkylator/Crosslinker , DNA Alkylation |
Treosulfan (Treosulphan) is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types. | |||
T15793 | Lurbinectedin | PM01183 | Others |
Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity. | |||
T0164 | Oxaliplatin | L-OHP | DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy |
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autop... | |||
T5017 | Nimustine Hydrochloride | Nidran hydrochloride | Apoptosis , Others , DNA Alkylator/Crosslinker , DNA/RNA Synthesis |
Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma. | |||
T1058 | Carboplatin | NSC 241240,CBDCA,JM-8 | DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy |
Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity. | |||
T8380 | Bendamustine | SDX105 | Apoptosis , Others , DNA Alkylator/Crosslinker |
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia | |||
T1601 | Lomustine | CCNU,NSC 79037 | Apoptosis , Others , DNA Alkylator/Crosslinker , DNA Alkylation , Autophagy |
Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors. |
Cat No. | Product Name | Synonyms | Targets |
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T4558 | Trioxsalen | Trimethylpsoralen,Trioxysalen,Trisoralen | DNA Alkylator/Crosslinker , DHFR |
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, wh... | |||
T1507 | Streptozocin | STZ,Streptozotocin,NSC-85998,U 9889 | DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy |
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th... |