Search Result

Search Results for " 凋亡 "

Targets

1475

Compounds

407

Natural Products

Libraries

Cat No.	Product Name	Synonyms	Targets
T22119	NS3694		Apoptosis
	NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.		Apoptosis
T24784	SF5	SF-5,SF 5	Apoptosis
	SF5 is an inhibitor of the apoptosis pathway. Which is through the JNK-p53-caspase apoptotic cascade.		Apoptosis
T5485	OSU-T315	OSU-T315 (1,5-regioisomer),ILK-IN-2	Apoptosis , Integrin , Autophagy
	OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.		Apoptosis , Integrin , Autophagy
T64349	Necroptosis-IN-3	Cyclohexanecarboxamide, N-(2-thienylmethyl)-	Necroptosis
	Necroptosis-IN-3 (Cyclohexanecarboxamide, N-(2-thienylmethyl)-) (Compound 69) is a Necroptosis inhibitor that inhibits TNF-α induced necroptosis. Necroptosis-IN-3 (Compound STX1638) also inhibits 11β-HSD1.		Necroptosis
T9465	ZZW-115 hydrochloride		Apoptosis , Others
	ZZW-115 hydrochloride inhibits the activity of NUPR1.		Apoptosis , Others
T16540	Piperazine Erastin		Ferroptosis
	Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.		Ferroptosis
T1847	Necrostatin-1	Nec-1,Necrostatin 1	Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase
	Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO.
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T67699L	ALK/ROS1 inhibitor 2e HCL	(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)	Apoptosis
	ALK/ROS1 inhibitor 2e HCL possesses anti-apoptotic, anti-proliferative and anti-tumour activities.		Apoptosis
T77662	DJ4		Apoptosis
	DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.		Apoptosis
T1266	Terfenadine	(±)-Terfenadine,MDL-991	Apoptosis , Potassium Channel , 5-HT Receptor , Caspase , Na+/Ca2+ Exchanger , HER , AChR , Histamine Receptor
	Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.
T8978	DD1	3,3'-Diamino-4'-methoxyflavone,HUN85111	Proteasome
	DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T9003	CVT-11127		Dehydrogenase
	CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.		Dehydrogenase
T6191	Tasisulam	LY573636	Apoptosis , Caspase
	Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.		Apoptosis , Caspase
T22870	IPAG		Opioid Receptor
	IPAG is a potent σ-receptor antagonist (pKi=4.3). IPAG can induce cell apoptosis.		Opioid Receptor
T2453	BAM7		BCL
	BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).		BCL
T8331	NUN82647	CU-242	Others
	NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.		Others
T8969	API-1	NSC177223	Akt
	API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .		Akt
T21505	Suberoyl bis-hydroxamic acid	SBHA,Suberohydroxamic acid	Apoptosis , HDAC
	Suberoyl bis-hydroxamic acid (SBHA) is a Histone deacetylase (HDAC) inhibitor. HDAC is required for transcriptional modulation, cell cycle regulation and development. It is an enzyme that deacetylates lysine residues on ...		Apoptosis , HDAC
T33296	Merodantoin		Apoptosis
	Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin targets cancer cells expressing KRAS mutations involved in Akt-dependent ROS production.		Apoptosis
T9583	HJ-PI01	N-Acetylphenoxazine,10-acetylphenoxazine	Pim
	HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.		Pim
TQ0318L	ARRY 520 hydrochloride		KSP
	ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity.		KSP
T2425	KPT185	KPT-185,KPT 185	CRM1
	KPT185 (KPT 185) is a selective CRM1 inhibitor, inducing apoptosis, cell-cycle arrest.		CRM1
T7398	ONC212		Apoptosis , GPR
	ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.		Apoptosis , GPR
T6641	Rilmenidine Phosphate		Apoptosis , Adrenergic Receptor , Autophagy , Imidazoline Receptor
	Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.
T19777	ODQ		Apoptosis , Others , Guanylate cyclase
	ODQ is an effective and selective soluble guanylyl cyclase (sGC) inhibitor.		Apoptosis , Others , Guanylate cyclase
T9305	Necroptosis-IN-1		RIP kinase
	Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1.		RIP kinase
T4212	XMU-MP-1		Hippo pathway
	XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.		Hippo pathway
T6854	GSK621		Apoptosis , AMPK , Autophagy
	GSK621 is a specific and potent AMPK activator.		Apoptosis , AMPK , Autophagy
T2243	Serdemetan	JNJ-26854165	Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
	Serdemetan (JNJ-26854165) is an orally bioavailable HDM2 antagonist with potential antineoplastic activity.		Apoptosis , Mdm2 , E1/E2/E3 Enzyme , p53
T67769	MPT0B014		Microtubule Associated
	MPT0B014 is a potent tubulin polymerization inhibitor. MPT0B014 can induce cancer cell apoptosis.		Microtubule Associated
T6149	YH239-EE		Apoptosis , E1/E2/E3 Enzyme
	YH239-EE, the ethyl ester of YH239, is a potent p53-MDM2 antagonist and an apoptosis inducer.		Apoptosis , E1/E2/E3 Enzyme
T5210	BAI1		Apoptosis , BCL
	BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).		Apoptosis , BCL
T63399L	MTOR/HDAC-IN-1 HCl	mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)	HDAC , mTOR
	mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.		HDAC , mTOR
T28206	NSC49652	NSC 49652,NSC-49652	Apoptosis
	NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.		Apoptosis
T5822	BTR-1	5-Benzylidene-3-ethyl rhodanine	Apoptosis
	5-Benzylidene-3-ethyl rhodanine(BTR-1 (5-Benzylidene-3-ethyl rhodanine)) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.		Apoptosis
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
T3953	Salermide		Apoptosis , Sirtuin
	Salermide is an inhibitor of Sirt1 and Sirt2, causing strong cancer-specific apoptotic cell death.		Apoptosis , Sirtuin
T31987	Gossypolone		Wnt/beta-catenin , Gamma-secretase
	Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.		Wnt/beta-catenin , Gamma-secretase
T8866	GW779439X		Apoptosis , Antibacterial , CDK , Aurora Kinase
	GW779439X is an inhibitor of CDK.		Apoptosis , Antibacterial , CDK , Aurora Kinase
T6428	BV6		IAP
	BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.		IAP
T9712	PF07104091	PF-07104091	CDK
	PF07104091 inhibits CDK2, which may lead to cell cycle arrest, induce apoptosis and inhibit tumor cell proliferation.		CDK
T2111	Sepantronium bromide	YM155	Survivin , Autophagy
	Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.		Survivin , Autophagy
T16754	RIPGBM		Apoptosis
	RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).		Apoptosis
T77332	TV 3279		BCL , PKC
	TV 3279 is a novel ChE-MAI inhibitor , and the neuroprotective properties depend on their ability to induce the anti-apoptotic proteins PKC, Bcl-2, Bcl-x, and SOD, and to block the nuclear translocation of the pro-apopto...		BCL , PKC
T12085	MN58b		Apoptosis , AChR
	MN58b is a selective inhibitor of choline kinase α (CHKα).		Apoptosis , AChR
T1950	PND-1186	PND1186,PND 1186,VS-4718,SR-2516	Apoptosis , FAK
	PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).		Apoptosis , FAK
T38563	Raptinal		Caspase
	Raptinal activates caspase-3 directly and initiates intrinsic caspase-dependent apoptosis pathway in multiple cell lines.		Caspase
T9083	TC11	CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11	BCL , Caspase , CDK
	TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) is a potent inhibitor of tumor cell proliferation and an inducer of apoptosis via activation of caspase-3, 8 and 9.		BCL , Caspase , CDK
T77346	2-aminobenzo[d]thiazol-6-ol
	2-aminobenzo[d]thiazol-6-ol has antimicrobial, antioxidant and anticancer properties and may inhibit the activity of certain cancer cell lines by inducing apoptosis or programmed cell death.

Compounds

Synonym: OSU-T315 (1,5-regioisomer),ILK-IN-2

Target: Apoptosis, Integrin, Autophagy

Necroptosis-IN-3

T64349

Synonym: Cyclohexanecarboxamide, N-(2-thienylmethyl)-

Target: Necroptosis

ZZW-115 hydrochloride

T9465

Synonym:

Target: Apoptosis, Others

Synonym: Nec-1,Necrostatin 1

Target: Indoleamine 2,3-Dioxygenase (IDO), Ferroptosis, Autophagy, RIP kinase

ALK/ROS1 inhibitor 2e HCL

T67699L

Synonym: (R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride(2365497-12-5 Free base)

Synonym: (±)-Terfenadine,MDL-991

Target: Apoptosis, Potassium Channel, 5-HT Receptor, Caspase, Na+/Ca2+ Exchanger, HER, AChR, Histamine Receptor

DD1

T8978

Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111

Target: Dehydrogenase

Tasisulam

T6191

Synonym: LY573636

Target: Apoptosis, Caspase

IPAG

T22870

Synonym:

Target: Opioid Receptor

Suberoyl bis-hydroxamic acid

T21505

Synonym: SBHA,Suberohydroxamic acid

Target: Apoptosis, HDAC

Synonym: N-Acetylphenoxazine,10-acetylphenoxazine

Target: Pim

ARRY 520 hydrochloride

Synonym: KPT-185,KPT 185

Target: Apoptosis, GPR

Rilmenidine Phosphate

T6641

Synonym:

Target: Apoptosis, Adrenergic Receptor, Autophagy, Imidazoline Receptor

ODQ

T19777

Synonym:

Target: Apoptosis, Others, Guanylate cyclase

Target: Hippo pathway

GSK621

T6854

Synonym:

Target: Apoptosis, AMPK, Autophagy

Serdemetan

T2243

Synonym: JNJ-26854165

Target: Apoptosis, Mdm2, E1/E2/E3 Enzyme, p53

MPT0B014

T67769

Synonym:

Target: Microtubule Associated

YH239-EE

T6149

Synonym:

Target: Apoptosis, E1/E2/E3 Enzyme

BAI1

T5210

Synonym:

Target: Apoptosis, BCL

mTOR/HDAC-IN-1 HCl

T63399L

Synonym: mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)

Target: HDAC, mTOR

NSC49652

T28206

Synonym: NSC 49652,NSC-49652

Target: Apoptosis

BTR-1

T5822

Synonym: 5-Benzylidene-3-ethyl rhodanine

Target: Apoptosis, Sirtuin

Gossypolone

T31987

Synonym:

Target: Wnt/beta-catenin, Gamma-secretase

GW779439X

T8866

Synonym:

Target: Apoptosis, Antibacterial, CDK, Aurora Kinase

Target: Survivin, Autophagy

Target: Apoptosis, AChR

PND-1186

T1950

Synonym: PND1186,PND 1186,VS-4718,SR-2516

Target: Apoptosis, FAK

Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

Target: BCL, Caspase, CDK

2-aminobenzo[d]thiazol-6-ol

T77346

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
TN1153	Polyporenic acid C		Apoptosis , PARP , Caspase , PI3K
	Polyporenic acid C shows inhibitory activity against human collagenase.		Apoptosis , PARP , Caspase , PI3K
T8092	Taurohyodeoxycholic acid sodium salt	Sodium taurohyodeoxycholate hydrate	Caspase
	Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.		Caspase
T6485	Embelin	NSC 91874,Emberine,Embelic acid	Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
	Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T2799	(20S)-Protopanaxadiol	20-Epiprotopanaxadiol,20(S)-APPD	Apoptosis , Reactive Oxygen Species , P-gp
	(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin.		Apoptosis , Reactive Oxygen Species , P-gp
T8245	3,4-Dihydroxyflavone		Others
	3,4-Dihydroxyflavone Acts as an Antioxidant and Antiapoptotic Agent .		Others
T3916	Ginsenoside F2		Apoptosis , Endogenous Metabolite , Autophagy
	Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.		Apoptosis , Endogenous Metabolite , Autophagy
TJA2398	Taurodeoxycholic acid sodium hydrate	Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt	Apoptosis , Caspase
	Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.		Apoptosis , Caspase
T2S0500	Ilexsaponin A	Ilexsaponin A1	Others
	1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.		Others
TN3110	5-Geranoxy-7-methoxycoumarin		Anti-infection , Antibacterial , Antifungal
	5-Geranoxy-7-methoxycoumarin shows antifungal activity.		Anti-infection , Antibacterial , Antifungal
T3759	3,4-Dimethoxycinnamic acid	Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid	Apoptosis , Virus Protease , Reactive Oxygen Species
	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) is a monomer found in Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated...		Apoptosis , Virus Protease , Reactive Oxygen Species
T5715	(E)-Flavokawain A	FLAVOKAVAIN A(P)	Apoptosis , P450
	(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.		Apoptosis , P450
T2829	Isoalantolactone	(+)-Isoalantolactone,Isohelenin	Apoptosis , Endogenous Metabolite , Antibacterial , Autophagy
	Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.
T5574	Guggulsterone	Guggulsterone E&Z	Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
	Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.		Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
T6S2315	Polyphyllin VI		Apoptosis , Antibacterial , Pyroptosis
	1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.		Apoptosis , Antibacterial , Pyroptosis
T22417	Rutin hydrate	Rutoside,Sophorin,Quercetin-3-O-rutinoside	Beta Amyloid , Others , Autophagy
	Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.		Beta Amyloid , Others , Autophagy
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
TN1417	Azadirachtin		Apoptosis , Antifection
	Azadirachtin has antifungal activity, used as an insecticide.		Apoptosis , Antifection
T6S1652	Benzoylpaeoniflorin		COX
	1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.		COX
T0795	Rutin	Quercetin 3-O-rutinoside,Rutoside	Beta Amyloid , Prostaglandin Receptor , Autophagy
	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.		Beta Amyloid , Prostaglandin Receptor , Autophagy
T8057	Citronellyl acetate		Apoptosis , Others
	Citronellyl acetate is a natural product		Apoptosis , Others
T5S1252	Prosapogenin A	Progenin III	Apoptosis , Others
	Prosapogenin A (Progenin III) has anticancer activity.		Apoptosis , Others
TN3594	Cardanol (C15:1)		Apoptosis , Others
	Cardanol (C15:1), found in cashew nut shell liquid, induces mitochondria-associated apoptosis in human melanoma cells.		Apoptosis , Others
T4818	Thyminose	2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose	Others , Endogenous Metabolite
	Thyminose (2-Deoxy-D-arabinose) induces Apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.		Others , Endogenous Metabolite
T19720	Colcemid	C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine	Microtubule Associated
	Colcemid (NSC-3096) is an inhibitor of microtubule polymerization. It used to study embryonic cloning.		Microtubule Associated
T2882	Genistin	Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside	Apoptosis , Estrogen Receptor/ERR , Others
	Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities		Apoptosis , Estrogen Receptor/ERR , Others
T2791	Pectolinarin		Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
	Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T6S1435	Notopterol		Apoptosis , Others
	1. Notopterol induces apoptosis and inhibits cell cycle-specific.		Apoptosis , Others
T5A2461	Bufotalin	Bufotaline	Apoptosis , Others , Reactive Oxygen Species
	1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.		Apoptosis , Others , Reactive Oxygen Species
T0129	Sanguinarine chloride	Pseudochelerythrine chloride,Sanguinarium chloride	Apoptosis , EGFR , VEGFR , Antibacterial , Parasite , Autophagy
	Sanguinarine chloride (Pseudochelerythrine chloride), a benzophenanthridine alkaloid, stimulates apoptosis by activating the production of reactive oxygen species (ROS).
T6S0325	Glycitein	Glycetein	Apoptosis , Others
	1. Gycitein has weak estrogenic activity. 2. Glycitein (Glycetein) inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression.		Apoptosis , Others
T15544	Iberin	NSC 321801	Endogenous Metabolite
	Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane.		Endogenous Metabolite
T6S1292	Levistolide A	Levistilide A,Diligustilide	Apoptosis , Others
	1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.		Apoptosis , Others
TN1839	Kumatakenin	Jaranol,Kaempferol 3,7-O-dimethyl ether	Apoptosis , Anti-infection
	Kumatakenin can suppress >80% of the SOS-inducing activity of Trp-P-1 at <0.06 micromol/mL.		Apoptosis , Anti-infection
TN1856	Leachianone A	Isokurarinone	SGLT
	Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.		SGLT
T5S2076	Senkyunolide I		Others , Caspase
	1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.		Others , Caspase
T3862	Irigenin		NF-κB , Integrin
	Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra Domain A domain. It can sensitize TRAIL-induced apoptosis by enha...		NF-κB , Integrin
TN1586	Dihydrorotenone		Apoptosis , Mitochondrial Metabolism
	Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.		Apoptosis , Mitochondrial Metabolism
T5740	25(R,S)-Ruscogenin	(25RS)-Ruscogenin	Others , HIF
	25(R,S)-Ruscogenin is a natual product.		Others , HIF
TN2103	PROCYANIDIN C1		Apoptosis
	Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.		Apoptosis
T2959	Ginsenoside Rh2	20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2	Apoptosis , EGFR , Caspase , Endogenous Metabolite
	Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.		Apoptosis , EGFR , Caspase , Endogenous Metabolite
T3055	Liensinine Perchlorate		Apoptosis , Others
	Liensinine is the active constituent of plumula nelambinis with anti-hypertension.		Apoptosis , Others
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
T0968	Paclitaxel	Taxol,NSC 125973	Apoptosis , Microtubule Associated , Autophagy
	Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.		Apoptosis , Microtubule Associated , Autophagy
T5607	Geranyl acetate		Apoptosis , Others
	Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.		Apoptosis , Others
T2565	Hesperetin		Apoptosis , p38 MAPK , 5-HT Receptor , Autophagy , TGF-beta/Smad
	Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
T6407	β-Lapachone	Beta-Lapachone,NSC-26326,SL-11001,ARQ-501	IDO , Apoptosis , Topoisomerase , Autophagy
	β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.		IDO , Apoptosis , Topoisomerase , Autophagy
T5776	Pimpinellin		Apoptosis , Anti-infection
	Pimpinellin is a natural product that acts as antagonist of proteins with GABA receptor activity.		Apoptosis , Anti-infection
T5798	Euphorbia Factor L2	euphorbiafactor L2	Apoptosis , NF-κB
	Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.		Apoptosis , NF-κB
TN1493	Chrysosplenol D		IL Receptor , NF-κB , JNK
	Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.		IL Receptor , NF-κB , JNK
T3396	Baohuoside I	Icariside-II,Icariin-II	Apoptosis , CXCR
	Baohuoside I (Icariside-II) is a component of Epimedium koreanum, exhibits anti-inflammatory activity and anti-osteoporosis activities.		Apoptosis , CXCR
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Natural Products

Polyporenic acid C

TN1153

Synonym:

Target: Apoptosis, PARP, Caspase, PI3K

Taurohyodeoxycholic acid sodium salt

T8092

Synonym: Sodium taurohyodeoxycholate hydrate

Target: Caspase

Embelin

T6485

Synonym: NSC 91874,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

(20S)-Protopanaxadiol

T2799

Synonym: 20-Epiprotopanaxadiol,20(S)-APPD

Target: Apoptosis, Reactive Oxygen Species, P-gp

Target: Apoptosis, Endogenous Metabolite, Autophagy

Taurodeoxycholic acid sodium hydrate

TJA2398

Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt

Target: Apoptosis, Caspase

Ilexsaponin A

T2S0500

Synonym: Ilexsaponin A1

Target: Others

5-Geranoxy-7-methoxycoumarin

TN3110

Synonym:

Target: Anti-infection, Antibacterial, Antifungal

3,4-Dimethoxycinnamic acid

T3759

Synonym: Dimethylcaffeic acid,Caffeic acid dimethyl ether,O-Methylferulic acid

Target: Apoptosis, Virus Protease, Reactive Oxygen Species

(E)-Flavokawain A

T5715

Synonym: FLAVOKAVAIN A(P)

Target: Apoptosis, P450

Isoalantolactone

T2829

Synonym: (+)-Isoalantolactone,Isohelenin

Target: Apoptosis, Endogenous Metabolite, Antibacterial, Autophagy

Guggulsterone

T5574

Synonym: Guggulsterone E&Z

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Polyphyllin VI

T6S2315

Synonym:

Target: Apoptosis, Antibacterial, Pyroptosis

Rutin hydrate

T22417

Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside

Target: Beta Amyloid, Others, Autophagy

Naphthazarin

T8678

Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Target: Apoptosis, Antifection

Synonym: Quercetin 3-O-rutinoside,Rutoside

Target: Beta Amyloid, Prostaglandin Receptor, Autophagy

Citronellyl acetate

T8057

Synonym:

Target: Apoptosis, Others

Prosapogenin A

T5S1252

Synonym: Progenin III

Target: Apoptosis, Others

Cardanol (C15:1)

TN3594

Synonym:

Target: Apoptosis, Others

Thyminose

T4818

Synonym: 2-Deoxy-D-ribose,2-Deoxy-D-arabinose,2-Deoxy-D-erythropentose

Target: Others, Endogenous Metabolite

Colcemid

T19720

Synonym: C 12669,C-12669,NSC-3096,Kolchicin,C12669,Demecolcine

Target: Microtubule Associated

Genistin

T2882

Synonym: Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside

Target: Apoptosis, Estrogen Receptor/ERR, Others

Pectolinarin

T2791

Synonym:

Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin

Notopterol

T6S1435

Synonym:

Target: Apoptosis, Others

Bufotalin

T5A2461

Synonym: Bufotaline

Target: Apoptosis, Others, Reactive Oxygen Species

Sanguinarine chloride

T0129

Synonym: Pseudochelerythrine chloride,Sanguinarium chloride

Target: Apoptosis, EGFR, VEGFR, Antibacterial, Parasite, Autophagy

Glycitein

T6S0325

Synonym: Glycetein

Target: Apoptosis, Others

Iberin

T15544

Synonym: NSC 321801

Target: Endogenous Metabolite

Levistolide A

T6S1292

Synonym: Levistilide A,Diligustilide

Target: Apoptosis, Others

Kumatakenin

TN1839

Synonym: Jaranol,Kaempferol 3,7-O-dimethyl ether

Target: Apoptosis, Anti-infection

Leachianone A

TN1856

Synonym: Isokurarinone

Target: Others, Caspase

Irigenin

T3862

Synonym:

Target: NF-κB, Integrin

Dihydrorotenone

TN1586

Synonym:

Target: Apoptosis, Mitochondrial Metabolism

25(R,S)-Ruscogenin

T5740

Synonym: (25RS)-Ruscogenin

Synonym: 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2

Target: Apoptosis, EGFR, Caspase, Endogenous Metabolite

Liensinine Perchlorate

T3055

Synonym:

Target: Apoptosis, Others

Isosilybin A

TN1804

Synonym:

Target: Apoptosis, Tyrosinase, PPAR, ABC

Paclitaxel

T0968

Synonym: Taxol,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

Geranyl acetate

T5607

Synonym:

Target: Apoptosis, Others

Hesperetin

T2565

Synonym:

Target: Apoptosis, p38 MAPK, 5-HT Receptor, Autophagy, TGF-beta/Smad

β-Lapachone

T6407

Synonym: Beta-Lapachone,NSC-26326,SL-11001,ARQ-501

Target: IDO, Apoptosis, Topoisomerase, Autophagy

pimpinellin

T5776

Synonym:

Target: Apoptosis, Anti-infection

Euphorbia Factor L2

T5798

Synonym: euphorbiafactor L2

Target: Apoptosis, NF-κB

Chrysosplenol D

TN1493

Synonym:

Target: IL Receptor, NF-κB, JNK

Baohuoside I

T3396

Synonym: Icariside-II,Icariin-II

Target: Apoptosis, CXCR

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Cat No.	Product Name
L9000	Apoptosis Compound Library	1796 compounds
	A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
L8700	Ferroptosis Compound Library	800 compounds
	A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；
L8710	Cuproptosis Compound Library	411 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 411 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L5300	Mitochondria-Targeted Compound Library	830 compounds
	A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L9420	Exosome Compound Library	80 compounds
	80 exosome-related compounds that can be used for high-throughput and high-content screening.
L3800	NF-κB Signaling Compound Library	740 compounds
	A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L6100	Polyphenolic Natural Product Library	640 compounds
	A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);
L1100	Protease Inhibitor Library	344 compounds
	A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;
L1110	Microtubule-Targeted Compound Library	155 compounds
	A unique collection of 155 microtubule-targeted compounds can be used in HTS and HCS;
L3200	Autophagy Compound Library	1248 compounds
	A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L3980	DNA Damage and Repair Compound Library Plus	667 compounds
	Well-chosen 667 compounds with unique structures targeting DNA damage & repair;
L2160	Anti-Cancer Active Compound Library	3250 compounds
	A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2150	Anti-Cancer Drug Library	3159 compounds
	A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L1610	FDA-Approved Kinase Inhibitor Library	266 compounds
	A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L2100	Anti-Cancer Compound Library	7360 compounds
	A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L8600	Ubiquitination Compound Library	214 compounds
	A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening；
L2120	Anti-Cancer Clinical Compound Library	2614 compounds
	A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L6740	Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library	386 compounds
	A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.
L8100	Cell Cycle Compound Library	695 compounds
	A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L4100	TGF-beta/Smad Compound Library	185 compounds
	A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
L2110	Anti-Cancer Approved Drug Library	1825 compounds
	A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L7900	Osteogenesis Compound Library	320 compounds
	A unique collection of 320 osteogenesis related compounds for high throughput and high content screening;
L1300	PI3K-AKT-mTOR Compound Library	425 compounds
	A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;
L4300	Wnt/Hedgehog/Notch Compound Library	240 compounds
	A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L6810	Traditional Chinese Medicine Monomer Library	2688 compounds
	A unique collection of 2688 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism；
L6800	Chinese Pharmacopoeia Natural Product Library	2070 compounds
	A unique collection of 2070 natural products included in Chinese Pharmacopoeia (CP), a powerful tool for drug development and pharmacological study;
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.