Search Result

Search Results for " α-glucosidase "

Compounds

Natural Products

Cat No.	Product Name	Synonyms	Targets
T41028	α-Glucosidase	α-D-Glucosidase
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the sma...
T67898	α-Glucosidase-IN-22		Glucosidase
	α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.		Glucosidase
T67728	α-Glucosidase-IN-23		Glucosidase
	α-Glucosidase-IN-23 is an orally active α-Glucosidase inhibitor. α-Glucosidase-IN-23 can decrease blood glucose by α-glucosidase inhibition (IC50= 4.48 μM).		Glucosidase
T60715	α-Glucosidase-IN-4		Glucosidase
	α-Glucosidase-IN-4 is a potent α-glucosidase inhibitor with antihypertensive and hypoglycemic activity.		Glucosidase
T61706	α-Amylase/α-Glucosidase-IN-2
	α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μM and 13.09 μM, respectively. This compound shows promise for in...
T79225	α-Amylase/α-Glucosidase-IN-3		Glucosidase
	α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM, respectively. It is applicable for type-II diabetes mellitu...		Glucosidase
T63562	α-Glucosidase-IN-14
	α-Glucosidase-IN-14 is a potent inhibitor of α-glucosidase (IC50: 5.22 μM).
T62222	α-Glucosidase-IN-11
	α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM). α-Glucosidase-IN-11 binds to the Trp residue in α-glucosidase and has a regulatory effect on protein folding and can be us...
T61519	α-Glucosidase-IN-18
	α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM. This compound exhibits antidiabetic properties [1].
T61166	α-Glucosidase-IN-16
	α-Glucosidase-IN-16 is a highly effective and orally bioavailable inhibitor of α-glucosidase, displaying a remarkable IC50 value of 3.28 μM. This compound demonstrates the ability to significantly decrease blood glucose ...
T61124	α-Glucosidase-IN-9
	α-Glucosidase-IN-9 (compound 7) is a highly potent α-glucosidase inhibitor with an IC50 of 55.6 μM, making it suitable for type II diabetes research [1].
T60389	α-Glucosidase-IN-5
	α-Glucosidase-IN-5 (compound 8) is isolated from a twig extract of Polyalthia cinnamomea which is a potent α-glucosidase inhibitor with an IC50 of 57.9 µM. α-Glucosidase-IN-5 has the potential for the research of diabete...
T79237	α-Glucosidase-IN-27		Glucosidase
	α-Glucosidase-IN-27 (compound 8l), an α-glucosidase inhibitor with an IC50 value of 25.78 μM, demonstrates potential for research into type 2 diabetes (D2M) [1].		Glucosidase
T78794	α-Glucosidase-IN-31		Glucosidase
	α-Glucosidase-IN-31 (compound R1) is a potent oral α-Glucosidase inhibitor with an IC50 of 10.1 μM, demonstrating significant blood glucose reduction and antidiabetic activity [1].		Glucosidase
T80709	α-Glucosidase-IN-41		Glucosidase
	α-Glucosidase-IN-41 (compound 5o), a potent inhibitor of α-glucosidase, induces alterations in the secondary structure of the enzyme, thereby impeding its catalytic function. This compound is utilized in the study of dia...		Glucosidase
T79700	α-Glucosidase-IN-32		Glucosidase
	α-Glucosidase-IN-32 (compound f26) is a reversible, noncompetitive inhibitor of α-glucosidase that is orally active and exhibits an IC50 of 3.07 μM. It forms a complex with α-glucosidase via hydrogen bonding and hydropho...		Glucosidase
T78740	α-Glucosidase-IN-28		Glucosidase
	α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM. It interacts with the enzyme's original binding site (OBS) and establishes multiple hydrophobic interaction...		Glucosidase
T60255	α-Amylase/α-Glucosidase-IN-1
	α-Amylase/α-Glucosidase-IN-1 (compound 33) is an effective inhibitor of α-amylase/α-glucosidase with IC 50 s of 2.01, 2.09 μM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucos...
T79402	α-Amylase/α-Glucosidase-IN-4		Glucosidase
	α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50 values of 1.10 μM and 0.15 μM respectively. This compound i...		Glucosidase
T80715	α-Amylase/α-Glucosidase-IN-6
	α-Amylase/α-Glucosidase-IN-6 (compound 5j) serves as a potent dual inhibitor of both α-amylase and α-glucosidase, exhibiting IC50 values of 17.0 µM and 40.1 µM, respectively. It demonstrates anti-hyperglycemic activities...
T78878	α-Amylase/α-Glucosidase-IN-5		Glucosidase
	α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50 values of 5.96 μM and 1.62 μM, respectively, exhibiting...		Glucosidase
T63310	α-Glucosidase-IN-6
	α-Glucosidase-IN-6 is a competitive inhibitor of α-glucosidase (IC50: 5.69 μM) and exhibits potential for anti-diabetic studies.
T61503	α-Glucosidase-IN-15
	α-Glucosidase-IN-15 (Compound 14B) exhibits potent inhibitory activity against α-glucosidase, with an IC50 value of 3.34 μM. It possesses antidiabetic properties [1].
T62972	α-Glucosidase-IN-17
	α-Glucosidase-IN-17 (Compound 12B) is a potent and orally active inhibitor of α-glucosidase, demonstrating antidiabetic activity with an inhibitory concentration (IC50) of 3.79 μM [1].
T80711	α-Glucosidase-IN-39		Glucosidase
	α-Glucosidase-IN-39 is a potent α-glucosidase enzyme inhibitor, exhibiting an IC50 value of 869.06 ppm. It is applicable for use in antidiabetic studies [1].		Glucosidase
T61761	α-Glucosidase-IN-21
	α-Glucosidase-IN-21 (Compound 2B) is a highly potent and orally bioavailable inhibitor of α-glucosidase. With an impressive IC50 value of 2.62 μM, this compound exhibits remarkable anti-diabetic properties [1].
T61331	α-Glucosidase-IN-20
	α-Glucosidase-IN-20 (Compound 3B) is a highly effective and orally active inhibitor of α-glucosidase. It exhibits potent anti-diabetic properties, as evidenced by its IC50 value of 3.01 μM [1].
T78864	α-Glucosidase-IN-33		Glucosidase
	α-Glucosidase-IN-33 (compound 7c), with an IC50 of 2.39 μM, is a potent inhibitor of α-glucosidase and is relevant in research on type 2 diabetes and hyperglycemia [1].		Glucosidase
T78865	α-Glucosidase-IN-34		Glucosidase
	α-Glucosidase-IN-34 (compound 7f) is a potent inhibitor of α-glucosidase, exhibiting an IC50 of 2.90 μM, and is applicable in research related to type 2 diabetes and hyperglycemia [1].		Glucosidase
T80708	α-Glucosidase-IN-42		Glucosidase
	α-Glucosidase-IN-42 (Compound 26), a 9-O-berberrubine carboxylate derivative, exhibits potent α-glucosidase inhibitory activity with an IC50 value of 1.61 μM and has potential for use in antidiabetic research [1].		Glucosidase
T78741	α-Glucosidase-IN-29		Glucosidase
	α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM. This compound is utilized in the research of diabetes and related diseases [1].		Glucosidase
T63361	α-Glucosidase-IN-13
	α-Glucosidase-IN-13 is an inhibitor of α-glucosidase (IC50: 5.69 μM).
T63574	α-Glucosidase-IN-12
	α-Glucosidase-IN-12 is a potent inhibitor of α-glucosidase (IC50: 10.20 μM).
T62994	α-Glucosidase-IN-10
	α-Glucosidase-IN-10 (compound 13) is a potent inhibitor of α-glucosidase (IC50: 92.7 μM). α-Glucosidase-IN-10 can be used to study type II diabetes.
T64230	α-Glucosidase-IN-3
	α-Glucosidase-IN-3 is an oleanolic acid oxime ester derivative targeting α-glucosidase and α-amylase with an IC50 value of 0.35 μM for α-glucosidase.
T61249	α-Glucosidase-IN-2
	α-Glucosidase-IN-2 (compound 5d) is a potent inhibitor of α-Glucosidase, exhibiting an inhibitory concentration (IC50) of 9.48 μM, and functions as an antidiabetic agent [1].
T61094	α-Glucosidase-IN-8
	α-Glucosidase-IN-8 (Compound 4k) is a potent, competitive inhibitor of α-glucosidase. It displays an impressive IC50 value of 0.18 μg/mL [1].
T80710	α-Glucosidase-IN-40		Glucosidase
	α-Glucosidase-IN-40 (compound 5) serves as a noncompetitive inhibitor of the α-glucosidase enzyme, exhibiting an inhibitory concentration (IC50) of 24.62 μM [1].		Glucosidase
T80712	α-Glucosidase-IN-38		Glucosidase
	α-Glucosidase-IN-38 (Compound 11j) is a potent α-glucosidase inhibitor, demonstrating an IC50 of 12.44±0.38 μM, and is significant in the context of Diabetes mellitus (DM) management [1].		Glucosidase
T78731	α-Glucosidase-IN-26		Glucosidase
	α-Glucosidase-IN-26 (Compound 7i), with an IC50 value of 4.63 µM, functions as an α-glucosidase inhibitor and is utilized in research related to type 2 diabetes mellitus (T2DM) [1].		Glucosidase
T79259	α-Glucosidase-IN-25		Glucosidase
	α-Glucosidase-IN-25 (Compound (R)-8k) serves as a competitive inhibitor for α-glucosidase, demonstrating an inhibitory concentration 50 (IC50) of 1.19μM, making it applicable in anti-diabetic research [1].		Glucosidase
T78881	α-Glucosidase-IN-36		Glucosidase
	α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65 μM and 4.54 μM, respectively. It is hypothesized to suppres...		Glucosidase
T62891	α-Glucosidase-IN-19
	Alpha-Glucosidase-IN-19 (Compound 6B) is an orally active alpha-glucosidase inhibitor (IC50: 3.63 μM) with antidiabetic effects.
T79318	α-Glucosidase-IN-30		Glucosidase
	α-Glucosidase-IN-30 (compound 8c) is a potent, orally active competitive inhibitor of α-glucosidase, exhibiting a K i of 40.0 µM and an IC50 of 49.0 µM. It is non-cytotoxic to both cancerous MCF-7 and normal HDF cell lin...		Glucosidase
T10755L	Celgosivir	MX3253,MBI 3253,6 O-butanoyl castanospermine,MDL 28574	Glucosidase
	Celgosivir (6 O-butanoyl castanospermine) is an inhibitor of α-glucosidase I. In vitro assay, it inhibits bovine viral diarrhoea virus (BVDV) ( IC50: 1.27 μM ).		Glucosidase
T38894	IHVR-17028		Influenza Virus , Glucosidase
	IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity. IHVR-17028 inhibited BVDV, TCRV and DENV, and EC50 values were 0.4 μM, 0.26 μM and 0.3 μM,...		Influenza Virus , Glucosidase
T7858	Ceftezole sodium	Celoslin,Falomesin,Alomen	Anti-infection , Antibacterial , Antibiotic , Glucosidase
	Ceftezole sodium (Falomesin) is a broad-spectrum cephalosporin antibiotic active gram-negative and gram-positive bacteria except for Proteus vulgaris, Pseudomonas aeruginosa, and Serratia marcescens. It has the inhibitio...		Anti-infection , Antibacterial , Antibiotic , Glucosidase
T10751	Cefetrizole		Glucokinase
	Ceftezole is an α-Glucosidase inhibitor (IC50: 2.1 μM; Ki: 0.578 μM).		Glucokinase
T10755	Celgosivir hydrochloride	MX3253 hydrochloride,MBI 3253 hydrochloride,MDL 28574 hydrochloride	Others
	Celgosivir hydrochloride (MBI 3253 hydrochloride) is an α-glucosidase I inhibitor and inhibits bovine viral diarrhoea virus (BVDV) (IC50: 1.27 μM).		Others
T12151	N-Methylmoranoline	MOR 14,N-Methyl-1-deoxynojirimycin,N-Methylmoranolin	Others
	N-Methylmoranoline is an inhibitor of α-glucosidase.		Others

Compounds

α-Glucosidase

T41028

Synonym: α-D-Glucosidase

Target:

α-Glucosidase-IN-22

T67898

Synonym:

Target: Glucosidase

α-Glucosidase-IN-23

T67728

Synonym:

Target: Glucosidase

α-Glucosidase-IN-4

T60715

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-2

T61706

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-3

T79225

Synonym:

Target: Glucosidase

α-Glucosidase-IN-14

T63562

Synonym:

Target:

α-Glucosidase-IN-11

T62222

Synonym:

Target:

α-Glucosidase-IN-18

T61519

Synonym:

Target:

α-Glucosidase-IN-16

α-Glucosidase-IN-27

T79237

Synonym:

Target: Glucosidase

α-Glucosidase-IN-31

T78794

Synonym:

Target: Glucosidase

α-Glucosidase-IN-41

T80709

Synonym:

Target: Glucosidase

α-Glucosidase-IN-32

T79700

Synonym:

Target: Glucosidase

α-Glucosidase-IN-28

T78740

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-1

T60255

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-4

T79402

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-6

T80715

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-5

T78878

Synonym:

Target: Glucosidase

α-Glucosidase-IN-15

T61503

Synonym:

Target:

α-Glucosidase-IN-17

T62972

Synonym:

Target:

α-Glucosidase-IN-39

T80711

Synonym:

Target: Glucosidase

α-Glucosidase-IN-21

T61761

Synonym:

Target:

α-Glucosidase-IN-20

T61331

Synonym:

Target:

α-Glucosidase-IN-33

T78864

Synonym:

Target: Glucosidase

α-Glucosidase-IN-34

T78865

Synonym:

Target: Glucosidase

α-Glucosidase-IN-42

T80708

Synonym:

Target: Glucosidase

α-Glucosidase-IN-29

T78741

Synonym:

Target: Glucosidase

α-Glucosidase-IN-13

T63361

Synonym:

Target:

α-Glucosidase-IN-12

T63574

Synonym:

Target:

α-Glucosidase-IN-10

α-Glucosidase-IN-40

T80710

Synonym:

Target: Glucosidase

α-Glucosidase-IN-38

T80712

Synonym:

Target: Glucosidase

α-Glucosidase-IN-26

T78731

Synonym:

Target: Glucosidase

α-Glucosidase-IN-25

T79259

Synonym:

Target: Glucosidase

α-Glucosidase-IN-36

T78881

Synonym:

Target: Glucosidase

α-Glucosidase-IN-19

T62891

Synonym:

Target:

α-Glucosidase-IN-30

T79318

Synonym:

Target: Glucosidase

Celgosivir

T10755L

Synonym: MX3253,MBI 3253,6 O-butanoyl castanospermine,MDL 28574

Target: Glucosidase

IHVR-17028

T38894

Synonym:

Target: Influenza Virus, Glucosidase

Ceftezole sodium

T7858

Synonym: Celoslin,Falomesin,Alomen

Target: Anti-infection, Antibacterial, Antibiotic, Glucosidase

Celgosivir hydrochloride

T10755

Synonym: MX3253 hydrochloride,MBI 3253 hydrochloride,MDL 28574 hydrochloride

Target: Others

N-Methylmoranoline

T12151

Synonym: MOR 14,N-Methyl-1-deoxynojirimycin,N-Methylmoranolin

Target: Others

Cat No.	Product Name	Synonyms	Targets
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
TN6771	Malabaricone B		Others
	Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.		Others
TN1990	Norathyriol		Akt , DNA/RNA Synthesis , AMPK , PPAR
	Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.		Akt , DNA/RNA Synthesis , AMPK , PPAR
T8319	Butyl isobutyl phthalate	ButylIsobutylPhthalate	Glucosidase
	Butyl isobutyl phthalate (ButylIsobutylPhthalate) is a non-competitive α-glucosidase inhibitor(IC50 :38 μM),it shows a hypoglycemic effect		Glucosidase
T75612	α-Glucosidase-IN-24
	α-Glucosidase-IN-24 (Compound 13), an α-Glucosidase inhibitor, exhibits an IC50 value of 451 μM and can be derived from Swertia kouitchensis [1].
T80713	α-Glucosidase-IN-37
	α-Glucosidase-IN-37 (Compound 11) moderately inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, exhibiting an inhibitory concentration 50 (IC50) value of 23.7 μM. Additionally, this co...
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
TN2144	Resveratroloside		P450 , NO Synthase
	Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.		P450 , NO Synthase
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
T3235	Rebaudioside A	Reb-A 97,Reb A,Stevioside A3,Glycoside A3	Endogenous Metabolite , Glucosidase
	Rebaudioside A (Reb A) is a novel agent of glycoside clathration of pharmacons, acts as α-glucosidase inhibitor.		Endogenous Metabolite , Glucosidase
T12142	N-Caffeoyl O-methyltyramine		Glucosidase
	N-Caffeoyl O-methyltyramine is isolated from Cuscuta reflexa with strong inhibitory activity against α-glucosidase with IC50 of 103.58 μM.		Glucosidase
TN6784	Ethyl rosmarinate	Methyl rosmarinate	MMP , Tyrosinase , Glucosidase
	Methyl rosmarinate (Methyl rosmarinate) inhibit the activity of tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1).		MMP , Tyrosinase , Glucosidase
TN1451	Brevifolincarboxylic acid		AhR , Aryl Hydrocarbon Receptor , Glucosidase
	Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarboxylic acid is an α-glucosidase inhibitor with an IC50 of 3...		AhR , Aryl Hydrocarbon Receptor , Glucosidase
T8260	4',5-Dihydroxyflavone		Lipoxygenase , Glucosidase
	4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).		Lipoxygenase , Glucosidase
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside		Others
	Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside		Others
	Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TQ0308	Castanospermine	1,6,7,8-Tetrahydroxyoctahydroindolizine,(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyindolizidine	Glucosidase
	Castanospermine (1,6,7,8-Tetrahydroxyoctahydroindolizine) is a natural compound that inhibits α- and β-glucosidases, especially glucosidase l.		Glucosidase
T3S2072	3-Butylidenephthalide	Butylidene phthalide,n-Butylidenephthalide	Parasite , Glucosidase
	1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitiv...		Parasite , Glucosidase
TN2302	Viscidulin III	Ganhuangenin	Glucosidase
	Viscidulin III (Ganhuangenin) is present in Scutellaria baicalensis and acts as an α-glucosidase inhibitor.		Glucosidase
TN1705	Glycyrrhisoflavone		MAO , Tyrosinase , NO Synthase , Immunology/Inflammation related
	Glycyrrhisoflavone is a tyrosinase inhibitor with anti-inflammatory effects. Glycyrrhisoflavone inhibits α-glucosidase and monoamine oxidase.
T6S2122	Ginkgolic Acid (C13:0)	6-Tridecylsalicylic acid,Ginkgolic acid (13:0),Ginkgoneolic Acid,Ginkgolic acid C13:0	Antibacterial , Glucosidase
	Ginkgolic Acid (C13:0) (6-Tridecylsalicylic acid): 0exhibits the highest α-glucosidase inhibitory activity.		Antibacterial , Glucosidase
TN7134	Magnoloside B		Glucosidase
	Magnoloside B, a phenylethanol glycoside from the fruit of Magnolia officinalis, is an α-glucosidase inhibitor with protective effects against free radical-induced oxidative damage and can be used in cancer research.		Glucosidase
T13130	Terphenyllin		Glucosidase
	Terphenyllin has α-glucosidase inhibitory activity, and is a natural product isolated from the coral derived fungus Aspergillus candidus.		Glucosidase
T8202	Kaempferol 3-O-gentiobioside	Kaempferol 3-gentiobioside	Glucosidase
	Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).		Glucosidase
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
T6S0535	Pinoresinol diglucoside	Pinoresinol Diglucopyranoside	Glucosidase
	1. Pinoresinol diglucoside (Pinoresinol Diglucopyranoside) is a putative α-glucosidase inhibiting compound. 2. Pinoresinol diglucoside is a important antihypertensive compound.		Glucosidase
T5690	7,4'-Di-O-methylapigenin	4',7-DIMETHOXY-5-HYDROXYFLAVONE	Amylase
	7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines.		Amylase
T6S1371	Isovitexin	Homovitexin,Saponaretin,Apigenin-6-C-Glucoside	NF-κB , JNK , Glucosidase
	1. Isovitexin (Apigenin-6-C-Glucoside) exhibits a potential antioxidant activity. 2. Isovitexin shows a strong antihyperglycemic action, inhibits α-glucosidase in vivo.		NF-κB , JNK , Glucosidase
TN1928	Methyl rosmarinate		MMP , Anti-infection , Tyrosinase
	Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has...		MMP , Anti-infection , Tyrosinase
TN2130	Manghaslin	Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside	AChE , Glucosidase
	Manghaslin (Quercetin 3-O-rutinoside-(1->2)-O-rhamnoside) has considerable α-glucosidase inhibitory activity, illustrating the anti-diabetic potential of phenolic-rich litchi pulp extracts. Manghaslin also shows inhibito...		AChE , Glucosidase
TN4368	Kaempferol-3,7-di-O-β-glucoside	Kaempferol 3,7-di-O-glucoside	Glucosidase , Amylase
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...		Glucosidase , Amylase
T41044	Naringinase		Glucosidase
	Naringinase is a hydrolytic enzymatic complex that exhibits α-L-rhamnosidase and β-D-glucosidase activities. It is widely found in nature and is primarily utilized for the biotransformation of steroids, antibiotics, and ...		Glucosidase
T0247	Acarbose	BAY g 5421	Glucosidase
	Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.		Glucosidase
T2S0731	Trilobatin	P-Phlorizin	Amylase
	Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...		Amylase
T21344	1-Deoxynojirimycin hydrochloride	Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K , Antibacterial , Antibiotic , Glucosidase
	1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.		PI3K , Antibacterial , Antibiotic , Glucosidase
TN3500	Beta-Amyrone	β-Amyron	COX , AChR , PPAR , Antifection
	beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...		COX , AChR , PPAR , Antifection
T41095	(E)-3-(4-Methoxyphenyl)acrylic acid		Glucosidase
	(E)-3-(4-Methoxyphenyl)acrylic acid is a small molecule compound isolated from the rhizome of Etlingera pavieana (Pierre ex Gagnep.) R. M. Sm. It is a novel α-glucosidase inhibitor. (E)-3-(4-Methoxyphenyl)acrylic acid ha...		Glucosidase
T3S0860	Gitogenin		UGT
	1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5α-furastan-3β, 22, 26-triol are the inhibitors of e...		UGT
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
TN1956	Mulberrofuran G		Phosphatase , HBV , Glucosidase
	Mulberrofuran G, isolated from Morus alba L., has anti-hepatitis B virus activity and protects against ischemic injury-induced cell death. Mulberrofuran G is a dual inhibitor of PTP1B and alpha-glucosidase for use in the...		Phosphatase , HBV , Glucosidase
T3851	Vicenin 2	Vicenin -2	RAAS
	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,...		RAAS
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
T3S1612	Kuwanon G	Moracenin B,Kuwanone G	Phosphatase , Antibacterial , Bombesin Receptor , AChR , AChE , Glucosidase
	1. Kuwanon G (Moracenin B) as dual inhibitors of PTP1B and α-glucosidase enzymes, as well as insulin sensitizers, it may potentially be utilized as an effective treatment for Type II diabetes mellitus. 2. Kuwanon G has a...
T7028	Licochalcone C	LICOCHALCONEC	Phosphatase , Antioxidant , Glucosidase
	Licochalcone C (LICOCHALCONEC) has potent antioxidant properties and inhibition of bacterial growth and cellular respiration. It has cardioprotection effect, via antioxidant, anti-inflammatory, and anti-apoptotic activit...		Phosphatase , Antioxidant , Glucosidase
T11686	Isotanshinone I		GABA Receptor
	Isotanshinone I with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively. Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE,		GABA Receptor
TN6600	Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside		HIV Protease
	Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is a glucopyranoside that inhibits HIV-2 RNase H with an IC50 of 5.19 μM.		HIV Protease
T41025	Prunetin 5-O-β-D-glucopyranoside
	Prunetin 5-O-β-D-glucopyranoside, an isoflavone obtained from Potentilla astracanica extracts, is a potent uncompetitive inhibitor of α-glucosidase (IC 50 = 56.05 μg/mL). It serves as a valuable tool for type-2 diabetes ...
T38587	Chrysophanol triglucoside
	Chrysophanol triglucoside, an anthraquinone derivative obtained from Cassia obtusifolia, demonstrates inhibitory activity against protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase, with half-maximal inhibitory c...
T3838	Quercetin 3,7-dimethyl ether	3,7-Di-O-methylquercetin	Others
	3,7-Di-O-methylquercetin shows α-glucosidase inhibition.		Others
TN6454	Parvisoflavanone
	Parvisoflavanone may have α-Glucosidase inhibitory activity.
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