α-msh — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7813	α-MSH	MSH, amide,CZEN-002,α-Melanocyte-Stimulating Hormone (MSH), amide	Melanocortin Receptor , Adenylyl cyclase
	α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.		Melanocortin Receptor , Adenylyl cyclase
T35406	α-MSH TFA
	α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocyt...
TP1097	Melanotan I	[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I	Others
	Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as...		Others
T8566	AA92593		Others
	AA92593 has been used as a selective inhibitor of melanopsin.		Others
T76340	(Nle4)-α-MSH
	(Nle4)-α-MSH, a synthetic analogue of the melanocyte-stimulating hormone α-MSH, exhibits the capability to reversibly darken frog skin. Additionally, it demonstrates sustained activity following exposure to heat and alka...
T76346	(D-Phe7)-α-MSH
	(D-Phe7)-α-MSH is an α-MSH analogue [1] .
T7589	Afamelanotide acetate	afamelanotide	Melanocortin Receptor
	Afamelanotide acetate is a synthetic α-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria.		Melanocortin Receptor
T83188	Acetyl-α-MSH (11-13)
	Acetyl-α-MSH (11-13), the acetylated C-terminal tripeptide of α-MSH, exhibits antipyretic and anti-inflammatory effects [1] [2].
T76347	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
	Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effect in rat models [1] [2].
TP1101	Nonapeptide-1 acetate salt (158563-45-2 free base)	Melanostatine-5 acetate salt,Nonapeptide-1 acetate salt	Melanocortin Receptor
	Nonapeptide-1 acetate salt (158563-45-2 free base) (Melanostatine-5 acetate salt) , a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Nonapeptide-1 acetate salt (1...		Melanocortin Receptor
TP1245L	ACTH 4-11 acetate	ACTH 4-11 acetate (67224-41-3 Free base)	Others
	ACTH 4-11 acetate is an adrenocorticotropin hormone fragment and possesses the same amino acid sequence as α-melanocyte stimulating hormone (MSH) does. ACTH 4-11 acetate exhibits a weak MSH potency only at high doses (10...		Others
TP2212L	A-MSH, amide Acetate(581-05-5 free base)		Melanocortin Receptor
	a-MSH, amide Acetate as an endogenous neuropeptide. It is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelano...		Melanocortin Receptor
TP1324	Melanotan (MT)-II		Melanocortin Receptor
	Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).		Melanocortin Receptor
TP1244L1	Adrenocorticotropic Hormone (ACTH) (1-10), human acetate	Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base)	Others
	Adrenocorticotropic Hormone (ACTH) (1-10), human acetate is a fragment of adrenocorticotropin hormone. Adrenocorticotropic Hormone (ACTH) (1-10), human acetate possesses a weak α-MSH potency only at 100 and 1000 nM.		Others
T20501	Undecylenoyl phenylalanine	Undecylenoylphenylalanine,Sepiwhite msh QD,Sepiwhite msh	Melanocortin Receptor
	Undecylenoyl phenylalanine (Sepiwhite msh QD) is a novel depigmenting agent, which possibly acts as an alpha-melanocyte-stimulating hormone antagonist, thus inhibiting melaninogenesis.		Melanocortin Receptor
TP1898	HS024	HS 024	Melanocortin Receptor
	HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-...		Melanocortin Receptor
T7608	Bremelanotide Acetate	bremelanotide,PT-141 Acetate	Melanocortin Receptor
	Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) .		Melanocortin Receptor
T5464	JNJ-10229570	JNJ10229570,UNII-N9IX402L35,JNJ 10229570	Melanocortin Receptor
	JNJ-10229570 (UNII-N9IX402L35) is an antagonist of melanocortin receptor 1 (MC1R) and melanocortin receptor 5 (MC5R), which inhibits sebaceous gland differentiation and the production of sebum-specific lipids.		Melanocortin Receptor
T68328	Modimelanotide
	Modimelanotide is a melanocortinergic peptide drug derived from α-melanocyte-stimulating hormone (α-MSH) which was under development for the treatment of acute kidney injury. It acts as a non-selective melanocortin recep...
TP1244	Adrenocorticotropic Hormone (ACTH) (1-10), human	ACTH (1-10), human
	Adrenocorticotropic Hormone (ACTH) (1-10), human is a fragment of the adrenocorticotropin hormone. It exhibits a weak potency of α-melanocyte stimulating hormone (α-MSH), but only at high doses (100 and 1000 nM).
TP2212	A-MSH, amide		Others
	a-MSH, amide is a peptide with the sequence Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, MW= 1664.9. The melanocyte-stimulating hormones (collectively referred to as MSH or intermedins) are a class of pept...		Others
T80207	Tetrapeptide		DNA/RNA Synthesis
	Tetrapeptide, an α-MSH analogue, stimulates melanin production and mitigates DNA damage by attenuating reactive oxidative species generation and augmenting DNA photoproduct repair [1].		DNA/RNA Synthesis
T76303	(p-Iodo-Phe7)-ACTH (4-10)
	(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist. It effectively inhibits α-melanocyte-stimulat...
T76642	Acetyl-ACTH (2-24) (human, bovine, rat)
	Acetyl-ACTH (2-24) (human, bovine, rat), a proopiomelanocortin (POMC) peptide fragment, includes adrenocorticotrophin (ACTH) precursor of α-MSH and acts as an agonist at the MC-1 receptor [1].
T76644	Acetyl-ACTH (4-24) (human, bovine, rat)
	Acetyl-ACTH (4-24) (human, bovine, rat), a proopiomelanocortin (POMC) peptide fragment, functions as an agonist at the MC-1 receptor [1]. This compound encompasses a sequence present in adrenocorticotrophin (ACTH), which...
T76072	CCZ01048
	CCZ01048, an analogue of α-melanocyte-stimulating hormone (α-MSH), demonstrates a high binding affinity for the melanocortin 1 receptor (MC1R), with a Ki of 0.31 nM. It rapidly internalizes into B16F10 melanoma cells and...
T76643	Acetyl-ACTH (3-24) (human, bovine, rat)
	Acetyl-ACTH (3-24) (human, bovine, rat) is a segment derived from the proopiomelanocortin (POMC) peptide, functioning as an agonist at the MC-1 receptor [1]. This compound encompasses adrenocorticotrophin (ACTH), a precu...
TP2011	JKC363	JKC 363
	Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, atten...
T75850	JKC363 TFA
	JKC363 TFA is a selective melanocortin MC4 receptor antagonist that exhibits a 90-fold higher affinity for the MC4 receptor (IC50=0.5 nM) compared to the MC3 receptor (44.9 nM). This compound effectively inhibits the α-M...
T76072L	CCZ01048 TFA
	CCZ01048 TFA, an α-MSH analogue, demonstrates a strong binding affinity for the melanocortin 1 receptor (MC1R), displaying a K i value of 0.31 nM. It exhibits rapid internalization into B16F10 melanoma cells and maintain...
T75715	Nonapeptide-1 acetate salt
	Nonapeptide-1 (Melanostatine-5) acetate salt, a peptide hormone, functions as a selective and competitive antagonist of the melanocortin 1 receptor (MC1R) with a binding affinity (K i) of 40 nM. It effectively inhibits α...
T35460	β-Endorphin (rat)
	β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. It is produced via piomelanocortin cleavage in the pituitary gland, hypothalamus, and in lymphocytes, then migrates to its sites...

Compounds

α-MSH

T7813

Synonym: MSH, amide,CZEN-002,α-Melanocyte-Stimulating Hormone (MSH), amide

Target: Melanocortin Receptor, Adenylyl cyclase

Synonym: [Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I

Afamelanotide acetate

T7589

Synonym: afamelanotide

Target: Melanocortin Receptor

Acetyl-α-MSH (11-13)

T83188

Synonym:

Target:

Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2

T76347

Synonym:

Target:

Nonapeptide-1 acetate salt (158563-45-2 free base)

TP1101

Synonym: Melanostatine-5 acetate salt,Nonapeptide-1 acetate salt

Target: Melanocortin Receptor

ACTH 4-11 acetate

TP1245L

Synonym: ACTH 4-11 acetate (67224-41-3 Free base)

Target: Others

a-MSH, amide Acetate(581-05-5 free base)

TP2212L

Synonym:

Target: Melanocortin Receptor

Melanotan (MT)-II

TP1324

Synonym:

Target: Melanocortin Receptor

Adrenocorticotropic Hormone (ACTH) (1-10), human acetate

TP1244L1

Synonym: Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base)

Target: Others

Undecylenoyl phenylalanine

T20501

Synonym: Undecylenoylphenylalanine,Sepiwhite msh QD,Sepiwhite msh

Target: Melanocortin Receptor

HS024

TP1898

Synonym: HS 024

Target: Melanocortin Receptor

Bremelanotide Acetate

T7608

Synonym: bremelanotide,PT-141 Acetate

Target: Melanocortin Receptor

JNJ-10229570

T5464

Synonym: JNJ10229570,UNII-N9IX402L35,JNJ 10229570

Target: Melanocortin Receptor

Adrenocorticotropic Hormone (ACTH) (1-10), human

TP1244

Synonym: ACTH (1-10), human

Target: DNA/RNA Synthesis

(p-Iodo-Phe7)-ACTH (4-10)

T76303

Synonym:

Target:

Acetyl-ACTH (2-24) (human, bovine, rat)

T76642

Synonym:

Target:

Acetyl-ACTH (4-24) (human, bovine, rat)

Acetyl-ACTH (3-24) (human, bovine, rat)

Nonapeptide-1 acetate salt

Cat No.	Product Name	Targets
T2S0799	Noroxyhydrastinine	Tyrosinase
	Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 ...	Tyrosinase
TN3723	Cryptomeridiol	PAFR , Antifection
	Cryptomeridiol is a potential skin-whitening agent, exhibits melanogenesis inhibitory activity on α-MSH-stimulated B16 melanoma cells. Cryptomeridiol has low activity against A. niger, T. mentagrophytes, and C. albicans....	PAFR , Antifection

Search Result

Targets

Compounds

Natural Products

Compounds

Natural Products