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rebamipide

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  • Inhibitors & Agonists
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Rebamipide
Proamipide, OPC12759
T156290098-04-7
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.
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Rebamipide-d4
OPC12759 D4,Rebamipide D4,Proamipide D4
T195471219409-06-9
Rebamipide D4 is deuterium labeled Rebamipide.
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7-10 days
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Rebamipide mofetil
T94721527495-76-6
Rebamipide mofetil, an orally active prodrug of Rebamipide, functions as a mucoprotective agent.
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