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Cat No. | Product Name | Synonyms | Targets |
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T41175 | OB 24 hydrochloride | ||
OB 24 hydrochloride is a potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in adv... | |||
T28224 | OB-2 | ||
OB-2 is an inhibitor of stomatin-like protein-3 (STOML3) oligomerization. OB-2 reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in vivo. | |||
T68288 | OB-24 free base | ||
OB-24 free base is a potent and selective heme oxygenase 1 (HO-1) inhibitor. | |||
T28223 | OB-1 | ||
OB-1 is an inhibitor of stomatin-like protein-3 (STOML3) oligomerization. OB-1 reversibly reduces the sensitivity of mechanically gated currents in sensory neurons and silence mechanoreceptors in vivo. | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T6832 | Fatostatin hydrobromide | Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin | NPC1L1 , Fatty Acid Synthase |
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. | |||
T71294 | BMS-763534 | ||
BMS-763534 is a potent antagonist of corticotropin-releasing factor/hormone receptor 1 (CRHR-1). | |||
T31752 | FD&C Yellow No. 4 | NSC-11234,NSC11234,Yellow OB,NSC 11234 | |
FD&C Yellow No. 4 is a dye. | |||
T3312 | AM-2394 | AM2394 | Glucokinase |
AM-2394 is an effective and specific Glucokinase agonist (GKA, EC50: 60 nM), which catalyzes the phosphorylation of glucose to glucose-6-phosphate. AM-2394(AM2394) increases the affinity of GK for glucose by approximatel... | |||
T23557 | Talibegron hydrochloride | ZD2079 hydrochloride,ZD 2079 | Adrenergic Receptor |
Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. In... | |||
T70509 | INU-101 | ||
INU-101 is an 11β-HSD1 inhibitor. In KKAy mice, ob/ob mice, and ZDF rats, oral administration of INU-101 led to enhanced insulin sensitivity and the lowering of the fasting level of glucose in the blood. INU-101 therefor... | |||
T27239 | Edaglitazone | Edaglitazone sodium,BM-13.1258,RO-2052349-602,R-483,RO-2052349-000 | |
Edaglitazone is a PPARγ agonist. Edarglitazone restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. | |||
TP2020 | [Pro3]-GIP (Mouse) | ||
GIP receptor antagonist (IC50 = 2.6μM). Inhibits GIP-stimulated insulin release from pancreatic β cells in vitro. In ob/ob mice, blocks the effects of GIP on insulin release and plasma glucose levels. Also improves intra... | |||
T83696 | Gastric Inhibitory Peptide 1 (3-42) (human) TFA | Glucose-dependent Insulinotropic Polypeptide 3-42,GIP-1 (3-42) | |
Gastric inhibitory peptide 1 (GIP-1) (3-42), a fragment of the incretin hormone GIP and antagonist to the GIP receptor, is generated through the action of serum dipeptidyl peptidase 4 (DDP-4). When administered at 25 nmo... | |||
T71296 | 4-Aaqb | ||
4-Aaqb, also known as OB-318, is a natural inhibitor of the autophagy pathway, enhancing immune function, suppressing MAPK and NFκB, showing anti-inflammatory, hypoglycemic, vasorelaxative, and antiproliferative activiti... | |||
TP1356 | Leptin (22-56), human | ||
Leptin(22-56),human is a peptide fragment of Leptin, which ACTS through a variety of subtypes of Ob-Rs. | |||
T16507 | PF-5006739 | Casein Kinase | |
PF-5006739 is an effective and selective inhibitor of CK1δ/ε (IC50s: 3.9 nM and 17.0 nM, respectively). PF-5006739 is a potential therapeutic agent for a range of psychiatric disorders with low nanomolar in vitro potency... | |||
T69603 | BR103354 | ||
BR103354 is a novel fibroblast activation protein (FAP) inhibitor with anti-diabetic and anti-steatotic effects. BR103354 inhibited FAP with an IC50 value of 14 nM, showing high selectivity against dipeptidyl peptidase (... |
Cat No. | Product Name | Species | Expression System |
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TMPY-00875 | Leptin Protein, Human, Recombinant | Human | E. coli |
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu... | |||
TMPY-01725 | Leptin Receptor Protein, Human, Recombinant (His) | Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe... | |||
TMPY-06375 | Leptin Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 |
Leptin is one of the most important hormones secreted by adipocytes, as an adipokine that modulates multiple functions including energy homeostasis, thermoregulation, bone metabolism, endocrine, and pro-inflammatory immu... | |||
TMPK-00587 | CDH11 Protein, Human, Recombinant (aa 54-617, His) | Human | HEK293 |
CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was... | |||
TMPJ-00977 | LEPR Protein, Mouse, Recombinant (mFc) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00975 | LEPR Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00976 | LEPR Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPJ-00411 | LEPR Protein, Human, Recombinant (hFc) | Human | Human Cells |
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta... | |||
TMPK-00050 | Leptin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita... | |||
TMPJ-00606 | Leptin Protein, Carassius auratus, Recombinant (His) | Carassius auratus | Yeast |
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin ... | |||
TMPJ-00052 | Leptin Protein, Mouse, Recombinant | Mouse | E. coli |
Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have ... | |||
TMPJ-01267 | CDH11 Protein, Human, Recombinant (His) | Human | Human Cells |
Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in... | |||
TMPY-00874 | Leptin Receptor Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Leptin Receptor or CD295 belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-spe... | |||
TMPK-00718 | Siglec-5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by va... | |||
TMPK-00720 | Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated | Human | HEK293 |
Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory rece... | |||
TMPK-00719 | Siglec-5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by va... | |||
TMPY-02884 | Siglec-5 Protein, Human, Recombinant (hFc) | Human | HEK293 |
SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIG... | |||
TMPK-00729 | Siglec-6 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by ... | |||
TMPY-03549 | Siglec-5 Protein, Human, Recombinant | Human | HEK293 |
SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIG... | |||
TMPJ-00669 | Siglec-5 Protein, Human, Recombinant (His & Flag & hFc) | Human | Human Cells |
Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type do... | |||
TMPJ-00516 | OBhFc1 Protein, Human, Recombinant (His) | Human | E. coli |
CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA ... |