iia

Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF/VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease.

Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.

11-Oxomogroside IIa is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. It has inhibitory effects against the EBV-EA activation induced by TPA, shows weak inhibitory effects on activation of NOR 1, a nitric oxide (NO) donor.

Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite.

1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.

Enacyloxin IIa (ENX IIa) is a polyene antibiotic with activity against both Gram-positive and Gram-negative bacteria, while exhibiting weak antifungal properties and no effect on yeast.

Escin IIA, a naturally derived saponin isolated from the seeds of horse chestnut (Aesculus hippocastanum L.), has been shown to exert beneficial effects in acute inflammatory conditions in animal models. Escin IIA additionally demonstrates gastroprotective effects by reducing ethanol-induced gastric mucosal lesions in rats, thereby supporting its role in the study of anti-inflammatory and gastroprotective mechanisms in preclinical research.

Cinchonain IIa has antioxidant activity, it shows high radical scavenging activity and reducing power.

Hydroxytanshinone ⅡA has good antiproliferative effect on SGC-7901,HeLa, and HepG 2 cell, the values of IC50 are 4.18, 6.08 and10.20 uM, respectively; it has tumor cell proliferation inhibition significantly stronger than the tanshinoneⅡA.

11-Oxomogroside IIA2 is a natural product for research related to life sciences. The catalog number is TN6624 and the CAS number is 2170761-37-0.

Mogroside IIA1 (Mogroside II-A1) is isolated from the fruits of Siraitia grosvenorii. Mogroside IIA1 is a a nonsugar sweetener and sweeter than sucrose. Mogroside IIA1 possesses antioxidant, antidiabetic and anticancer activities.

Cucurbitacin IIa 2-O-glucoside is a natural product for research related to life sciences. The catalog number is TN5995 and the CAS number is 77704-34-8.

Virginiamycin M1 (Pristinamycin IIA) is a macrocyclic lactone peptide antibiotic and is a member of the streptogramin A group of antibiotics.

1,2-Didehydrotanshinone IIA is a useful organic compound for research related to life sciences and the catalog number is T126245.

Tanshinone IIA anhydride is a potent, irreversible inhibitor of human carboxylesterase (CE), exhibiting inhibitory constants (K i values) of 1.9 nM for human CE1 and 1.4 nM for human intestinal CE (hiCE), respectively [1].

1-Oxotanshinone IIA (Compound 6), derived from Perovskia artemisioides, exhibits potent anti-inflammatory activity [1].

Tanshinone IIA (Standard) is a reference standard for research and analysis in studies involving Tanshinone IIA. Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF/VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease.

Cucurbitacin IIA (Standard) is a reference standard for research and analysis in studies involving Cucurbitacin IIA. 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.

Mycolic acid IIa is a structural lipid component of the Mycobacterium cell wall. It can be isolated from Mycobacterium bovis BCG and plays a significant role in regulating membrane permeability and stability, making it a potential focus for tuberculosis (TB) infection research.

Hemslecin D is a natural product for research related to life sciences. The catalog number is TN5989 and the CAS number is 586960-44-3.

3alpha-Hydroxytanshinone IIA is a useful organic compound for research related to life sciences and the catalog number is T123833.

Momordin IIa is a useful organic compound for research related to life sciences and the catalog number is T123849.

Sulfotanshinone IIA Sodium mitigates oxidative damage in peritoneal mesothelial cells caused by peritoneal dialysis solution (PDS) by inhibiting the ASK1-p38 signaling pathway.

3α-Hydroxytanshinone IIA (Compound 5), an isolatable compound from the roots of Salvia miltiorrhiza [1], exhibits specific characteristics.