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Search Results for " hce "

Targets

4

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T82232 hCES2A-IN-1
hCES2A-IN-1 (compound 20w), a potent hCES2A inhibitor derived from bysspectin A, exhibits an IC50 value of 1.6 nM, demonstrating an approximately 1000-fold potency enhancement compared to its lead compound, bysspectin A ...
T82231 hCES2-IN-1
hCES2-IN-1 (Compound 24) is a reversible, selective inhibitor of the human carboxylesterase 2 (hCES2) enzyme, exhibiting an IC50 of 6.72 μM. This compound diminishes hCES2 levels in vivo and demonstrates efficacy in alle...
T17028 Tefinostat CHR-2845 HDAC
Tefinostat (CHR-2845) is a potent monocyte/macrophage-targeted histone deacetylase (HDAC) inhibitor. Tefinostat is cleaved to the active acid CHR-2847 by the intracellular esterase human carboxylesterase-1 (hCE-1).Tefino...
T35549 Elsinochrome A
Elsinochrome A is a perylenequinone fungal metabolite that has been found inHypomycesand has anticancer activity.1Photoactivation of elsinochrome A induces the production of singlet oxygen and apoptosis in R366.4 rhesus ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06754 CES1 Protein, Human, Recombinant (His) Human HEK293
CES1 encodes carboxylesterase-1, an important drug-metabolizing enzyme with high expression in the liver. Variants generated by the exchange of segments with CES1P1 complicate the genotyping of CES1. CES1 is involved in ...
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