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(2)
By Target- Serine/threonin kinase
- Apoptosis(1)
- PDK(1)
- Wnt/beta-catenin(1)
- Others(1)
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Results for "
crt 5
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- CRT5T217951034297-58-9CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. It inhibits VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB (cAMP-response-element-binding protein), and HSP27 (heat-shock protein 27) at Ser82. Additionally, CRT5 decreases VEGF-induced endothelial migration, proliferation, and tubulogenesis[1].
- $78
SizeQTY - iCRT-5iCRT5, iCRT 5T2758218623-44-4iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity, blocking Wnt/β-catenin expression and inducing apoptosis. iCRT-5 can be used in the study of multiple myeloma.
- $41
SizeQTY
- PKD-IN-1 dihydrochloride (956121-30-5 free base)T8957L2308510-39-4PKD-IN-1 dihydrochloride is an inhibitor of PKD.
- $30
SizeQTY
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