antimycobacterial agent-4

Antimycobacterial agent-4 (4-nitro-N-[4-(2-pyridyl)thiazol-2-yl]benzamide) has antibacterial activity against Mycobacterium tuberculosis.

Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole antimycobacterial agent with a minimum inhibitory concentration (MIC) of 2 μg/mL. It inhibits Mtb KatG and induces the accumulation of reactive oxygen species (ROS) within Mtb cells, leading to oxidative damage and ultimately causing Mtb cell death.

Antimycobacterial agent-12 (Compound Ec42) is a Platensimycin derivative and acts as a dual inhibitor of KasA and KasB. It demonstrates minimum inhibitory concentrations (MIC) of 2 μg/mL against Staphylococcus aureus ATCC 29213, 2 μg/mL against Mycobacterium smegmatis, and 4 μg/mL against its isoniazid-resistant strains. In a Mycobacterium smegmatis-infected mouse model, Antimycobacterial agent-12 exhibits excellent antimycobacterial activity, making it a valuable tool for tuberculosis research.

Anti-infective agent 3 is an antiprotozoal and antimycobacterial agent. Anti-infective agent 3 (compound 3l) exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 exhibits antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL [1].

1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effect

Pyrazinamide-D3 is a deuterated compound of Pyrazinamide. Pyrazinamide (T1426) has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.

8-Gingerol (Standard) is a reference standard for research and analysis in studies involving 8-Gingerol. 1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristics. 5. 8-Gingerol seems to be effective in an animal model of rheumatoid arthritis. 6. 8-Gingerol inhibits the anti-serotonin 3 receptor function, exhibits cardiotonic activity. 7. 8-Gingerol affects gastric motility and potentially have an antispasmodic effect on the gastrointestinal system. 8. 8-gingerol inhibited melanogenesis in B16F1 and B16F1 cells by down-regulation of both mitogen-activated protein kinases (MAPK) and protein kinase A (PKA) signaling pathways or through its antioxidant properties.

Pyrazinamide-D3 (Standard) is a reference standard of Pyrazinamide-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.