a-779

A 779 is a potent antagonist of the G-protein-coupled receptor Mas, the Ang1-7 receptor, which is distinct from conventional AngII.

A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.

TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).

Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.

Temsirolimus (CCI-779) is a specific mTOR inhibitor ( IC50: 1.76 μM), used in the treatment of advanced renal cell cancer.

CRBN ligand-779 is an E3 ubiquitin ligase cereblon (CRBN) ligand that is utilized for recruiting cereblon proteins. CRBN ligand-779 can be linked to a target protein ligand via a linker to form a PROTAC.

Anti-CD33 Antibody (IMGN-779 Naked Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.