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a 3 hydrochloride

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    259
    TargetMol | Inhibitors_Agonists
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A-3 hydrochloride
T1406978957-85-4
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM).
  • $30
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ATB107 hydrochloride
ATB107 hydrochloride(455325-51-6 Free base)
T10394L In house
ATB107 hydrochloride is a novel and potent inhibitor of indole-3-glycerol phosphate synthase (IGPS) with a KD of 3 μM.
  • $41
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CSRM617 hydrochloride
CSRM617 hydrochloride(787504-88-5 Free base)
T10896L1353749-74-2In house
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor), with a Kd of 7.43 µM in SPR assays, directly binding to the OC2-HOX domain. CSRM617 hydrochloride induces apoptosis through the appearance of cleaved Caspase-3 and PARP and is well tolerated in the mouse model of prostate cancer [1].
  • $35
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Anticonvulsant agent 10 HCl
T39252L1818253-48-3In house
5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride is a cyclopropanoid enzyme compound that acts as a lysine-specific demethylase-1 inhibitor for schizophrenia, developmental disorders, and neurodegenerative diseases.
  • $195
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N-0500 HCl
(-)-Propyl-9-hydroxynaphthoxazine Hydrochloride
T60107100935-99-7In house
N-0500 HCl ((-)-Propyl-9-hydroxynaphthoxazine Hydrochloride) is a very potent centrally acting DA receptor agonist. N-0500 HCl is a potent displacer of the specific [3H]DP-5,6-ADTN binding with IC50 of 3 nM.
  • $30
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Benzoquinamide hydrochloride
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride
T9881113-69-9In house
Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the increased peripheral vascular resistance.
  • $75
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2-AMinoMethyl-3-fluoropyridine hydrochloride
Fr213010312904-49-7
2-AMinoMethyl-3-fluoropyridine hydrochloride, with CAS No. 312904-49-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-AMinoMethyl-3-fluoropyridine hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
  • $35
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TargetMol | Inhibitor Sale
Methyl 2-aMino-2-(4-fluorophenyl)acetate hydrochloride
Fr21307342718-18-3
Methyl 2-aMino-2-(4-fluorophenyl)acetate hydrochloride, with CAS No. 42718-18-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 2-aMino-2-(4-fluorophenyl)acetate hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
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1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE
PDK034871985-80-3
1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE, with CAS No. 71985-80-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-METHYLPIPERIDINE-4-CARBOXYLIC ACID HYDROCHLORIDE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
  • $35
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Clomipramine hydrochloride
Clomipramine HCl, Anafranil
T025517321-77-6
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
  • $30
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Atomoxetine hydrochloride
Tomoxetine hydrochloride, LY 139603 HCl, Atomoxetine HCl, (R)-Tomoxetine hydrochloride
T086982248-59-7
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.
  • $40
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Granisetron hydrochloride
Granisetron HCl, BRL 43694A
T1042107007-99-8
Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.
  • $42
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Prazosin hydrochloride
Vasoflex, Prazosin hydrochloride, Prazosin HCl, Peripress, Minipress, cp-12299-1
T105019237-84-4
Prazosin hydrochloride (Vasoflex) reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not completely known. Prazosin hydrochloride is a synthetic piperazine derivative with hypotensive antiadrenergic properties, It is used in the treatment of heart failure, hypertension, pheochromocytoma, Raynaud's syndrome, prostatic hypertrophy, and urinary retention.
  • $30
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TargetMol | Citations Cited
Minocycline hydrochloride
Minocycline HCl
T110113614-98-7
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochloride can cause both an acute hepatitis-like syndrome occurring within 1 to 3 months of starting therapy or a more insidious chronic hepatitis with autoimmune features typically after long-term treatment.
  • $38
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Tropisetron hydrochloride
SDZ-ICS 930, Tropisetron HCl, ICS 205-930
T1173105826-92-4
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activities.
  • $48
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Rimonabant hydrochloride
SR 151716A, SR 141716A
T1519158681-13-1
Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity.
  • $38
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Naftifine hydrochloride
Naftin, Naftifungin, Naftifine HCl, Exoderil
T154365473-14-5
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its effect is unknown, it appears to selectively inhibit the enzyme squalene 2, 3-epoxidase, thereby inhibiting the biosynthesis of sterol. This results in a decreased amount of sterols, especially ergosterol which is the primary fungal membrane sterol, and a corresponding accumulation of squalene in fungal cells. Naftifine hydrochloride (Naftifine HCl) can be fungicidal as well as fungistatic to yeasts depending on the concentration and the organisms involved.
  • $35
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5-Methyltryptamine hydrochloride
α-helical CRF 9-41 acetate(90880-23-2 Free base), 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride
T198131010-95-3
5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.
  • $29
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Fingolimod hydrochloride
FTY720 HCl, Fingolimod (FTY720) HCl
T2539162359-56-0
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).
  • $35
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TargetMol | Citations Cited
3-Methoxytyramine hydrochloride
3-O-methyl Dopamine hydrochloride), 3-O-methyl Dopamine hydrochloride
T47101477-68-5
3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues; and in blood, cerebrospinal fluid (csf) or urine. Within a cell, 3-methoxytyramine is primarily located in the cytoplasm.
  • $29
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2,3-Diaminopropionic acid hydrochloride
3-Amino-L-alanine hydrochloride
T59781482-97-9
2,3-Diaminopropionic acid hydrochloride (3-Amino-L-alanine hydrochloride) is a competitive cystathionase(CTH) inhibitor.
  • $29
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2-Amino-3-mercaptopropanoic acid hydrochloride hydrate
DL-Cysteine hydrochloride monohydrate, DL-Cysteine hydrochloride hydrate
T64500116797-51-4
2-Amino-3-mercaptopropanoic acid hydrochloride hydrate is a cysteine derivative, widely used in biochemical experiments and drug synthesis research.
  • $30
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Regorafenib Hydrochloride
BAY73-4506 hydrochloride
T8402835621-07-3
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity
  • $30
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