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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13172L1 | TMP-778 | ROR | |
TMP-778 is a selective inverse agonist of RORγt. | |||
T3983 | TMP195 | TFMO 2,TMP 195 | HDAC |
TMP195 (TFMO 2) is a selective class IIa histone deacetylase (HDAC) inhibitor. | |||
T13174 | TMPyP4 tosylate | TMP 1363 | DNA/RNA Synthesis , Telomerase |
TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines. | |||
T31017 | Coumarin-TMP-Halo | Coumarin TMP Halo,CTH | |
Coumarin-TMP-Halo is a specific fluorescent protein labeling agent. | |||
T36126 | TMP-153 | ||
Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and choleste... | |||
T34893 | TMP-NVOC-Halo | TNH | |
TMP-NVOC-Halo is a caged protein labeling agent. | |||
T1857 | TMP269 | HDAC | |
TMP269 is an effective, specific class IIa HDAC inhibitor for HDAC4 (IC50: 157 nM), HDAC5 (IC50: 97 nM), HDAC7 (IC50: 43 nM), and HDAC9 (IC50: 23 nM), respectively. | |||
T78534 | NVOC cage-TMP-Halo | Others | |
NVOC cage-TMP-Halo is a photoactivatable, cell-permeable inducer of protein dimerization that enables rapid and reversible modulation of protein localization within living cells, with applications in dynamic cellular pro... | |||
T80972 | TNH | TMP-NVOC linker-Halo | |
TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1]. | |||
T24899 | Trimosulfa | Trimethoprim-sulfamethoxazole,Sulfamethoxazole-trimethoprim,TMP-SMX,Trimforte,Trimethoprimsulfa | |
Trimosulfa is a fixed antibiotic combination that widely used for mild-to-moderate bacterial infections and as prophylaxis against opportunistic infections. | |||
T83821 | Thymidine-5'-O-(α,β-methylene)diphosphate sodium | α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP | |
Thymidine-5’-O-(α,β-methylene)diphosphate (TMP-CP), a hydrolytically stable derivative of TDP, functions as an inhibitor of thymidine kinase (Ki = 23 µM). It serves as a precursor in the synthesis of α,β-methylene-2’-deo... | |||
T17108 | TMP920 | ROR | |
TMP920 inhibits RORγt binding to the SRC1 peptide (IC50: 0.03 μM). TMP920 is a highly potent and selective RORγt antagonist. | |||
T13172L | TMP778 | Others | |
TMP778 is an effective and selective RORγt inverse agonist (IC50: 7 nM in FRET assay). | |||
T13172 | TMP780 | ROR | |
TMP780 is an inverse RORγt agonist (IC50: 13 nM). RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders. | |||
T60080 | TMPH | 2,2,6,6-Tetramethylpiperidin-4-yl heptanoate | AChR |
TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders. | |||
T13173 | TMPA | Others , AMPK | |
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist. | |||
T40732 | TMPD dihydrochloride | ||
TMPD dihydrochloride is an active substrate of enzymatically convert redox and an electron donor for the reduction of heme peroxidases. | |||
T61796 | MtTMPK-IN-1 | ||
MtTMPK-IN-1 (compound 3) is a highly effective inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), exhibiting an IC50 value of 2.5 μM. It displays moderate to weak activity against Mtb H37Rv while demon... | |||
T61573 | MtTMPK-IN-5 | ||
MtTMPK-IN-5 (compound 17) is a highly effective inhibitor of M. tuberculosis thymidylate kinase (Mtb TMPK), demonstrating remarkable enzyme inhibitory activity with an IC50 value of 34 μM. Additionally, MtTMPK-IN-5 exhib... | |||
T61781 | MtTMPK-IN-6 | ||
MtTMPK-IN-6 (compound 1) is a highly effective inhibitor (IC 50 = 29 μM) of M. tuberculosis thymidylate kinase (Mtb TMPK). It is a valuable compound for tuberculosis research [1]. | |||
T35966 | Mn(III)TMPyP | ||
Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-... | |||
T27314 | Fe-TMPyP | ||
Fe-TMPyP binds to the prion protein PrP and inhibits misfolding. Fe-TMPyP is also a peroxynitrite decomposition catalyst. | |||
T63657 | MtTMPK-IN-9 | ||
MtTMPK-IN-9 is a moderately potent inhibitor of Mycobacterium thymidylate kinase (MtbTMPK) (IC50: 48 μM).MtTMPK-IN-9 has submicromolar activity against Mycobacterium but no significant cytotoxicity.MtTMPK-IN-9 can be use... | |||
T23462 | TMPH hydrochloride | Others | |
neuronal nicotinic ACh receptors (nAChRs) antagonist | |||
T63491 | MtTMPK-IN-8 | ||
MtTMPK-IN-8 is a moderately potent inhibitor of Mycobacterium thymidylate kinase (MtbTMPK) with no significant cytotoxicity, exhibiting submicromolar activity (MICs = 0.78-9.4 μM) against Mycobacterium and capable of bei... | |||
T28986 | TMPPAA | ||
TMPPAA is an allosteric agonist of 5-HT3 receptor. | |||
T63639 | MtTMPK-IN-7 | ||
MtTMPK-IN-7 is a moderately potent inhibitor of Mycobacterium brevis thymidylate kinase (MtbTMPK) (IC50: 47 μM).MtTMPK-IN-7 exhibits submicromolar activity against Mycobacterium brevis with MICs ranging from 2.3 to 4.7 μ... | |||
T62897 | MtTMPK-IN-3 | ||
MtTMPK-IN-3 (compound 25) is a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (MtTMPK) with an IC50 value of 0.12 μM. It also demonstrates inhibitory activity against Mtb H37Rv with a MIC of 12.5 μM an... | |||
T61780 | MtTMPK-IN-4 | ||
MtTMPK-IN-4 (compound 2), a para-piperidine, is a highly potent inhibitor of thymidylate kinase (MtTMPK) in Mycobacterium tuberculosis, exhibiting an IC50 value of 6.1 μM. Additionally, it possesses remarkable inhibitory... | |||
T78238 | 4′-DTMP | 4-Demethyltrimethoprim | DHFR , Antifungal |
4′-DTMP (4-Demethyltrimethoprim) is a potent DHFR inhibitor with antimicrobial activity that induces additional local interactions with the enzyme and inhibits Escherichia coli. | |||
T62305 | MtTMPK-IN-2 | ||
MtTMPK-IN-2 (compound 15), a potent inhibitor of Mycobacterium tuberculosis thymidylate kinase (Mt TMPK), demonstrates an IC50 value of 1.1 μM. This compound effectively inhibits Mtb H37Rv with a minimum inhibitory conce... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4730 | Thymidine-5'-monophosphate disodium salt | Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT | Others , Endogenous Metabolite |
Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome frag... | |||
T4558 | Trioxsalen | Trimethylpsoralen,Trioxysalen,Trisoralen | DNA Alkylator/Crosslinker , DHFR |
Trioxsalen (Trioxysalen) is a furanocoumarin and a psoralen derivative, in conjunction with UV-A for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, wh... | |||
T7892 | ATMP | Others | |
ATMP is a phosphonic acid with chelating properties. It is an antiscalant. | |||
T0572 | Methyl 3,4,5-trimethoxybenzoate | Methyl gallate trimethyl ether,Methyl EudesMate,3,4,5-Trimethoxybenzoic acid methyl ester,Methyl tri-O-methylgallate,Trimethylgallic acid methyl ester | Others |
Methyl 3,4,5-trimethoxybenzoate (Methyl EudesMate) is the intermediate of antibacterial efficiency medicine trimethoprim. | |||
T83320 | 4'-Demethylpodophyllotoxone | ||
4'-Demethylpodophyllotoxone, an intermediate in the biotransformation pathway of Alternaria alternata S-f6, undergoes further modification with 4-(2,3,5,6-tetramethylpyrazine-1) (4-TMP). This modification yields a novel ... | |||
T75540 | Ipomoeassin F | ||
Ipomoeassin F, a selective and potent inhibitor of endoplasmic reticulum (ER) protein translocation, targets the Sec61 complex's pore-forming subunit (Sec61α) at the ER membrane. It inhibits the ER membrane translocation... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00499 | TMP21 Protein, Human, Recombinant (mFc) | Human | HEK293 |
TMED10 disrupts the complex formation between TGF-beta type I (also termed ALK5) and type II receptors (TbetaRII). Misexpression studies revealed that TMED10 attenuated TGF-beta-mediated signaling. A 20-amino acid-long r... | |||
TMPH-02236 | TMPRSS2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Cleaves the vWF multimers in plasma into smaller forms thereby controlling vWF-mediated platelet thrombus formation. | |||
TMPH-02238 | TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated | Human | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | |||
TMPH-02239 | TMPRSS4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. | |||
TMPY-04985 | TMPRSS11D Protein, Human, Recombinant (His) | Human | HEK293 |
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ... | |||
TMPY-04928 | TMPRSS11B Protein, Human, Recombinant (His) | Human | HEK293 |
TMPH-02235 | TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) | Human | in vitro E. coli expression system |
Ribosomal protein P0 is the functional equivalent of E.coli protein L10. | |||
TMPH-03643 | TmpB Protein, Treponema phagedenis, Recombinant (His & Myc) | Treponema phagedenis | E. coli |
TMPY-01041 | Compound TMPY-01041 | ||
TMPJ-00960 | TMPO Protein, Human, Recombinant (His) | Human | E. coli |
Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domai... | |||
TMPH-02234 | TMPRSS11A Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). | |||
TMPH-02237 | TMPRSS2 Protein, Human, Recombinant (His & Myc) | Human | HEK293 |
Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that shows proteolytic activity toward the hyale... | |||
TMPH-02945 | TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
TMPH-03291 | FABP3 Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 |
Tmp may serve as a porin or transport protein for large molecules. |