T7375

A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in

Farnesyl Pyrophosphate ammonium salt is an isomer of (E,E)-Farnesyl Pyrophosphate ammonium salt, which is a key metabolic intermediate in the mevalonate (MVA) pathway and an agonist of TRPM2, and is involved in cholesterol synthesis, ubiquinone synthesis, protein farnesylation and other physiological processes.

Lepirudin, a recombinant form of hirudin, serves as a potent, irreversible inhibitor of thrombin, showcasing its anticoagulant efficacy in heparin-induced thrombocytopenia (HIT) [1].

Glutarylcarnitine lithium, a key diagnostic metabolite for malonic aciduria and glutaric aciduria type I, is routinely monitored in the majority of newborn screening programs utilizing tandem mass spectrometry [1].

Pristanic acid is an endogenous branched-chain saturated fatty acid and a natural, specific ligand for peroxisome proliferator-activated receptor alpha (PPARα). Pristanic acid regulates the expression of genes related to fatty acid oxidation and lipid transport via the PPARα pathway and can be used in research on fatty liver disease and atherosclerosis.

Farnesyl pyrophosphate (Farnesyl diphosphate), a 15-carbon isoprenoid from the mevalonate (MVA) pathway, functions as a metabolic intermediary and TRPM2 (TRP Channel) agonist, facilitating TRPM2 channel opening and ion influx. It is crucial in synthesizing cholesterol, ubiquinones, and geranyl-geranyl pyrophosphate (GGPP), and in protein farnesylation decoration [1].

Pristanic acid is an endogenous branched fatty acid produced by α -oxidation of phytanic acid, which is further metabolized by β -oxidation in peroxisome. As a metabolite of fatty acids, Pristanic acid can be used as a ligand to activate PPARα, thus regulating the expression of genes related to lipid metabolism and energy homeostasis. Its metabolic abnormalities are related to a variety of peroxisome-related diseases, including Zellweger syndrome, α -methyl acyl-coenzyme A racemase deficiency, and infantile Refsum disease.

Glycolithocholic acid 3-sulfate (SLCG) is a bile acid derivative and metabolite of glycocholic acid, selectively inhibiting HIV-1 replication in vitro, used in the study of HIV infection.