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Search Result

Search Results for " sert "

155

Compounds

6

Natural Products

Cat No. Product Name Synonyms Targets
T28758 SERT inhibitor 69419
SERT inhibitor 69419 inhibits serotonin reuptake.
T73273 SERT-IN-2
SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant. It demonstrates a favorable bioavailability of 83.28% in rats and has the ability to cross the blood-brain barrier.
T72824 RAGE/SERT-IN-1
RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and 31.09 nM, respectively. It demonstrates a significant neurop...
T8708 Paroxetine Serotonin Transporter
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
T12232 Nitroxazepine CIBA 2330Go Serotonin Transporter
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T0450 Fluoxetine LY-110140 5-HT Receptor , Serotonin Transporter , MRP , Autophagy
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.
T22714 Decynium 22 Others
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor
T22453 Venlafaxine Wy 45030 Serotonin Transporter
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
T2594 Dextromilnacipran Levomilnacipran Serotonin Transporter , Norepinephrine
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.
T1189 Milnacipran hydrochloride Milnacipran HCl,Savella,Dalcipran Serotonin Transporter , Norepinephrine
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy...
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T0482 Sertraline hydrochloride Sertraline HCl,CP-51974-1 HCl 5-HT Receptor , Serotonin Transporter
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.
T10758L Centanafadine hydrochloride EB-1020 hydrochloride Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T2395 Vortioxetine Lu AA 21004 5-HT Receptor , Serotonin Transporter
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
T7940 Milnacipran ((1S-cis) hydrochloride) Levomilnacipran Hydrochloride Serotonin Transporter
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
T11087 DOV-216,303 Free Base DOV-216303 Dopamine Receptor , Serotonin Transporter , Norepinephrine
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
T1580 Desvenlafaxine WY 45233 Succinate,O-Desmethylvenlafaxine 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age...
T0450L Fluoxetine hydrochloride Fluoxetine HCl,LY-110140,Lilly110140 5-HT Receptor , Serotonin Transporter , Autophagy
Fluoxetine hydrochloride (Lilly110140) is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
T0472 Venlafaxine hydrochloride Venlafaxine HCl,Wy 45030 hydrochloride 5-HT Receptor , Serotonin Transporter
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is a cyclohexanol and phenylethylamine derivative that functions as a SEROTONIN AND NORADRENALINE REUPTAKE INHIBITOR (SNRI) and is used as an ANTIDEPRESSIVE AGENT.
T3526 Dasotraline hydrochloride SEP-225289 hydrochloride Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Dasotraline hydrochloride (SEP-225289 hydrochloride) (SEP-225289 hydrochloride) is a triple reuptake inhibitor that inhibits dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respe...
T1279 Vilazodone SB659746A,EMD 68843 5-HT Receptor , Serotonin Transporter
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from...
T6232 Vilazodone Hydrochloride SB659746A,EMD 68843,Vilazodone HCl Others , 5-HT Receptor , Serotonin Transporter
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
T7941 Imipramine hydrochloride Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine Serotonin Transporter
Imipramine hydrochloride (Imipramine HCl) is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).Imipramine hyd...
T6493 Escitalopram Oxalate Cipralex,(S)-(+)Citalopram oxalate Others , 5-HT Receptor , Serotonin Transporter
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
T0255 Clomipramine hydrochloride Clomipramine HCl,Anafranil Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine , GST
Clomipramine hydrochloride (Anafranil) is a tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demeth...
T1636 Paroxetine hydrochloride Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A 5-HT Receptor , Serotonin Transporter , GRK , AChR , Autophagy
Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.
T21013 Clomipramine Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina 5-HT Receptor
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of su...
T1077 Fluvoxamine maleate MK-264,DU-23000 (maleate) 5-HT Receptor , Serotonin Transporter
Fluvoxamine maleate (DU-23000 (maleate)) is a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.
T6188 Desvenlafaxine succinate hydrate O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine succinate hydrate (WY 45233 Succinate) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).
T2092 Amitifadine hydrochloride DOV-21947 hydrochloride,EB-1010 hydrochloride Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Amitifadine hydrochloride (EB-1010 hydrochloride) is a triple reuptake inhibitor (TRI) or serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
T6461 Dapoxetine hydrochloride LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy 5-HT Receptor , Serotonin Transporter
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
T0991 Desipramine hydrochloride NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020 Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor
Desipramine hydrochloride (Norimipramine) ,a secondary amine tricyclic antidepressant (TCA), is the hydrochloride salt form of desipramine. In the central nervous system (CNS), Desipramine hydrochloride blocks the re-upt...
T1471 Duloxetine hydrochloride Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Norepinephrine
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for SEROTONIN and NORADRENALINE (SNRI). It is an ANTIDEPRESSIVE AGENT and ANXIOLYTIC and i...
T1483 Citalopram hydrobromide Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr 5-HT Receptor , Serotonin Transporter , Autophagy
Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system...
T2395L Vortioxetine hydrobromide Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide 5-HT Receptor , Serotonin Transporter
Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33/3.7/19/1.6 nM).
T0678 Amitriptyline hydrochloride Amitriptyline HCl,Tryptizol,Domical,Annoyltin Trk receptor , Sigma receptor , 5-HT Receptor , Serotonin Transporter , Sodium Channel , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.
T0039 Dapoxetine Dapoxetina,Dapoxetinum Others , 5-HT Receptor
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
T12477 Uzansertib phosphate INCB053914 phosphate Pim
Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).
T6252 Ipatasertib GDC-0068,RG7440 Akt
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
T5818 Rigosertib sodium Rigosertib,Estybon,ON-01910 Apoptosis , PLK , PI3K
Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.
T15374 Ipatasertib dihydrochloride GDC-0068 dihydrochloride,RG-7440 dihydrochloride Akt , PKA
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively).
T5858 Sertindole Lu 23-174 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Autophagy
Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and the serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C (Kds = 2.7, 20, 0.14, and 6 nM, respectively)
T3351 Onatasertib CC223,CC 223,CC-223 Apoptosis , c-Fms , DNA-PK , FLT , PI3K , mTOR
Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity. Onatasertib inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor ce...
T6496 Vactosertib TEW-7197,EW-7197 ALK , TGF-beta/Smad
Vactosertib (EW-7197) is an orally bioavailable inhibitor of the serine/threonine kinase, transforming growth factor (TGF)-beta receptor type 1 (TGFBR1), also known as activin receptor-like kinase 5 (ALK5), with potentia...
T12642 (R)-Simurosertib (R)-TAK-931 CDK
(R)-Simurosertib ((R)-TAK-931) is an inhibitor of the ATP-competitive cell division cycle 7 (CDC7) kinase.
T10468 Elimusertib hydrochloride(1876467-74-1 free base) BAY-1895344 hydrochloride ATM/ATR
Elimusertib hydrochloride(1876467-74-1 free base) (BAY-1895344 hydrochloride) is a effective, orally available and selective ATR inhibitor with anti-tumor activity.
T3467 Miransertib ARQ-092,AKT inhibitor 2 Akt , Parasite
Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.
T2602 Barasertib-HQPA 1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811 Apoptosis , Aurora Kinase
Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
T6849 Uprosertib GSK2141795,GSK795 Akt
Uprosertib (GSK2141795) (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.

Compounds

SERT inhibitor 69419
T28758
Synonym:
Target:
SERT-IN-2
T73273
Synonym:
Target:
RAGE/SERT-IN-1
T72824
Synonym:
Target:
Paroxetine
T8708
Synonym:
Target: Serotonin Transporter
Nitroxazepine
T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
Duloxetine
T7061
Synonym:
Target: Serotonin Transporter
Fluoxetine
T0450
Synonym: LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Decynium 22
T22714
Synonym:
Target: Others
Venlafaxine
T22453
Synonym: Wy 45030
Target: Serotonin Transporter
Dextromilnacipran
T2594
Synonym: Levomilnacipran
Target: Serotonin Transporter, Norepinephrine
Milnacipran hydrochloride
T1189
Synonym: Milnacipran HCl,Savella,Dalcipran
Target: Serotonin Transporter, Norepinephrine
GSK163090
TQ0311
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Sertraline hydrochloride
T0482
Synonym: Sertraline HCl,CP-51974-1 HCl
Target: 5-HT Receptor, Serotonin Transporter
Centanafadine hydrochloride
T10758L
Synonym: EB-1020 hydrochloride
Target: Dopamine Receptor, Serotonin Transporter, Adrenergic Receptor, Norepinephrine
Vortioxetine
T2395
Synonym: Lu AA 21004
Target: 5-HT Receptor, Serotonin Transporter
Milnacipran ((1S-cis) hydrochloride)
T7940
Synonym: Levomilnacipran Hydrochloride
Target: Serotonin Transporter
DOV-216,303 Free Base
T11087
Synonym: DOV-216303
Target: Dopamine Receptor, Serotonin Transporter, Norepinephrine
Desvenlafaxine
T1580
Synonym: WY 45233 Succinate,O-Desmethylvenlafaxine
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Fluoxetine hydrochloride
T0450L
Synonym: Fluoxetine HCl,LY-110140,Lilly110140
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
Venlafaxine hydrochloride
T0472
Synonym: Venlafaxine HCl,Wy 45030 hydrochloride
Target: 5-HT Receptor, Serotonin Transporter
Dasotraline hydrochloride
T3526
Synonym: SEP-225289 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Vilazodone
T1279
Synonym: SB659746A,EMD 68843
Target: 5-HT Receptor, Serotonin Transporter
Vilazodone Hydrochloride
T6232
Synonym: SB659746A,EMD 68843,Vilazodone HCl
Target: Others, 5-HT Receptor, Serotonin Transporter
Imipramine hydrochloride
T7941
Synonym: Imipramine (hydrochloride),Tofranil,G 22355,Imipramine HCl,Melipramine
Target: Serotonin Transporter
Escitalopram Oxalate
T6493
Synonym: Cipralex,(S)-(+)Citalopram oxalate
Target: Others, 5-HT Receptor, Serotonin Transporter
Clomipramine hydrochloride
T0255
Synonym: Clomipramine HCl,Anafranil
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine, GST
Paroxetine hydrochloride
T1636
Synonym: Paroxetine HCl,BRL29060 hydrochloride,FG-7051,BRL29060A
Target: 5-HT Receptor, Serotonin Transporter, GRK, AChR, Autophagy
Clomipramine
T21013
Synonym: Chlorimipramine,Anafranil,Clomicalm,Anafranil (free base),Clomipramina
Target: 5-HT Receptor
Fluvoxamine maleate
T1077
Synonym: MK-264,DU-23000 (maleate)
Target: 5-HT Receptor, Serotonin Transporter
Desvenlafaxine succinate hydrate
T6188
Synonym: O-Desmethylvenlafaxine succinate hydrate,WY 45233 Succinate,Desvenlafaxine Succinate
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
Amitifadine hydrochloride
T2092
Synonym: DOV-21947 hydrochloride,EB-1010 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Dapoxetine hydrochloride
T6461
Synonym: LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy
Target: 5-HT Receptor, Serotonin Transporter
Desipramine hydrochloride
T0991
Synonym: NSC-114901,Desmethylimipramine,JB-8181,EX-4355,Norimipramine,G-35020
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor
Duloxetine hydrochloride
T1471
Synonym: Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Citalopram hydrobromide
T1483
Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,Citalopram HBr
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
Vortioxetine hydrobromide
T2395L
Synonym: Vortioxetine (Lu AA21004) HBr,Vortioxetine HBr,Lu AA21004 hydrobromide
Target: 5-HT Receptor, Serotonin Transporter
Amitriptyline hydrochloride
T0678
Synonym: Amitriptyline HCl,Tryptizol,Domical,Annoyltin
Target: Trk receptor, Sigma receptor, 5-HT Receptor, Serotonin Transporter, Sodium Channel, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Dapoxetine
T0039
Synonym: Dapoxetina,Dapoxetinum
Target: Others, 5-HT Receptor
Uzansertib phosphate
T12477
Synonym: INCB053914 phosphate
Target: Pim
Ipatasertib
T6252
Synonym: GDC-0068,RG7440
Target: Akt
Rigosertib sodium
T5818
Synonym: Rigosertib,Estybon,ON-01910
Target: Apoptosis, PLK, PI3K
Ipatasertib dihydrochloride
T15374
Synonym: GDC-0068 dihydrochloride,RG-7440 dihydrochloride
Target: Akt, PKA
Sertindole
T5858
Synonym: Lu 23-174
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Autophagy
Onatasertib
T3351
Synonym: CC223,CC 223,CC-223
Target: Apoptosis, c-Fms, DNA-PK, FLT, PI3K, mTOR
Vactosertib
T6496
Synonym: TEW-7197,EW-7197
Target: ALK, TGF-beta/Smad
(R)-Simurosertib
T12642
Synonym: (R)-TAK-931
Target: CDK
Elimusertib hydrochloride(1876467-74-1 free base)
T10468
Synonym: BAY-1895344 hydrochloride
Target: ATM/ATR
Miransertib
T3467
Synonym: ARQ-092,AKT inhibitor 2
Target: Akt, Parasite
Barasertib-HQPA
T2602
Synonym: 1H-Pyrazole-3-acetamide,Barasertib,AZD1152-HQPA,AZD2811,AZD1152-HQPA|AZD2811
Target: Apoptosis, Aurora Kinase
Uprosertib
T6849
Synonym: GSK2141795,GSK795
Target: Akt
1 2 3 4
Cat No. Product Name Synonyms Targets
T7521 Azaphen Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen 5-HT Receptor , Serotonin Transporter
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T1317 Cinchonidine α-Quinidine,L-Cinchonidine 5-HT Receptor , Serotonin Transporter , Parasite
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram Dopamine Receptor , 5-HT Receptor , Serotonin Transporter , Adrenergic Receptor , AChR , Norepinephrine , Histamine Receptor
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patien...
T36029 Desertomycin A
Desertomycin A is fungal metabolite and the major component of the desertomycin antibiotic complex that has been found in S. flavofungini.
T19772 Mesembrenone (+)-Mesembrenone
Mesembrenone is a selective the serotonin transporter (SERT) inhibitor. Mesembrenone is the main alkaloid of Sceletium tortuosum.
T75530 Nardoguaianone J
Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].

Natural Products

Azaphen
T7521
Synonym: Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen
Target: 5-HT Receptor, Serotonin Transporter
Cinchonidine
T1317
Synonym: α-Quinidine,L-Cinchonidine
Target: 5-HT Receptor, Serotonin Transporter, Parasite
Escitalopram
T0185
Synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
Desertomycin A
T36029
Synonym:
Target:
Mesembrenone
T19772
Synonym: (+)-Mesembrenone
Target:
Nardoguaianone J
T75530
Synonym:
Target:
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