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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T82372 | Free radical scavenger 1 | ||
Compound 8, a free radical scavenger, exhibits an IC50 value of 43.39 μg/ml in neutralizing the DPPH radical [1]. | |||
T8794 | 4-MMPB | 15-Lipoxygenase Inhibitor 1 | Apoptosis , Others , Lipoxygenase |
15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM. 4-MMPB (15-Lipoxygenase Inhibitor 1) has IC50s of 19.5 μM and 19.1 μM for soybean 15-lipoxygenase (SLO) and human 15-lipoxyg... | |||
T7717 | Sodium 2-oxopropanoate | Sodium pyruvate | Reactive Oxygen Species , Endogenous Metabolite |
Sodium 2-oxopropanoate (Sodium pyruvate) is a antioxidant potentially used to treatment of chronic obstructive pulmonary disease. | |||
T5363 | Tempo | 2,2,6,6-Tetramethylpiperidinooxy | Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism |
Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. | |||
T5678 | Lazabemide hydrochloride | N-(2-Aminoethyl)-5-chlor-2-pyridincarbox | MAO , Monoamine Oxidase |
Lazabemide hydrochloride (N-(2-Aminoethyl)-5-chlor-2-pyridincarbox) is a reversible and selective mao-b inhibitor(Ki:7.9nM). | |||
T21233 | Dihydrolipoic acid | Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid | Antioxidant |
Dihydrolipoic acid (USAF XR-12), a dithiol-containing carboxylic acid, acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including peroxynitirite, hydroxyl radicals, hydr... | |||
T5470 | LAZABEMIDE | Ro 19-6327 | MAO , Monoamine Oxidase |
Lazabemide (Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). | |||
T9324 | 1,5-diphenylpyrazole-3-carboxylic acid | 1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL- | Others |
1,5-diphenylpyrazole-3-carboxylic acid (1H-PYRAZOLE-3-CARBOXYLIC ACID, 1,5-DIPHENYL-) is a plant-physiologically tolerable salt radical or any desired ester radical. | |||
T6606 | Nicaraven | Others | |
Nicaraven, a hydroxyl radical scavenger, has neuroprotective and antivasospastic effects. | |||
T9511 | Monoethyl itaconate | Others | |
Monoethyl itaconate is a free radical that can be used for polymerization | |||
T17111 | Todralazine hydrochloride | Ecarazine hydrochloride | Adrenergic Receptor |
Todralazine hydrochloride (Ecarazine hydrochloride) is a β2AR blocker and has antioxidant and free radical scavenging activities. Todralazine hydrochloride can be used in anti-hypertensive research. | |||
T3289 | Amifostine | Ethyol,WR2721,Gammaphos | Others , HIF/HIF Prolyl-Hydroxylase |
Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity. | |||
T20736 | Cryptating agent 222 | Cryptate 222,NSC 264495,NSC-264495,NSC264495 | Others |
Cryptating agent 222 (NSC-264495) is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion and forms ligands with metal cations. | |||
T11093 | DPPH | 2,2-Diphenyl-1-picrylhydrazyl | Others |
DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a cell-permeable, stable free radical that is commonly used to evaluate the ability of compounds to act as free radical scavengers or hydrogen donors and to measure the antioxidant... | |||
T0407 | Edaravone | MCI-186 | Apoptosis , MMP , Free radical scavengers |
Edaravone (MCI-186)(MCI-186) is a potent new free radical scavenger used for the therapy of patients with acute brain infarction. | |||
T30908 | Chromotrope 2B | C.I. Acid Red 176,Chromotrope2B,Chromotrope-2B,Chromotrope Red 4B | Others |
Chromotrope 2B (C.I. Acid Red 176) is a reagent for analytical determination of boric acid and borates, and is also used to produce a highly colored radical anion in conjuction with Chromotrope 2R. | |||
T1344 | 4-Chloro-4'-hydroxybenzophenone | Others | |
4-Chloro-4'-hydroxybenzophenone inhibits tyrosinase and also acts as a free radical scavenger or antioxidant, reducing lipid and protein oxidation. | |||
T41345 | AFMK | Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine | Apoptosis , Free radical scavengers , Antioxidant , Endogenous Metabolite |
AFMK (Formyl-N-acetyl-5-methoxykynurenamine) is an active metabolite of Melatonin with antioxidant and free radical scavenging activity. AFMK is a modulator of apoptosis and improves the anti-tumor effect of Gemcitabine ... | |||
T36506 | Tempone | 4-Oxo-tempo | |
Tempone is an aminooxyalkane that acts as a free radical scavenger and reacts with reactive oxygen species (ROS). Intravenous Tempone reduces mean arterial pressure in spontaneously hypertensive rats. | |||
T21343 | PTZ-343 | PTZ-343 sodium,PTZ 343 | Others |
PTZ-343 is a potent enhancer of Luminol, acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission. | |||
T78554 | Tyrosinase-IN-12 | Tyrosinase | |
Tyrosinase-IN-12(Non-competitive tyrosinase inhibitor) is a potent non-competitive tyrosinase inhibitor with an IC50 of 49.33 ± 2.64 µM and a Ki of 31.25 ± 0.25 µM. Tyrosinase-IN-12 has significant antioxidant and free r... | |||
T77478 | Milatuzumab | hLL1,MEDI-115 | Others |
Milatuzumab (MEDI-115) is a humanized monoclonal antibody against CD74. Milatuzumab promotes the production of free radical oxygen and the loss of mitochondrial membrane potential, reduces CD20/CD74 aggregates and cell a... | |||
T1229 | Erdosteine | RV 144,KW-9144 | NF-κB , Antibacterial , Adenosine deaminase |
Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucocili... | |||
T65288 | Methacrylic anhydride | Others | |
Methacrylic anhydride is a polymerizable 1,6-diolefin compound that can be radical-initiated to form soluble cyclohexane polymers.Methacrylic anhydride can spontaneously polymerize via vinyl groups, which is inhibited by... | |||
T7037 | 7-Acetoxy-4-methylcoumarin | MU-Ac | Others |
7-Acetoxy-4-methylcoumarin is a fluorogenic substrate for carboxylesterase yielding a blue fluorescent solution upon cleavage. The compound has been used in aprotic media, a cell membrane environmental mimic, to study su... | |||
T9948 | NecroX-7 | LC-280126,LC28-0126,LC28 0126 | NADPH-oxidase |
NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing ... | |||
T12781 | RV01 | Others | |
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc... | |||
T28222 | 5-Hydroxy-1-methylhydantoin | HD-003,HD003,NZ419,NZ-419,HD 003,NZ 419 | Bradykinin Receptor |
5-Hydroxy-1-methylhydantoin (HD-003) is an antioxidant potentially for the treatment of renal failure. A creatinine metabolite, 5-Hydroxy-1-methylhydantoin , a hydroxyl radical scavenger, has previously been shown to con... | |||
T28673 | SB 209995 | SB-209995,SB209995 | |
SB 209995, a potent antioxidant, inhibits oxygen-radical-mediated lipid peroxidation and cytotoxicity. | |||
T23853 | Carazostatin | ||
Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor. | |||
T35766 | SAHO | ||
SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine s... | |||
T35767 | SAHO2 | ||
SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radica... | |||
T17112 | Todralazine | Ecarazine | Others |
Todralazine is an anti-hypertensive agent and acts as a β2AR blocker. It also has an antioxidant and free radical scavenging activity. | |||
T10253 | AD 0261 | Others | |
AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions. | |||
T0260L | Meclofenamate sodium hydrate | INF 4668,CI583,CI-583,INF-4668,CI 583,INF4668 | |
Meclofenamate sodium is a potent non-steroidal anti-inflammatory agent, which can specifically inhibit chemokine-induced human polymorphonuclear leukocyte function: chemotaxis, degranulation, and superoxide anion free ra... | |||
T21079 | Decafluorobenzophenone | Perfluorobenzophenone | |
Decafluorobenzophenone is used in the synthesis of fluorinated acridones and acridines. Decafluorobenzophenone alcoholic solution generates radical anion and ketyl which can be studied by electron spin resonance spectra.... | |||
T39205 | HKSOX-1 | ||
HKSOX-1 is a fluorescent probe which is used for imaging and detection of endogenous superoxide in live cells and in vivo. HKSOX-1 exhibits excellent selectivity and sensitivity towards superoxide anion radical. | |||
T78067 | Stobadine | (-)-Stobadine | Reactive Oxygen Species |
Stobadine, a potent antioxidant, safeguards endoplasmic reticulum (ER) membrane fluidity against free radical-induced changes. It shows promise in the development of cardio- and neuroprotective agents owing to its mechan... | |||
T11152 | Edaravone-d5 | MCI-186 D5 | Others |
Edaravone, a novel and potent free radical scavenger, effectively prevents MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator. Its deuterium-labeled variant, Edaravone D5, retains the origin... | |||
T36175 | AAPH | ||
AAPH is a water-soluble azo compound which is used extensively as a free radical generator, often in the study of lipid peroxidation and the characterization of antioxidants.[1],[2],[3],[4] Decomposition of AAPH produces... | |||
T38935 | Cu(II) protoporphyrin IX | ||
Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical for... | |||
T38071 | HPF | ||
The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescen... | |||
T41058 | Nelonemdaz potassium | Neu2000potassium,Salfaprodil | |
Nelonemdaz potassium (also known as Salfaprodil) is a potent NR2B-selective and uncompetitive antagonist of N-methyl-D-aspartate (NMDA). This compound exhibits remarkable neuroprotection against cell death induced by bot... | |||
T40979 | XJB-5-131 | ||
XJB-5-131 is a synthetic, bi-functional antioxidant specifically designed to target mitochondria for the scavenging of reactive oxygen species (ROS) and electrons, thereby acting as a radical scavenger. Additionally, it ... | |||
T68948 | Detorubicin HCl | ||
Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair... | |||
T68909 | Detorubicin Free Base | ||
Detorubicin Free Base is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication ... | |||
T81279 | RhB-PBP10 TFA | ||
RhB-PBP10 TFA, a Rhodamine B-labeled PBP10 TFA (FPR2 antagonist), selectively inhibits granule mobilization and oxygen radical secretion in FPRL1-induced neutrophils [1]. | |||
T36164 | 8-iso Prostaglandin F3α | 8-iso Prostaglandin F3α,8-epi PGF3α | |
8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of h... | |||
T61579 | BuChE-IN-5 | ||
BuChE-IN-5 (compound 25b) is a highly potent BuChE inhibitor, displaying an IC50 value of 1.94 μM. It effectively inhibits aggregation of Aβ and tau protein in Escherichia coli. Furthermore, BuChE-IN-5 exhibits considera... | |||
T25943 | Phenazoviridin | ||
Phenazoviridin is a newly discovered microbial free radical scavenger isolated from the culture medium of Streptomyces HR04. It is an anti-hypoxic compound with strong inhibitory activity against lipid peroxidation in ra... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1873 | Lirinidine | Others | |
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a... | |||
T9057 | Norbergenin | IL Receptor , TNF , Reactive Oxygen Species | |
Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi. | |||
TN1058 | Pelargonidin chloride | NOS , Reactive Oxygen Species , Nrf2 , NO Synthase | |
Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. | |||
TN1621 | Eriodictyol-7-O-glucoside | Nrf2 | |
Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radical scavenger with antioxidant activity in pistachio skin. | |||
T6S1440 | Loganic acid | Loganate | Others |
1. Loganic acid (Loganate) and geniposide exhibit both sides effect on superoxide generation. | |||
T9135 | Epirosmanol | Others | |
Epirosmanol is a diterpenoid containing a lactone moiety. Epirosmanol is a very weakly basic (essentially neutral) compound (based on its pKa). | |||
T2S1181 | Aloenin | Aloenin A,Aloearbonaside | Beta-Secretase , AChR |
1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro. | |||
T41358 | 2-Hydroxybenzylamine | Others | |
2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a... | |||
T22308 | Dimboa | 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one | Others , Antibacterial , Antibiotic , Antifungal |
Dimboa (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) is an antifungal compound used in crops. | |||
TN6706 | 3-demethylcolchicine | Reactive Oxygen Species | |
3-demethylcolchicine is a natural product isolated from Gloriosa superba.Inhibitory effect on the polymerization of purified bovine brain tubulin. | |||
TN2011 | Ombuoside | Ombuin-3beta-rutinoside | Antibacterial |
Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma penta... | |||
TN2165 | Rubrofusarin gentiobioside | Rubrofusarin-6-O-beta-D-gentiobioside | ERK , NF-κB , TGF-beta/Smad |
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive... | |||
T37710 | 5-Hydroxyoxindole | Reactive Oxygen Species | |
5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit... | |||
TN6909 | Polyporusterone B | (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one | Others |
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci... | |||
T1648 | α-Vitamin E | Dexrabeprazole Sodium,Vitamin E,Alpha-Tocopherol,D-α-Tocopherol,5,7,8-Trimethyltocol,(+)-alpha-Tocopherol | Others , Ferroptosis , Influenza Virus , Reactive Oxygen Species , Endogenous Metabolite , Antibacterial , PKC , GST |
α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. | |||
T5S0281 | Tubuloside A | NOS | |
Tubuloside A ( 8.6 microM) can inhibit D-galactosamine-induced death of hepatocytes. Tubuloside A has NO radical-scavenging activity, which possibly contributes to its anti-inflammatory effects.Tubuloside A shows stronge... | |||
T2S1086 | Nepitrin | Nepetin-7-glucoside | Antioxidant |
1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation. | |||
T2778 | (+)-Catechin Hydrate | Antioxidant , COX | |
(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. | |||
T2936 | Antiarol | 3,4,5-trimethoxyphenol | Others |
Antiarol (3,4,5-trimethoxyphenol) is a member of aromatic phenols and exhibits moderate DPPH free radical scavenging activity. | |||
T7034 | 1-IODOADAMANTANE | 1-Adamantyl Iodide,Adamantyl iodide | Others |
1-IODOADAMANTANE (1-Adamantyl Iodide) is employed in the free-radical carbonylation reactions with alkenes. | |||
T7781 | Reynoutrin | Reinutrin,Quercetin-3-D-xyloside | Reactive Oxygen Species |
Reynoutrin (Reinutrin) with antioxidant and radical-scavenging activity. | |||
T3845 | (+)-Gallocatechin | Gallocatechol,D-Gallocatechin | Others |
(+)-Gallocatechin (Gallocatechol) possesses free radical scavenging ability. (+)-Gallocatechin has moderate affinity to the human cannabinoid receptor. | |||
TN1002 | Blumeatin | ROS | |
Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity. | |||
TN1513 | Clitorin | PKC , Antifection | |
Clitorin has free radical scavenging property. It shows significant interactions with CD38, it may have anti-hyperglycemic potential. | |||
TN1137 | Isobutylshikonin | Others | |
Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·. | |||
T3828 | (-)-Gallocatechin | (2S,3R)-gallocatechin,(−)-GC | Others |
(-)-Gallocatechin ((−)-GC) has free radical scavenging ability and moderate affinity to the human cannabinoid receptor. | |||
TN7126 | N-Vanillyloctanamide | Others | |
N-Vanillyloctanamide is a capsaicinoid from the fruits of Capsicum annuum L. var. annuum. N-Vanillyloctanamide reduces the radical length of Lactuca sativa seedling, this inhibition being dose-dependent. | |||
TN2008 | Okanin | NF-κB , TLR | |
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect. | |||
TN1916 | Matairesinol | ATPase , p38 MAPK , ROS | |
Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS signaling , can decrease hypoxia-inducible factor-1α± in hypoxic HeLa cells. | |||
T2S1434 | Bergaptol | 5-Hydroxyfuranocoumarin,4-Hydroxybergapten,5-Hydroxypsoralen | P450 |
1. Bergaptol (4-Hydroxybergapten) shows very good radical scavenging activity. 2. Bergaptol is a potent inhibitor of debenzylation activity of CYP3A4 enzyme. | |||
T3905 | Isomangiferin | Free radical scavengers , Antiviral , Influenza Virus | |
Isomangiferin has an antiviral effect, may due to their capability of inhibiting virus replication within cells. It also has antioxidant and radical-scavenging activities. | |||
TN1490 | Chrysoeriol | ERK , p38 MAPK , Akt | |
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect. | |||
T3093 | Spermine tetrahydrochloride | Spermine Tetrahydrochloride,Neuridine tetrahydrochloride,Musculamine tetrahydrochloride,Gerontine tetrahydrochloride | Others , Endogenous Metabolite |
Spermine tetrahydrochloride (Musculamine tetrahydrochloride) is a polyamine involved in cellular metabolism found in all eukaryotic cells. It is a major natural intracellular compound capable of protecting DNA from free ... | |||
T4937 | DL-5-Hydroxylysine hydrochloride | 5-hydroxylysine hydrochloride | Others , Endogenous Metabolite |
DL-5-Hydroxylysine hydrochloride (5-hydroxylysine hydrochloride) is a racemic mixture of D- and L- enantiomers of 5-hydroxylysine which may be used as potential target markers for radical-induced protein oxidation. | |||
TN1274 | 4-Allylcatechol | 4-Allylpyrocatechol,Hydroxychavicol | Others |
4-Allylcatechol (Hydroxychavicol) has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical ... | |||
T3406 | Kuromanin chloride | Glucocyanidin chloride,Chrysontemin,Chrysontemin chloride,Cyanidin 3-O-glucoside chloride | NF-κB |
Kuromanin chloride (Chrysontemin chloride) is potent antioxidants and free radical scavengers, may act as modulators of gene regulation and signal transduction pathways. | |||
TN1125 | Neonuezhenide | Antioxidant | |
Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells. | |||
TN1558 | N-Vanillyldecanamide | Decylic acid vanillylamide | Others |
N-Vanillyldecanamide (Decylic acid vanillylamide), isolated from fruits of Capsicum annuum, significantly reduced free radical length in alfalfa seedlings in a dose-dependent manner. | |||
T8087 | Tropolone | Tyrosinase | |
Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion | |||
TN3601 | Carminic acid | ROS | |
Carminic acid, the well-known red dyestuff from cochineal insects (Dactylopius spp.), is a potent feeding deterrent to ants. Carminic acid is an antioxidant to protect erythrocytes and DNA against radical-induced oxidati... | |||
TN1816 | Kadsurin | Antioxidant | |
Kadsurin has anti-oxidant activity, it induces enzymes capable of scavenging oxygen radical species in the liver. Kadsurin may be valuable antitumor promoters or chemopreventors. | |||
T2759 | Loganin | Loganoside | Apoptosis , NF-κB , BACE , AChR , AChE |
Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent free-radical-scavenging activity and inhibitor... | |||
TN6489 | Regaloside A | Others | |
Regaloside A is a phenylpropane derived from lily of the valley that shows DPPH free radical scavenging activity at 160 ppm.Regaloside A has anti-inflammatory activity and antidepressant activity. | |||
T3383 | Cimifugin | Cimitin | Others |
Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system. | |||
TN6908 | Polyporusterone A | (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R,5S)-2,3-dihydroxy-5,6-dimethylheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one | |
Polyporusterone A is a triterpene carboxylic acid derived from the substrates of P. umbellatus.Polyporusterone A inhibits free radical-induced erythrocyte cleavage (hemolysis), and can be used in studies of hair regenera... | |||
TN1644 | Flavanomarein | Others | |
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea... | |||
T5731 | 1-Kestose | Others , Endogenous Metabolite , Antibacterial | |
1-Kestose shows significant anti-hydroxyl radical potential. 1-Kestose can promote intestinal Lactobacillus number, and influence the microorganisms as well as the intestinal and systemic immune responses. | |||
TN2031 | γ-Terpinene | Moslene,p-Mentha-1,4-diene,Crithmene | Antioxidant |
γ-Terpinene (p-Mentha-1,4-diene) is a monoterpene compound with high antioxidant properties suitable for oral consumption. It displays direct radical scavenging abilities and is known to be a potent antinociceptive agent... | |||
TN1788 | Isookanin | Amylase | |
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml). | |||
T1716 | Echinacoside | Reactive Oxygen Species , Wnt/beta-catenin | |
Echinacoside is a natural polyphenolic compound with various kinds of pharmacological activities, such as anti-inflammatory, antioxidative, hepatoprotective, neuroprotective, nitric oxide radical-scavenging and vasodilat... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03407 | NQO1 Protein, Human, Recombinant (His) | Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-... | |||
TMPH-02997 | Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO) | Mycobacterium smegmatis | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ... | |||
TMPH-00567 | MTA/SAH nucleosidase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy... | |||
TMPH-00692 | MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy... | |||
TMPJ-00934 | PRDX3 Protein, Human, Recombinant | Human | E. coli |
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and hu... | |||
TMPH-03702 | MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) | Vibrio cholerae | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy... | |||
TMPY-02044 | SOD2 Protein, Human, Recombinant | Human | E. coli |
Superoxide dismutases (SOD) are important anti-oxidant enzymes that guard against superoxide toxicity. In humans, as in all mammals and most chordates, three forms of superoxide dismutase (SOD) are present: SOD1 is locat... | |||
TMPH-01080 | Ceruloplasmin Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the ... | |||
TMPH-00794 | Dps Protein, Helicobacter pylori, Recombinant (His & SUMO) | Helicobacter pylori | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ... | |||
TMPH-00646 | LexA repressor Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA int... | |||
TMPY-02401 | Tyrosine Hydroxylase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw... | |||
TMPY-02587 | Tyrosine Hydroxylase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw... | |||
TMPH-00617 | MazF Protein, E. coli, Recombinant (His) | E. coli | Yeast |
Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific endoribonuclease it inhibits protein synthesis by cleaving mRNA and inducing bacterial stasis. It is stable, single-strand specific with mRNA ... |
Cat No. | Product Name | ||
---|---|---|---|
L2900 | Oxidation-Reduction Compound Library | 1279 compounds | |
1279 small molecule compounds with pro-oxidant or anti-oxidant activity for high-throughput and high-content screening. |