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Cat No. | Product Name | Synonyms | Targets |
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T79923 | T7 RNA polymerase | DNA/RNA Synthesis | |
T7 RNA polymerase, expressed by Escherichia coli from the T7 bacteriophage RNA polymerase gene, is a highly specific enzyme utilized for in vitro transcription (IVT) of mRNA. This polymerase requires Mg 2+ and selects on... | |||
T79924 | T4 RNA ligase | DNA/RNA Synthesis | |
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA. It is utilized for the synthesis of enzymatic oligoribonucleotides and the 3′-terminal labeling of RNA [1] [2]. | |||
T74886 | RNA splicing modulator 3 | ||
RNA splicing modulator 3 (compound 236) is a RNA splicing modulator, with an AC 50 value of <100 nM [1] . | |||
T74884 | RNA splicing modulator 1 | ||
RNA splicing modulator 1 (compound 233) is a RNA splicing modulator, with an AC 50 value of <100 nM [1] . | |||
T74885 | RNA splicing modulator 2 | ||
RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] . | |||
T74630 | RNA polymerase II-IN-1 | DNA/RNA Synthesis | |
RNA polymerase II-IN-1 (compound 19iv), an amatoxin, selectively inhibits RNA polymerase II (Pol II) with an IC50 of 36.66 nM. It exhibits heightened cytotoxicity towards cancer cells and reduced toxicity in normal cells... | |||
T74631 | RNA polymerase II-IN-2 | ||
RNA polymerase II-IN-2 (compound 20iii) is a potent RNA polymerase II (Pol II) inhibitor with K i value of 9.5 nM. RNA polymerase II-IN-2 has cytotoxicity against cancer cells, and exhibits 2 and 5 fold toxicity than α-a... | |||
T81356 | PTBP1-RNA-binding inhibitor P6 TFA | PTBP1 α3-helix derived peptide P6 TFA | |
PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide that acts as an inhibitor for the splicing factor PTBP1, targeting the alternative splicing events this protein regulates. It op... | |||
T83729 | Tat-CIRP TFA | Tat-Cold-inducible RNA Binding Protein | |
Tat-CIRP, a peptide inhibitor, impedes the protein-protein interaction between myeloid differentiation 2 (MD-2), also known as lymphocyte antigen 96 (LY96), and cold-inducible RNA binding protein (CIRP) by binding to MD-... | |||
TD0005 | SYBR GREEN II | SUPER Green II RNA gel stain *10,000× concentrate in DMSO* (Electrophoresis Grade) | |
1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-... | |||
T36971 | 5-Ethynyluridine | Nucleoside Antimetabolite/Analog | |
5-Ethynyluridine is a clickable form of uridine.1It is incorporated into cellular RNA, but not DNA, and has been used to detect transcriptionin vitroandin vivo. 1.Jao, C.Y., and Salic, A.Exploring RNA transcription and t... | |||
T1349 | 5-Fluorouridine | Others , DNA/RNA Synthesis | |
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compound... | |||
T8354 | Triazavirin | Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis | |
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent. | |||
T1767 | BMH-21 | BMH21 | DNA/RNA Synthesis |
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX. | |||
T6801 | CeMMEC13 | Carboxypeptidase , DNA/RNA Synthesis | |
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM). | |||
T26674 | AT-130 | AT 130 | HBV , DNA/RNA Synthesis |
AT-130 is a HBV virus inhibitor with improved potency (IC50 = 0.13 μM) and reduced toxicity in the HepAD38 cell line. AT-130 blocks HBV replication at the level of viral RNA packaging. | |||
T13166 | TK216 | Others , DNA/RNA Synthesis | |
TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity. | |||
T12019 | Methylproamine | Others | |
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA. | |||
T15611 | JH-RE-06 | DNA/RNA Synthesis | |
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact... | |||
T1154 | Rifaximin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting... | |||
TP1115 | L-Asparaginase | L-ASNase | Others |
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a... | |||
T3489 | Dasabuvir | ABT-333 | HCV Protease |
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra... | |||
T4686 | Simeprevir | TMC435,TMC-435350,Olysio | HCV Protease , SARS-CoV |
Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM. | |||
T2100 | CX-5461 | DNA/RNA Synthesis | |
CX-5461, a selective inhibitor of rRNA synthesis, suppresses Pol I-driven transcription of rRNA. | |||
T8886 | NITD-2 | DNA/RNA Synthesis | |
NITD-2 is a dengue virus (DENV) polymerase inhibitor, inhibits the DENV RdRp-mediated RNA elongation. NITD-2 penetrates cell membrane poorly. Dengue virus (DENV) is the most prevalent mosquito- borne viral pathogen in hu... | |||
T8955 | PCNA-I1 | Others | |
PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer. | |||
T2037 | TH588 | DNA/RNA Synthesis , MTH1 | |
TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells. | |||
T16961 | Supinoxin | RX-5902 | Apoptosis , DNA/RNA Synthesis |
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50... | |||
T40168 | DHODH-IN-16 | Dehydrogenase | |
DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human). | |||
T2410 | Nedaplatin | NSC 375101D | DNA/RNA Synthesis |
Nedaplatin (NSC-375101D) is a derivative of cisplatin and DNA damage agent for tumor colony forming units (IC50: 94 μM). Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand... | |||
T36687 | Ac-rC Phosphoramidite | Nucleoside Antimetabolite/Analog | |
Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides. | |||
T15235 | Enocitabine | Nucleoside Antimetabolite/Analog , HCV Protease , DNA/RNA Synthesis | |
Enocitabine is a nucleoside analog. Enocitabine inhibits the replication of human cytomegalovirus(HCMV) and it also has antileukemic and antiviral activities. Enocitabine is also a potent DNA replication inhibitor and a ... | |||
T8873 | Bractoppin | Others , DNA/RNA Synthesis | |
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi... | |||
T35648 | 4-Thiouridine | Others | |
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl... | |||
T38889 | Thailanstatin A | ||
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 =650 nM). Thailanstatin A inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the s... | |||
T36757 | DMT-dU-CE Phosphoramidite | DNA/RNA Synthesis | |
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA. | |||
T7747 | Datelliptium chloride hydrochloride | DNA/RNA Synthesis | |
Datelliptium chloride hydrochloride is a DNA-intercalating agent derived from ellipticine. with anti-tumor activities. | |||
T14501 | BAY-2402234 | Dehydrogenase , DNA/RNA Synthesis | |
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity. | |||
T38237 | 2′-O-Methylcytidine | Nucleoside Antimetabolite/Analog , HCV Protease | |
2'-O-Methylcytidine is a nucleoside derivative and an inhibitor of hepatitis C virus (HCV) non-structural protein 5B (NS5B; IC50= 3.8 μM).1It inhibits HCV replication in a replicon assay (IC50= 21.2 μM). 1.Migliaccio, G.... | |||
T16703 | Quarfloxin | CX-3543 | DNA/RNA Synthesis |
Quarfloxin (CX-3543) is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-... | |||
T1233 | Oxolinic acid | Emyrenil,Nidantin,NSC 110364,Dioxacin,Urinox | Dopamine Receptor , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS. | |||
T9111 | 8-Azaadenosine | Adenosine deaminase | |
8-Azaadenosine is a potent ADAR1 inhibitor and an A-to-I editing inhibitor. It blocks RNA editing and inhibits proliferation, 3D growth, invasion, and migration in thyroid cancer cells. | |||
T40661 | ML-60218 | DNA/RNA Synthesis | |
ML-60218 is an inhibitor of broad-spectrum RNA pol III with IC50s of 32 and 27 μM for Saccharomyces cerevisiae and human. ML-60218 disrupts already assembled viroplasms and hampers the formation of new viroplasms. | |||
T9103 | BVDV-IN-1 | DNA/RNA Synthesis | |
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. It directly binds to a hydrophobic pocket of the BVDV RdRp. It has antiviral activity against BVDV resistant to... | |||
T11020 | DHODH-IN-11 | Dehydrogenase , DNA/RNA Synthesis | |
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | |||
T4345 | CeMMEC1 | CeMMEC1 HCl | Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis |
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM). | |||
T12438 | PfDHODH-IN-1 | Dehydrogenase , Parasite | |
PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity. | |||
T8747 | Levofloxacin hydrochloride | DNA gyrase , Topoisomerase | |
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inh... | |||
T9121 | AG-636 | Dehydrogenase , DNA/RNA Synthesis | |
AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects. | |||
T14495 | Baloxavir | Baloxavir acid,S-033447 | Influenza Virus |
Baloxavir (S-033447) is a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13969 | Xanthopterin (hydrate) | Others , DNA/RNA Synthesis | |
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species. | |||
T13499 | 3-Methyluridine | Endogenous Metabolite | |
3-Methyluridine is a modified nucleoside of cellular RNA. | |||
T40179 | Sodium Camptothecin | DNA/RNA Synthesis | |
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i... | |||
T2S1635 | 3-Isomangostin | MTH1 | |
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac... | |||
T24729 | Roseoflavin | Antibacterial | |
Roseoflavin, a chemical analog of FMN and riboflavin that has antimicrobial activity, can directly bind to FMN riboswitch aptamers and downregulate the expression of an FMN riboswitch-lacZ reporter gene in B. subtilis. | |||
T5901 | 3-Hydroxy-2-methylpyridine | Others | |
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors. | |||
T5270 | 5-Methylcytosine | Others , DNA/RNA Synthesis , Endogenous Metabolite | |
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated... | |||
TN1134 | Euscaphic acid | Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor | |
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of... | |||
T21498 | Phleomycin | DNA/RNA Synthesis , Antibacterial , Antibiotic | |
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix. | |||
T1465 | Mupirocin | Pseudomonic acid,BRL-4910A | DNA/RNA Synthesis , Antibacterial , Antibiotic |
Mupirocin (BRL-4910A) is a RNA synthetase inhibitor antibacterial. It has shown excellent activity against gram-positive staphylococci and streptococci. | |||
T37101 | 1-Hydroxyanthraquinone | DNA/RNA Synthesis | |
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response. | |||
T8148 | Mupirocin calcium hydrate | Mupirocin calcium | Others , Antibacterial , Antibiotic |
Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria | |||
T35455 | N-Nitrosodiethylamine | Diethylnitrosamine,NDEA | DNA/RNA Synthesis |
N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso... | |||
TQ0184 | Chebulinic acid | ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad | |
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. | |||
T6S0232 | Eriodictyol | Huazhongilexone | Influenza Virus , DNA/RNA Synthesis , Nrf2 , Endogenous Metabolite |
1. Eriodictyol (Huazhongilexone) is a flavonoid with anti-inflammatory and antioxidant activities. 2. Eriodictyol may possess antidiabetic properties through increasing glucose uptake and improving insulin resistance. 3.... | |||
T1068 | Dithranol | 1,8,9-trihydroxyanthracene,cignoline,Anthralin | Others , DNA/RNA Synthesis |
Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. | |||
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T16674 | Pseudouridine | Endogenous Metabolite | |
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure. | |||
T17143 | Toyocamycin | Vengicide | Apoptosis , Others , IRE1 , Antibiotic , Antifungal |
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis. | |||
T4593 | ISOPIMPINELLIN | 5,8-Dimethoxypsoralen,4,9-Dimethoxypsoralen | Antiviral , DNA/RNA Synthesis , Parasite |
Isopimpinellin (4,9-Dimethoxypsoralen) is a natural product isolated from the roots of Pimpinella saxifrage with antiviral and antileishmanial activity. | |||
T9715 | Aplidine | SARS-CoV , DNA/RNA Synthesis | |
Aplidine possesses antiviral activity against SARS-CoV-2(IC90 = 0.88 nM). Aplidine is a potent anti-cancer agent by targeting eukaryotic translation elongation factor 1 Alpha 2(EEF1A2, Kd = 80 nM). | |||
T6194 | Fidaxomicin | Tiacumicin B,OPT-80,Clostomicin B1,PAR-101 | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Fidaxomicin (Tiacumicin B) is a semisynthetic macrolide antibiotic used to treat Clostridium difficile-associated diarrhea in adults. Fidaxomicin has minimal systemic absorption and has not been linked to serum enzyme el... | |||
T2998 | Dihydromyricetin | Ampelopsin,Ampeloptin | Influenza Virus , GABA Receptor , DNA/RNA Synthesis , mTOR , Autophagy |
Dihydromyricetin (Ampelopsin) is a natural antioxidant flavonoid from Ampelopsis grossedentata. Dihydromyricetin is a potent inhibitor of dihydropyrimidinase with an IC50 of 48 μM. Dihydromyricetin can activate autophagy... | |||
TN2132 | Quinizarin | 1,4-Dihydroxyanthraquinone | Others , DNA/RNA Synthesis , Antifungal |
Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product | |||
T13791 | N2-methylguanine | N2-methylguanine | DNA/RNA Synthesis , Endogenous Metabolite , Antibacterial |
N2-methylguanine (N2-methylguanine) is an endogenous methylated nucleoside found in human fluids and a modified nucleoside. | |||
T0064 | Adenine | Vitamin B4,6-Aminopurine | DNA/RNA Synthesis , Endogenous Metabolite , AChR |
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic... | |||
TWP2911 | Thymidine | 5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin | Others , DNA/RNA Synthesis , Endogenous Metabolite |
1. Thymidine (DThyd) overload due to Thymidine phosphorylase deficiency, and mitochondrial toxicity caused by antiviral Thymidine analogues. | |||
T7004 | Tubercidin | Sparsomycin A,7-Deazaadenosine | Influenza Virus , DNA/RNA Synthesis , Antibacterial , Antibiotic |
Tubercidin (Sparsomycin A), an adenosine analogue, is a nucleoside antibiotic. It is incorporated into DNA and inhibits polymerases, thereby inhibiting DNA replication and RNA and protein synthesis. This agent also exhib... | |||
T6116 | Bleomycin Sulfate | Blenoxane,NSC125066 | DNA/RNA Synthesis , Antibiotic |
Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity. | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
T6758 | Anisomycin | Flagecidin,NSC 76712,Wuningmeisu C | Apoptosis , DNA/RNA Synthesis , Antibacterial , Antibiotic , JNK |
Anisomycin (NSC-76712) is an antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. | |||
TN1097 | β-Boswellic acid | Beta-boswellic acid | Lipoxygenase , DNA/RNA Synthesis |
β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities. | |||
T3343 | 5-methoxyflavone | 5-methoxy-2-phenylchromen-4-one | DNA/RNA Synthesis |
5-methoxyflavone (5-methoxy-2-phenylchromen-4-one) is a naturally occurring, low molecular weight flavonoids compound that associated with a wide wariety of biological activities. | |||
T7174 | Urolithin A | Apoptosis , Reactive Oxygen Species , DNA/RNA Synthesis , Endogenous Metabolite , Autophagy , Drug Metabolite | |
Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties. | |||
TN2111 | Prunin | Naringenin 7-0-glucoside | Phosphatase , Anti-infection , Virus Protease |
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can... | |||
T1335 | Mycophenolic acid | Mycophenolate,RS-61443 | Apoptosis , Dehydrogenase , Endogenous Metabolite , Antibacterial , Antibiotic , UGT , Antifungal |
Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity. | |||
T0746 | Orotic acid | Vitamin B13,6-Carboxyuracil | Nucleoside Antimetabolite/Analog , Dehydrogenase , Endogenous Metabolite |
Orotic acid (Vitamin B13) is an intermediate product in pyrimidine metabolism. | |||
T38427 | DUTP trisodium | 2'-Deoxyuridine-5'-triphosphate trisodium salt,Deoxyuridine triphosphate | DNA/RNA Synthesis |
dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR. | |||
T6567 | Levofloxacin | Levaquin,Cravit,Tavanic,Fluoroquinolone,(-)-Ofloxacin | Topoisomerase , Antibacterial , Antibiotic |
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. | |||
T0062 | Folic acid | Folate,Vitamin B9,Pteroylglutamic acid,Vitamin M,Folacin | DNA/RNA Synthesis , Endogenous Metabolite |
Folic acid (Vitamin B9)(Vitamin M; Vitamin B9) is indispensable for the production and maintenance of new cells, for DNA/RNA synthesis. | |||
T1591L | Cytidine | Cytosine-1-β-D-ribofuranoside,Cytosine β-D-riboside | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
Cytidine (Cytosine-1-β-D-ribofuranoside) is a pyrimidine nucleoside comprised of a cytosine bound to ribose via a beta-N1-glycosidic bond. Cytidine is a precursor for uridine. Both cytidine and uridine are utilized in RN... | |||
T8186 | Xanthosine 5'-monophosphate sodium salt | XMP,L-XMP Sodium | Others |
Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism. | |||
T6225 | Adenine hydrochloride | Adenine HCl,6-Aminopurine hydrochloride | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry. | |||
T6369 | Adenine hemisulfate | Diadenine sulphate,Adenine sulfate,Adeninsulfat | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
T20945 | 2,4-D | Hedonal,Macondray,2,4-D acid,Chloroxone | DNA/RNA Synthesis |
2,4-Dichlorophenoxyacetic acid (Hedonal) is a synthetic auxin used as a plant growth regulator and also used as a supplement in plant cell culture media. It is an active ingredient in herbicides used to disrupts the acti... | |||
T1507 | Streptozocin | STZ,Streptozotocin,NSC-85998,U 9889 | DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy |
Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th... | |||
T0974 | Novobiocin Sodium | Albamycinsodium,Cathomycin,Albamycin | Potassium Channel , DNA gyrase , Topoisomerase , Antibacterial , Antibiotic , ABC , Autophagy |
Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound derived from Streptomyces niveus. It has a chemical structure sim... | |||
T3271 | Orotic acid zinc | Orotic acid zinc salt dihydrate,Zinc Orotate | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
Orotic acid zinc (Zinc Orotate) salt dihydrate is an intermediate product in pyrimidine synthesis. | |||
T3376 | Cynaroside | Luteoloside,Luteolin 7-β-D-Glucopyranoside,Luteolin 7-O-Glucoside,Luteolin 7-O-β-D-glucoside,Luteolin 7-glucoside | Others , Influenza Virus , DNA/RNA Synthesis |
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06071 | SARS-CoV-2 RNA-dependent RNA polymerase/RDRP Protein (His) | SARS-CoV-2 | Baculovirus-Insect Cells |
TMPY-03983 | CIRBP Protein, Human, Recombinant (His) | Human | E. coli |
CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular ... | |||
TMPH-00533 | T7 RNA polymerase Protein, Enterobacteria phage T7, Recombinant (His & Myc) | Escherichia phage T7 | E. coli |
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing... | |||
TMPY-03344 | LSM3 Protein, Human, Recombinant (His) | Human | E. coli |
LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-... | |||
TMPY-02441 | Alanyl-tRNA synthetase Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami... | |||
TMPJ-01258 | RNASE6 Protein, Human, Recombinant (His) | Human | Human Cells |
Ribonuclease K6 (RNASE6) is a secreted protein that belongs to the pancreatic ribonuclease family. Human RNASE6 is synthesized as a 150 amino acid precursor that contains a 23 amino acid signal sequence, and a 127 amino ... | |||
TMPJ-00574 | RNASE3 Protein, Human, Recombinant (His) | Human | Human Cells |
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a ... | |||
TMPH-02487 | CHRNA1 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
TMPY-04321 | CHRNA5 Protein, Human, Recombinant (His) | Human | HEK293 |
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in ... | |||
TMPY-02769 | RNASET2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
RNASET2 (ribonuclease T2) is an enzyme that belongs to the RNase T2 family. It is highly expressed in the temporal lobe and fetal brain. RNASET2 gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular r... | |||
TMPH-03620 | CHRNA1 Protein, Tetronarce californica, Recombinant (E. coli, His) | Torpedo californica | E. coli |
TMPH-00313 | TRNA (guanine-N(7)-)-methyltransferase Protein, Brugia malayi, Recombinant (His) | Brugia malayi | E. coli |
TMPH-00847 | 2-5A-dependent Rnase Protein, Human, Recombinant (Myc) | Human | E. coli |
TMPH-03621 | CHRNA1 Protein, Tetronarce californica, Recombinant (His) | Tetronarce californica | HEK293 |
TMPY-04946 | Alt a 1 Protein, Alternaria alternate, Recombinant | Alternaria alternate | E. coli |
TMPY-05305 | Alanyl-tRNA synthetase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Alanyl-tRNA synthetase (AARS) belongs to the family of ligases, specifically those forming carbon-oxygen bonds in aminoacyl-tRNA and related compounds. This enzyme participates in alanine and aspartate metabolism and ami... | |||
TMPH-00871 | CHRNA1 Protein, Human, Recombinant (His) | Human | E. coli |
TMPH-02486 | CHRNA1 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
TMPH-01779 | RNASE2 Protein, Human, Recombinant (His) | Human | E. coli |
TMPH-01457 | Human herpesvirus 6B (HHV-6 variant B) (strain Z29) mRNA export factor ICP27 homolog (His & Myc) | HHV-6B | E. coli |
TMPH-01762 | CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) | Human | E. coli |
TMPY-05775 | Human coronavirus (HCoV-229E) Nucleocapsid Protein (His) | HCoV-229E | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-05766 | Human coronavirus (HCoV-NL63) Nucleocapsid Protein (His) | HCoV-NL63 | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-03423 | MERS-CoV Nucleocapsid Protein (His) | MERS-CoV | Baculovirus-Insect Cells |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-05773 | Human coronavirus (HCoV-HKU1) Nucleocapsid Protein (His) | HCoV-HKU1 | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-05774 | Human coronavirus (HCoV-OC43) Nucleocapsid Protein (His) | HCoV-OC43 | E. coli |
Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both vi... | |||
TMPY-02130 | Argonaute-2 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-01186 | Argonaute-2 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Argonaute 2 (AGO2), also known as Eukaryotic translation initiation factor 2C2 (EIF2C2), belongs to the Argonaute family, AGO subfamily, which is a component of the RNA-induced silencing complex (RISC) and mediates small... | |||
TMPY-06059 | Influenza A H1N1 (A/Guangdong-Maonan/SWL1536/2019) Nucleoprotein/NP Protein (His) | H1N1 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-06057 | Influenza A H3N2 (A/Hong Kong/45/2019) Nucleoprotein/NP Protein (His) | H3N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-00560 | Influenza A H3N2 (A/Aichi/2/1968) Nucleoprotein/NP Protein (His) | H3N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-04274 | Influenza A H1N1 (A/Brevig Mission/1/1918) Nucleoprotein/NP Protein (His) | H1N1 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-01382 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Nucleoprotein/NP Protein (I116M, His) | H1N1 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-06062 | Influenza B (B/Phuket/3073/2013) Nucleoprotein/NP Protein (His) | Influenza B | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-06061 | Influenza B (B/Washington/02/2019) Nucleoprotein/NP Protein (His) | Influenza B | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-06058 | Influenza A H3N2 (A/Hong Kong/2671/2019) Nucleoprotein/NP Protein (His) | H3N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-04688 | Influenza B (B/Florida/4/2006) Nucleoprotein/NP Protein (His) | Influenza B | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-02876 | Influenza A H1N1 (A/California/07/2009) Nucleoprotein/NP Protein (His) | H1N1 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-06060 | Influenza A H1N1 (A/Hawaii/70/2019) Nucleoprotein/NP Protein (His) | H1N1 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-02617 | Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His) | H2N2 | Baculovirus-Insect Cells |
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter... | |||
TMPY-04870 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS1 protein (His) | ZIKV | HEK293 |
Zika virus NS1 antigen is one of seven non-structural proteins. NS1 is involved in RNA replication. The possible effects of NS1 on hosts include: localizes to host cell surface and secreted extracellularly, modulates sig... | |||
TMPY-02286 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His) | H1N1 | E. coli |
The Influenza virus matrix protein 1 (M1) is a matrix protein of the influenza virus. M1 protein has been shown to play a crucial role in virus replication, assembly, and budding. It forms a coat inside the viral envelop... | |||
TMPY-05822 | Hepatitis B Virus (HBV)(ayw/France/Tiollais/1979) Capsid protein (His) | HBV-D | E. coli |
Hepatitis B virus (HBV) capsid assembly is a critical step in the propagation of the virus and is mediated by the core protein. The first cytoplasmic step in the formation of an infectious HBV virion is the formation of ... | |||
TMPJ-00778 | HER2/ERBB2 Protein, Human, Recombinant (His) | Human | Human Cells |
Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPY-05024 | Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-NS5 protein (His) | ZIKV | Baculovirus-Insect Cells |
Zika virus NS5 is involved in methytransferase and RNA guanylytransferase activities and capping and synthesis of RNA. And, NS5 is also an RNA-dependent RNA polymerase. | |||
TMPH-00744 | CsrA Protein, E. coli, Recombinant | E. coli | E. coli |
Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II th... | |||
TMPH-02864 | Wnt1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Rna-dependent RNA polymerase part of the packaging complex that packages the viral RNA segments, replicate them into a double-stranded form and transcribe them. | |||
TMPY-05749 | SARS-CoV-2 NSP8 Protein (Avi) | SARS-CoV-2 | E. coli |
NSP8 is a nonstructural protein of coronavirus. NSP8 acts as a primase in RNA synthesis. NSP8 and NSP7 are essential co-factors of NSP12 (the catalytic subunit with RNA-dependent RNA polymerase activity) that can remarka... | |||
TMPH-01507 | HAPLN4 Protein, Human, Recombinant (His) | Human | E. coli |
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is ... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L1200 | Epigenetics Compound Library | 960 compounds | |
Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L8100 | Cell Cycle Compound Library | 695 compounds | |
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L1380 | Transcription Factor-Targeted Compound Library | 704 compounds | |
Well-chosen 704 compounds with unique structures targeting transcription factor; | |||
L5500 | Toxic Compound Library | 277 compounds | |
A unique collection of 277 toxic substances for high throughput screening (HTS) and high content screening (HCS); | |||
L1710 | Anti-COVID-19 Compound Library | 1160 compounds | |
A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; | |||
L3800 | NF-κB Signaling Compound Library | 740 compounds | |
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L9420 | Exosome Compound Library | 80 compounds | |
80 exosome-related compounds that can be used for high-throughput and high-content screening. |