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Search Results for " rip3 "

Targets

8

Compounds

1

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6904 Necrosulfonamide (E)-Necrosulfonamide MLK
(E)-Necrosulfonamide ((E)-Necrosulfonamide) is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during nec...
T11474 GSK-843 GSK'843 RIP kinase
GSK-843 (GSK'843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase.GSK-843 has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the ...
T11501 GSK840 GSK'840 RIP kinase
GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase activity (IC50: 0.3 nM).
T4074 GSK-872 GSK872,GSK'872,GSK2399872A RIP kinase
GSK-872 (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
T4074L GSK872 HCl(1346546-69-7 free base) GSK2399872A RIP kinase
GSK872 HCl(1346546-69-7 free base) (GSK2399872A) is an effective and specific RIP3 kinase inhibitor. It binds RIP3 kinase domain with high affinity (IC50: 1.8 nM) and inhibits kinase activity (IC50: 1.3 nM).
T6815 HS-1371 RIP kinase
HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.
T11484 GSK2593074A GSK'074 TNF , RIP kinase
GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.
T62569 RIPK3-IN-2
RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.
Cat No. Product Name Synonyms Targets
T3240 Citronellol dihydrogeraniol,(±)-β-Citronellol Reactive Oxygen Species
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00361 Pellino-1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. PELI1 may function to control inadvertent activation of RIP3, thus preventing aberrant ce...
TargetMol