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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14897 | CCG-63802 | GTPase | |
CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4. | |||
T14898 | CCG-63808 | GTPase | |
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM. | |||
T6434 | CCG-50014 | CCG 50014 | GTPase |
CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM. | |||
T68820 | CCG-4986 | ||
CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04058 | RGS5 Protein, Human, Recombinant (His) | Human | E. coli |
RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins ha... | |||
TMPY-02924 | RGS1 Protein, Human, Recombinant (His) | Human | E. coli |
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization o... | |||
TMPH-02020 | RGS17 Protein, Human, Recombinant (GST) | Human | E. coli |
RGS17 Protein, Human, Recombinant (GST) is expressed in E. coli. | |||
TMPH-02021 | RGS2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
RGS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-04409 | GRK6 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6, and GPRK6, is a lipid-anchor protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, and... | |||
TMPY-04555 | GRK5 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRKs specifically ... |