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Search Results for " rgs "

Targets

4

Compounds

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T14897 CCG-63802 GTPase
CCG-63802 is a reversible inhibitor of the regulator of G-protein signaling (RGS) protein and has the greatest potency at RGS4.
T14898 CCG-63808 GTPase
CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. CCG-63808 dose-dependently inhibits the TR-FRET signal between RGS4-AF488 and Tb-Gαo with IC50 values of 1.9 μM.
T6434 CCG-50014 CCG 50014 GTPase
CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.
T68820 CCG-4986
CCG-4986 is the first small molecule RGS inhibitor reported that directly bound to an RGS protein.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04058 RGS5 Protein, Human, Recombinant (His) Human E. coli
RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins ha...
TMPY-02924 RGS1 Protein, Human, Recombinant (His) Human E. coli
RGS1 (regulator of G-protein signaling 1) has been associated with multiple autoimmune disorders including type I diabetes. RGS1 desensitizes the chemokine receptors CCR7 and CXCR4 that are critical to the localization o...
TMPH-02020 RGS17 Protein, Human, Recombinant (GST) Human E. coli
RGS17 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-02021 RGS2 Protein, Human, Recombinant (His & SUMO) Human E. coli
RGS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-04409 GRK6 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
G protein-coupled receptor kinase 6, also known as G protein-coupled receptor kinase GRK6, GRK6, and GPRK6, is a lipid-anchor protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family, and...
TMPY-04555 GRK5 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRKs specifically ...
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