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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9673 | RET-IN-3 | c-RET | |
RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer. | |||
T8467 | RET V804M-IN-1 | RETV804M kinase inhibitor,LUN09945 | c-RET |
RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM). | |||
T40097 | RET-IN-4 | ||
RET-IN-4 is a highly effective and specific RET inhibitor that can be administered orally. It demonstrates remarkable potency, with IC50 values of 1.29 nM, 1.97 nM, and 0.99 nM for inhibiting RET variants including RET (... | |||
T69644 | DUN73423 | RET-IN-21 | c-RET |
DUN73423 (RET-IN-21) is a potent tyrosine kinase (RET) inhibitor with antitumour activity for the study of cancer. | |||
T16735 | RET-IN-1 | Others | |
RET-IN-1 is a RET kinase inhibitor (IC50s: 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively). | |||
T63772 | RET-IN-5 | ||
RET-IN-5 is a potent inhibitor of RET (IC50: 4.57 nM). | |||
T63877 | RET-IN-17 | ||
RET-IN-17 is a potent inhibitor of RET. RET-IN-17 has potential for studies of pain associated with IBS and other gastrointestinal disorders, as well as cancers with constitutive RET kinase activity. | |||
T79163 | RET-IN-24 | ||
RET-IN-24 (Compound 26) is a selective inhibitor of RET tyrosine kinase, demonstrating antitumor activity [1]. | |||
T78683 | RET-IN-22 | ||
RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-V804M. It demonstrates a highly selective inhibition profile ac... | |||
T63358 | RET-IN-15 | ||
RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. | |||
T73256 | RET-IN-16 | ||
RET-IN-16 is a potent, selective inhibitor of RET, exhibiting IC50 values of 3.98 nM for RET(WT), 8.42 nM for RET(M918T), 15.05 nM for RET(V804L), 7.86 nM for RET(V804M), 5.43 nM for RET-CCDC6, and 8.86 nM for RET-KIF5B,... | |||
T63249 | RET-IN-6 | ||
RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM). | |||
T63583 | RET-IN-11 | ||
RET-IN-11 is a potent and selective RET inhibitor that acts on RET (IC50: 6.20 nM) and RETV804M (IC50: 18.68 nM).RET-IN-11 induces apoptosis.RET-IN-11 exhibits anti-proliferative and migratory effects in LC-2/ad cells. R... | |||
T62877 | RET-IN-7 | ||
RET-IN-7 exhibits strong inhibitory effects against RET kinase in vitro and shows significant efficacy in treating RET-driven tumor xenografts in mice through multiple-day dosing. | |||
T81296 | RET-IN-26 | ||
RET-IN-26 (compound D5) is a kinase inhibitor that selectively targets the RET protein with an IC50 value of 0.33 μM [1]. | |||
T63183 | RET-IN-9 | ||
RET-IN-9 is a potent inhibitor of RET. RET kinase is a single-channel transmembrane receptor tyrosine kinase that plays an important role in the development of the kidney and enteric nervous system, as well as in the mai... | |||
T8222 | Selpercatinib | LOXO-292 | c-RET |
Selpercatinib (LOXO-292) is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively) | |||
T64103 | RET-IN-12 | ||
RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM). | |||
T79099 | RET-IN-23 | ||
RET-IN-23 (compound 17) is a potent, orally active inhibitor of RET, displaying IC50 values of 1.32 nM for RET-WT, 2.50 nM for RET-CCDC6, 6.54 nM for RET-V804L, 1.03 nM for RET-V804M, and 1.47 nM for RET-M918T. The compo... | |||
T63468 | RET-IN-14 | ||
RET-IN-14 is a potent inhibitor of RET, capable of acting on RET (WT) (IC50 < 0.51 nM), RET (G810R) (IC50: 9.3 nM), RET (V804M) (IC50: 1.3 nM), BTK (C481S) (IC50: 9.2 nM) and BTK (C481S) (IC50 : 15 nM). RET-IN-14 exhibit... | |||
T63837 | RET-IN-19 | ||
RET-IN-19 is a potent inhibitor of RET and exhibits anticancer effects on RET-wt (IC50: 6.8 nM) and RET V804M (IC50: 13.51 nM).RET-IN-19 can be used to study non-small cell lung cancer (NSCLC). | |||
T73248 | RET-IN-13 | ||
RET-IN-13, a quinoline-based compound, effectively inhibits the RET kinase, demonstrating IC50 values of 0.5 nM for RET (WT) and 0.9 nM for RET (V804M). It holds promise for research into tumors and intestinal diseases a... | |||
T73309 | RET-IN-20 | ||
RET-IN-20, a potent RET inhibitor, demonstrates an IC50 value of 13.7 nM and effectively decreases the expression of p-Ret and p-Shc protein. Moreover, it induces apoptosis and exhibits antiproliferative and anti-tumor a... | |||
T63782 | RET-IN-10 | ||
RET-IN-10 is a potent inhibitor of RET, in which RET loss-of-function mutations cause congenital megacolon and its gain-of-function mutations are associated with a variety of human tumors. RET-IN-10 has shown research po... | |||
T63230 | RET-IN-8 | ||
RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research. | |||
T79726 | RET-IN-25 | ||
RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximal inhibitory concentrations (IC50s) of 3.6 μM at 3 days and 3.0 μM... | |||
T67733 | BT44 | Others | |
BT44 is a novel, second-generation glial cell line_x0002_derived neurotropic factor mimetic with improved biological activity and is a lead compound for the treatment of neurodegenerative disorders. | |||
T10624 | BT-13 | c-RET | |
BT-13 is a selective agonist of glial cell line-derived neurotrophic factor (GDNF) receptor RET independently of GFLs. BT-13 promotes neurite growth from sensory neurons in vitro. | |||
T16923 | SPP-86 | c-RET | |
SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM. | |||
TQ0277 | Pralsetinib | Blu667 | c-RET |
Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion). | |||
T12598 | Pz-1 | VEGFR , c-RET | |
Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth. | |||
T2282 | RPI-1 | Others , Phospholipase , c-Met/HGFR , c-RET | |
RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor. | |||
T4301 | AD80 | Raf , c-RET , Src , S6 Kinase | |
AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity. | |||
T5491 | GSK3179106 | c-RET | |
GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM | |||
T7418 | BBT594 | NVP-BBT594 | c-RET |
BBT594 (NVP-BBT594)(NVP-BBT594) is a potent inhibitor of receptor tyrosine kinase RET,Treatment of cancer. | |||
T3065 | TG101209 | Apoptosis , FLT , c-RET , JAK , Autophagy | |
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM. | |||
T22349 | JNJ-38158471 | CS-2660 | VEGFR , c-RET , c-Kit |
JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM. | |||
T1792L | Regorafenib monohydrate | Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy | |
Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respect... | |||
T6920 | ON123300 | FGFR , c-RET , JAK , CDK , PDGFR , Src , AMPK | |
ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM). | |||
T8402 | Regorafenib Hydrochloride | BAY73-4506 hydrochloride | Raf , VEGFR , c-RET , PDGFR , Autophagy |
Regorafenib Hydrochloride (BAY73-4506 hydrochloride) is a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity | |||
T2032 | WHI-P180 | Janex 3 | EGFR , VEGFR , c-RET , CDK |
WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively. | |||
T0520 | Lenvatinib | E7080 | VEGFR , FGFR , c-RET , PDGFR , c-Kit |
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (... | |||
T1995 | Fedratinib | TG-101348,SAR 302503 | Apoptosis , FLT , c-RET , JAK |
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3. | |||
TD0081 | EDANS | EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid],1,5-EDANS,EDANS acid [5-((2-Aminoethyl)amino)napht | Others |
EDANS (EDANS acid [5-((2-Aminoethyl)amino)naphthalene-1-sulfonic acid]) is a novel and quenched fluorogenic substrate for assaying retroviral protease by resonance energy transfer (RET). | |||
T4053 | AST 487 | NVP-AST 487 | VEGFR , FLT , c-RET , Bcr-Abl , c-Kit |
AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. | |||
T2516 | Amuvatinib | MP470,HPK 56 | Apoptosis , FLT , c-Met/HGFR , c-RET , DNA/RNA Synthesis , PDGFR , c-Kit |
Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity. | |||
T8541 | Lenvatinib mesylate | E7080 (mesylate) | VEGFR , FGFR , c-RET , PDGFR , c-Kit |
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. | |||
T9251 | Fedratinib hydrochloride hydrate | TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate | Apoptosis , JAK |
Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor. | |||
T1792 | Regorafenib | BAY 73-4506,Fluoro-Sorafenib | Raf , VEGFR , c-RET , PDGFR , c-Kit , Autophagy |
Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orally active. Regorafenib has antitumor and anti-angiogenic activity. | |||
T6028 | PF 477736 | PF 00477736,PF-477736,PF-736,PF-00477736,PF477736 | c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase |
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6212 | Combretastatin A4 | CA4,CRC 87-09 | Microtubule Associated |
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). | |||
TN2148 | Retusin | 5-Hydroxy-3,7,3',4'-tetramethoxyflavone,Quercetin-3,7,3',4'-tetramethyl ether | ATPase , Free radical scavengers , Tyrosinase |
Retusin is derived from the leaves of Talinum triangulare. Retusin Retusin can be used in studies about acting as pre- and postemergent herbicides. | |||
T1611 | Isotretinoin | 13-cis-Retinoic acid | Retinoid Receptor , Endogenous Metabolite , Autophagy |
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs); activated RARs serve as transcription factors that promote cell differentiation and apoptosis. Isotretinoin is a naturall... | |||
T2565 | Hesperetin | Apoptosis , p38 MAPK , 5-HT Receptor , Autophagy , TGF-beta/Smad | |
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges. | |||
T1051 | Retinoic acid | Vitamin A acid,ATRA,all-trans-Retinoic acid,Tretinoin | Retinoid Receptor , Endogenous Metabolite , PPAR , Autophagy |
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα/β/γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferat... | |||
T4S1335 | Daphnoretin | Dephnoretin,Thymelol | Influenza Virus , Caspase , PKC |
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ... | |||
T6272 | Fosbretabulin Disodium | Combretastatin A4 Phosphate,CA 4DP,CA 4P,Combretastatin A4 disodium phosphate,Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium | Apoptosis , Microtubule Associated |
Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM). Fosbretabulin Disodium(Combretastatin A4 disodium phosphate) inhibit... | |||
T1183 | Retinol | all-trans-Retinol,Vitamin A,Vitamin A1,Alphalin | Others |
Retinol (Alphalin) and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune r... | |||
T0685 | Retinyl acetate | Vitamin A acetate,Retinyl (Retinol) Acetate,Retinol acetate | |
Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most importan... | |||
T1059 | Retinyl palmitate | Retinol palmitate,Vitamin A palmitate,Retinyl (Vitamin A) Palmitate | Others , Endogenous Metabolite |
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities. | |||
T7408 | All-trans-4-Oxoretinoic acid | all-trans 4-Keto Retinoic Acid | Endogenous Metabolite |
all-trans-4-Oxoretinoic acid (all-trans 4-Keto Retinoic Acid) is an active metabolite of vitamin A. | |||
TQ0280 | Feretoside | HSP | |
Feretoside is a natural product extracted from the barks of E. ulmoides. Feretoside shows inducible activity on the heat shock factor 1 (HSF1). | |||
TN7090 | Coretinphencone | Others | |
Coretinphencone is a natural product that is isolated from the buds of Coreopsis tinctoria Nutt. | |||
T0051 | Urethane | Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester | Chloride channel , GABA Receptor , Antibacterial , GluR , NMDAR , AChR , Parasite |
Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes. | |||
TN2244 | Sulfuretin | NF-κB , Autophagy | |
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr... | |||
T2842 | Tangeretin | NSC53909,Tangeritin,NSC618905 | Apoptosis , Gamma-secretase |
Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notc... | |||
T1330 | Acitretin | Ro 10-1670,Etretin | Apoptosis , Retinoid Receptor , Autophagy |
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. | |||
TJS2190 | Nordihydroguaiaretic acid | NDGA,Dihydronorguaiaretic Acid | Antioxidant , Ferroptosis , Lipoxygenase , Autophagy |
Nordihydroguaiaretic acid (NDGA) (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibito... | |||
TN7082 | Demethyldaphnoretin-7-O-glucoside | Others | |
Demethyldaphnoretin-7-O-glucoside is a natural product that is isolated from Daphne oleoides Schreber subsp. kurdica (DOK). In Turkish traditional medicine, the aerial parts of DOK have been used to treat malaria, rheuma... | |||
TN1733 | Hesperetin 7-O-glucoside | Anti-infection , Antibacterial , HMG-CoA Reductase | |
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inh... | |||
T8152 | 6-Demethoxytangeretin | MAPK , ALK | |
6-Demethoxytangeretin is a citrus flavonoid isolated from Citrus depressa. | |||
T5256 | All-trans-retinal | All trans-Retinal,Retinaldehyde,Vitamin A aldehyde | Others , Endogenous Metabolite |
All-trans-retinal (Vitamin A aldehyde) is a one of the major vitamin A metabolites in the retina. All-trans-RAL is regenerated to the visual chromophore, 11-cis-retinal in physiological conditions. | |||
T2924 | Phloretin | Dihydronaringenin,NSC 407292,RJC 02792 | SGLT , transporter , Endogenous Metabolite |
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leav... | |||
T4955 | Saponaretin | Isovitexin,Apigenin-6-C-glucoside | Apoptosis , Antioxidant |
saponaretin, an active component of many traditional Chinese medicines, shows various activities, such as anti-oxidant, anti-inflammatory, anti-alzheimer disease (AD) effects and so on. | |||
T35953 | All-trans-Anhydro Retinol | ||
All-trans-Anhydro Retinol (Anhydrovitamin A) is a Vitamin A metabolite commonly employed in the synthesis of multivitamin preparations[1]. | |||
TN6497 | Hesperetin-7-methyl ether | ||
Hesperetin-7-methyl ether is a natural prooduct from Citrus maxima. | |||
T81291 | Retrofractamide A | ||
Retrofractamide A, an amide constituent extracted from Piper chaba fruit, enhances adipogenesis in 3T3-L1 cells [1]. | |||
TN2147 | Retrorsine | P450 , OCT | |
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury. | |||
TN5536 | 2'-Hydroxyneophellamuretin | ||
2'-Hydroxyneophellamuretin is a natural product for research related to life sciences. The catalog number is TN5536 and the CAS number is 1396769-20-2. | |||
T34306 | Retusine | ||
Retusine is a compound extracted from the herb of Pogostemon cablin. | |||
T12667 | (Rac)-Hesperetin | Others | |
(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits potent inhibitory effects against human UGT activity, making it a broad-spectrum inhibitor. Furthermore,... | |||
TN4640 | Neophellamuretin | Others | |
Neophellamuretin is a natural product from Akschindlium godefroyanum (Kuntze) H. Ohashi. | |||
T28522 | Reticulol | ||
Reticulol is an isocoumarin derivative produced by certain species of Streptomyces. Reticulol inhibits cAMP phosphodiesterase (IC50 = 41 µM). Recticulol (M.W. 222.2) exhibits a potent in vitro cytotoxicity against the hu... | |||
TN4206 | Hesperetin 5-O-glucoside | Others | |
Hesperetin 5-O-glucoside has hypocholesterolemic effect. | |||
T40665 | Uvaretin | ||
Uvaretin and its derivative isouvaretin demonstrate potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM). | |||
TN3312 | 9-Angeloylretronecine N-oxide | Others | |
9-Angeloylretronecine N-oxide is a natural product for research related to life sciences. The catalog number is TN3312 and the CAS number is 27773-86-0. | |||
TN2145 | Retronecine | Others | |
Retronecine acts as the better competitor for the competitive inhibition of antibodies to Retronecine. | |||
T40695 | Isouvaretin | ||
Uvaretin and its derivative isouvaretin demonstrate potent antibacterial activity against B. subtilis (EC50: 8.7 μM) and S. epidermidis (IC50: 7.9 μM). | |||
TN4278 | Isodaphnoretin B | Others | |
Isodaphnoretin B is a natural product from Stellera chamaejasme. | |||
TN2146 | Retronecine N-oxide | Others | |
Retronecine N-oxide is a natural product | |||
T19169 | 9-cis-Retinal | Others | |
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and ma... | |||
TN1522 | Combretol | Antifection | |
Combretol has leishmanicidal activity, it showed moderate activity (growth inhibition 87.3 and 73.0 %, respectively, at 50 μM) against a multidrug-resistant L. tropica line. Combretol also shows weakly active cytotoxic a... | |||
TN5127 | Tereticornate A | Others | |
Tereticornate A is a natural product of Eucalyptus, Myrtaceae. The catalog number is TN5127 and the CAS number is 149751-81-5. Tereticornate A can be used as a reference standard. | |||
TN4889 | (R)-Reticuline | NADPH-oxidase | |
(R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids. | |||
TN4930 | Rutaretin | Others | |
Rutaretin is a natural product of Ruta, Rutaceae. The catalog number is TN4930 and the CAS number is 13895-92-6. Rutaretin can be used as a reference standard. | |||
TN3221 | 7-Angeloylretronecine | Antifection | |
7-Angeloylretronecine may have antibacterial effects. | |||
T28021 | Meso-Dihydroguaiaretic acid | ||
meso-Dihydroguaiaretic acid is an LXR-α antagonist, it inhibits hepatic lipid accumulation by activating AMP-activated protein kinase in human HepG2 cells. | |||
TN1581 | Dihydroguaiaretic acid | COX , DNA/RNA Synthesis | |
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress. | |||
T83917 | 6-O-Methylreticulol | 8-hydroxy-6,7-dimethoxy-3-methyl Isocoumarin | |
6-O-Methylreticulol, an isocoumarin derivative and fungal metabolite identified in S. mobaraensis, exhibits the characteristic structural features of its class. | |||
T79973 | Dehydrodiscretamine chloride | ||
Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM, respectively. It also possesses antioxidant activity and is ut... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02270 | RET Protein, Human, Recombinant (His) | Human | HEK293 |
RET proto-oncogene, also known as RET, is a cell-surface molecule that transduce signals for cell growth and differentiation. It contains 1 cadherin domain and 1 protein kinase domain. RET proto-oncogene belongs to the p... | |||
TMPY-04418 | RET Protein, Human, Recombinant (aa 658-1114, His & GST) | Human | Baculovirus-Insect Cells |
RET proto-oncogene, also known as RET, is a cell-surface molecule that transduce signals for cell growth and differentiation. It contains 1 cadherin domain and 1 protein kinase domain. RET proto-oncogene belongs to the p... | |||
TMPJ-00290 | GFR Alpha-2/GFRA2 Protein, Human, Recombinant (hFc & His) | Human | Human Cells |
GDNF family receptor alpha-2 is a glycosylphosphatidylinosito l (GPI)-linked cell surface receptor. It is part of the GDNF receptor family. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two s... | |||
TMPY-01756 | Transthyretin Protein, Human, Recombinant (His) | Human | HEK293 |
Prealbumin/Transthyretin, also known as ATTR, Prealbumin, TTR and PALB, is a secreted and cytoplasm protein that belongs to the Prealbumin / Transthyretin family. Prealbumin / Transthyretin is detected in serum and cereb... | |||
TMPK-01090 | Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in th... | |||
TMPY-02218 | CD20 Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features ... | |||
TMPY-04919 | Transthyretin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Prealbumin/Transthyretin, also known as ATTR, Prealbumin, TTR and PALB, is a secreted and cytoplasm protein that belongs to the Prealbumin / Transthyretin family. Prealbumin / Transthyretin is detected in serum and cereb... | |||
TMPY-03181 | Reticulocalbin 3/RCN3 Protein, Human, Recombinant (His) | Human | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... | |||
TMPY-00086 | Reticulocalbin 3/RCN3 Protein, Rat, Recombinant (His) | Rat | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... | |||
TMPK-00673 | SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu... | |||
TMPY-02226 | TNF alpha Protein, Ferret, Recombinant | Ferret | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological... | |||
TMPH-00436 | Calreticulin Protein, Cricetulus griseus, Recombinant (His) | Chinese hamster | Yeast |
Calreticulin Protein, Cricetulus griseus, Recombinant (His) is expressed in Yeast. | |||
TMPH-00319 | Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) | Burkholderia thailandensis | Yeast |
TMPH-03368 | SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-02182 | CD4 Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-03258 | Calreticulin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPY-03664 | IFN gamma Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPY-06327 | Calreticulin Protein, Human, Recombinant | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPY-03994 | SG3/Secretogranin 3 Protein, Human, Recombinant (His) | Human | HEK293 |
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ... | |||
TMPK-01122 | SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His) | Human | HEK293 |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regu... | |||
TMPH-00813 | Hepatitis E virus genotype 1 (HEV-1) Secreted protein ORF2 (His) | HEV-1 | Baculovirus |
Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked... | |||
TMPH-02068 | Secretogranin-1 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Secretogranin-1 Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPH-02242 | Transthyretin Protein, Human, Recombinant (hFc & Myc) | Human | HEK293 |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | |||
TMPH-02030 | Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) | Human | Yeast |
Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPH-00034 | ASFV (isolate Tick/South Africa/Pretoriuskop Pr4/1996) p12 Protein (His) | ASFV | in vitro E. coli expression system |
Virus attachment protein. | |||
TMPH-03105 | Calreticulin Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | Yeast |
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the mon... | |||
TMPY-02165 | CD8 alpha Protein, Ferret, Recombinant (His) | Ferret | HEK293 |
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp... | |||
TMPY-04672 | Reticulocalbin 3/RCN3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents th... | |||
TMPY-03259 | Calreticulin Protein, Human, Recombinant (His) | Human | HEK293 |
Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering... | |||
TMPY-03968 | Secretogranin II Protein, Human, Recombinant (His) | Human | HEK293 |
Kit ligand, also known as Hematopoietic growth factor KL, Mast cell growth factor, Steel factor, Stem cell factor, c-Kit ligand, Kitlg and KITL, is a single-pass type I membrane protein that belongs to the SCF family. KI... | |||
TMPY-06948 | Influenza A H1N1 (A/New Caledonia/20/1999) Hemagglutinin/HA-specific B cell probe (Y108F, and aa 339-342 SIQS→QRET, His & Avi), Biotinylated | H1N1 | Baculovirus-Insect Cells |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPK-00583 | TNF alpha Protein, Ferret, Recombinant (His) | Ferret | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system developm... | |||
TMPY-04675 | SG3/Secretogranin 3, Mouse, Recombinant (His) | Mouse | HEK293 |
SCG3, also known as secretogranin 3, is a member of the chromogranin/secretogranin family. Members of this family may serve as precursors for biologically active peptides. SCG3 is transported to secretory granules (SGs) ... | |||
TMPH-02034 | Retinoschisin Protein, Human, Recombinant (His) | Human | E. coli |
Retinoschisin Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02926 | TRET Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic c... | |||
TMPH-00757 | Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His) | Eschscholzia californica | E. coli |
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbo... | |||
TMPH-02027 | RETNLB Protein, Human, Recombinant (His) | Human | E. coli |
RETNLB Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-02947 | Transthyretin Protein, Mouse, Recombinant | Mouse | E. coli |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | |||
TMPH-02559 | Calreticulin Protein, Mouse, Recombinant (GST) | Mouse | E. coli |
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the mon... | |||
TMPH-02946 | Transthyretin Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. | |||
TMPH-02558 | Calreticulin Protein, Mouse, Recombinant (His) | Mouse | Yeast |
Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the mon... | |||
TMPH-02069 | Secretogranin-2 Protein, Human, Recombinant (GST & His) | Human | E. coli |
Secretogranin-2 Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPY-01458 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-00480 | NCAM1 Protein, Human, Recombinant (His) | Human | HEK293 |
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobuli... | |||
TMPH-03247 | Artemin Protein, Rat, Recombinant (His & Myc) | Rat | E. coli |
Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of... | |||
TMPY-05490 | GFR Alpha-1/GFRA1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-01391 | GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-03714 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
TMPY-02536 | GFR Alpha-3/GFRA3 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF... | |||
TMPY-01994 | GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His) | Rat | HEK293 |
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a... | |||
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Cat No. | Product Name | ||
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L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); |