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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7072 | Pitavastatin | ||
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC 50 of 5.8 nM. It also acts as an effic... | |||
T2534 | Pitavastatin calcium | P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,NK-104 | Apoptosis , Mitophagy , Endogenous Metabolite , HMG-CoA Reductase , Autophagy |
Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cyt... | |||
T12490 | Pitavastatin lactone | Others | |
Pitavastatin lactone is a major Pitavastatin metabolite in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes. | |||
T13131 | Tert-Buthyl Pitavastatin | HMG-CoA Reductase | |
tert-Buthyl Pitavastatin is Pitavastatin metabolite. Pitavastatin is a potent inhibitor of HMG-CoA reductase. | |||
T12488 | Pitavastatin D4 | NK-104 D4 | Others |
Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase. | |||
T68566 | Pitavastatin methyl ester | ||
Pitavastatin methyl ester is the methyl ester derivative of Pitavastatin -- a competitive inhibitor of HMG-CoA reductase and an anti-lipemic agent. | |||
T13380 | (Z)-Pitavastatin calcium | Others | |
(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase. | |||
T10132 | (3S,5S)-Pitavastatin calcium | Others | |
(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor. | |||
T10130 | (3S,5R)-Pitavastatin calcium | Others | |
(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor. | |||
T62598 | Pitavastatin sodium | ||
Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and a potent inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. pitavastatin sodium inhibit... |