plc — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23101	O-3M3FBS		Others
	Inactive analog of m-3M3FBS (PLC activator)		Others
T15044	D609		Apoptosis , Antioxidant
	D609 (Tricyclodecan-9-yl-Xanthogenate) has a wide range of biological activities including antioxidant, antiapoptotic, anticholinergic, antitumor, anti-inflammatory, antiviral, antiproliferative, and neuroprotective acti...		Apoptosis , Antioxidant
TQ0159	U-73343	U 73343	Phospholipase
	U-73343 is an inactive analog of U-73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor...		Phospholipase
T14903	CCT129957		Calcium Channel , Phospholipase
	CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.		Calcium Channel , Phospholipase
T6243	U-73122	U73122	Phospholipase , Ferroptosis , Lipoxygenase
	U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.		Phospholipase , Ferroptosis , Lipoxygenase
T8531	M-3M3FBS		Apoptosis , Phospholipase
	m-3M3FBS is a phospholipase C (PLC) activator.		Apoptosis , Phospholipase
T3132	SC66		Apoptosis , Akt
	SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).		Apoptosis , Akt
T70955	Vinaxanthone	SM-345431	Phospholipase , Antibacterial
	Vinaxanthone (SM-345431) is a small molecule compound derived from Penicillium chrysogenum that is a selective and potent semaphorin3A, phospholipase C (PLC), and FabI inhibitor, inhibiting semaphorin3A and FabI.Vinaxant...		Phospholipase , Antibacterial
T21815	ONO-RS-082		Others
	ONO-RS-082 is a Ca2+-independent phospholipase A2 inhibitor.		Others
T10115	3-Nitrocoumarin	3-nitrochromen-2-one	Phospholipase
	3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.		Phospholipase
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T74068	WH-15
	WH-15 is a fluorogenic phospholipase C (PLC) reporter, exhibiting Michaelis-Menten constant (Km) values of 49, 30, and 86.1 µM for PLC-γ1, PLC-δ1, and PLC-β2, respectively. It undergoes enzymatic cleavage in a cascade re...
T37434	P-Nitrophenylphosphorylcholine
	p-Nitrophenylphosphorylcholine is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can ...
T68752	Manoalide
	Manoalide, a sesterterpenoid compound, serves as a potent inhibitor of Phospholipase A2 (PLA2) and Phospholipase C (PLC). It exhibits anti-inflammatory and antibacterial properties.
TP1950	PEN(mouse)	PEN (mouse)
	Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide. Activates phospholipase C (PLC)-mediated signaling cascade in mouse hypothalamus.
T73812	Phosphatidylinositol 4,5-bisphosphate
	Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate), serving as a critical phospholipid in cell membranes, functions as a substrate for both phospholipase C (PLC) and phosphoinositide 3-...
TN2685	2,3,24-Trihydroxy-12-ursen-28-oic acid		Antifection
	2α,3α,24-Trihydroxyurs-12-en-28-oic acid, a triterpenoid phytoalexin, shows antifungal activity against the fungus mentioned. It also shows in vitro cytotoxic activity against tumor cell lines including PLC,Hep3B,HepG2,H...		Antifection
T35934	D-myo-Inositol-1,4,5-triphosphate (potassium salt)
	D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 rece...
T6345	Tirbanibulin	KX2-391,KX-01	Microtubule Associated , Src
	Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of colon, pancreatic, prostate and breast cancer. It is a substrate-targeted kinase inhibit...		Microtubule Associated , Src
T35938	D-myo-Inositol-4-phosphate (ammonium salt)
	D-myo-Inositol-4-phosphate (Ins(4)P1) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied I...