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Search Results for " nox "

Targets

303

Compounds

20

Natural Products

9

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T83972 NOX-6-18 GPR132 antagonist 1,GPR132-B-160 GPR
NOX-6-18 (GPR132-B-160) is a highly potent and selective GPR132 antagonist with insulinotropic activity that modulates macrophage reprogramming in pancreatic islets and reduces weight gain.
T33716 Norathiol NOX 100,NOX100,NOX-100
Norathiol(NOX-100) is nitric oxide (NO) scavenging agent that may be used to prevent hypotension during hemodialysis and septic shock.
T4359 VAS2870 NADPH
VAS2870 is an inhibitor of NADPH oxidase (NOX).
T8107 GLX351322 NADPH-oxidase , NADPH
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM.
T15433 GSK2795039 Apoptosis , Reactive Oxygen Species , ROS , NADPH
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays).
T22990 ML-090 Fluoflavine NADPH-oxidase , Others
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).
T68796 Thr101
Thr101, also known as NOX Inhibitor VII, is a dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9. Thr101 is also a NOX inhibitor.
T6099 Setanaxib GKT137831 NADPH-oxidase , Ferroptosis , NADPH
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.
T7191 Diphenyleneiodonium chloride DPI NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity.
T8408 GKT136901 AK120765 NADPH-oxidase , NADPH
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite
T10353 APX-115 free base Ewha-18278 free base NADPH-oxidase , NADPH
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid...
T3263 (6R,7S)-Cefminox sodium heptahydrate Meicelin,Cefminox Sodium,Alteporina,Tencef Antibiotic
(6R,7S)-Cefminox sodium heptahydrate (Meicelin) is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria.
T66390 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.
T7804 Garenoxacin mesylate hydrate Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate) Antibacterial
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains.
T2222 Carbinoxamine Maleate Salt Lergefin,CarbinoxaMine Maleate Histamine Receptor
Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties.
T20824 Cyanox CY 1790 Lowinox 1790,Irganox 3790,Antioxidant 1790,Irganox-3790,DN 90 Others
Cyanox CY 1790 (Irganox-3790) is an agent with antioxidant activity.
T1639 Amlexanox CHX3673,Amoxanox,AA673 IL Receptor , FGFR , Others , IκB/IKK
Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexan...
T25944 Phenoxyacetone NSC-1876,NSC 1876,NSC1876 Others
Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase.
T7153 Vanoxerine dihydrochloride GBR-12909 dihydrochloride,I893 dihydrochloride Dopamine Receptor
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM)
TP1886L1 NoxA1ds acetate(1435893-78-9 free base) NADPH-oxidase
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col...
T0992 Carbenoxolone disodium Biogastrone,Duogastrone,Bioral Gap Junction Protein
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ...
T22678 3,5-Bis(4-nitrophenoxy)benzoic acid Compound W Gamma-secretase
3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is an inhibitor of γ-secretase. It also causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25).
T50115 3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride Others
3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride is a synthetic compound belonging to the class of azabicyclooctanes. It is a potent and selective agonist of the dopamine D2 receptor and is widely used to study the mech...
T22424 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea Apoptosis , STAT
SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca...
T1190 Cefmenoxime hydrochloride Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride Antibacterial , Antibiotic , Antifection
Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganis...
T7843 4-phenoxypiperidine Others
4-phenoxypiperidines with muscle relaxant and anticonvulsant activities.
T0451 Minoxidil U10858 Potassium Channel , COX
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects.
T27417L Glutathione arsenoxide hydrochloride GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base) Apoptosis , AChR
Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride ta...
T33479 Monoxerutin Z 12007
Monoxerutin is a flavonol.
T7564 Chlorphenoxamine Contristamine Histamine Receptor
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.
T19805 Benoxacor BRN-4190275,BRN 4190275,BRN4190275 Others
Benoxacor (BRN-4190275) is an inert agricultural chemical. Benoxacor acts as an herbicide safener to protect crops from herbicide toxicity.
T16961 Supinoxin RX-5902 Apoptosis , DNA/RNA Synthesis
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50...
T0717 Enoxacin hydrate CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T5200 Indirubin-3'-monoxime Indirubin-3'-oxime GSK-3 , Lipoxygenase , CDK
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E).
T3431 Pardoprunox hydrochloride SLV-308 hydrochloride,DU-126891 hydrochloride Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept...
T19633 Ionox 330 Antioxidant 40,BRN 2034522,Ahydol,Antioxidant 330,AO-40 Others
Ionox 330 (Ahydol) is an alkylphenol compound used as an antioxidant.
T0917 Sulfaquinoxaline sodium salt SQ-Na,Sulfaquinoxaline sodium Antibacterial , Antibiotic , Parasite
Sulfaquinoxaline sodium salt (SQ-Na) is a veterinary broad-spectrum antimicrobial agent with antigram-negative and gram-positive activity.Sulfaquinoxaline can be used to prevent coccidiosis and bacterial infections.
T7902 Ozenoxacin T-3912 Antibacterial
Ozenoxacin (T-3912) is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections.
T20293 Phenoxyethanol NSC 1864,NSC-1864,NSC1864 Others , Antibacterial
Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.
T68166L Traxanox TFA Traxanox TFA(58712-69-9 Free base) Others
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition...
T0274 Cinoxacin Compound 64716 Topoisomerase , Antibacterial , Antibiotic
Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics. Its activity was similar to oxolinic acid and nalidixic acid.
T50072 3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride Others
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds.
T14955 Chlorthenoxazine Chlorethylbenzmethoxazone Immunology/Inflammation related
Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.
T1158 Phenoxybenzamine hydrochloride NCI-c01661,NSC 37448,Phenoxybenzamine HCl CaMK , Adrenergic Receptor
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non...
T8135 Minoxidil sulfate Minoxidil sulphate,U-58838 Potassium Channel
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil.
T68166 Traxanox Others
Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti...
T9872 Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- Others
Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- is a compound used for antiviral activity determinations.
T0717L Enoxacin NSC 629661,AT 2266,Pd107779,CI 919 DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
T1177 Sulfaquinoxaline Avicocid,Sulphaquinoxaline,Sulfabenzpyrazine Others , Antibacterial , Antibiotic , Parasite
Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.
T20076 Irganox 1010 Dovernox 10 Others
Irganox 1010 (Dovernox 10) is an agent of antioxidant.

Compounds

NOX-6-18
T83972
Synonym: GPR132 antagonist 1,GPR132-B-160
Target: GPR
Norathiol
T33716
Synonym: NOX 100,NOX100,NOX-100
Target:
VAS2870
T4359
Synonym:
Target: NADPH
GLX351322
T8107
Synonym:
Target: NADPH-oxidase, NADPH
GSK2795039
T15433
Synonym:
Target: Apoptosis, Reactive Oxygen Species, ROS, NADPH
ML-090
T22990
Synonym: Fluoflavine
Target: NADPH-oxidase, Others
Thr101
T68796
Synonym:
Target:
Setanaxib
T6099
Synonym: GKT137831
Target: NADPH-oxidase, Ferroptosis, NADPH
Diphenyleneiodonium chloride
T7191
Synonym: DPI
Target: NOS, Reactive Oxygen Species, NADPH, TRP/TRPV Channel
GKT136901
T8408
Synonym: AK120765
Target: NADPH-oxidase, NADPH
APX-115 free base
T10353
Synonym: Ewha-18278 free base
Target: NADPH-oxidase, NADPH
(6R,7S)-Cefminox sodium heptahydrate
T3263
Synonym: Meicelin,Cefminox Sodium,Alteporina,Tencef
Target: Antibiotic
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
T66390
Synonym:
Target:
Garenoxacin mesylate hydrate
T7804
Synonym: Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate)
Target: Antibacterial
Carbinoxamine Maleate Salt
T2222
Synonym: Lergefin,CarbinoxaMine Maleate
Target: Histamine Receptor
Cyanox CY 1790
T20824
Synonym: Lowinox 1790,Irganox 3790,Antioxidant 1790,Irganox-3790,DN 90
Target: Others
Amlexanox
T1639
Synonym: CHX3673,Amoxanox,AA673
Target: IL Receptor, FGFR, Others, IκB/IKK
Phenoxyacetone
T25944
Synonym: NSC-1876,NSC 1876,NSC1876
Target: Others
Vanoxerine dihydrochloride
T7153
Synonym: GBR-12909 dihydrochloride,I893 dihydrochloride
Target: Dopamine Receptor
NoxA1ds acetate(1435893-78-9 free base)
TP1886L1
Synonym:
Target: NADPH-oxidase
Carbenoxolone disodium
T0992
Synonym: Biogastrone,Duogastrone,Bioral
Target: Gap Junction Protein
3,5-Bis(4-nitrophenoxy)benzoic acid
T22678
Synonym: Compound W
Target: Gamma-secretase
3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride
T50115
Synonym:
Target: Others
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
T22424
Synonym:
Target: Apoptosis, STAT
Cefmenoxime hydrochloride
T1190
Synonym: Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride
Target: Antibacterial, Antibiotic, Antifection
4-phenoxypiperidine
T7843
Synonym:
Target: Others
Minoxidil
T0451
Synonym: U10858
Target: Potassium Channel, COX
Glutathione arsenoxide hydrochloride
T27417L
Synonym: GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)
Target: Apoptosis, AChR
Monoxerutin
T33479
Synonym: Z 12007
Target:
Chlorphenoxamine
T7564
Synonym: Contristamine
Target: Histamine Receptor
Benoxacor
T19805
Synonym: BRN-4190275,BRN 4190275,BRN4190275
Target: Others
Supinoxin
T16961
Synonym: RX-5902
Target: Apoptosis, DNA/RNA Synthesis
Enoxacin hydrate
T0717
Synonym: CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate
Target: DNA gyrase, DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic
Indirubin-3'-monoxime
T5200
Synonym: Indirubin-3'-oxime
Target: GSK-3, Lipoxygenase, CDK
Pardoprunox hydrochloride
T3431
Synonym: SLV-308 hydrochloride,DU-126891 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Ionox 330
T19633
Synonym: Antioxidant 40,BRN 2034522,Ahydol,Antioxidant 330,AO-40
Target: Others
Sulfaquinoxaline sodium salt
T0917
Synonym: SQ-Na,Sulfaquinoxaline sodium
Target: Antibacterial, Antibiotic, Parasite
Ozenoxacin
T7902
Synonym: T-3912
Target: Antibacterial
Phenoxyethanol
T20293
Synonym: NSC 1864,NSC-1864,NSC1864
Target: Others, Antibacterial
Traxanox TFA
T68166L
Synonym: Traxanox TFA(58712-69-9 Free base)
Target: Others
Cinoxacin
T0274
Synonym: Compound 64716
Target: Topoisomerase, Antibacterial, Antibiotic
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride
T50072
Synonym:
Target: Others
Chlorthenoxazine
T14955
Synonym: Chlorethylbenzmethoxazone
Target: Immunology/Inflammation related
Phenoxybenzamine hydrochloride
T1158
Synonym: NCI-c01661,NSC 37448,Phenoxybenzamine HCl
Target: CaMK, Adrenergic Receptor
Minoxidil sulfate
T8135
Synonym: Minoxidil sulphate,U-58838
Target: Potassium Channel
Traxanox
T68166
Synonym:
Target: Others
Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]-
T9872
Synonym:
Target: Others
Enoxacin
T0717L
Synonym: NSC 629661,AT 2266,Pd107779,CI 919
Target: DNA/RNA Synthesis, Topoisomerase, Antibacterial, Antibiotic
Sulfaquinoxaline
T1177
Synonym: Avicocid,Sulphaquinoxaline,Sulfabenzpyrazine
Target: Others, Antibacterial, Antibiotic, Parasite
Irganox 1010
T20076
Synonym: Dovernox 10
Target: Others
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
T5S0658 Corynoxine Autophagy
Corynoxine is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
T6S0654 Isocorynoxeine 7-Isocorynoxeine 5-HT Receptor
1. Isocorynoxeine (7-Isocorynoxeine) shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect ...
T0073 Octinoxate 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,Octyl methoxycinnamate Others
Octinoxate (Octyl 4-methoxycinnamate) is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage,primarily as an ingredient in some sunscreens and lip balms. It is also...
TN1527 (-)-Corynoxidine Corynoxidine Antibacterial , AChE , Antifection
(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus strains in di...
T6S0655 Corynoxeine ERK
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.
T7932 [(2-Methoxyphenoxy)Methyl]Oxirane Others
[(2-Methoxyphenoxy)Methyl]Oxirane is a natural product.
TN3110 5-Geranoxy-7-methoxycoumarin Anti-infection , Antibacterial , Antifungal
5-Geranoxy-7-methoxycoumarin shows antifungal activity.
T1468 Lornoxicam Ro 13-9297,Chlortenoxicam,TS110 COX , Endogenous Metabolite
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co...
T19091 2-(2',3',4'-Trihydroxybutyl)quinoxaline Others
2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite.
T81458 Pinofuranoxin A
Pinofuranoxin A effectively halts the proliferation of Athelia rolfsii and Phytophthora cambivora.
TN3801 Methoxyphenoxy]oxane-3,4,5-triol Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside Others
Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov.
T10010 1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol Others
1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an endogenous metabolite.
T5143 Corynoxine hydrochloride(6877-32-3(free base)) Autophagy
Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
T7732 Carbenoxolone Biogastrone,Carbenoxolona,Carbenoxolone,Bioral Dehydrogenase , Gap Junction Protein
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease.
T35359 3-Phenoxybenzoic acid 3-Phenoxybenzoic acid,m-phenoxybenzoic acid,3-PBA Others
3-Phenoxybenzoic acid is a natural product for research related to life sciences. The catalog number is T35359 and the CAS number is 3739-38-6.
TQ0258 Corynoxine B Autophagy
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
TN1607 Epicorynoxidine Others
Epicorynoxidine is an alkaloid derived from the herbs of Corydalis tashiroi.
T75438 Corynoxine hydrochloride
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid extracted from the hooks of Uncaria macrophylla, functions as a natural autophagy enhancer. It facilitates the removal of alpha-synuclein by activating the Akt/mT...
T3834 8-Epideoxyloganic acid ROS , Immunology/Inflammation related
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl...
T3S1416 Decursin Decursinol angelate,(+)-Decursin Apoptosis , PKC
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ...

Natural Products

Corynoxine
T5S0658
Synonym:
Target: Autophagy
Isocorynoxeine
T6S0654
Synonym: 7-Isocorynoxeine
Target: 5-HT Receptor
Octinoxate
T0073
Synonym: 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,Octyl methoxycinnamate
Target: Others
(-)-Corynoxidine
TN1527
Synonym: Corynoxidine
Target: Antibacterial, AChE, Antifection
Corynoxeine
T6S0655
Synonym:
Target: ERK
[(2-Methoxyphenoxy)Methyl]Oxirane
T7932
Synonym:
Target: Others
5-Geranoxy-7-methoxycoumarin
TN3110
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
Lornoxicam
T1468
Synonym: Ro 13-9297,Chlortenoxicam,TS110
Target: COX, Endogenous Metabolite
2-(2',3',4'-Trihydroxybutyl)quinoxaline
T19091
Synonym:
Target: Others
Pinofuranoxin A
T81458
Synonym:
Target:
methoxyphenoxy]oxane-3,4,5-triol
TN3801
Synonym: Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside
Target: Others
1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
T10010
Synonym:
Target: Others
Corynoxine hydrochloride(6877-32-3(free base))
T5143
Synonym:
Target: Autophagy
Carbenoxolone
T7732
Synonym: Biogastrone,Carbenoxolona,Carbenoxolone,Bioral
Target: Dehydrogenase, Gap Junction Protein
3-Phenoxybenzoic acid
T35359
Synonym: 3-Phenoxybenzoic acid,m-phenoxybenzoic acid,3-PBA
Target: Others
Corynoxine B
TQ0258
Synonym:
Target: Autophagy
Epicorynoxidine
TN1607
Synonym:
Target: Others
Corynoxine hydrochloride
T75438
Synonym:
Target:
8-Epideoxyloganic acid
T3834
Synonym:
Target: ROS, Immunology/Inflammation related
Decursin
T3S1416
Synonym: Decursinol angelate,(+)-Decursin
Target: Apoptosis, PKC

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01276 ENOX1 Protein, Human, Recombinant (His) Human E. coli
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol intercha...
TMPJ-00848 NCF1 Protein, Human, Recombinant (His) Human E. coli
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem...
TMPH-01278 ENOX2 Protein, Human, Recombinant (His & Myc) Human E. coli
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ...
TMPH-01277 ENOX2 Protein, Human, Recombinant Human E. coli
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ...
TMPH-01746 NOX4 Protein, Human, Recombinant (E. coli, His) Human E. coli
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-00361 Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) Centruroides noxius Yeast
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals.
TMPH-01745 NOX4 Protein, Human, Recombinant (Cell-Free, His) Human in vitro E. coli expression system
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor...
TMPH-01744 NOX1 Protein, Human, Recombinant (His) Human in vitro E. coli expression system
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-d...
TMPY-02391 SUMO1 Protein, Human, Recombinant (His) Human E. coli
Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific pro...
Cat No. Product Name
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
TargetMol