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Cat No. | Product Name | Synonyms | Targets |
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T83972 | NOX-6-18 | GPR132 antagonist 1,GPR132-B-160 | GPR |
NOX-6-18 (GPR132-B-160) is a highly potent and selective GPR132 antagonist with insulinotropic activity that modulates macrophage reprogramming in pancreatic islets and reduces weight gain. | |||
T33716 | Norathiol | NOX 100,NOX100,NOX-100 | |
Norathiol(NOX-100) is nitric oxide (NO) scavenging agent that may be used to prevent hypotension during hemodialysis and septic shock. | |||
T4359 | VAS2870 | NADPH | |
VAS2870 is an inhibitor of NADPH oxidase (NOX). | |||
T8107 | GLX351322 | NADPH-oxidase , NADPH | |
GLX351322 is NADPH Oxidase 4 Inhibitor with IC50 of 5 μM. | |||
T15433 | GSK2795039 | Apoptosis , Reactive Oxygen Species , ROS , NADPH | |
GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 decreases apoptosis. GSK2795039 is an inhibitor of NADPH oxidase 2 (NOX2) (pIC50: 6 in different cell-free assays). | |||
T22990 | ML-090 | Fluoflavine | NADPH-oxidase , Others |
ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM). | |||
T68796 | Thr101 | ||
Thr101, also known as NOX Inhibitor VII, is a dose-dependent inhibitor of HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9. Thr101 is also a NOX inhibitor. | |||
T6099 | Setanaxib | GKT137831 | NADPH-oxidase , Ferroptosis , NADPH |
Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor. | |||
T7191 | Diphenyleneiodonium chloride | DPI | NOS , Reactive Oxygen Species , NADPH , TRP/TRPV Channel |
Diphenyleneiodonium chloride (DPI)(DPI) is an irreversible inhibitor of iNOS and eNOS (IC50 values of 50 nM and 0.3 μM, respectively),and displays broad-spectrum bactericidal activity. | |||
T8408 | GKT136901 | AK120765 | NADPH-oxidase , NADPH |
GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite | |||
T10353 | APX-115 free base | Ewha-18278 free base | NADPH-oxidase , NADPH |
APX-115 free base (Ewha-18278 free base) (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4). APX-115 effectively prevents kid... | |||
T3263 | (6R,7S)-Cefminox sodium heptahydrate | Meicelin,Cefminox Sodium,Alteporina,Tencef | Antibiotic |
(6R,7S)-Cefminox sodium heptahydrate (Meicelin) is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. | |||
T66390 | 4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide | ||
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil. | |||
T7804 | Garenoxacin mesylate hydrate | Garenoxacin mesylate [USAN],BMS284756 (Mesylate hydrate) | Antibacterial |
Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains. | |||
T2222 | Carbinoxamine Maleate Salt | Lergefin,CarbinoxaMine Maleate | Histamine Receptor |
Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties. | |||
T20824 | Cyanox CY 1790 | Lowinox 1790,Irganox 3790,Antioxidant 1790,Irganox-3790,DN 90 | Others |
Cyanox CY 1790 (Irganox-3790) is an agent with antioxidant activity. | |||
T1639 | Amlexanox | CHX3673,Amoxanox,AA673 | IL Receptor , FGFR , Others , IκB/IKK |
Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexan... | |||
T25944 | Phenoxyacetone | NSC-1876,NSC 1876,NSC1876 | Others |
Phenoxyacetone (NSC-1876) is an inhibitor of acetylcholinesterase. | |||
T7153 | Vanoxerine dihydrochloride | GBR-12909 dihydrochloride,I893 dihydrochloride | Dopamine Receptor |
Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a potent inhibitor that blocks dopamine uptake (IC50 : 1-51 nM) | |||
TP1886L1 | NoxA1ds acetate(1435893-78-9 free base) | NADPH-oxidase | |
NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col... | |||
T0992 | Carbenoxolone disodium | Biogastrone,Duogastrone,Bioral | Gap Junction Protein |
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... | |||
T22678 | 3,5-Bis(4-nitrophenoxy)benzoic acid | Compound W | Gamma-secretase |
3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is an inhibitor of γ-secretase. It also causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). | |||
T50115 | 3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride | Others | |
3-phenoxy-8-azabicyclo[3.2.1]octane hydrochloride is a synthetic compound belonging to the class of azabicyclooctanes. It is a potent and selective agonist of the dopamine D2 receptor and is widely used to study the mech... | |||
T22424 | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea | Apoptosis , STAT | |
SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca... | |||
T1190 | Cefmenoxime hydrochloride | Cefmenoxime hemihydrochloride,SCE-1365 hemihydrochloride | Antibacterial , Antibiotic , Antifection |
Cefmenoxime hydrochloride (Cefmenoxime hemihydrochloride) is a cephalosporin antibiotic that is administered intravenously or intramuscularly. It is active against most common gram-positive and gram-negative microorganis... | |||
T7843 | 4-phenoxypiperidine | Others | |
4-phenoxypiperidines with muscle relaxant and anticonvulsant activities. | |||
T0451 | Minoxidil | U10858 | Potassium Channel , COX |
Minoxidil (U10858) is an orally administered vasodilator with hair growth stimulatory and antihypertensive effects. | |||
T27417L | Glutathione arsenoxide hydrochloride | GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base) | Apoptosis , AChR |
Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride ta... | |||
T33479 | Monoxerutin | Z 12007 | |
Monoxerutin is a flavonol. | |||
T7564 | Chlorphenoxamine | Contristamine | Histamine Receptor |
Chlorphenoxamine (Contristamine) is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent. | |||
T19805 | Benoxacor | BRN-4190275,BRN 4190275,BRN4190275 | Others |
Benoxacor (BRN-4190275) is an inert agricultural chemical. Benoxacor acts as an herbicide safener to protect crops from herbicide toxicity. | |||
T16961 | Supinoxin | RX-5902 | Apoptosis , DNA/RNA Synthesis |
Supinoxin (RX-5902) is an orally active inhibitor of phosphorylated-p68 RNA helicase and a potent first-in-class anti-cancer agent. Supinoxin induces cell apoptosis and inhibits the growth of TNBC cancer cell lines (IC50... | |||
T0717 | Enoxacin hydrate | CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate | DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic |
Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent. | |||
T5200 | Indirubin-3'-monoxime | Indirubin-3'-oxime | GSK-3 , Lipoxygenase , CDK |
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E). | |||
T3431 | Pardoprunox hydrochloride | SLV-308 hydrochloride,DU-126891 hydrochloride | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept... | |||
T19633 | Ionox 330 | Antioxidant 40,BRN 2034522,Ahydol,Antioxidant 330,AO-40 | Others |
Ionox 330 (Ahydol) is an alkylphenol compound used as an antioxidant. | |||
T0917 | Sulfaquinoxaline sodium salt | SQ-Na,Sulfaquinoxaline sodium | Antibacterial , Antibiotic , Parasite |
Sulfaquinoxaline sodium salt (SQ-Na) is a veterinary broad-spectrum antimicrobial agent with antigram-negative and gram-positive activity.Sulfaquinoxaline can be used to prevent coccidiosis and bacterial infections. | |||
T7902 | Ozenoxacin | T-3912 | Antibacterial |
Ozenoxacin (T-3912) is a quinolone antibacterial. It shows potent activities against the main microorganisms isolated from soft tissue and skin infections. | |||
T20293 | Phenoxyethanol | NSC 1864,NSC-1864,NSC1864 | Others , Antibacterial |
Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds. | |||
T68166L | Traxanox TFA | Traxanox TFA(58712-69-9 Free base) | Others |
Traxanox TFA is an orally available diuretic. Traxanox TFA enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro. Traxanox TFA restores inhibition... | |||
T0274 | Cinoxacin | Compound 64716 | Topoisomerase , Antibacterial , Antibiotic |
Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics. Its activity was similar to oxolinic acid and nalidixic acid. | |||
T50072 | 3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride | Others | |
3-amino-1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]propan-1-one dihydrochloride is used in the synthesis of various compounds. | |||
T14955 | Chlorthenoxazine | Chlorethylbenzmethoxazone | Immunology/Inflammation related |
Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity. | |||
T1158 | Phenoxybenzamine hydrochloride | NCI-c01661,NSC 37448,Phenoxybenzamine HCl | CaMK , Adrenergic Receptor |
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non... | |||
T8135 | Minoxidil sulfate | Minoxidil sulphate,U-58838 | Potassium Channel |
Minoxidil sulfate (U-58838) is the active metabolite required to exert the vasodilatory and hair growing effects of minoxidil. | |||
T68166 | Traxanox | Others | |
Traxanox is an orally available diuretic.Traxanox enhances phagocytosis of yeast granules by mouse peritoneal macrophages or rat peritoneal polymorphonuclear leukocytes in vitro.Restorative effect of Traxanox on inhibiti... | |||
T9872 | Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- | Others | |
Acetic acid, 2-[4-[(2-ethyl-3-benzofuranyl)carbonyl]phenoxy]- is a compound used for antiviral activity determinations. | |||
T0717L | Enoxacin | NSC 629661,AT 2266,Pd107779,CI 919 | DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic |
Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid. | |||
T1177 | Sulfaquinoxaline | Avicocid,Sulphaquinoxaline,Sulfabenzpyrazine | Others , Antibacterial , Antibiotic , Parasite |
Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent. | |||
T20076 | Irganox 1010 | Dovernox 10 | Others |
Irganox 1010 (Dovernox 10) is an agent of antioxidant. |
Cat No. | Product Name | Synonyms | Targets |
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T5S0658 | Corynoxine | Autophagy | |
Corynoxine is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. | |||
T6S0654 | Isocorynoxeine | 7-Isocorynoxeine | 5-HT Receptor |
1. Isocorynoxeine (7-Isocorynoxeine) shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect ... | |||
T0073 | Octinoxate | 2-Ethylhexyl 4-methoxycinnamate,ethylhexyl methoxycinnamate,Octyl 4-methoxycinnamate,Octyl methoxycinnamate | Others |
Octinoxate (Octyl 4-methoxycinnamate) is used is in sunscreens and other cosmetics to absorb UV-B rays from the sun, protecting the skin from damage,primarily as an ingredient in some sunscreens and lip balms. It is also... | |||
TN1527 | (-)-Corynoxidine | Corynoxidine | Antibacterial , AChE , Antifection |
(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus strains in di... | |||
T6S0655 | Corynoxeine | ERK | |
1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty. | |||
T7932 | [(2-Methoxyphenoxy)Methyl]Oxirane | Others | |
[(2-Methoxyphenoxy)Methyl]Oxirane is a natural product. | |||
TN3110 | 5-Geranoxy-7-methoxycoumarin | Anti-infection , Antibacterial , Antifungal | |
5-Geranoxy-7-methoxycoumarin shows antifungal activity. | |||
T1468 | Lornoxicam | Ro 13-9297,Chlortenoxicam,TS110 | COX , Endogenous Metabolite |
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co... | |||
T19091 | 2-(2',3',4'-Trihydroxybutyl)quinoxaline | Others | |
2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite. | |||
T81458 | Pinofuranoxin A | ||
Pinofuranoxin A effectively halts the proliferation of Athelia rolfsii and Phytophthora cambivora. | |||
TN3801 | Methoxyphenoxy]oxane-3,4,5-triol | Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside | Others |
Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. | |||
T10010 | 1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol | Others | |
1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is an endogenous metabolite. | |||
T5143 | Corynoxine hydrochloride(6877-32-3(free base)) | Autophagy | |
Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. | |||
T7732 | Carbenoxolone | Biogastrone,Carbenoxolona,Carbenoxolone,Bioral | Dehydrogenase , Gap Junction Protein |
Carbenoxolone (Biogastrone) is an inhibitor of 11β-HSD and gap junction connexin channels. Carbenoxolone inhibits macrophage migration into atria and prevents the development of fatty liver disease. | |||
T35359 | 3-Phenoxybenzoic acid | 3-Phenoxybenzoic acid,m-phenoxybenzoic acid,3-PBA | Others |
3-Phenoxybenzoic acid is a natural product for research related to life sciences. The catalog number is T35359 and the CAS number is 3739-38-6. | |||
TQ0258 | Corynoxine B | Autophagy | |
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese). | |||
TN1607 | Epicorynoxidine | Others | |
Epicorynoxidine is an alkaloid derived from the herbs of Corydalis tashiroi. | |||
T75438 | Corynoxine hydrochloride | ||
Corynoxine hydrochloride, a tetracyclic oxindole alkaloid extracted from the hooks of Uncaria macrophylla, functions as a natural autophagy enhancer. It facilitates the removal of alpha-synuclein by activating the Akt/mT... | |||
T3834 | 8-Epideoxyloganic acid | ROS , Immunology/Inflammation related | |
8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibl... | |||
T3S1416 | Decursin | Decursinol angelate,(+)-Decursin | Apoptosis , PKC |
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01276 | ENOX1 Protein, Human, Recombinant (His) | Human | E. coli |
Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a protein disulfide-thiol intercha... | |||
TMPJ-00848 | NCF1 Protein, Human, Recombinant (His) | Human | E. coli |
Neutrophil cytosol factor 1( NCF1) is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is characterized as a multicomponent enzyme which is activated to produce superoxide anion. NCF2, NCF1, and a mem... | |||
TMPH-01278 | ENOX2 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPH-01277 | ENOX2 Protein, Human, Recombinant | Human | E. coli |
May be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P)H via hydroquinones to acceptors at the cell surface. Hydroquinone oxidase activity alternates with a ... | |||
TMPH-01746 | NOX4 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor... | |||
TMPH-00361 | Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His) | Centruroides noxius | Yeast |
Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. | |||
TMPH-01745 | NOX4 Protein, Human, Recombinant (Cell-Free, His) | Human | in vitro E. coli expression system |
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor... | |||
TMPH-01744 | NOX1 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-d... | |||
TMPY-02391 | SUMO1 Protein, Human, Recombinant (His) | Human | E. coli |
Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific pro... |
Cat No. | Product Name | ||
---|---|---|---|
L8700 | Ferroptosis Compound Library | 800 compounds | |
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; |