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Search Results for " ldl "

Targets

75

Compounds

22

Natural Products

76

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10063 LDL-IN-3 Antioxidant
LDL-IN-3 shows anti-atherosclerotic and antioxidant activities.
T4039 BIBB 515 Others
BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...
T9276 SBC-115337 Others , Serine/threonin kinase
SBC-115337 is a PCSK9 inhibitor.
T7832 Ibrolipim NO-1886 LPL Receptor
Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway.
T2626 SBC-115076 SBC115076 Others , Serine/threonin kinase
SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.
T2499 Torcetrapib CP-529414 CETP
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces...
T6690 T0901317 Apoptosis , FXR , Liver X Receptor , ROR
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).
T1928 Anacetrapib MK-0859 CETP
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th...
T4179 Probucol disuccinate LDL
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
T4058 R-IMPP Others , Serine/threonin kinase
R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin.
TP1881L1 Pep 2-8 ammonium salt(1541011-97-5 free base) Others
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
T67776 PCSK9-IN-11 Others
PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity. PCSK9-IN-11 shows inhibitory activity of PCSK9 transcription in HepG2 cells (IC50= 5.7 μM). PCSK9-IN-11 can increase LDL receptor (LDLR) protein l...
T9916 Alirocumab Others
Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.
T20887 Atorvastatin Sodium Lipitor LDL , Aquaporin , HMG-CoA Reductase
Atorvastatin Sodium (Lipitor) is a competitive inhibitor of HMG-CoA reductase and increases the expression of low density lipoprotein (LDL) receptors on hepatocytes. Atorvastatin Sodium treatment inhibits aquaporin 4 to ...
T27832 Lifibrol U 83860,K-12148,K-12.148,U-83860,K12148 Lipid
Lifibrol (U-83860) is an inhibitor of cholesterol synthesis.Lifibrol has anticholesterol and hypolipidemic properties and promotes the conversion of LDL Apo B-100 in patients with hypercholesterolemia and mixed hyperlipi...
T1771 Ro 48-8071 fumarate Others
Ro 48-8071 fumarate is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
T68042 CHF-4227 Chf4227,Chf 4227 Estrogen Receptor/ERR
CHF-4227 is a novel, potent and selective estrogen receptor modulator that reduces cholesterol and LDL cholesterol concentrations.
T76739 Bococizumab RN316,PF-04950615 Others
Bococizumab(PF-04950615) is a humanized mAb against PCSK9 and an inhibitor of the synthesis of PCSK9 in the liver that reduces the amount of low-density lipoprotein cholesterol (LDL-C) in the blood.Bococizumab is used to...
T0342 Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate) VEGFR , Others , Potassium Channel , LDL , Integrin , Gap Junction Protein , NADPH , Adrenergic Receptor , Autophagy
Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathom...
T38063 N-Acetyl lysyltyrosylcysteine amide Glutathione Peroxidase
N-Acetyl lysyltyrosylcysteine amide is a non-toxic myeloperoxidase (MPO) tripeptide inhibitor that is potent, reversible, and specific.N-Acetyl lysyltyrosylcysteine amide effectively inhibits MPO production in vivo. N-Ac...
T5360 Eprotirome KB2115 Thyroid hormone receptor(THR)
Eprotirome (KB2115), a synthetic thyroid hormone mimetic, is a thyroid hormone receptor agonist.
TP1111 Tirzepatide LY-3298176 Glucagon Receptor
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
T36013 Lysophosphatidylcholines ​Lyso-Lecithins (egg)
Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 position by phospholipase A2 (PLA2) or by lecithin-cholesterol acyltranferase (LCAT), which transfer...
TP1881 Pep2-8 Pep 2-8
Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
T70504 6,8-Diprenyleriodictyol
6,8-Diprenyleriodictyol is an antioxidant, which inhibits Cu(2+)-mediated oxidation of human low density lipoprotein (LDL).
T76377 Cdk2/Cyclin Inhibitory Peptide II
Cdk2/Cyclin Inhibitory Peptide II (Tat-LDL), a CDK2 inhibitor, kills U2OS osteosarcoma cells in a dose-dependent manner [1] .
T77144 Recaticimab
Recaticimab (SHR-1209) is a humanized monoclonal antibody that inhibits PCSK9 . Receticimab mediates the degradation of PCSK9 by binding to PCSK9, increasing the level of low-density lipoprotein (LDL) receptors on the su...
T74778 ASM-IN-1 Phospholipase
ASM-IN-1 is a potent, orally active inhibitor of acid sphingomyelinase (ASM) with an IC50 of 1.5 µM, demonstrating antiatherosclerotic and anti-inflammatory activity. It effectively reduces lipid plaques in the aortic ar...
T30111 AR 12465 AR-12465
AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human skin fibroblasts (HSF) and human hepatic cells (HEP G2).
T73008 PCSK9-IN-13
PCSK9-IN-13 is a potent PCSK9 inhibitor, which can antagonize low-density lipoprotein (LDL) receptor binding by binding to PCSK9, with an IC 50 of 537 nM .
T11386 Gemcabene calcium PD-72953 calcium Others
Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammator...
T76974 Tafolecimab
Tafolecimab (IBI-306) is a human lgG2 monoclonal antibody that specifically binds PCSK-9 and reduces LDL-C levels by inhibiting PCSK-9-mediated endocytosis of the LDL receptor, which in turn enhances clearance of LDL-C a...
T35404 (±)13-HODE cholesteryl ester
(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human mono...
T35405 (±)9-HODE cholesteryl ester
(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL. Later studies determined that 15-LO from rabbit reticulocytes and human monoc...
T74577 Milpocitide
Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1) [1] .
T3625 Bempedoic acid ETC1002,ESP-55016,ETC 1002,ETC-1002 ATP Citrate Lyase , AMPK
Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies. Bempedoic ...
T68695 (R)-Bambuterol
Bambuterol is a prodrug of β2-agonist commonly used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) with the advantage of once daily dosing and favorable side effect profile. Administration o...
T75537 N-Acetyldopamine dimer-2
N-Acetyldopamine dimer-2 (compound 2) is a N -acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibit...
T15561 Imanixil HOE-402(free base) Others
Imanixil is an inducer of the LDL receptor (LDLR) and it is also a potent cholesterol-lowering compound. It also inhibits very low density-lipoprotein (VLDL) production and consequently decreases atherosclerosis developm...
T79239 PCSK9-IN-19
PCSK9-IN-19 (Compound 1), a PCSK9 inhibitor, is utilized in researching the treatment of high LDL-cholesterol levels and the prevention of coronary artery disease [1].
T80658 Quercetin 7-glucuronide Quercetin 7-O-β-glucuronide Drug Metabolite
Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL oxidation [1].
T69408 GW590735 sodium
GW590735 is a potent and selective agonist of PPARα with an EC50 value of 4 nM for the expression a GAL4-responsive reporter gene and at least 500-fold selectivity versus PPARγ and PPARδ. GW590735 significantly increased...
T36727 9(S)-HODE
9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.[1],[2] It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL pa...
T71981 Gliclazide-d4
Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ...
T28080 Mocravimod KRP 203 free base,KRP-203,KRP203
Mocravimod is an agonist of sphingosine 1-phosphate receptor type 1. Mocravimod ameliorates atherosclerosis in LDL-R-/- mice. KRP-203 attenuates rat autoimmune myocarditis. KRP-203 combined with cyclosporine prolonged gr...
T62052 AMPK activator 6
AMPK activator 6 (Compound GC) activates the AMPK pathway and reduces lipid content in HepG2 and 3T3-L1 cells. AMPK activator 6 significantly suppresses the increase of total cholesterol (TC), low-density lipoprotein-C (...
T36171 KDdiA-PC
Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. Many of these substances were recently isolated and purified from oxLDL, and identified as ...
T77014 Frovocimab
Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9 . Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact...
T60764 PCSK9 modulator-4
PCSK9 modulator-4 (Compound 21) can be used in hyperlipidemia research that is a potent PCSK9 modulator (EC 50 = 0.15 nM). PCSK9 is a lowering low-density lipoprotein cholesterol (LDL-C) target that is recently validated...
T60541 PCSK9 modulator-2
PCSK9 modulator-2 (Compound 1) is a potent PCSK9 modulator (EC 50 = 202 nM) that has the potential to be used in hyperlipidemia research. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a recently validated ther...

Compounds

LDL-IN-3
T10063
Synonym:
Target: Antioxidant
BIBB 515
T4039
Synonym:
Target: Others
SBC-115337
T9276
Synonym:
Target: Others, Serine/threonin kinase
Ibrolipim
T7832
Synonym: NO-1886
Target: LPL Receptor
SBC-115076
T2626
Synonym: SBC115076
Target: Others, Serine/threonin kinase
Torcetrapib
T2499
Synonym: CP-529414
Target: CETP
T0901317
T6690
Synonym:
Target: Apoptosis, FXR, Liver X Receptor, ROR
Anacetrapib
T1928
Synonym: MK-0859
Target: CETP
Probucol disuccinate
T4179
Synonym:
Target: LDL
R-IMPP
T4058
Synonym:
Target: Others, Serine/threonin kinase
Pep 2-8 ammonium salt(1541011-97-5 free base)
TP1881L1
Synonym:
Target: Others
PCSK9-IN-11
T67776
Synonym:
Target: Others
Alirocumab
T9916
Synonym:
Target: Others
Atorvastatin Sodium
T20887
Synonym: Lipitor
Target: LDL, Aquaporin, HMG-CoA Reductase
Lifibrol
T27832
Synonym: U 83860,K-12148,K-12.148,U-83860,K12148
Target: Lipid
Ro 48-8071 fumarate
T1771
Synonym:
Target: Others
CHF-4227
T68042
Synonym: Chf4227,Chf 4227
Target: Estrogen Receptor/ERR
Bococizumab
T76739
Synonym: RN316,PF-04950615
Target: Others
Carvedilol phosphate hemihydrate
T0342
Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate)
Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy
N-Acetyl lysyltyrosylcysteine amide
T38063
Synonym:
Target: Glutathione Peroxidase
Eprotirome
T5360
Synonym: KB2115
Target: Thyroid hormone receptor(THR)
Tirzepatide
TP1111
Synonym: LY-3298176
Target: Glucagon Receptor
Lysophosphatidylcholines
T36013
Synonym: ​Lyso-Lecithins (egg)
Target:
Pep2-8
TP1881
Synonym: Pep 2-8
Target:
6,8-Diprenyleriodictyol
T70504
Synonym:
Target:
Cdk2/Cyclin Inhibitory Peptide II
T76377
Synonym:
Target:
Recaticimab
T77144
Synonym:
Target:
ASM-IN-1
T74778
Synonym:
Target: Phospholipase
AR 12465
T30111
Synonym: AR-12465
Target:
PCSK9-IN-13
T73008
Synonym:
Target:
Gemcabene calcium
T11386
Synonym: PD-72953 calcium
Target: Others
Tafolecimab
T76974
Synonym:
Target:
(±)13-HODE cholesteryl ester
T35404
Synonym:
Target:
(±)9-HODE cholesteryl ester
T35405
Synonym:
Target:
Milpocitide
T74577
Synonym:
Target:
Bempedoic acid
T3625
Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002
Target: ATP Citrate Lyase, AMPK
(R)-Bambuterol
T68695
Synonym:
Target:
N-Acetyldopamine dimer-2
T75537
Synonym:
Target:
Imanixil
T15561
Synonym: HOE-402(free base)
Target: Others
PCSK9-IN-19
T79239
Synonym:
Target:
Quercetin 7-glucuronide
T80658
Synonym: Quercetin 7-O-β-glucuronide
Target: Drug Metabolite
GW590735 sodium
T69408
Synonym:
Target:
9(S)-HODE
T36727
Synonym:
Target:
Gliclazide-d4
T71981
Synonym:
Target:
Mocravimod
T28080
Synonym: KRP 203 free base,KRP-203,KRP203
Target:
AMPK activator 6
T62052
Synonym:
Target:
KDdiA-PC
T36171
Synonym:
Target:
Frovocimab
T77014
Synonym:
Target:
PCSK9 modulator-4
T60764
Synonym:
Target:
PCSK9 modulator-2
T60541
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T2S0265 Robinin NSC 9222 TLR
Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LR...
TN1438 Beta-Amyrin acetate Antioxidant , HMG-CoA Reductase , Epoxide Hydrolase , Antifungal
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
T0254 Probucol DH-581 Virus Protease , ABC , Lipid
Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.
T6S1930 Schisanhenol Schizanhenol,Gomisin-K3 Antioxidant
1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanheno...
TN1511 Cleomiscosin A LDL , Antioxidant , TNF
Cleomiscosin A is derived from Acer okamotoanum leaf and twig and shows inhibitory activity to TNF-α secretion of the mouse peritoneal macrophages. Cleomiscosin A can be used in studies about the prevention of LDL oxidat...
T2836 Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin MEK , PI3K , Endogenous Metabolite
Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin. Quercetin is an important dietary flavonoid with in vitro antioxidant activity. Isorhamnetin prevents endothelial cell injuries from oxidized LD...
TWO2727 Propane-1,2,3-triyl tripalmitate Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate Others , Endogenous Metabolite
Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. Tripalmitin increases body weight and plasma LDL levels and reduces hepatic LDL receptor mRNA levels in hamsters fed a ...
TN2967 Pinobanksin 3-acetate 3-O-Acetylpinobanksin Others , Antioxidant
Pinobanksin 3-acetate (3-O-Acetylpinobanksin), a flavonoid derivative, is a strong antioxidant found in sunflowers and honey that inhibits LDL peroxidation.
T3771 Methyl protodioscin Smilax saponin B,NSC-698790 Apoptosis
Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...
T4S2157 Campesterol (24R)-5-Ergosten-3β-ol Endogenous Metabolite
Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...
TN5171 Tricetin Apoptosis , Others , Nrf2
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...
T3427 Polydatin Piceid,Polydotin Peceid Apoptosis , Mitophagy , NF-κB , Autophagy
Polydatin (Piceid), the glycoside of Resveratrol, is originally isolated from the Chinese herb Polygonum cuspidatum. The compound can inhibit platelet aggregation and elevate the ratios of LDL-C/HDL-C and TC/HDL-C. In th...
T5S1172 Tiliroside Tribuloside Antioxidant
1. Tiliroside (Tribuloside) shows anticarcinogenic activity. 2. Tiliroside shows hepatoprotective activity. 3. Tiliroside shows antioxidant and anti-inflammatory activity, can inhibit neuroinflammation in neurodegenerati...
T2938 (E/Z)-Polydatin Polydatin,(E/Z)-Piceid Phospholipase
(E/Z)-Polydatin (Polydatin), is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, Polydatin may be det...
T5214 Cholesteryl linoleate CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester Others , Endogenous Metabolite
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via...
TN1338 7Beta-Hydroxycholesterol LDL , Calcium Channel , MAPK
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells.
TN4956 Scandoside NF-κB , MAPK
Scandoside exerts anti-inflammatory effect via suppressing NF-κB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages.It also inhibits LDL-oxidation.
TN5057 Stachybotramide LDL
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) a...
TN3675 Cleomiscosin C LDL
Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM, respectively), suggests that it could be beneficial in pr...
T36560 (±)9-HpODE
(±)9-HpODE is a racemic mixture of the fatty acid hydroperoxide product (9(S)-HpODE) formed from lipoxygenase action on linoleic acid. It shows antimicrobial activity against various fungal and bacterial pathogens and th...
T83915 Norbixin hydrate
Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ...
T36749 Herboxidiene
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin...

Natural Products

Robinin
T2S0265
Synonym: NSC 9222
Target: TLR
beta-Amyrin acetate
TN1438
Synonym:
Target: Antioxidant, HMG-CoA Reductase, Epoxide Hydrolase, Antifungal
Probucol
T0254
Synonym: DH-581
Target: Virus Protease, ABC, Lipid
Schisanhenol
T6S1930
Synonym: Schizanhenol,Gomisin-K3
Target: Antioxidant
Cleomiscosin A
TN1511
Synonym:
Target: LDL, Antioxidant, TNF
Isorhamnetin
T2836
Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,3'-Methoxyquercetin
Target: MEK, PI3K, Endogenous Metabolite
Propane-1,2,3-triyl tripalmitate
TWO2727
Synonym: Palmitic Triglyceride,Tripalmitin,Tripalmitoylglycerol,Glycerol Tripalmitate
Target: Others, Endogenous Metabolite
Pinobanksin 3-acetate
TN2967
Synonym: 3-O-Acetylpinobanksin
Target: Others, Antioxidant
Methyl protodioscin
T3771
Synonym: Smilax saponin B,NSC-698790
Target: Apoptosis
Campesterol
T4S2157
Synonym: (24R)-5-Ergosten-3β-ol
Target: Endogenous Metabolite
Tricetin
TN5171
Synonym:
Target: Apoptosis, Others, Nrf2
Polydatin
T3427
Synonym: Piceid,Polydotin Peceid
Target: Apoptosis, Mitophagy, NF-κB, Autophagy
Tiliroside
T5S1172
Synonym: Tribuloside
Target: Antioxidant
(E/Z)-Polydatin
T2938
Synonym: Polydatin,(E/Z)-Piceid
Target: Phospholipase
Cholesteryl linoleate
T5214
Synonym: CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester
Target: Others, Endogenous Metabolite
7Beta-Hydroxycholesterol
TN1338
Synonym:
Target: LDL, Calcium Channel, MAPK
Scandoside
TN4956
Synonym:
Target: NF-κB, MAPK
Stachybotramide
TN5057
Synonym:
Target: LDL
Cleomiscosin C
TN3675
Synonym:
Target: LDL
(±)9-HpODE
T36560
Synonym:
Target:
Norbixin hydrate
T83915
Synonym:
Target:
Herboxidiene
T36749
Synonym:
Target:

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00989 LDLR Protein, Human, Recombinant (His) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPK-01297 LDLR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embe...
TMPK-00402 LDLR Protein, Human, Recombinant (His & Avi) Human HEK293
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embe...
TMPY-05809 LDLR Protein, Human, Recombinant (193D/A, His) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-05499 LDLR Protein, Human, Recombinant (His), Biotinylated Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-05323 LDLR Protein, Human, Recombinant (mFc) Human HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPJ-00394 LDLR Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Low-density lipoprotein receptor 9 (LDL receptor) is a single-pass type I membrane protein which belongs to the LDLR family. It contains 3 EGF-like domains, 7 LDL-receptor class A domains, and 6 LDL-receptor class B repe...
TMPY-06834 LRP-6 Protein, Human, Recombinant (hFc) Human HEK293
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo...
TMPY-06698 LRP-6 Protein, Human, Recombinant (His) Human HEK293
Lipoprotein receptor-related protein 6 (LRP6) binds to Wnt ligands to transduce signal by stabilization of beta-catenin, which has been involved in the regulation of embryonic development and metabolism. Low density lipo...
TMPY-01881 Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His) Human HEK293
Platelet-activating factor acetylhydrolase, also known as 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycero-phosphocholine esterase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, PAF...
TMPJ-00553 Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His) Human Human Cells
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive...
TMPK-01168 LOX-1 Protein, Mouse, Recombinant (His) Mouse HEK293
LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
TMPY-06639 LRP-5 Protein, Human, Recombinant (His) Human HEK293
TMPJ-01319 TINAGL1 Protein, Human, Recombinant (His) Human Human Cells
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so ...
TMPY-01085 VLDLR Protein, Human, Recombinant (His) Human HEK293
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A...
TMPY-01014 LDLR Protein, Mouse, Recombinant (His) Mouse HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-05348 LDLR Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
LDL Receptor, also known as LDLR, is a mosaic protein that belongs to the Low-density lipoprotein receptor gene family. The low-density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved i...
TMPY-00383 LDLRAD3 Protein, Human, Recombinant (hFc) Human HEK293
TMPK-00928 VLDLR Protein, Mouse, Recombinant (His) Mouse HEK293
VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, stra...
TMPY-04310 Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His) Human HEK293
Apolipoprotein is genetically associated with the risk of Alzheimer's disease (AD). The APOA1, APOC3, and APOA4 genes are closely linked and located on human chromosome 11. There was a decreased trend for levels of APOA1...
TMPY-01081 SR-BI/SCARB1 Protein, Human, Recombinant (His) Human HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-01062 EGF Protein, Human, Recombinant (hFc) Human HEK293
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-06984 EGF Protein, Mouse, Recombinant (Yeast) Mouse Yeast
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-01560 EGF Protein, Human, Recombinant Human E. coli
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-05337 CXCL16 Protein, Human, Recombinant (His) Human HEK293
C-X-C motif chemokine 16, also known as Small-inducible cytokine B16, SR-PSOX, and CXCL16, is a single-pass type I membrane protein which belongs to the intercrine alpha (chemokine CxC) family. CXCL16 exists in transmemb...
TMPH-02253 TPM2 Protein, Human, Recombinant (His) Human E. coli
Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.
TMPH-02264 TNFSF11 Protein, Human, Recombinant (His) Human HEK293
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the tria...
TMPJ-00805 Apolipoprotein E/APOE Protein, Mouse, Recombinant (His) Mouse Human Cells
Apolipoprotein E (Apo-E), is a member of the apolipoprotein A1/A4/E family. ApoE is a major protein component of serum LDL, VLDL, HDL, and chylomicrons. APOE may function in mediating the binding, internalization, and ca...
TMPJ-01447 Apolipoprotein B-100/APOB Protein, Human, Recombinant (His) Human E. coli
Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles ...
TMPY-03371 LOX-1 Protein, Rat, Recombinant (hFc) Rat HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-04066 LOX-1 Protein, Rat, Recombinant (His) Rat HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPY-02490 LOX-1 Protein, Human, Recombinant (His) Human HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPJ-00014 Resistin Protein, Human, Recombinant (His) Human E. coli
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPY-03351 LOX-1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1 or OLR1), also known as lectin-type oxidized LDL receptor 1 (LOX1), is a receptor protein that belongs to the C-type lectin superfamily. LOX1 is a multi-liga...
TMPH-01452 Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc) HHV-6A E. coli
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells.
TMPK-01063 LRP-10 Protein, Mouse, Recombinant (His) Mouse HEK293
LDL receptor-related protein (LRP) 10 was recently identified as a Parkinson's disease gene through genome-wide linkage and sequencing analysis, but its role in Parkinson's disease in various populations is still unclear...
TMPY-00927 CD204/MSR1 Protein, Human, Recombinant (His) Human HEK293
Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contain...
TMPY-03950 CD204/MSR1 Protein, Rat, Recombinant (His) Rat HEK293
Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contain...
TMPY-02128 Serpin B1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt...
TMPK-00483 PCSK9 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injec...
TMPY-03168 CD204/MSR1 Protein, Rat, Recombinant (hFc) Rat HEK293
Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contain...
TMPY-00528 CD204/MSR1 Protein, Mouse, Recombinant (His) Mouse HEK293
Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contain...
TMPJ-00756 Apolipoprotein E/APOE3 Protein, Human, Recombinant (His) Human Human Cells
ApoE, a glycoprotein, is a structural component of very low density lipoprotein (vLDL) synthesized by the liver and intestinally synthesized chylomicrons . ApoE is also a constituent of a subclass of high density of lipo...
TMPJ-01412 LRP-12 Protein, Human, Recombinant (His) Human Human Cells
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 c...
TMPJ-01345 TCblR Protein, Human, Recombinant (His) Human Human Cells
CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recentl...
TMPJ-01344 TCblR Protein, Human, Recombinant (hFc) Human Human Cells
CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recentl...
TMPY-04692 Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His) Mouse HEK293
Platelet-activating factor acetylhydrolase, also known as 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycero-phosphocholine esterase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, PAF...
TMPY-01097 SR-BI/SCARB1 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-03012 Complement C7 Protein, Human, Recombinant (hFc) Human HEK293
Complement component 7 is a component of the complement system. It belongs to the complement C6/C7/C8/C9 family. It contains 1 EGF-like domain, 1 LDL-receptor class A domain, 1 MACPF domain, 2 Sushi (CCP/SCR) domains and...
TMPY-00131 Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG) Human HEK293
Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pi...
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LDLR Protein, Human, Recombinant (His)
TMPY-00989
Species: Human
Expression System: HEK293
LDLR Protein, Cynomolgus, Recombinant (His)
TMPK-01297
Species: Cynomolgus
Expression System: HEK293
LDLR Protein, Human, Recombinant (His & Avi)
TMPK-00402
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (193D/A, His)
TMPY-05809
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (His), Biotinylated
TMPY-05499
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (mFc)
TMPY-05323
Species: Human
Expression System: HEK293
LDLR Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00394
Species: Human
Expression System: Human Cells
LRP-6 Protein, Human, Recombinant (hFc)
TMPY-06834
Species: Human
Expression System: HEK293
LRP-6 Protein, Human, Recombinant (His)
TMPY-06698
Species: Human
Expression System: HEK293
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (His)
TMPY-01881
Species: Human
Expression System: HEK293
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
TMPJ-00553
Species: Human
Expression System: Human Cells
LOX-1 Protein, Mouse, Recombinant (His)
TMPK-01168
Species: Mouse
Expression System: HEK293
LRP-5 Protein, Human, Recombinant (His)
TMPY-06639
Species: Human
Expression System: HEK293
TINAGL1 Protein, Human, Recombinant (His)
TMPJ-01319
Species: Human
Expression System: Human Cells
VLDLR Protein, Human, Recombinant (His)
TMPY-01085
Species: Human
Expression System: HEK293
LDLR Protein, Mouse, Recombinant (His)
TMPY-01014
Species: Mouse
Expression System: HEK293
LDLR Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05348
Species: Mouse
Expression System: HEK293
LDLRAD3 Protein, Human, Recombinant (hFc)
TMPY-00383
Species: Human
Expression System: HEK293
VLDLR Protein, Mouse, Recombinant (His)
TMPK-00928
Species: Mouse
Expression System: HEK293
Apolipoprotein A-IV/APOA4 Protein, Human, Recombinant (His)
TMPY-04310
Species: Human
Expression System: HEK293
SR-BI/SCARB1 Protein, Human, Recombinant (His)
TMPY-01081
Species: Human
Expression System: HEK293
EGF Protein, Human, Recombinant (hFc)
TMPY-01062
Species: Human
Expression System: HEK293
EGF Protein, Mouse, Recombinant (Yeast)
TMPY-06984
Species: Mouse
Expression System: Yeast
EGF Protein, Human, Recombinant
TMPY-01560
Species: Human
Expression System: E. coli
CXCL16 Protein, Human, Recombinant (His)
TMPY-05337
Species: Human
Expression System: HEK293
TPM2 Protein, Human, Recombinant (His)
TMPH-02253
Species: Human
Expression System: E. coli
TNFSF11 Protein, Human, Recombinant (His)
TMPH-02264
Species: Human
Expression System: HEK293
Apolipoprotein E/APOE Protein, Mouse, Recombinant (His)
TMPJ-00805
Species: Mouse
Expression System: Human Cells
Apolipoprotein B-100/APOB Protein, Human, Recombinant (His)
TMPJ-01447
Species: Human
Expression System: E. coli
LOX-1 Protein, Rat, Recombinant (hFc)
TMPY-03371
Species: Rat
Expression System: HEK293
LOX-1 Protein, Rat, Recombinant (His)
TMPY-04066
Species: Rat
Expression System: HEK293
LOX-1 Protein, Human, Recombinant (His)
TMPY-02490
Species: Human
Expression System: HEK293
Resistin Protein, Human, Recombinant (His)
TMPJ-00014
Species: Human
Expression System: E. coli
LOX-1 Protein, Cynomolgus, Recombinant (His)
TMPY-03351
Species: Cynomolgus
Expression System: HEK293
Human herpesvirus 6A (HHV-6 variant A) (strain GS) Glycoprotein 105 (His & Myc)
TMPH-01452
Species: HHV-6A
Expression System: E. coli
LRP-10 Protein, Mouse, Recombinant (His)
TMPK-01063
Species: Mouse
Expression System: HEK293
CD204/MSR1 Protein, Human, Recombinant (His)
TMPY-00927
Species: Human
Expression System: HEK293
CD204/MSR1 Protein, Rat, Recombinant (His)
TMPY-03950
Species: Rat
Expression System: HEK293
Serpin B1 Protein, Human, Recombinant (His)
TMPY-02128
Species: Human
Expression System: Baculovirus-Insect Cells
PCSK9 Protein, Cynomolgus, Recombinant (His)
TMPK-00483
Species: Cynomolgus
Expression System: HEK293
CD204/MSR1 Protein, Rat, Recombinant (hFc)
TMPY-03168
Species: Rat
Expression System: HEK293
CD204/MSR1 Protein, Mouse, Recombinant (His)
TMPY-00528
Species: Mouse
Expression System: HEK293
Apolipoprotein E/APOE3 Protein, Human, Recombinant (His)
TMPJ-00756
Species: Human
Expression System: Human Cells
LRP-12 Protein, Human, Recombinant (His)
TMPJ-01412
Species: Human
Expression System: Human Cells
TCblR Protein, Human, Recombinant (His)
TMPJ-01345
Species: Human
Expression System: Human Cells
TCblR Protein, Human, Recombinant (hFc)
TMPJ-01344
Species: Human
Expression System: Human Cells
Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His)
TMPY-04692
Species: Mouse
Expression System: HEK293
SR-BI/SCARB1 Protein, Mouse, Recombinant (His & hFc)
TMPY-01097
Species: Mouse
Expression System: HEK293
Complement C7 Protein, Human, Recombinant (hFc)
TMPY-03012
Species: Human
Expression System: HEK293
Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG)
TMPY-00131
Species: Human
Expression System: HEK293
TargetMol