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Search Result

Search Results for " kinesin "

Targets

Kinesin Kinesin

40

Compounds

5

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T3118 Dimethylenastron Kinesin
Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.
T4048 Monastrol (±)-Monastrol Apoptosis , Kinesin
Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T2039 GSK-923295 Apoptosis , Kinesin
GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).
T6209 CW-069 CW069 Kinesin , Microtubule Associated
CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.
T36816 S-trityl-L-Cysteine STLC Kinesin
S-trityl-L-Cysteine is a non-natural amino acid and an inhibitor of Eg5, also known as KSP and Kif11, a mitotic kinesin necessary for mitotic spindle formation. S-trityl-L-Cysteine inhibits the ATPase activity of Eg5 in ...
T12359 Paprotrain (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile Kinesin
Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
T6393 ARQ 621 Kinesin
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
T3120 K858 (Racemic) K858 Racemic,K858 Apoptosis , Kinesin
K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.
T2255 SB-743921 hydrochloride SB743921 HCl,SB743921 Kinesin , KSP
SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).
T2103 Ispinesib CK0238273,SB-715992 Apoptosis , Kinesin , KSP
Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic properties.
T8342 BRD9876 Others , Kinesin , Microtubule Associated
BRD9876 is a selective inhibitor of MM1S growth.
T9207 GW406108X GW108X Kinesin , Autophagy
GW406108X (GW108X) is a Kif15 inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X is also an ULK1 kinase inhibitor with pIC50 values of 6.37 (427 nM) and block autophagic flux.
T39994 Sovilnesib Microtubule Associated
Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.
T9207L GW406108X(Z/E) Kinesin , Autophagy
GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .
T23543 YIL 781 GHSR
YIL 781 is a selective ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM), showing a weak affinity for kinesin receptors (K = 6 μM). YIL 781 improves glucose homeostasis in vivo and in vitro by blocking ghrelin secretion...
TQ0318 Filanesib ARRY-520,ARRY 520 KSP
Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.
T60026 KIF18A-IN-2 Microtubule Associated
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
TQ0318L ARRY 520 hydrochloride KSP
ARRY 520 hydrochloride is a kinesin spindle protein (KSP) inhibitor.ARRY 520 hydrochloride induces cell death by apoptosis and has potent anti-proliferative activity.
T77586 Eg5-IN-1 Kinesin
Eg5-IN-1 is a potent inhibitor of the kinesin family of motor proteins (Eg5) with an IC50 value of 1.97 µM for Eg5.Eg5-IN-1 can be used in cancer research.
T9682 AZD-4877 AZD4877 Apoptosis , Kinesin
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and med...
TQ0314 EMD534085 Kinesin
EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).
T25409 FCPT
FCPT is an ATP competitive kinesin-5 inhibitor.
T24490 MMV666693 MMV-666693,MMV 666693
MMV666693 is a selective allosteric Plasmodium Kinesin-5 inhibitor.
T30308 BDPSB
BDPSB is a highly efficient photocontroller of mitotic kinesin Eg5 ATPase activity.
T24150 HR22C16 HR-22-C-16,HR 22 C 16
HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.
T30573 BQS-481
BQS-481 inhibits Kinesin-like protein KIF11.
T11759 Kif15-IN-2 Others
Kif15-IN-2 is used for the research of cellular proliferative diseases. Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15.
T63726 AM-5308
AM-5308 is a potent inhibitor of the kinesin KIF18A.
T21321 MK-0731
MK-0731, a synthetic small molecule with potential antineoplastic activity, selectively inhibits kinesin spindle protein (KSP), leading to the inhibition of mitotic spindle assembly, induction of cell cycle arrest during...
T4649 (S)-Monastrol Kinesin
Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T11859 Litronesib Racemate LY-2523355 Racemate,KF-89617 Racemate Others
Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.
T68743 AZD4877 HCl
AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may re...
T11859L Litronesib KF-89617,LY-2523355 Kinesin
Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T15661 Kif15-IN-1 Others
Kif15-IN-1, a mitotic Kinesin family member 15 (Kif15) inhibitor, is utilized in the study of cellular proliferative diseases.
T28694 SB-743921 free base SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921
SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).
T10428 AZ82 Microtubule Associated
AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor (Ki: 43 nM; IC50: 300 nM for KIFC1).
T25418 Filanesib TFA Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA
Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, in...
T10373 (R)-Filanesib (R)-ARRY-520 Others
(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).
T40232 KIF18A-IN-1 KIF18A-IN-1
KIF18A-IN-1 is a potent inhibitor of the mitotic kinesin KIF18A. This compound demonstrates significant anti-tumor properties.
T78125 PVZB1194 Kinesin
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 alloster...

Compounds

Dimethylenastron
T3118
Synonym:
Target: Kinesin
Monastrol
T4048
Synonym: (±)-Monastrol
Target: Apoptosis, Kinesin
GSK-923295
T2039
Synonym:
Target: Apoptosis, Kinesin
CW-069
T6209
Synonym: CW069
Target: Kinesin, Microtubule Associated
S-trityl-L-Cysteine
T36816
Synonym: STLC
Target: Kinesin
Paprotrain
T12359
Synonym: (alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile
Target: Kinesin
ARQ 621
T6393
Synonym:
Target: Kinesin
K858 (Racemic)
T3120
Synonym: K858 Racemic,K858
Target: Apoptosis, Kinesin
SB-743921 hydrochloride
T2255
Synonym: SB743921 HCl,SB743921
Target: Kinesin, KSP
Ispinesib
T2103
Synonym: CK0238273,SB-715992
Target: Apoptosis, Kinesin, KSP
BRD9876
T8342
Synonym:
Target: Others, Kinesin, Microtubule Associated
GW406108X
T9207
Synonym: GW108X
Target: Kinesin, Autophagy
Sovilnesib
T39994
Synonym:
Target: Microtubule Associated
GW406108X(Z/E)
T9207L
Synonym:
Target: Kinesin, Autophagy
YIL 781
T23543
Synonym:
Target: GHSR
Filanesib
TQ0318
Synonym: ARRY-520,ARRY 520
Target: KSP
KIF18A-IN-2
T60026
Synonym:
Target: Microtubule Associated
ARRY 520 hydrochloride
TQ0318L
Synonym:
Target: KSP
Eg5-IN-1
T77586
Synonym:
Target: Kinesin
AZD-4877
T9682
Synonym: AZD4877
Target: Apoptosis, Kinesin
EMD534085
TQ0314
Synonym:
Target: Kinesin
FCPT
T25409
Synonym:
Target:
MMV666693
T24490
Synonym: MMV-666693,MMV 666693
Target:
BDPSB
T30308
Synonym:
Target:
HR22C16
T24150
Synonym: HR-22-C-16,HR 22 C 16
Target:
BQS-481
T30573
Synonym:
Target:
Kif15-IN-2
T11759
Synonym:
Target: Others
AM-5308
T63726
Synonym:
Target:
MK-0731
T21321
Synonym:
Target:
(S)-Monastrol
T4649
Synonym:
Target: Kinesin
Litronesib Racemate
T11859
Synonym: LY-2523355 Racemate,KF-89617 Racemate
Target: Others
AZD4877 HCl
T68743
Synonym:
Target:
Litronesib
T11859L
Synonym: KF-89617,LY-2523355
Target: Kinesin
Kif15-IN-1
T15661
Synonym:
Target: Others
SB-743921 free base
T28694
Synonym: SB743921,SB-921,SB921,SB-743921,GSK-743921,GSK-921
Target:
AZ82
T10428
Synonym:
Target: Microtubule Associated
Filanesib TFA
T25418
Synonym: Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA
Target:
(R)-Filanesib
T10373
Synonym: (R)-ARRY-520
Target: Others
KIF18A-IN-1
T40232
Synonym: KIF18A-IN-1
Target:
PVZB1194
T78125
Synonym:
Target: Kinesin

Recombinant Proteins

Species：
Human (4)
Mouse (1)
Expression System：
Baculovirus-Insect Cells (3)
E. coli (2)
Tag：
His,GST (2)
N-6His (1)
N-terminal GST-tagged (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPY-00522 KLC2 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
TMPY-03993 KIAA1279 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The ...
TMPY-00589 KIAA1279 Protein, Human, Recombinant Human Baculovirus-Insect Cells
KIFBP (Kinesin Family Binding Protein, also known as KIAA1279 and KIF1BP) is a Protein Coding gene. This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratricopeptide repeats. The ...
TMPJ-00972 CDKN1B Protein, Human, Recombinant (His) Human E. coli
Cyclin-Dependent Kinase Inhibitor 1B (CDKN1B) is a Kinesin-related motor protein necessary for mitotic spindle assembly and chromosome segregation. CDKN1B is expressed in all tissues with highest levels observed in skele...
TMPH-02846 BICD2 Protein, Mouse, Recombinant (GST) Mouse E. coli
Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction...
Cat No. Product Name
L1310 Cytoskeletal Signaling Pathway Compound Library

773 compounds
A unique collection of 773 cytoskeleton-related compounds, can be used for HTS and HCS；

Libraries

Cytoskeletal Signaling Pathway Compound Library
L1310
Compounds: 773
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