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Search Results for " ikk "

Targets

61

Compounds

12

Natural Products

24

Recombinant Proteins

3

Libraries

Cat No. Product Name Synonyms Targets
T6176 IKK 16 IKK Inhibitor VII,IKK-16,IKK16 IκB/IKK , LRRK2
IKK 16 (IKK Inhibitor VII) is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
T40700 IKK-IN-3
IKK-IN-3 is a highly potent and selective inhibitor of IkappaB kinase 2 (IKK2 or IKKβ). It exhibits impressive inhibitory activity against IKK2 (IC50 = 19 nM), while also demonstrating significant efficacy against IKK1 (...
T15557 IKK 16 hydrochloride Others
IKK 16 hydrochloride is a selective IKK2, IKK complex, and IKK1 IκB kinase (IKK) inhibitor (IC50s: 40 nM, 70 nM and 200 nM, respectively). IKK16 inhibits leucine-rich repeat kinase-2 (LRRK2; IC50: 50 nM).
T3094 PS-1145 IKK Inhibitor X Apoptosis , IκB/IKK
PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.
T10237 ACHP Hydrochloride IKK-2 Inhibitor VIII IκB/IKK
ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.
T11633 IKK-IN-1 IκB/IKK
IKK-IN-1 is an inhibitor of IKK.
T22021 ACHP IKK-2 Inhibitor VIII IκB/IKK
ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-α and IKK-β. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression thro...
T6326 BMS-345541 BMS-345541 free base,IKK Inhibitor III,BMS345541 IκB/IKK
BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.
T61059 IKK-IN-4
IKK-IN-4 is a potent and selective inhibitor of IkappaB kinase 2 with IC 50 values of 45 and 650 nM against IKKβ and IKKα, respectively [1].
TQ0306 MLN120B IκB/IKK
MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).
T2279 Tizoxanide Desacetyl-nitazoxanide,TIZ Antiviral , HIV Protease , Antibacterial , Autophagy
Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine. Lamivudine (2', 3'-dideoxy-3'-thiacytidine, commonly called 3TC) is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
T6771 AZD3264 IκB/IKK
AZD3264 is a new type IKK2 inhibitor.
T5540 GSK8612 IκB/IKK
GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .
T7951 TBK1/IKKε-IN-5 IκB/IKK
TBK1/IKKε-IN-5 is a dual TBK1 and IKKε inhibitor(IC50 of 1 nM and 5.6 nM, respectively).
T15564 IMD-0560 IκB/IKK
IMD-0560 is a novel inhibitor of IκB kinase β.
T5209 INH14 IκB/IKK
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).
T1830 BX795 IκB/IKK , Chk , CDK , c-Kit , PDK , Autophagy
BX795 is an effective and selective PDK1 inhibitor (IC50: 6 nM), and its selectivity is 140- and 1600-fold for PDK1 over PKA and PKC in cell-free assays, respectively. Meanwhile, the selectivity for PDK1 is 100-fold than...
T15559 TBK1/IKKε-IN-2 IκB/IKK
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.
T8705 BOT-64 IκB/IKK
BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole compound
T10477 BAY-985 IκB/IKK
BAY-985 is a potent, selective, and orally active ATP-competitive dual inhibitor of TBK1 and IKKε (IC50s: 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε) with antitumor efficacy.
T2081 LY2409881 trihydrochloride LY2409881 Apoptosis , IκB/IKK
LY2409881 trihydrochloride is a novel specific inhibitor of IKK2 (IC50: 30 nM); IC50 for IKK1 and other common kinases is at least one log higher.
T6141 IMD-0354 IKK2 Inhibitor V,IMD 0354 IκB/IKK
IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.
T2118 SC-514 GK 01140 IκB/IKK , p38 MAPK , Serine Protease , CDK , Aurora Kinase
SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
TD0099 Malachite green oxalate Apoptosis , Others , IκB/IKK , NF-κB
Malachite green oxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions.
T36524 IKK2-IN-4 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide,IKK2 Inhibitor IV IκB/IKK , TNF
IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.
T3049 TPCA-1 GW683965,IKK2 Inhibitor IV,TPCA1 Apoptosis , IκB/IKK , STAT
TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.
T1902 BAY 11-7082 BAY 11-7821 Apoptosis , Others , IκB/IKK , DUB , Autophagy
BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM). BAY 11-7082 is also an inhibitor of the ubiquitin-specific proteases USP7 and USP21 (IC50=0.19/0.96 μM).
T0097 MRT67307 MRT67307 HCl IκB/IKK , Autophagy
Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...
T8542 BMS-345541 hydrochloride IκB/IKK
BMS-345541 hydrochloride is a selective IKK inhibitor (IKK2 and IKK1 with IC50 of 0.3 μM and 4 μM,respectively).
T1639 Amlexanox CHX3673,Amoxanox,AA673 IL Receptor , FGFR , Others , IκB/IKK
Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexan...
T0708 Oxaprozin Oxaprozinum,Wy21743 NF-κB , COX
Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...
T25465 GS143 GS-143,GS 143 IκB/IKK , E1/E2/E3 Enzyme , NF-κB
GS143 is a selec­tive IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB acti­va­tion and tran­scrip­tion of tar­get genes and does not inhibit protea...
T9105 NF-κB-IN-1 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)- IκB/IKK , NF-κB
NF-κB-IN-1 (1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-) is a potent NF-κB signaling pathway inhibitor. It is a 4-arylidene crucumin analogue. NF-κB-IN-1 dir...
TP1615L IKKγ NBD Inhibitory Peptide acetate IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base) NF-κB
IKKγ NBD Inhibitory Peptide acetate is a NEMO-binding domain peptide (NBD peptide) acetate corresponding to the NEMO amino-terminal alpha-helical region. IKKγ NBD Inhibitory Peptide acetate is shown to block TNF-alpha-in...
TP1615 IKKγ NBD Inhibitory Peptide
A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO ...
T63919 IKKβ-IN-1
IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) (IC50: 0.20 μM). IKKβ-IN-1 reduces the inhibition of PGE2 and TNF-α production in murine macrophages. IKKβ-IN-1 protects mice from infection shock-induced...
T33672 Nikkomycin pseudo-J
Nikkomycin pseudo-J is a nikkomycin isolated from Streptomyces tendae.
T13097 TBK1/IKKε-IN-1 IκB/IKK
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
T25870 Nikkomycin Nikkomycin I
Nikkomycin is used as an insecticide.
T79690 FIKK9.1-IN-1 Parasite
FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1, thereby disrupting the parasite life cycle and resulting in ...
T71747 IKKß-IN-124
IKKß-IN-124 is an allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation.
T25872 Nikkomycin M
Nikkomycin M is used as an insecticide.
T25871 Nikkomycin J
Nikkomycin J is used as an insecticide from Streptomyces tendae.
T33671 Nikkomycin N
Nikkomycin N is a bioactive chemical.
T39841 TBK1/IKKε-IN-6 TBK1/IKKε-IN-6
TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.
T8814 Nikkomycin Z Nikkomycin Z from Streptomyces tendae Others , Antibiotic , Antifungal
Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects, acarids and yeasts.
T38263 TBK1/IKKε-IN-4 TBK1/IKKε-IN-4
TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ...
T76024 IKKγ NBD Inhibitory Peptide TFA
IKKγ NBD Inhibitory Peptide TFA is a specific NF-κB inhibitor that functions by hindering the interaction between the IKKγ/NEMO-binding domain (NBD) and IKKα and IKKβ. This action effectively prevents TNF-α-induced NF-kB...
T26957 CAY10575 CAY-10575,CAY 10575
CAY10575, a benzimidazole analog IKK-ε inhibitor, inhibits IKK-ε with an IC50 value of ~15.8 µM.
T11573 HPN-01 Others
HPN-01 is a selective IKK inhibitor (pIC50s: 6.4, 7.0, and <4.8 for IKK-α, IKK-β, and IKK-ε). HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, ErbB2, EGFR, GS...

Compounds

IKK 16
T6176
Synonym: IKK Inhibitor VII,IKK-16,IKK16
Target: IκB/IKK, LRRK2
IKK-IN-3
T40700
Synonym:
Target:
IKK 16 hydrochloride
T15557
Synonym:
Target: Others
PS-1145
T3094
Synonym: IKK Inhibitor X
Target: Apoptosis, IκB/IKK
ACHP Hydrochloride
T10237
Synonym: IKK-2 Inhibitor VIII
Target: IκB/IKK
IKK-IN-1
T11633
Synonym:
Target: IκB/IKK
ACHP
T22021
Synonym: IKK-2 Inhibitor VIII
Target: IκB/IKK
BMS-345541
T6326
Synonym: BMS-345541 free base,IKK Inhibitor III,BMS345541
Target: IκB/IKK
IKK-IN-4
T61059
Synonym:
Target:
MLN120B
TQ0306
Synonym:
Target: IκB/IKK
Tizoxanide
T2279
Synonym: Desacetyl-nitazoxanide,TIZ
Target: Antiviral, HIV Protease, Antibacterial, Autophagy
AZD3264
T6771
Synonym:
Target: IκB/IKK
GSK8612
T5540
Synonym:
Target: IκB/IKK
TBK1/IKKε-IN-5
T7951
Synonym:
Target: IκB/IKK
IMD-0560
T15564
Synonym:
Target: IκB/IKK
INH14
T5209
Synonym:
Target: IκB/IKK
BX795
T1830
Synonym:
Target: IκB/IKK, Chk, CDK, c-Kit, PDK, Autophagy
TBK1/IKKε-IN-2
T15559
Synonym:
Target: IκB/IKK
BOT-64
T8705
Synonym:
Target: IκB/IKK
BAY-985
T10477
Synonym:
Target: IκB/IKK
LY2409881 trihydrochloride
T2081
Synonym: LY2409881
Target: Apoptosis, IκB/IKK
IMD-0354
T6141
Synonym: IKK2 Inhibitor V,IMD 0354
Target: IκB/IKK
SC-514
T2118
Synonym: GK 01140
Target: IκB/IKK, p38 MAPK, Serine Protease, CDK, Aurora Kinase
Malachite green oxalate
TD0099
Synonym:
Target: Apoptosis, Others, IκB/IKK, NF-κB
IKK2-IN-4
T36524
Synonym: 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide,IKK2 Inhibitor IV
Target: IκB/IKK, TNF
TPCA-1
T3049
Synonym: GW683965,IKK2 Inhibitor IV,TPCA1
Target: Apoptosis, IκB/IKK, STAT
BAY 11-7082
T1902
Synonym: BAY 11-7821
Target: Apoptosis, Others, IκB/IKK, DUB, Autophagy
MRT67307
T0097
Synonym: MRT67307 HCl
Target: IκB/IKK, Autophagy
BMS-345541 hydrochloride
T8542
Synonym:
Target: IκB/IKK
Amlexanox
T1639
Synonym: CHX3673,Amoxanox,AA673
Target: IL Receptor, FGFR, Others, IκB/IKK
Oxaprozin
T0708
Synonym: Oxaprozinum,Wy21743
Target: NF-κB, COX
GS143
T25465
Synonym: GS-143,GS 143
Target: IκB/IKK, E1/E2/E3 Enzyme, NF-κB
NF-κB-IN-1
T9105
Synonym: 1,6-Heptadiene-3,5-dione, 1,7-bis(3,4-dimethoxyphenyl)-4-[(4-hydroxy-3-methoxyphenyl)methylene]-, (1E,6E)-
Target: IκB/IKK, NF-κB
IKKγ NBD Inhibitory Peptide acetate
TP1615L
Synonym: IKKγ NBD Inhibitory Peptide acetate(372146-18-4 free base)
Target: NF-κB
IKKγ NBD Inhibitory Peptide
TP1615
Synonym:
Target:
IKKβ-IN-1
T63919
Synonym:
Target:
Nikkomycin pseudo-J
T33672
Synonym:
Target:
TBK1/IKKε-IN-1
T13097
Synonym:
Target: IκB/IKK
Nikkomycin
T25870
Synonym: Nikkomycin I
Target:
FIKK9.1-IN-1
T79690
Synonym:
Target: Parasite
IKKß-IN-124
T71747
Synonym:
Target:
Nikkomycin M
T25872
Synonym:
Target:
Nikkomycin J
T25871
Synonym:
Target:
Nikkomycin N
T33671
Synonym:
Target:
TBK1/IKKε-IN-6
T39841
Synonym: TBK1/IKKε-IN-6
Target:
Nikkomycin Z
T8814
Synonym: Nikkomycin Z from Streptomyces tendae
Target: Others, Antibiotic, Antifungal
TBK1/IKKε-IN-4
T38263
Synonym: TBK1/IKKε-IN-4
Target:
IKKγ NBD Inhibitory Peptide TFA
T76024
Synonym:
Target:
CAY10575
T26957
Synonym: CAY-10575,CAY 10575
Target:
HPN-01
T11573
Synonym:
Target: Others
1 2
Cat No. Product Name Synonyms Targets
T3384 Wedelolactone IKK Inhibitor II Apoptosis , NF-κB , Lipoxygenase , Caspase
Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.
T5796 Plantainoside D Isoplantamajoside RAAS , PKC
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ...
T0167 Vinpocetine RGH-4405,Ethyl apovincaminate IκB/IKK , NF-κB , Sodium Channel , PDE
Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).
T1558 Resveratrol trans-Resveratrol,SRT 501 Apoptosis , Mitophagy , IκB/IKK , Lipoxygenase , Sirtuin , COX , NADPH , DNA/RNA Synthesis , Nrf2 , Antibacterial , Antibiotic , Autophagy , Antifungal
Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autop...
T5S0734 Desmethoxyyangonin Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain Others , Monoamine Oxidase
1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T4S1050 Pristimerin Celastrol methyl ester NF-κB , Antibacterial
1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...
TJS1779 Protosappanin A PTA NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ...
T6S0735 Flavokawain B Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone Apoptosis , Others
1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...
TN1504 Citreorosein cAMP , NF-κB , PI3K
Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation an...
TN2327 Zedoarondiol NOS , NF-κB , COX
Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway.
T4700 1,3,5-Trihydroxy-4-prenylxanthone
1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylch...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01100 UBE2V1 Protein, Human, Recombinant (His) Human E. coli
Ubiquitin-Conjugating Enzyme Variant 1a (UBE2V1) is a member of the Ubiquitin-conjugating (E2) enzyme family. The E2 catalytic core domain of UBE2V1 lacks an active site cysteine residue, rendering it catalytically inact...
TMPY-01814 GASP-1/WFIKKN2 Protein, Human, Recombinant (His) Human HEK293
WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2, also known as Growth and differentiation factor-associated serum protein 1, WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-relat...
TMPY-03213 BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05568 BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04493 BCMA/TNFRSF17 Protein, Human, Recombinant (rFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPH-01531 IKBKB Protein, Human, Recombinant (His) Human Baculovirus
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. A...
TMPH-01532 IKBKB Protein, Human, Recombinant (E. coli, His) Human E. coli
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. A...
TMPY-02544 FANCA Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPH-02194 TAB2 Protein, Human, Recombinant (His & Myc) Human Baculovirus
Adapter required to activate the JNK and NF-kappa-B signaling pathways through the specific recognition of 'Lys-63'-linked polyubiquitin chains by its RanBP2-type zinc finger (NZF). Acts as an adapter linking MAP3K7/TAK1...
TMPY-05136 BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated Rhesus HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-00966 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05328 BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-06757 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05385 BCMA/TNFRSF17 Protein, Human, Recombinant (hFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05567 BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02913 BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc) Rat HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05197 BCMA/TNFRSF17 Protein, Human, Recombinant (mFc) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-05595 BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-01211 BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc) Mouse HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPH-01001 BCL10 Protein, Human, Recombinant (His & SUMO) Human E. coli
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing...
TMPH-01554 IFIH1 Protein, Human, Recombinant (His) Human E. coli
Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type...
TMPH-02521 PYCARD Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mit...
TMPH-02640 ZC3H12A Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angi...
UBE2V1 Protein, Human, Recombinant (His)
TMPJ-01100
Species: Human
Expression System: E. coli
GASP-1/WFIKKN2 Protein, Human, Recombinant (His)
TMPY-01814
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rhesus, Recombinant (hFc)
TMPY-03213
Species: Rhesus
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
TMPY-05568
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (rFc)
TMPY-04493
Species: Human
Expression System: HEK293
IKBKB Protein, Human, Recombinant (His)
TMPH-01531
Species: Human
Expression System: Baculovirus
IKBKB Protein, Human, Recombinant (E. coli, His)
TMPH-01532
Species: Human
Expression System: E. coli
FANCA Protein, Human, Recombinant (His)
TMPY-02544
Species: Human
Expression System: Baculovirus-Insect Cells
TAB2 Protein, Human, Recombinant (His & Myc)
TMPH-02194
Species: Human
Expression System: Baculovirus
BCMA/TNFRSF17 Protein, Rhesus, Recombinant, Biotinylated
TMPY-05136
Species: Rhesus
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc)
TMPY-00966
Species: Mouse
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi)
TMPY-05328
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06757
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (hFc)
TMPY-05385
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human (His & hFc), FITC conjugated
TMPY-05567
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Rat, Recombinant (hFc)
TMPY-02913
Species: Rat
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (mFc)
TMPY-05197
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
TMPY-05595
Species: Mouse
Expression System: HEK293
BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & hFc)
TMPY-01211
Species: Mouse
Expression System: HEK293
BCL10 Protein, Human, Recombinant (His & SUMO)
TMPH-01001
Species: Human
Expression System: E. coli
IFIH1 Protein, Human, Recombinant (His)
TMPH-01554
Species: Human
Expression System: E. coli
PYCARD Protein, Mouse, Recombinant (His & Myc)
TMPH-02521
Species: Mouse
Expression System: E. coli
ZC3H12A Protein, Mouse, Recombinant (His & Myc)
TMPH-02640
Species: Mouse
Expression System: E. coli
Cat No. Product Name
L3800 NF-κB Signaling Compound Library

740 compounds
A unique collection of 740 compounds targeting NF-κB signaling for high throughput screening and high content screening;
L1610 FDA-Approved Kinase Inhibitor Library

266 compounds
Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、...
L1600 Kinase Inhibitor Library

2720 compounds
A unique collection of 2720 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;
TargetMol