Home Tools
Log in
Cart

Search Result

Search Results for " i/r "

Targets

45

Compounds

17

Natural Products

32

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T72322 R 59-022 hydrochloride DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride 5-HT Receptor , PKC
R 59-022 hydrochloride (DKGI-I hydrochloride) is a 5-HT Receptor antagonist that activates protein kinase C (PKC).R 59-022 hydrochloride is a DGK inhibitor (IC50:2.8 µM) that inhibits the phosphorylation of OAG to OAPA.R...
T16709 R 59-022 Diacylglycerol kinase inhibitor I,DKGI-I Others
R 59-022 is a 5-HTR antagonist and activates protein kinase C (PKC). R 59-022 is a diacylglycerol kinase inhibitor (IC50=2.8 μM). R 59-022 potentiates thrombin-induced diacylglycerol production in platelets and inhibits ...
T8476 RSVA405 RSVA 405 AMPK , STAT , Autophagy
RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor
T6547 Ipratropium Bromide Sch 1000,Itrop,Atrovent AChR
Ipratropium Bromide (Sch 1000) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis and emphysema.
T19930 Nitrosoglutathione S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO RAAS , NO Synthase
Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, i...
T0098 Ipratropium bromide monohydrate Ipratropium bromide hydrate AChR
Ipratropium bromide monohydrate (Ipratropium bromide hydrate) is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for various bronchial...
TD0001 SYBR GREEN 1 SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO Others
SYBR Green I is an asymmetrical cyanine dye, which is used to detect nucleic acids. It consists of a N-alkylated benzothiazolium or benzoxazolium ring system, that is joined by a monomethine bridge to a pyridinium or qui...
T4535 Etomoxir sodium salt (R)-Etomoxir sodium salt,Na salt,Etomoxir Apoptosis , Others
(R)-Etomoxir sodium salt ((R)-Etomoxir sodium salt) is R-form of Etomoxir. Etomoxir is a potent inhibitor of carnitine palmitoyltransferase-I (CPT-1).
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T22031 ANR 94 Adenosine Receptor
ANR94 is a potent and selective adenosine A 2A receptor (AA 2A R) antagonist with an K i of 46 nM for hAA 2A R. ANR94 has the potential for Parkinson's disease research [1] [2].
T4191 Multi-kinase inhibitor 1 Multi-kinase inhibitor I Others , Bcr-Abl , PDGFR , c-Kit
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.
T30981 Clometocillin Penicilline 356
Clometocillin is a penicillin that can active penicillin to pen-I or pen-R pneumococci.
T15672 KU14R Others
KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.
T33451 ML 7 ML7,ML-7
ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury.
T61491 (R)-ND-336
(R)-ND-336 is a highly potent and selective MMP-9 inhibitor, displaying a K i value of 19 nM. It also exhibits inhibitory activity against MMP-2 (K i = 127 nM) and MMP-14 (K i =119 nM). With its significant potential, (R...
T39870 5-HT7R antagonist 1 free base 5-HT7R antagonist 1 free base
5-HT7R antagonist 1 (free base) is a G protein-biased antagonist against 5-HT 7 R ( K i = 6.5 nM).
T74331 HCAII-IN-7
hCAII-IN-7 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor with K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively [1] .
T22140 (R)-SLV 319
(R)-SLV 319 is a potent and selective antagonist of cannabinoid receptor 1 (CB1), with a K i value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319 [1]
T74723 MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan. Exatecan is a DNA Topoisomerase I inhibitor.
T61980 Carbonic anhydrase inhibitor 8
Carbonic anhydrase inhibitor 8 (compound R-13) is a potent human carbonic anhydrase (hCA). Carbonic anhydrase inhibitor 8 shows K i values of 60.7 nM, 320.7 nM, 2298 nM for hCA I, hCA II, hCA IV, respectively.
T39795 Tricarbonyldichlororuthenium(II) dimer CORM-2
Tricarbonyldichlororuthenium(II) dimer, a pharmacological CO donor, prevents ischemia/reperfusion (I/R)-induced oxidative damage to the gastric mucosa by enhancing gastric blood flow (GBF) and reducing DNA oxidation and ...
T61982 Human carbonic anhydrase II-IN-2
Human carbonic anhydrase II-IN-24 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor. Human carbonic anhydrase II-IN-24 shows K i s of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respective...
T71001 GSK-598809
GSK598809 is a selective D(3)R antagonist recently progressed in Phase I trials. GSK-598809 may decrease the rewarding effects of contextual cues associated with drug intake preclinically, which may reduce drug craving i...
T73682 (R)-Lanicemine
(R)-Lanicemine ((R)-AZD6765) is the less active R-enantiomer of Lanicemine. Lanicemine (AZD6765) is a low-trapping NMDA channel blocker ( K i of 0.56-2.1 μM for NMDA receptor ; IC 50 s of 4-7 μM and 6.4 μM in CHO and Xen...
T83043 Anti-MI/R injury agent 1
Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R) injury. It improves cell viability in cardiomyocytes subjec...
T37680 3-hydroxy Palmitic Acid methyl ester
3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increase...
T81267 RIPK3-IN-4 RIP kinase
RIPK3-IN-4 (Compound 42) is a RIPK3 inhibitor that mitigates necroptosis, inflammatory responses, and HK-2 cell damage. It alleviates acute kidney injury by attenuating Cisplatin- and I/R-induced kidney damage, along wit...
T74724 MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC, consisting Exatecan. Exatecan is a DNA Topoisomerase I inhibitor.
T74350 Neuropeptide Y Y1 receptor antagonist 1
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y 1 receptor (Y 1 R) , with a K i of 0.19 nM [1] . Storage: protect from light .
T76223 NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)
Compound 39 (NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)) is a potent agonist of the APJ receptor, possessing a K i value of 0.6 nM. It is capable of activating Gαi1, with an EC 50 of 0.8 nM, and of recruiting β-arrestin2, with an E...
T80138 (D-Arg8)-Inotocin Vasopressin Receptor
'(D-Arg8)-Inotocin is a potent, selective, and competitive antagonist of the vasopressin receptor (V 1a R), exhibiting a binding affinity (K i) of 1.3 nM. It demonstrates over 3000-fold selectivity for the human V1aR com...
T38329 CU-76
CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sens...
T37887 1-Heptadecanoyl-rac-glycerol
1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 μg/ml for all)....
T38328 CU-32
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS ...
T72091 ADRA1D receptor antagonist 1 free base
ADRA1D receptor antagonist 1 (free base) antagonist ( K i =1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC 30 value of 15 nM. ADRA1D receptor antagonist 1 (free...
T72213 Efonidipine hydrochloride NZ-105 hydrochloride
Efonidipine Hcl (NZ-105) is a dual T-type and L-type calcium channel blocker (CCB). IC50 value: Target: calcium channel blocker in vitro: Efonidipine and nifedipine, but not other examined CCB...
T35762 MC1742
MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 ...
T37536 Carbazomycin A
Carbazomycin A is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities.1,2It is active againstS. aureus,T. asteroides, andT. mentagrophytes(MIC = 12.5 μg/ml for all), as well a...
T36929 Pal-KTTKS (acetate)
Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when use...
T36679 Rp-cAMPS sodium salt
Rp-cAMPS sodium salt, a cAMP analog, is a potent, competitive cAMP-induced activation of cAMP-dependent PKA I and II (Kis of 12.5 μM and 4.5 μM, respectively) antagonist. Rp-cAMPS sodium salt is resistant to hydrolysis b...
T38284 C24 dihydro 1-Deoxyceramide (m18:0/24:0) C24 dihydro 1-Deoxyceramide (m18:0/24:0)
C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
T83765 Dendrogenin A ​DDA
Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest...
T38280 C22 dihydro 1-Deoxyceramide (m18:0/22:0) C22 dihydro 1-Deoxyceramide (m18:0/22:0)
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
T38214 1-Deoxysphingosine (m18:1(4E)) 1-Deoxysphingosine (m18:1(4E))
1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine durin...
T36892 4'-Acetyl Chrysomycin A
4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS....

Compounds

R 59-022 hydrochloride
T72322
Synonym: DKGI-I hydrochloride,Diacylglycerol kinase inhibitor I hydrochloride,DKGI-I hydrochloride ; Diacylglycerol kinase inhibitor I hydrochloride
Target: 5-HT Receptor, PKC
R 59-022
T16709
Synonym: Diacylglycerol kinase inhibitor I,DKGI-I
Target: Others
RSVA405
T8476
Synonym: RSVA 405
Target: AMPK, STAT, Autophagy
Ipratropium Bromide
T6547
Synonym: Sch 1000,Itrop,Atrovent
Target: AChR
Nitrosoglutathione
T19930
Synonym: S-Nitrosoglutathione,SNOG,Glutathione thionitrite,GSNO
Target: RAAS, NO Synthase
Ipratropium bromide monohydrate
T0098
Synonym: Ipratropium bromide hydrate
Target: AChR
SYBR GREEN 1
TD0001
Synonym: SYBR(R) GREEN I NUCLEIC ACID GEL STAIN *10,000× concentrate in DMSO
Target: Others
Etomoxir sodium salt
T4535
Synonym: (R)-Etomoxir sodium salt,Na salt,Etomoxir
Target: Apoptosis, Others
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
ANR 94
T22031
Synonym:
Target: Adenosine Receptor
Multi-kinase inhibitor 1
T4191
Synonym: Multi-kinase inhibitor I
Target: Others, Bcr-Abl, PDGFR, c-Kit
Clometocillin
T30981
Synonym: Penicilline 356
Target:
KU14R
T15672
Synonym:
Target: Others
ML 7
T33451
Synonym: ML7,ML-7
Target:
(R)-ND-336
T61491
Synonym:
Target:
5-HT7R antagonist 1 free base
T39870
Synonym: 5-HT7R antagonist 1 free base
Target:
hCAII-IN-7
T74331
Synonym:
Target:
(R)-SLV 319
T22140
Synonym:
Target:
MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan
T74723
Synonym:
Target:
Carbonic anhydrase inhibitor 8
T61980
Synonym:
Target:
Tricarbonyldichlororuthenium(II) dimer
T39795
Synonym: CORM-2
Target:
Human carbonic anhydrase II-IN-2
T61982
Synonym:
Target:
GSK-598809
T71001
Synonym:
Target:
(R)-Lanicemine
T73682
Synonym:
Target:
Anti-MI/R injury agent 1
T83043
Synonym:
Target:
3-hydroxy Palmitic Acid methyl ester
T37680
Synonym:
Target:
RIPK3-IN-4
T81267
Synonym:
Target: RIP kinase
MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan
T74724
Synonym:
Target:
Neuropeptide Y Y1 receptor antagonist 1
T74350
Synonym:
Target:
NH2-c[X-R-L-S-X]-K-G-P-(D-1Nal)
T76223
Synonym:
Target:
(D-Arg8)-Inotocin
T80138
Synonym:
Target: Vasopressin Receptor
CU-76
T38329
Synonym:
Target:
1-Heptadecanoyl-rac-glycerol
T37887
Synonym:
Target:
CU-32
T38328
Synonym:
Target:
ADRA1D receptor antagonist 1 free base
T72091
Synonym:
Target:
Efonidipine hydrochloride
T72213
Synonym: NZ-105 hydrochloride
Target:
MC1742
T35762
Synonym:
Target:
Carbazomycin A
T37536
Synonym:
Target:
Pal-KTTKS (acetate)
T36929
Synonym:
Target:
Rp-cAMPS sodium salt
T36679
Synonym:
Target:
C24 dihydro 1-Deoxyceramide (m18:0/24:0)
T38284
Synonym: C24 dihydro 1-Deoxyceramide (m18:0/24:0)
Target:
Dendrogenin A
T83765
Synonym: ​DDA
Target:
C22 dihydro 1-Deoxyceramide (m18:0/22:0)
T38280
Synonym: C22 dihydro 1-Deoxyceramide (m18:0/22:0)
Target:
1-Deoxysphingosine (m18:1(4E))
T38214
Synonym: 1-Deoxysphingosine (m18:1(4E))
Target:
4'-Acetyl Chrysomycin A
T36892
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TN1895 Luteolinidin chloride CD38
Luteolinidin chloride is a natural product. It is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo.
T2961 Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1 Apoptosis , ERK , Beta Amyloid
Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.
T21328 Carubicin carminomycin,Carminomycin I,Carminomicin I,Antibiotic R 588A,Demethyldaunomycin
Carubicin is an anthracycline antineoplastic antibiotic isolated from the bacterium Actinomadura carminata. Carubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repa...
TN5997 Stipuleanoside R1 Tarasaponin I
Stipuleanoside R1 is a natural product for research related to life sciences. The catalog number is TN5997 and the CAS number is 96627-79-1.
T5S1262 Methylophiopogonanone A Others
1. Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties. 2. Methylophiopogonanone A has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulati...
T5S1632 Barlerin 8-O-Acetylshanzhiside methyl ester,ND01 VEGFR , TNF , NF-κB , Akt , Caspase
Barlerin (8-O-Acetylshanzhiside methyl ester) has potential against cerebral ischemic injury, and its protective effect on oxygen-glucose deprivation-induced injury might be due to the suppression of intracellular Ca2+ e...
T3753 Sinapinic Acid Sinapic acid,Synapoic acid Apoptosis , RAAS , Reactive Oxygen Species , HDAC
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...
T6S1369 Vitexin Apigenin-8-C-glucoside Antioxidant
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...
T3893 Forsythoside B TNF , NF-κB
Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effect...
T5S0053 Coptisine Coptisin Indoleamine 2,3-Dioxygenase (IDO)
1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...
T13576 β-cyano-L-Alanine Beta-cyano-l-alanine Others
β-cyano-L-Alanine (Beta-cyano-l-alanine) is a nitrile of widespread occurrence in higher plants.
T4S2326 Cornuside 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside ERK , p38 MAPK , NF-κB , JNK
1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...
T3895 Polyphyllin I Apoptosis , Akt , JNK , PDK , mTOR , Autophagy
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha...
T40576 (S)-Salsolidine
(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boast...
TN3914 Echinatine ATPase , IL Receptor , TNF
Echinatin exerts a protective effect against ischemia/reperfusion (I/R)-induced myocardial injury on hearts, this effect may be attributed to the antioxidant and anti-inflammatory activities of this compound. Echinatin c...
T19169 9-cis-Retinal Others
9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to CRBP-I and CRBP-II (Kds: 8 nM and 5 nM). It expedites differentiation and ma...
T36000 3-Hydroxyterphenyllin
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00834 IGF1R/CD221 Protein, Human, Recombinant (His) Human HEK293
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-02535 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPK-00455 IGF1R/CD221 Protein, Human, Recombinant (His & Avi) Human HEK293
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00456 IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated Human HEK293
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00658 IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPY-06905 IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-04360 IGF1R/CD221 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-05475 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01639 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) Mouse HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-01618 GLO1 Protein, Mouse, Recombinant (His) Mouse E. coli
Lactoylglutathione lyase, also known as Methylglyoxalase, Aldoketomutase, Glyoxalase I, Ketone-aldehyde mutase, S-D-lactoylglutathione methylglyoxal lyase and GLO1, is a member of the glyoxalase I family. GLO1 / Glyox...
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-04643 Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) Mouse HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-05636 G-CSF Protein, Mouse, Recombinant Mouse HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829 G-CSF Protein, Human, Recombinant Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPJ-00781 LR3-IGF-1 Protein, Mouse, Recombinant (His) Mouse E. coli
Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-termin...
TMPK-00320 IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi) Human HEK293
IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region...
TMPK-00321 IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
IL-2 R beta is a member of the cytokine receptor superfamily. Human IL-2 R beta cDNA encodes a 551 amino acid residue precursor Type I membrane protein with a 26 residue signal peptide, a 214 residue extracellular region...
TMPJ-00411 LEPR Protein, Human, Recombinant (hFc) Human Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00977 LEPR Protein, Mouse, Recombinant (mFc) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00975 LEPR Protein, Mouse, Recombinant (hFc) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-00976 LEPR Protein, Mouse, Recombinant (His) Mouse Human Cells
The Leptin receptor is a member of the Class I cytokine receptor family. It mediates the activities of Leptin, a multi-functional hormone produced primarily by adipose tissues that plays roles in food intake, energy meta...
TMPJ-01159 CD16/FCGR3 Protein, Mouse, Recombinant (His) Mouse Human Cells
Low affinity immunoglobulin gamma Fc region receptor III (Fc gamma RIII/CD16) is a member of the Ig superfamily. Based on close relationships in their extracellular domains, the Fc gamma Rs have been divided into three c...
TMPJ-01056 IL-18 Protein, Mouse, Recombinant (His) Mouse E. coli
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63...
TMPJ-01337 IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Mouse Human Cells
Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also f...
TMPJ-00129 BTLA Protein, Human, Recombinant (His) Human Human Cells
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed...
TMPJ-00091 G-CSF Protein, Mouse, Recombinant (His) Mouse Human Cells
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis ...
TMPH-02801 CYPOR Protein, Mouse, Recombinant (His) Mouse E. coli
Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. I...
TMPH-01133 Complement C8b Protein, Human, Recombinant (His) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPH-01134 Complement C8g Protein, Human, Recombinant (His) Human E. coli
Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translatio...
TMPY-01052 R-Cadherin/CDH4 Protein, Human, Recombinant (His) Human HEK293
The cadherin superfamily is a large family that engage in both homo- and heterotypic, calcium-dependent, cell-cell adhesion events, and can be divided into at least four subfamilies based on the extracellular (EC) region...
TMPY-00813 G-CSF Protein, Human, Recombinant (hFc) Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
IGF1R/CD221 Protein, Human, Recombinant (His)
TMPY-00834
Species: Human
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
TMPY-01459
Species: Human
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)
TMPY-02535
Species: Mouse
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
TMPK-00455
Species: Human
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
TMPK-00456
Species: Human
Expression System: HEK293
IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
TMPK-00658
Species: Cynomolgus
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06905
Species: Human
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His & GST)
TMPY-04360
Species: Human
Expression System: Baculovirus-Insect Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc)
TMPY-05475
Species: Human
Expression System: HEK293
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)
TMPY-01639
Species: Mouse
Expression System: HEK293
GLO1 Protein, Mouse, Recombinant (His)
TMPY-01618
Species: Mouse
Expression System: E. coli
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
TMPY-04643
Species: Mouse
Expression System: HEK293
G-CSF Protein, Mouse, Recombinant
TMPY-05636
Species: Mouse
Expression System: HEK293
G-CSF Protein, Human, Recombinant
TMPY-04829
Species: Human
Expression System: HEK293
LR3-IGF-1 Protein, Mouse, Recombinant (His)
TMPJ-00781
Species: Mouse
Expression System: E. coli
IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi)
TMPK-00320
Species: Human
Expression System: HEK293
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
TMPK-00321
Species: Cynomolgus
Expression System: HEK293
LEPR Protein, Human, Recombinant (hFc)
TMPJ-00411
Species: Human
Expression System: Human Cells
LEPR Protein, Mouse, Recombinant (mFc)
TMPJ-00977
Species: Mouse
Expression System: Human Cells
LEPR Protein, Mouse, Recombinant (hFc)
TMPJ-00975
Species: Mouse
Expression System: Human Cells
LEPR Protein, Mouse, Recombinant (His)
TMPJ-00976
Species: Mouse
Expression System: Human Cells
CD16/FCGR3 Protein, Mouse, Recombinant (His)
TMPJ-01159
Species: Mouse
Expression System: Human Cells
IL-18 Protein, Mouse, Recombinant (His)
TMPJ-01056
Species: Mouse
Expression System: E. coli
IL-21R Protein, Mouse, Recombinant (aa 20-236, His)
TMPJ-01337
Species: Mouse
Expression System: Human Cells
BTLA Protein, Human, Recombinant (His)
TMPJ-00129
Species: Human
Expression System: Human Cells
G-CSF Protein, Mouse, Recombinant (His)
TMPJ-00091
Species: Mouse
Expression System: Human Cells
CYPOR Protein, Mouse, Recombinant (His)
TMPH-02801
Species: Mouse
Expression System: E. coli
Complement C8b Protein, Human, Recombinant (His)
TMPH-01133
Species: Human
Expression System: E. coli
Complement C8g Protein, Human, Recombinant (His)
TMPH-01134
Species: Human
Expression System: E. coli
R-Cadherin/CDH4 Protein, Human, Recombinant (His)
TMPY-01052
Species: Human
Expression System: HEK293
G-CSF Protein, Human, Recombinant (hFc)
TMPY-00813
Species: Human
Expression System: HEK293
Cat No. Product Name
L4100 TGF-beta/Smad Compound Library

185 compounds
A unique collection of 185 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;
TargetMol