474
101
33
1
3
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6584 | MG 149 | MG149,Tip60 HAT inhibitor | Apoptosis , Others , Epigenetic Reader Domain , Histone Acetyltransferase |
MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM). | |||
T11537 | HAT-IN-1 | Others | |
HAT-IN-1 is an inhibitor of HAT used in the research of cancer. | |||
T79253 | HAT-IN-8 | Parasite | |
HAT-IN-8 (Compound 38), a blood-brain barrier-permeable inhibitor of Trypanosoma brucei with an EC50 of 0.18 μM, is utilized in the study of Human African trypanosomiasis [1]. | |||
T74800 | HAT-SIL-TG-1&AT | ||
HAT-SIL-TG-1&AT, a hypoxia-activated prodrug, functions as a Janus tyrosine kinase (JAK) inhibitor demonstrating antitumor effects by inhibiting JAK-STAT signaling within tumor tissues. It also suppresses the proliferati... | |||
T3499 | Remodelin | Histone Acetyltransferase | |
Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10. | |||
T12098 | MOZ-IN-2 | Histone Acetyltransferase | |
MOZ-IN-2 is an protein MOZ inhibitor(IC50 of 125 μM). | |||
T5468 | YF-2 | Others , Epigenetic Reader Domain , Histone Acetyltransferase | |
YF-2 is blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, CBP, PCAF, and GCN5 with EC50s of 2.75 μM, 29.04 μM and 49.31 μM , respectively | |||
T4679 | WM-1119 | WM1119 | Histone Acetyltransferase |
WM-1119 is a highly potent, selective KAT6A/B inhibitor | |||
T15216 | EML 425 | Epigenetic Reader Domain , Histone Acetyltransferase | |
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)/p300 (IC50s: 2.9 and 1.1 μM, respectively). | |||
T15405 | GNE-781 | Epigenetic Reader Domain | |
GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET assay). GNE-781 also inhibits BRET and BRD4(1) (IC50s: 6.2 nM and 5100 nM, respectively). | |||
T14073 | A-485 | Epigenetic Reader Domain , Histone Acetyltransferase | |
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively). | |||
T2452 | C646 | Apoptosis , Epigenetic Reader Domain , Histone Acetyltransferase , Autophagy | |
C646, a histone acetyltransferase inhibitor, inhibits p300 (Ki: 400 nM, in a cell-free assay). | |||
T6811 | CPI-637 | CPI 637 | Epigenetic Reader Domain , Histone Acetyltransferase |
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor. | |||
T11563 | Histone Acetyltransferase Inhibitor II | Epigenetic Reader Domain , Histone Acetyltransferase | |
Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activity in mammalian cells. | |||
T11807 | L002 | Others , Histone Acetyltransferase , STAT | |
L002, a potent, cell-permeable, reversible, and specific acetyltransferase p300 (KAT3B) inhibitor with an IC50 of 1.98 μM, directly binds the acetyl-CoA pocket and competitively inhibits the FATp300 catalytic domain. By ... | |||
T8344 | CPTH2 | Apoptosis , Histone Acetyltransferase | |
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network. | |||
T3969 | I-CBP112 | Epigenetic Reader Domain , Histone Acetyltransferase | |
I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains. | |||
T6133 | Remodelin hydrobromide | Remodelin,Remodelin HBR | RAAS , Histone Acetyltransferase |
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10. | |||
T9541 | CTB | Cholera Toxin B subunit | Epigenetic Reader Domain |
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells. | |||
T4362 | WM-8014 | MOZ-IN-3 | Histone Acetyltransferase |
WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases. | |||
T2112 | Fexinidazole | HOE 239 | Others , Parasite |
Fexinidazole (HOE 239) is an antiparasitic agent. It has activity against Trypanosoma cruzi, Tritrichomonas foetus, Trichomonas vaginalis, Entamoeba histolytica, Trypanosoma brucei, and Leishmania donovani. The biologica... | |||
T6908 | NSC 228155 | NSC228155 | EGFR , Epigenetic Reader Domain , DNA/RNA Synthesis , Histone Acetyltransferase |
NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation. | |||
T8778 | TTK21 | Epigenetic Reader Domain | |
TTK21 is an activator of CBP/p300 histone acetyltransferase activity. | |||
T6668 | SGC-CBP30 | Epigenetic Reader Domain , Histone Acetyltransferase | |
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM). | |||
T12345 | CBP/p300-IN-3 | P300/CBP-IN-3 | Histone Acetyltransferase |
CBP/p300-IN-3 (P300/CBP-IN-3) is an inhibitor of p300/CBP histone acetyltransferase. | |||
T7856 | Naphthol AS-E | nAS-E | Epigenetic Reader Domain , Histone Acetyltransferase |
Naphthol AS-E (nAS-E) is an the KIX-KID interaction and CREB-mediated gene transcription inhibitor. | |||
T9102 | WM-3835 | Apoptosis , Histone Methyltransferase , Histone Acetyltransferase | |
WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation. | |||
T8658 | NEO2734 | EP31670 | Epigenetic Reader Domain , Histone Acetyltransferase |
NEO2734 (EP31670) is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of <30 nM for both p300/CBP and BET bromodomains). | |||
T9167 | PF-9363 | CTX-3648 | Histone Acetyltransferase |
PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer. | |||
T3217 | PF-CBP1 hydrochloride | PF-CBP1 HCl | Epigenetic Reader Domain , Histone Acetyltransferase |
PF-CBP1 hydrochloride (PF-CBP1 HCl) is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP).It inhibits CREBBP and p300 bromodomains with IC50 of 125 and 363 nM respectively. | |||
T9373 | DCH36_06 | (5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione | Apoptosis , Epigenetic Reader Domain , Histone Acetyltransferase |
DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) as a bona fide is a potent p300/CBP inhibitor | |||
T11013L2 | Levorotation nimorazole phosphate ester TFA | Others | |
Levorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent. | |||
T40781L | Geranylgeranyl pyrophosphate tetrabutylammonium(1:1.5) | Others | |
(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) is a common precursor of taxadiene such as Paclitaxel. | |||
T27400L | Ganaplacide phosphate | Ganaplacide phosphate (1261113-96-5 Free base) | Others |
Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models. | |||
T5007 | Benproperine phosphate | Blascorid,Pirexyl phosphate | Others , Microtubule Associated |
Benproperine phosphate (Pirexyl phosphate) is a cough suppressant. | |||
T19389 | L-Ascorbic acid 2-phosphate magnesium | 2-Phospho-L-ascorbic acid magnesium | Phosphatase , Phosphorylase |
L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production.It is a long-acting vitamin C derivative that can stimulate... | |||
T7518 | Deoxycytidine triphosphate trisodium salt | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite , Antibiotic |
Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria. | |||
T6998 | Tedizolid Phosphate | TR-701FA,Torezolid phosphate | Antibacterial , Antibiotic |
Tedizolid Phosphate (TR-701FA) is an oxazolidinone-class antibiotic. Tedizolid phosphate is a phosphate ester prodrug of the active compound tedizolid. | |||
T1486 | Oseltamivir phosphate | GS 4104 | Influenza Virus |
Oseltamivir phosphate (GS 4104) is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. By blocking neuraminidases on the surfaces of influenza viruses, oseltamivir in... | |||
T40781L1 | Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) | Geranylgeranyl pyrophosphate tetrabutylammonium(1:2)(6699-20-3 Free base) | Others |
Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is one of the endogenous cholesterol and intermediates produced by the mevalerate pathway. Geranylgeranyl pyrophosphate tetrabutylammonium(1:2) is the common precursor... | |||
T7394 | Toceranib Phosphate | SU11654 phosphate,PHA 291639 phosphate | VEGFR , Tyrosinase , PDGFR , c-Kit |
Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family, including Flk-1/KDR, PDGFR | |||
T0850 | Primaquine diphosphate | Primaquine phosphate,Primaquine bisphosphate | Antibiotic , Parasite |
Primaquine diphosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the proper... | |||
T16697 | Pyronaridine tetraphosphate | Topoisomerase | |
Pyronaridine tetraphosphate is an orally active, mannitol-containing inhibitor of DNA topoisomerase 2 and erythrocyte cytokine with antimalarial and antitumour activity.Pyronaridine tetraphosphate treats P. falciparum an... | |||
T21195 | AICAR monophosphate | Aica ribonucleotide,AICA riboside,Acadesine 5'-monophosphate,Z-nucleotide | Others |
AICAR monophosphate (Aica ribonucleotide) is a purine precursor with antineoplastic activity and can be used in studies about type 2 diabetes. | |||
T18888 | 4-Methylumbelliferyl phosphate | 4-MUP | Others |
4-Methylumbelliferyl phosphate (4-MUP) (4-MUP) is used as a fluorogenic substrate of alkaline phosphatases. | |||
T23358 | Sitagliptin phosphate | Januvia,MK-0431 phosphate,Sitagliptin (phosphate) | DPP-4 , Autophagy |
Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor. | |||
T65012 | Bis(4-nitrophenyl) phosphate | BNPP | Others |
Bis(4-nitrophenyl) phosphate (BNPP) inhibits UDP-galactose and can be used to study glycosyltransferase membrane topology. | |||
T20048 | Vidarabine phosphate | Antiviral | |
Vidarabine phosphate is an adenosine monophosphate analog. It is the monophosphate ester of VIDARABINE. It also has antiviral and possibly antineoplastic properties. | |||
T2606 | KN-93 Phosphate | CaMK | |
KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II with K i of 370 nM. KN-93 phosphate inhibits serum-induced fibroblast cell growth in a comparable dose-dependent fashion to it... | |||
T4530 | KN-92 phosphate | KN92-H3PO4 | CaMK |
KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11366 | Garcinol | Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE | |
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone... | |||
TN1150 | Procyanidin B3 | Histone Acetyltransferase | |
Procyanidin B3(B3) is a procyanidin dimer that is widely studied due to its high abundance in the human diet and antioxidant activity. | |||
T6389 | Anacardic Acid | 6-pentadecylsalicylic Acid,Hydroginkgolic acid | Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial |
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland... | |||
T0065 | Acetaminophen | 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol | COX , Endogenous Metabolite , Histone Acetyltransferase |
Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity. | |||
T1516 | Curcumin | Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow | Mitophagy , Epigenetic Reader Domain , Ferroptosis , Influenza Virus , Nrf2 , Histone Acetyltransferase , HDAC , Autophagy |
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, ant... | |||
T8186 | Xanthosine 5'-monophosphate sodium salt | XMP,L-XMP Sodium | Others |
Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism. | |||
T5073 | Inosine 5'-monophosphate disodium salt hydrate | Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,Disodium 5'-inosinate monohydrate | Others , Endogenous Metabolite |
Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis. | |||
T5288 | Cytidine-5'-triphosphate disodium | CTP,Cytidine 5'-triphosphate (disodium salt) | Others , Endogenous Metabolite |
Cytidine-5'-triphosphate disodium (CTP) is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. Cytidine-5'-triphosphate disodium is used in the synthesis of RNA by RNA polymerases... | |||
T8083 | Pyridoxal 5'-phosphate monohydrate | Pyridoxal phosphate monohydrate,Pyridoxal 5-phosphate monohydrate | Others |
Pyridoxal 5'-phosphate monohydrate is an active vitamin B6 metabolite | |||
T5065 | GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD | Monosodium-GMP,cGMP sodium salt,Cyclic GMP | PKA |
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SOD (cGMP sodium salt) , also known as cGMP, is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, inc... | |||
T37984 | D-Fructose-1,6-bisphosphate sodium salt hydrate | Others | |
D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by ph... | |||
T2185 | L-Ascorbic acid 2-phosphate trisodium | L-Ascorbic acid 2-phosphate trisodium salt,Sodium L-ascorbyl-2-phosphate,Sodium ascorbyl phosphate,2-Phospho-L-ascorbic acid trisodium salt,Sodium ascorbyl monophosphate | Reactive Oxygen Species , c-Met/HGFR , Endogenous Metabolite |
L-Ascorbic acid 2-phosphate trisodium (Sodium ascorbyl phosphate) is used in biocatalytic dephosphorylation for electric power generation and electrochemical detection assays. | |||
T5S0814 | Berberine hydrogen sulphate | Berberine Bisulfate,Umbellatine Sulfate | Antibacterial |
Berberine hydrogen sulphate (Umbellatine Sulfate) , an alkaloid extracted from several plants, possesses antimicrobial activity against a wide variety of microorganisms including Gram-positive and Gram-negative bacteria,... | |||
T0194 | Chloroquine phosphate | Chloroquine diphosphate,Aralen phosphate,Chingamin phosphate | SARS-CoV , TLR , HIV Protease , Antibiotic , Parasite , Autophagy |
Chloroquine phosphate (Aralen phosphate) is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). | |||
T0853L | Adenosine 5'-monophosphate monohydrate | 5'-AMP,5'-AMP monohydrate,5'-Adenylic acid | AMPK , Adenosine Receptor , HSV |
Adenosine 5'-monophosphate monohydrate (5'-AMP) , also known as 5'-adenylic acid, is a nucleotide that is used as a monomer in RNA. It is an ester of phosphoric acid and the nucleoside adenosine. Adenosine 5'-monophospha... | |||
T19514 | Phosphatidylcholines,soya | Soybean phosphatidylcholine | Others |
Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes. | |||
T4739 | Sodium creatine phosphate dibasic tetrahydrate | Creatine phosphate disodium salt tetrahydrate | Others , Endogenous Metabolite |
Sodium creatine phosphate dibasic tetrahydrate (Creatine phosphate disodium salt tetrahydrate) mainly exists in the skeletal muscles of vertebrates. It is a substrate for the determination of creatine kinase and can be u... | |||
T5069 | D-Glucose 6-phosphate potassium salt | Others | |
D-Glucose 6-phosphate potassium is the potassiu salt form of D-glucose 6-phosphate, which is a glucose sugar phosphorylated at the hydroxy group on carbon 6. | |||
T7520 | Deoxycytidine triphosphate | Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite | |
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. | |||
T2133 | Adenosine monophosphate | 5'-Adenylic acid,AMP,Adenosine 5'-monophosphate | Endogenous Metabolite , AMPK |
Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatas... | |||
T4969 | Guanosine 5'-triphosphate trisodium salt | GTP Trisodium salt,5'-GTP trisodium salt | Endogenous Metabolite |
Guanosine 5'-triphosphate trisodium salt (5'-GTP trisodium salt) activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of se... | |||
T4972 | 2'-Deoxycytidine-5'-diphosphate trisodium | dCDP | Endogenous Metabolite |
2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) is used as a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6) for the production of dCTP to support DNA biosynthesis and reverse transcription. | |||
T40426 | Cytidine 5'-diphosphate trisodium salt | CDP | Others |
Cytidine 5'-diphosphate trisodium salt (CDP) can produce Cytidine triphosphate for synthesis of DNA and RNA through the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosp... | |||
T4924 | α-D-Glucose-1-phosphate disodium | α-D-Glucose 1-phosphate disodium salt hy,α-D-Glucopyranose 1-phosphate | Others , Endogenous Metabolite |
α-D-Glucose 1-phosphate disodium salt is converted into D-glucose-6-phosphate by the enzyme phosphoglucomutase. | |||
T37635 | 2'-Deoxyadenosine-5'-triphosphate trisodium | dATP trisodium | DNA/RNA Synthesis , Endogenous Metabolite |
2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication. | |||
T4925 | Thiamine monophosphate chloride (dihydrate) | Thiamine monophosphate chloride dihydrat,Aneurine monophosphate chloride | Others , Endogenous Metabolite |
Thiamine monophosphate chloride dihydrate (Aneurine monophosphate chloride) is a compound used in the screening of ligands that promote protein stability | |||
T4718 | Uridine 5'-monophosphate | Uridylic acid,UMP,Uridine phosphate,Uridine 5'-phosphoric acid,5'-Uridylic acid | Others , Endogenous Metabolite |
5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. Uridine 5'-monophosphate (Uridylic acid) is a nucleotide that is found in RNA. It is an es... | |||
T4726 | D-Glucose 6-phosphate sodium | G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate | Others , Endogenous Metabolite |
In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the begi... | |||
T5085 | Pyridoxal 5'-phosphate hydrate | Codecarboxylase,Pyridoxal 5'-phosphate hydrate(1:x),PLP,Pyridoxal 5'-phosphate hydrate | Others , Endogenous Metabolite |
Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions, including mitochondrial cysteine desulfurase, cystathionine γ-synth... | |||
T4874 | Thiamine pyrophosphate | Cocarboxylase,Aneurinepyrophosphoric acid,Thiamine pyrophosphate chloride | Endogenous Metabolite |
Thiamine pyrophosphate (Cocarboxylase) is a vitamin B-1 derivative that acts as a coenzyme of transketolase. Thiamine pyrophosphate is used in studies to assess decarboxylation mechanisms in biological systems. | |||
T3501 | Colistimethate Sodium | Colistin-1,3,5,9-tetramethanesulfonic A acid | Others |
Colistin-1,3,5,9-tetramethanesulfonic A acid is used for the treatment of serious infections due to selected aerobic Gram-negative pathogens in patients with limited treatment options. | |||
T4735 | 2'-Deoxyuridine 5'-monophosphate disodium | 2'-dUMP⋅2Na,2'-Deoxyuridine 5'-monophosphate disodium salt | Others , Endogenous Metabolite |
2'-Deoxyuridine 5'-monophosphate disodium (2'-dUMP⋅2Na) salt is used by the enzyme thymidylate synthetase (TS) for the de novo production of dTMP. dUMP is used as the reference substrate in studies of dUMP analogues in p... | |||
T7192 | Diethyl phosphate | Diethyl phosphoric acid | Others , Endogenous Metabolite |
Diethyl phosphate (Diethyl phosphoric acid), a Non-Specific Metabolite of Organophosphorus Pesticides. | |||
T10005L | 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium | Endogenous Metabolite | |
1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium, a phosphatidic acid, is a human endogenous metabolite. | |||
T19281L | Dihydroxyacetone phosphate hemimagnesium salt hydrate | Dihydroxyacetone phosphate hemimagnesium salt hydrate(57-04-5 free base) | Others |
Dihydroxyacetone phosphate hemimagnesium salt hydrate is a member of the class of glycerone phosphates that consists of glycerone bearing a single phospho substituent. It has a role as a human metabolite, a Saccharomyces... | |||
T13206 | Tris(2,4-di-tert-butylphenyl)phosphate | Phospholipase | |
Tris(2,4-di-tert-butylphenyl)phosphate is a natural compound isolated from Vitex negundo L. with anti-inflammatory activity. | |||
T14149 | AICAR phosphate | AICA Riboside phosphate,Acadesine phosphate | Mitophagy , NOS , YAP , AMPK |
AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in... | |||
T9171 | Methenolone enanthate | Others | |
Methenolone enanthate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. | |||
T9086 | Deoxythymidine-5'-triphosphate trisodium | dTTP trisodium salt,thymidine 5'-(trisodium hydrogen triphosphate),Deoxythymidine-5'-triphosphate (dTTP) trisodium salt | DNA/RNA Synthesis |
Deoxythymidine-5'-triphosphate trisodium (Deoxythymidine-5'-triphosphate (dTTP) trisodium salt) is one of the four natural deoxynucleotides. It is used for the biosynthesis of deoxyribonucleic acid by DNA polymerase and ... | |||
T7989 | Trimethyl phosphate | Others | |
Trimethyl phosphate is an organophosphorus compound that is an inhibitor of enzymes that catalyze the hydrolysis of phosphorylated compounds. It has been used as a reactant in the synthesis of peptides and other proteins... | |||
T4730 | Thymidine-5'-monophosphate disodium salt | Thymidine 5'-monophosphate disodium salt,TMP DISODIUM SALT | Others , Endogenous Metabolite |
Thymidine-5'-monophosphate disodium salt (TMP DISODIUM SALT) is found in DNA. In mammalian cells, thymidine deprivation induces chromosome aberrations such as chromatid breaks, chromatid interchanges, and chromosome frag... | |||
T4897 | Inosine-5'-triphosphate trisodium salt | ITP,Inosine 5'-triphosphate trisodium salt | Others , Endogenous Metabolite |
Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substra... | |||
T1331 | Riboflavin phosphate sodium | Riboflavin 5'-phosphate sodium,Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,FMN-Na,riboflavin-5'-phosphate | Endogenous Metabolite |
Riboflavin phosphate sodium (FMN) is the phosphate sodium salt form of riboflavin, a water-soluble and essential micronutrient that is the principal growth-promoting factor in naturally occurring vitamin B complexes. Rib... | |||
T7210 | Guanosine 5'-diphosphate | GDP | Endogenous Metabolite |
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. | |||
TMA2440 | Uridine 5'-monophosphate disodium salt | Disodium UMP,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate | Others |
Uridine 5'-monophosphate disodium salt (Disodium UMP) has been used to study the effect of pyrimidine synthesis inhibitor, 5-azacytidine, on cholesterol and lipid metabolism. It has been used to study the effect of nucle... | |||
T4942 | Galactose 1-phosphate Potassium salt | α-D-Galactose-1-phosphate Dipotassium Pentahydrate | Others , Endogenous Metabolite |
Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways. | |||
T19343 | Sn-Glycerol 3-phosphate | Glycerol 3-phosphate,sn-Glycerol 3-phosphate lithium salt | Endogenous Metabolite |
sn-Glycerol 3-phosphate is produced by the reduction of dihydroxyacetone phosphate by NADH formed during glycolysis of the cytoplasmic glycerol 3-phosphate dehydrogenase pathway. | |||
T19262 | D-Glucose 6-phosphate disodium salt | D-Glucose 6-phosphate disodium salt | Endogenous Metabolite |
D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic re... | |||
T4706 | Uridine-5'-diphosphate disodium salt | UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd | DNA/RNA Synthesis , Endogenous Metabolite , P2Y Receptor |
Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction... | |||
T5213 | Acetyl phosphate(lithium potassium) | Lithium potassium acetyl phosphate,Acetylphosphoric acid | Others , Endogenous Metabolite |
Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04985 | TMPRSS11D Protein, Human, Recombinant (His) | Human | HEK293 |
TMPRSS11D (HAT) belongs to the large type II transmembrane serine protease (TTSP) family, participating in various biological and physiological processes. TMPRSS11D protein expression in tumorous tissues were correlated ... | |||
TMPY-00663 | Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-02650 | Alkaline phosphatase Protein, Human, Recombinant (His) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | Yeast |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPK-00639 | Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) | Rat | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00801 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00802 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00684 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00804 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00803 | Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-02155 | Prostatic Acid Phosphatase Protein, Human, Recombinant (His) | Human | HEK293 |
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized... | |||
TMPH-00568 | 8-oxo-dGTP diphosphatase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Specifically hydrolyzes both 8-oxo-deoxyguanosine triphosphate (8-oxo-dGTP) and 8-oxo-guanosine triphosphate (8-oxo-GTP) to the related monophosphates, thereby cleaning up the nucleotide pools and preventing misincorpora... | |||
TMPH-00685 | Exopolyphosphatase Protein, E. coli O6:H1, Recombinant (His) | E. coli | E. coli |
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. | |||
TMPH-01085 | CHAT Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses. | |||
TMPY-00594 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPY-02131 | Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST) | Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im... | |||
TMPY-00446 | Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is cal... | |||
TMPK-01326 | Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-02672 | Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized... | |||
TMPJ-00784 | Alkaline Phosphatase Protein, Human, Recombinant (aa 23-506, His) | Human | Human Cells |
ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a rol... | |||
TMPJ-01203 | HATL5 Protein, Human, Recombinant (His) | Human | Human Cells |
Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease tha... | |||
TMPH-03161 | Alkaline Phosphatase Protein, Prevotella intermedia, Recombinant (GST & His & Myc) | Prevotella intermedia | E. coli |
Acts against tyrosine-phosphatases. | |||
TMPH-00713 | Polyphosphate kinase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Can form linear polymers of orthophosphate with chain lengths up to 1000 or more. Can use GTP instead of ATP,... | |||
TMPH-00673 | NADH pyrophosphatase Protein, E. coli O157:H7, Recombinant (His) | E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph... | |||
TMPH-00609 | DITP/XTP pyrophosphatase Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinos... | |||
TMPK-00855 | Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPK-00796 | Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) | Human | HEK293 |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase ... | |||
TMPY-02713 | Alkaline phosphatase Protein, Human, Recombinant (hFc) | Human | HEK293 |
ALPI encodes for intestinal phosphatase alkaline, a brush border metalloenzyme that hydrolyses phosphate from the lipid A moiety of lipopolysaccharides and thereby drastically reduces Toll-like receptor 4 agonist activit... | |||
TMPY-03755 | Glycerol 3 Phosphate Dehydrogenase/GPD1 Protein, Human, Recombinant (His) | Human | E. coli |
GPD1 (Glycerol-3-Phosphate Dehydrogenase 1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. GPD1 is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encode... | |||
TMPH-03455 | Polyphosphatase/PPX1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Degradation of inorganic polyphosphates. | |||
TMPH-03236 | Alkaline phosphatase/ALPL Protein, Rat, Recombinant (His & SUMO) | Rat | E. coli |
Alkaline phosphatase that metabolizes various phosphate compounds and plays a key role in skeletal mineralization and adaptive thermogenesis. Has broad substrate specificity and can hydrolyze a considerable variety of co... | |||
TMPH-00618 | Exopolyphosphatase Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Degradation of inorganic polyphosphates (polyP). Releases orthophosphate processively from the ends of the polyP chain. Has a strong preference for long-chain polyphosphates and has only weak affinity for smaller size po... | |||
TMPH-01239 | XPC Protein, Human, Recombinant (His) | Human | E. coli |
Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B an... |
Cat No. | Product Name | ||
---|---|---|---|
L9100 | Phosphatase Inhibitor Library | 80 compounds | |
A collection of 80 phosphatase inhibitors with known activity; |