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Search Result

Search Results for " gsk-a-1 "

Targets

HCV Protease PI4K

49

Compounds

3

Natural Products

1733

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T27499 GSK-A1 HCV Protease , PI4K
GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression. GSK-A1 has anti-hepatitis C virus (HCV) potential.
T1906 Molibresib GSK 525762A,GSK525762,I-BET 762 Epigenetic Reader Domain
Molibresib (GSK525762) is an inhibitor of BET proteins (IC50: about 35 nM).
T7361 Verucerfont NBI77860,GSK561679 CRFR
Verucerfont (NBI77860) is an antagonist of corticotropin-releasing factor receptor 1 (CRF1) .
T64366 GSK3-IN-4 GSK-3
GSK3-IN-4 is a GSK-3 inhibitor with IC50 of 0.101-1 μM of GSK-3α and GSK-3β in Calipe Assay.
T9178 (E/Z)-GSK-3β inhibitor 1 GSK-3β inhibitor 1 GSK-3
(E/Z)-GSK-3β inhibitor 1 is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy.
T6129 GSK-1070916 GSK-1070916A,GSK1070916 Apoptosis , Tie-2 , FLT , AMPK , Aurora Kinase
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
T61809 GSK-3β inhibitor 11 GSK-3
GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM. This compound demonstrates potential utility in the field of neurodegen...
T14613 BIP-135 GSK-3
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor. With IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. BIP 135 exhibits neuroprotective effect[1].
T6358 1-Azakenpaullone azakenpaullone GSK-3
1-Azakenpaullone (azakenpaullone) is a potent and selective GSK-3β inhibitor with IC50 of 18 nM, >100-fold selectivity over CDK1/cyclin B and CDK5/p25.
T2622 GSK 650394 GSK650394 SGK , Influenza Virus
GSK 650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.
T6003 GSK1904529A GSK 4529 Apoptosis , Raf , VEGFR , IGF-1R , Syk
GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .
T61360 ARN25068 GSK-3 , DYRK , Microtubule Associated , Src
ARN25068 is a potent inhibitor of GSK-3β, FYN, and DYRK1A protein kinases, exerting its activity in the sub-micromolar range. This compound effectively addresses tau hyperphosphorylation [1].
T16850 SB-265610 GSK-CXCR2 CXCR
SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...
T2310L CHIR-99021 HCl CT99021 HCl,Laduviglusib HCl GSK-3
CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivit...
T6285 GSK-690693 GSK690693 Serine Protease , Akt , PKC , AMPK , Autophagy
GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
T22341 GSK-114 Others
GSK-114, a selective inhibitor of TNNI3 Interacting Kinase (TNNI3K) with IC50 of 25 nM, shows significant bias for TNNI3K over B-Raf with IC50 of 1000 nM, exceptional broad spectrum kinase selectivity and adequate oral e...
T60485 DIF-3
DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signal...
T6458 CYC-116 VEGFR , FLT , CDK , S6 Kinase , Aurora Kinase
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 ...
T2378 RGB-286638 free base GSK-3 , MEK , JAK , CDK
RGB-286638 free base is a novel CDK inhibitor with IC50s of 1 nM/2 nM/3 nM/4 nM/5 nM for cyclin T1-CDK9/cyclin B1-CDK1/cyclin E-CDK2/cyclin D1-CDK4/cyclin E-CDK3/p35-CDK5 respectively; less potent against cyclin H-CDK7 a...
T11468 GSK-3 inhibitor 1 GSK-3
GSK-3 inhibitor 1 is a GSK-3 inhibitor.
T64143 AChE/GSK-3β-IN-1
AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-3β (IC50: 22.4 nM). AChE/GSK-3β-IN-1 is able to occupy the AT...
T27488 GSK-690 GSK 690
GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.
T76088 GSK3 Substrate, α, β subunit
GSK3 Substrate, α, β subunit, serves as a peptide substrate for Glycogen Synthase Kinase-3 (GSK-3), facilitating the measurement of GSK-3 activity [1].
T27445 GSK-1004723 GSK 1004723
GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.
T22157 TCS 2002
GSK-3β inhibitor 9 (Compound 9b) is a highly selective, orally bioavailable and potent GSK-3β inhibitor with the IC 50 of 35 nM. GSK-3β inhibitor 9 exhibits good pharmacokinetic profiles including favorable BBB penetrati...
T70965 GSK-2245035 maleate
GSK-2245035 maleate is a selective Toll-like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties.
T24969 18BIOder 18 BIOder,18-BIOder
18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.
T70724 GSK-2256098 HCl
GSK-2256098 HCl is a focal adhesion kinase-1 (FAK) inhibitor with potential antiangiogenic and antineoplastic activities.
T41232 GSK 2833503A
GSK 2833503A is a potent and selective TRPC6 and TRPC3 antagonist (IC50 = 3-16 nM and 21-100 nM, respectively). GSK 2833503A exhibits >63-fold selectivity over other ion channels, including other TRP channels, CaV1.2, hE...
T27446 GSK-1034702 GSK-1034702 HCl,GSK 1034702
GSK-1034702 is a selective M(1) receptor allosteric agonist, it may have therapeutic benefits in disorders of impaired learning including Alzheimer's disease.
T11466 GSK-2793660 Others
GSK-2793660 is an orally active and irreversible inhibitor of Cathepsin C (CTSC). GSK-2793660 is a bioactive dipeptide that can be used for the research of bronchiectasis [1] [2].
T77156 Depemokimab
Depemokimab (GSK-3511294) is a long-acting monoclonal antibody targeting IL-15, utilized in asthma research [1] [2].
T11473 GSK-5498A Others
GSK-5498A is a selective blocker of CARC (IC50, 1 μM). It inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
T80124 C-Peptide 1 (rat) GSK-3
C-Peptide 1 (rat), a β-catenin/GSK-3β activator and regulator of the Wnt/β-catenin signaling pathway, is utilized in cancer research [1].
T61804 GSK-3β inhibitor 6
GSK-3β inhibitor 6 is a highly potent inhibitor of GSK-3β, with an IC50 value of 24.4 μM. It demonstrates significant enhancement of hepatocyte glucose uptake (38%). This compound holds great potential for studying vario...
T27442 GSK 224876 GSK-224876,GSK224876
GSK 224876 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). It has activity against efavirenz-resistant strains in the treatment of treatment-naive HIV-1-infected subjects.
T69986 BMS-955176 HCl
GSK-3532795 is a second generation inhibitor of hiv-1 maturation, exhibiting a broader spectrum of antiviral effect in vitro and in clinical studies than the prototypical maturation inhibitor bevirimat
T11503 GSK 690 Hydrochloride Histone Demethylase
GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM.
T81692 Nelistotug
Nelistotug (GSK 6097608; GSK6097608) is a human IgG1κ monoclonal antibody that specifically targets CD96 [1].
T60748 ZDWX-25
ZDWX-25 is a highly potent dual inhibitor of GSK-3β and DYRK1A that possesses significant cytotoxic activities towards SH-SY5Y and HL-7702 cells. ZDWX-25 can be used for Alzheimer's disease research with an IC 50 value o...
T68855 Hymenialdisine Analogue #1
Hymenialdisine Analogue #1 is the indole derivative of Hymenialdisine, a potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micro...
T27461 GSK2336805 GSK 2336805,GSK-2336805,JNJ-56914845,GSK-805,GSK805
GSK-2336805 is a HCV NS5A inhibitor. GSK2336805 retained activity on chimeric replicons containing NS5A patient sequences from genotype 1 and patient and consensus sequences for genotypes 4 and 5 and part of genotype 6.
T75808 Phospho-Glycogen Synthase Peptide-2(substrate) TFA
Phospho-Glycogen Synthase Peptide-2 (substrate) serves as a peptide substrate for glycogen synthase kinase-3 (GSK-3) and is utilized for the affinity purification of protein-serine kinases [1].
T11961 MBM-55S GSK-3 , MAPK , Akt , Bcr-Abl , CDK , S6 Kinase , Aurora Kinase
MBM-55S is an effective inhibitor of Nek2 with an IC50 of 1 nM. MBM-55S indecus cell cycle arrest and apoptosis thereby inhibiting the proliferation of cancer cells. MBM-55S shows antitumor activities.
T79693 PIMPC GSK-3
PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits potential therapeutic effects for Alzheimer's disease [1].
T11960 MBM-55 GSK-3 , MAPK , DYRK , Akt , Chk , Bcr-Abl , CDK , S6 Kinase , Aurora Kinase
MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM. MBM-55 effectively inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis.
T80587 Alunacedase alfa HrsACE2,GSK 2586881 SARS-CoV
Alunacedase alfa (HrsACE2; GSK 2586881), a genetically modified human recombinant soluble angiotensin-converting enzyme-2 (hrsACE2), inhibits SARS-CoV-2 cell entry by competing with membrane-bound ACE2, offering potentia...
T35560 SAR502250
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM. It exhibits antidepressant-like activity and is being researched for potential...
T73196 RGB-286638
RGB-286638 is a multi-target CDK inhibitor that effectively hampers the kinase activity of a range of cyclin-CDK complexes, including cyclin T1-CDK9 (IC50 = 1 nM), cyclin B1-CDK1 (IC50 = 2 nM), cyclin E-CDK2 (IC50 = 3 nM...

Compounds

GSK-A1
T27499
Synonym:
Target: HCV Protease, PI4K
Molibresib
T1906
Synonym: GSK 525762A,GSK525762,I-BET 762
Target: Epigenetic Reader Domain
Verucerfont
T7361
Synonym: NBI77860,GSK561679
Target: CRFR
GSK3-IN-4
T64366
Synonym:
Target: GSK-3
(E/Z)-GSK-3β inhibitor 1
T9178
Synonym: GSK-3β inhibitor 1
Target: GSK-3
GSK-1070916
T6129
Synonym: GSK-1070916A,GSK1070916
Target: Apoptosis, Tie-2, FLT, AMPK, Aurora Kinase
GSK-3β inhibitor 11
T61809
Synonym:
Target: GSK-3
BIP-135
T14613
Synonym:
Target: GSK-3
1-Azakenpaullone
T6358
Synonym: azakenpaullone
Target: GSK-3
GSK 650394
T2622
Synonym: GSK650394
Target: SGK, Influenza Virus
GSK1904529A
T6003
Synonym: GSK 4529
Target: Apoptosis, Raf, VEGFR, IGF-1R, Syk
ARN25068
T61360
Synonym:
Target: GSK-3, DYRK, Microtubule Associated, Src
SB-265610
T16850
Synonym: GSK-CXCR2
Target: CXCR
CHIR-99021 HCl
T2310L
Synonym: CT99021 HCl,Laduviglusib HCl
Target: GSK-3
GSK-690693
T6285
Synonym: GSK690693
Target: Serine Protease, Akt, PKC, AMPK, Autophagy
GSK-114
T22341
Synonym:
Target: Others
DIF-3
T60485
Synonym:
Target:
CYC-116
T6458
Synonym:
Target: VEGFR, FLT, CDK, S6 Kinase, Aurora Kinase
RGB-286638 free base
T2378
Synonym:
Target: GSK-3, MEK, JAK, CDK
GSK-3 inhibitor 1
T11468
Synonym:
Target: GSK-3
AChE/GSK-3β-IN-1
T64143
Synonym:
Target:
GSK-690
T27488
Synonym: GSK 690
Target:
GSK3 Substrate, α, β subunit
T76088
Synonym:
Target:
GSK-1004723
T27445
Synonym: GSK 1004723
Target:
TCS 2002
T22157
Synonym:
Target:
GSK-2245035 maleate
T70965
Synonym:
Target:
18BIOder
T24969
Synonym: 18 BIOder,18-BIOder
Target:
GSK-2256098 HCl
T70724
Synonym:
Target:
GSK 2833503A
T41232
Synonym:
Target:
GSK-1034702
T27446
Synonym: GSK-1034702 HCl,GSK 1034702
Target:
GSK-2793660
T11466
Synonym:
Target: Others
Depemokimab
T77156
Synonym:
Target:
GSK-5498A
T11473
Synonym:
Target: Others
C-Peptide 1 (rat)
T80124
Synonym:
Target: GSK-3
GSK-3β inhibitor 6
T61804
Synonym:
Target:
GSK 224876
T27442
Synonym: GSK-224876,GSK224876
Target:
BMS-955176 HCl
T69986
Synonym:
Target:
GSK 690 Hydrochloride
T11503
Synonym:
Target: Histone Demethylase
Nelistotug
T81692
Synonym:
Target:
ZDWX-25
T60748
Synonym:
Target:
Hymenialdisine Analogue #1
T68855
Synonym:
Target:
GSK2336805
T27461
Synonym: GSK 2336805,GSK-2336805,JNJ-56914845,GSK-805,GSK805
Target:
Phospho-Glycogen Synthase Peptide-2(substrate) TFA
T75808
Synonym:
Target:
MBM-55S
T11961
Synonym:
Target: GSK-3, MAPK, Akt, Bcr-Abl, CDK, S6 Kinase, Aurora Kinase
PIMPC
T79693
Synonym:
Target: GSK-3
MBM-55
T11960
Synonym:
Target: GSK-3, MAPK, DYRK, Akt, Chk, Bcr-Abl, CDK, S6 Kinase, Aurora Kinase
Alunacedase alfa
T80587
Synonym: HrsACE2,GSK 2586881
Target: SARS-CoV
SAR502250
T35560
Synonym:
Target:
RGB-286638
T73196
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TN5171 Tricetin Apoptosis , Others , Nrf2
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...
T6S0653 Linarin Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine TNF , AChE
1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediat...
T38441 Manzamine A hydrochloride
Manzamine A hydrochloride is an orally active beta-carboline alkaloid that exhibits specific inhibitory effects on GSK-3β (IC50 = 10.2 μM) and CDK-5 (IC50 = 1.5 μM). Additionally, it targets vacuolar ATPases, leading to ...

Natural Products

Tricetin
TN5171
Synonym:
Target: Apoptosis, Others, Nrf2
Linarin
T6S0653
Synonym: Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine
Target: TNF, AChE
Manzamine A hydrochloride
T38441
Synonym:
Target:

Recombinant Proteins

Species：
Human (1418)
Mouse (231)
Cynomolgus (25)
Rat (25)
Chinese hamster (4)
RSV (4)
Phleum pratense (3)
Human (2)
Human,Cynomolgus,Rhesus (2)
Human,Cynomolgus,Rhesus macaque (2)
Expression System：
HEK293 (1312)
E. coli (204)
Baculovirus-Insect Cells (185)
CHO (14)
Yeast (10)
Human Cells (8)
Tag：
His (700)
hFc (228)
C-His-Avi (176)
Tag Free (106)
C-His (95)
His,GST (73)
C-hFc (54)
mFc (40)
His,AVI (39)
GST (38)
Cat No. Product Name Species Expression System
TMPY-04147 Frizzled 10 Protein, Human, Recombinant (His) Human HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01797 Frizzled 10 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01798 Frizzled 10 Protein, Mouse, Recombinant (His) Mouse HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-04140 Frizzled 10 Protein, Human, Recombinant (hFc) Human HEK293
Frizzled-1, also known as Fz-1, CD35 and FZD1, is a multi-pass membrane protein which belongs to theG-protein coupled receptor Fz/Smo family. Frizzled-1 / FZD1 is abundantly expressed in the cerebellum, followed by ce...
TMPY-01165 FZD1/Frizzled 1 Protein, Mouse, Recombinant (His) Mouse HEK293
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term...
TMPY-00699 CD155/PVR Protein, Human, Recombinant (hFc) Human HEK293
CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc) Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-05239 HER2/ERBB2 Protein, Human, Recombinant , Biotinylated Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01226 CD4 Protein, Mouse, Recombinant (His) Mouse HEK293
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01023 CD38 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-02031 B7-H3 Protein, Human, Recombinant (His) Human HEK293
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His) Human HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-01608 Decorin Protein, Human, Recombinant (His) Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-02019 CD59 Protein, Human, Recombinant (His) Human HEK293
CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099 CD63 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02034 Siglec-2/CD22 Protein, Human, Recombinant (His) Human HEK293
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02361 VEGFR2/KDR Protein, Human, Recombinant (His) Human HEK293
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05208 PD-L1 Protein, Human, Recombinant Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-01853 SIRP gamma Protein, Human, Recombinant (His) Human HEK293
Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunog...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His) Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-01827 CD30/TNFRSF8 Protein, Human, Recombinant (His) Human HEK293
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01283 Glypican 3/GPC3 Protein, Human, Recombinant (His) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01851 CD73 Protein, Human, Recombinant (His) Human HEK293
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-01938 CD98 Protein, Human, Recombinant (His) Human HEK293
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04698 HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) Human HEK293
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01305 OSMR Protein, Human, Recombinant (His) Human HEK293
Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His) Human HEK293
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-03958 TGF alpha Protein, Human, Recombinant Human E. coli
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-05016 HHLA2 Protein, Human, Recombinant (His) Human HEK293
B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-03383 IL-7 Protein, Human, Recombinant Human E. coli
IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progeni...
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-04069 Neurotrophin 3 Protein, Human, Recombinant Human E. coli
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate...
TMPY-01963 IL-21 Protein, Human, Recombinant Human E. coli
IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellul...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His) Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
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Frizzled 10 Protein, Human, Recombinant (His)
TMPY-04147
Species: Human
Expression System: HEK293
Frizzled 10 Protein, Mouse, Recombinant (hFc)
TMPY-01797
Species: Mouse
Expression System: HEK293
Frizzled 10 Protein, Mouse, Recombinant (His)
TMPY-01798
Species: Mouse
Expression System: HEK293
Frizzled 10 Protein, Human, Recombinant (hFc)
TMPY-04140
Species: Human
Expression System: HEK293
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
TMPY-01165
Species: Mouse
Expression System: HEK293
CD155/PVR Protein, Human, Recombinant (hFc)
TMPY-00699
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
TMPY-00664
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
TMPY-00399
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant , Biotinylated
TMPY-05239
Species: Human
Expression System: HEK293
CD4 Protein, Mouse, Recombinant (His)
TMPY-01226
Species: Mouse
Expression System: HEK293
CD38 Protein, Human, Recombinant (His)
TMPY-01023
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
B7-H3 Protein, Human, Recombinant (His)
TMPY-02031
Species: Human
Expression System: HEK293
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
TMPY-01050
Species: Human
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
TMPY-01608
Species: Human
Expression System: HEK293
CD59 Protein, Human, Recombinant (His)
TMPY-02019
Species: Human
Expression System: HEK293
CD63 Protein, Human, Recombinant (His)
TMPY-02099
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
Siglec-2/CD22 Protein, Human, Recombinant (His)
TMPY-02034
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
VEGFR2/KDR Protein, Human, Recombinant (His)
TMPY-02361
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant
TMPY-05208
Species: Human
Expression System: HEK293
SIRP gamma Protein, Human, Recombinant (His)
TMPY-01853
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
TMPY-01912
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
CD30/TNFRSF8 Protein, Human, Recombinant (His)
TMPY-01827
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His)
TMPY-01283
Species: Human
Expression System: HEK293
CD73 Protein, Human, Recombinant (His)
TMPY-01851
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
TMPY-01462
Species: Human
Expression System: HEK293
CD98 Protein, Human, Recombinant (His)
TMPY-01938
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant (His), Biotinylated
TMPY-04949
Species: Human
Expression System: HEK293
HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)
TMPY-04698
Species: Human
Expression System: HEK293
OSMR Protein, Human, Recombinant (His)
TMPY-01305
Species: Human
Expression System: HEK293
LILRB5/CD85c Protein, Human, Recombinant (His)
TMPY-04826
Species: Human
Expression System: HEK293
TGF alpha Protein, Human, Recombinant
TMPY-03958
Species: Human
Expression System: E. coli
HHLA2 Protein, Human, Recombinant (His)
TMPY-05016
Species: Human
Expression System: HEK293
IL-7 Protein, Human, Recombinant
TMPY-03383
Species: Human
Expression System: E. coli
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
Neurotrophin 3 Protein, Human, Recombinant
TMPY-04069
Species: Human
Expression System: E. coli
IL-21 Protein, Human, Recombinant
TMPY-01963
Species: Human
Expression System: E. coli
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
MXRA8 Protein, Human, Recombinant (His)
TMPK-01151
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293
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