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Search Results for " enterovirus "

Targets

23

Compounds

8

Natural Products

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6516 Golgicide A Others , Virus Protease
Golgicide A is a potent and rapidly reversible GBF1 inhibitor.
T2432 PD 169316 Virus Protease , p38 MAPK , Autophagy
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.
T1750 Pirodavir R77975 Virus Protease , Antiviral
Pirodavir (R77975) (R 77975), the prototype of broad-spectrum anti-picornavirus compounds, is a potent human rhinovirus (HRV) capsid-binding inhibitor.
T8498 EIDD-1931 Beta-d-N4-hydroxycytidine Virus Protease , HCV Protease , SARS-CoV , Topoisomerase
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity.It inhibits replication of severe acute respiratory syndrome coronavirus (SARS-CoV) in Vero 76 cells, Middle East respiratory syndr...
T4061 LY2334737 Nucleoside Antimetabolite/Analog , Others , Virus Protease
LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.
T18928 Brilliant Black BN E 151 Others , Virus Protease
Brilliant Black BN (E 151) is an azo dye and a food colorant. It is a promising antiviral agent against EV71 infection via inhibiting the interaction between EV71 and its cellular uncoating factor cyclophilin A.
T4536 Pleconaril VP 63843,Win 63843,Picovir Virus Protease , Antiviral
Pleconaril (VP 63843) is a capsid inhibitor used previously to treat enterovirus infections. Pleconaril is effective in inhibiting replication (IC50: 50 nM).
T0188 Fluticasone (propionate) CCI-187881,Fluticasone propionate Glucocorticoid Receptor , Virus Protease , Estrogen/progestogen Receptor , Phospholipase , Endogenous Metabolite
Fluticasone propionate (CCI-187881), derived from fluticasone used to remedy asthma and allergic rhinitis, is a high affinity, selective GR (glucocorticoid receptor) agonist.
T4492 Pocapavir SCH-48973,V-073 Virus Protease , Antiviral
Pocapavir (SCH-48973) is an investigational enterovirus (EV) capsid inhibitor.
T27126 DC07090 Dihydrochloride
DC07090 Dihydrochloride is a potent inhibitor of human enterovirus 71 3C protease.
T13284 Vapendavir diphosphate BTA798 diphosphate Others
Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
T24234 JX040 JX 040,JX-040
JX040 is an enterovirus replication inhibitor. JX040 has strong antiviral activity against non-polio enteroviruses and it has weak antiviral activity against polioviruses.
T36174 Methyl 3,4-Dihydroxyphenylacetate
Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0...
T13284L Vapendavir BTA798 Others
Vapendavir is a potent enteroviral capsid binder. Vapendavir has an effective antiviral activity for enterovirus 71 replication (EC50: 0.5-1.4 μM in different EV71 strains).
T61652 WIN 54954
WIN 54954 is a potent, orally active, broad-spectrum antipicornavirus agent with demonstrated efficacy against human rhinovirus, echovirus 9, and enterovirus infections [1] [2].
T38374 2-hydroxy Myristic Acid
2-hydroxy Myristic acid is a hydroxy fatty acid that has been found in bovine, human, and horse milk, cow and buffalo cheeses, sea bass filet, seal oil, human vernix caseosa, and wool wax. It inhibits cleavage between th...
T31530 Disoxaril BRN 3626820,WIN51711,WIN-51711,BRN-3626820,WIN 51711,WIN-51,711
Disoxaril (BRN 3626820, WIN 51711) is an anti-picornavirus agent that inhibits enterovirus replication by binding to a hydrophobic bag within the VP1 coat protein, thereby stabilizing virions and preventing their uncoati...
T71856 FA-613
FA-613 is a pyrimidine synthesis inhibitor which exhibits low micromolar antiviral activity against various influenza A and B virus strains, including the highly pathogenic influenza A strains H5N1 and H7N9, enterovirus ...
T61334 DMA-135 hydrochloride DMA-135 HCl Virus Protease
DMA-135 hydrochloride (DMA-135 HCl) Antivirally active compounds that target RNA and inhibit enterovirus type 71 (EV71) IRES-dependent translation and replication.DMA-135 hydrochloride can be used in the study of enterov...
T72562 Antiviral agent 23
Antiviral agent 23 is an antiviral agent to enterovirus 71 ( EV71 ) with an EC 50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research...
T60880 Viral 2C protein inhibitor 1
Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent that inhibits viral 2C protein. Viral 2C protein inhibitor 1 has relatively low cytotoxicity and high selectivity ind...
T61462 EV-A71-IN-1
EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP...
T70174 Pirlindole-d4 HCl
Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A ov...

Compounds

Golgicide A
T6516
Synonym:
Target: Others, Virus Protease
PD 169316
T2432
Synonym:
Target: Virus Protease, p38 MAPK, Autophagy
Pirodavir
T1750
Synonym: R77975
Target: Virus Protease, Antiviral
EIDD-1931
T8498
Synonym: Beta-d-N4-hydroxycytidine
Target: Virus Protease, HCV Protease, SARS-CoV, Topoisomerase
LY2334737
T4061
Synonym:
Target: Nucleoside Antimetabolite/Analog, Others, Virus Protease
Brilliant Black BN
T18928
Synonym: E 151
Target: Others, Virus Protease
Pleconaril
T4536
Synonym: VP 63843,Win 63843,Picovir
Target: Virus Protease, Antiviral
Fluticasone (propionate)
T0188
Synonym: CCI-187881,Fluticasone propionate
Target: Glucocorticoid Receptor, Virus Protease, Estrogen/progestogen Receptor, Phospholipase, Endogenous Metabolite
pocapavir
T4492
Synonym: SCH-48973,V-073
Target: Virus Protease, Antiviral
DC07090 Dihydrochloride
T27126
Synonym:
Target:
Vapendavir diphosphate
T13284
Synonym: BTA798 diphosphate
Target: Others
JX040
T24234
Synonym: JX 040,JX-040
Target:
Methyl 3,4-Dihydroxyphenylacetate
T36174
Synonym:
Target:
Vapendavir
T13284L
Synonym: BTA798
Target: Others
WIN 54954
T61652
Synonym:
Target:
2-hydroxy Myristic Acid
T38374
Synonym:
Target:
Disoxaril
T31530
Synonym: BRN 3626820,WIN51711,WIN-51711,BRN-3626820,WIN 51711,WIN-51,711
Target:
FA-613
T71856
Synonym:
Target:
DMA-135 hydrochloride
T61334
Synonym: DMA-135 HCl
Target: Virus Protease
Antiviral agent 23
T72562
Synonym:
Target:
Viral 2C protein inhibitor 1
T60880
Synonym:
Target:
EV-A71-IN-1
T61462
Synonym:
Target:
Pirlindole-d4 HCl
T70174
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T5779 MOSLOFLAVONE IL Receptor , Virus Protease , TNF , Antibacterial
MOSLOFLAVONE showed promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC50 values of 0.71 μM and 7.8 μM, respectively.
T8205 Norwogonin 5,7,8-Trihydroxyflavone Virus Protease
Norwogonin (5,7,8-Trihydroxyflavone), isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (IC50: 31.83 μg/ml).
T1670 Lanatoside C Cedilanid,Ceglunate,Isolanid ATPase , Virus Protease , Autophagy
Lanatoside C (Ceglunate) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Lanatoside C can be used orally or by the intrav...
T5S2360 Corydaline Corydalin,(+)-Corydaline P450 , Virus Protease , Opioid Receptor , AChE
1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...
T3345 Hederasaponin B Eleutheroside M,Hederacoside B Others , Virus Protease
Hederasaponin B (Hederacoside B) has antiviral activity, via inhibiting the viral VP2 protein expression and blocking viral capsid protein synthesis.
TN2111 Prunin Naringenin 7-0-glucoside Phosphatase , Anti-infection , Virus Protease
Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can...
T8180 7-Hydroxyisoflavone Others
7-Hydroxyisoflavone against Enterovirus 71 in vitro.
T21251 OSW-1 OSW1
OSW-1 is a natural broad-range inhibitor to inhibits replication of enterovirus.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02060 Human Enterovirus 71 VP0 Protein (His & GST) EV71 Baculovirus-Insect Cells
Human enterovirus 71 genome polyprotein is a member of the picornaviruses polyprotein family. It contains two peptidase C3 domains, one RdRp catalytic domain, one SF3 helicase domain. Genome polyprotein is cleaved into t...
TMPY-05044 Enterovirus D68 (EV-D68) (strain Fermon) VP1 Protein (hFc) EV-D68 Baculovirus-Insect Cells
TMPY-04797 Enterovirus D68 (EV-D68) (strain Fermon) VP4 Protein (hFc) EV-D68 Baculovirus-Insect Cells
TMPY-05768 LIMPII/SR-B2 Protein, Human, Recombinant (hFc) Human HEK293
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all ...
TMPY-01024 LIMPII/SR-B2 Protein, Human, Recombinant (His & hFc) Human HEK293
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all ...
TMPY-01434 LIMPII/SR-B2 Protein, Mouse, Recombinant (His) Mouse HEK293
Lysosomal Integral Membrane Protein II (LIMPII), also known as SCARB2, LPG85, and CD36L2, is a type I II multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all ...
TMPJ-00298 CD36 Protein, Human, Recombinant (aa 27-432, His) Human Human Cells
Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlie...
TMPJ-00299 LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Lysosome membrane protein II (LIMPII),also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far e...
TMPH-02555 C1QL1 Protein, Mouse, Recombinant (His) Mouse Yeast
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regul...
TargetMol