dasa — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6816	DASA-58		PKM
	DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.		PKM
T23992	Diazobenzenesulfonic acid	Diazobenzenesulphonate,diazobenzene sulfonic acid,DASA,Diazobenzene sulfonate,Diazobenzenesulfonate
	Diazobenzenesulfonic acid is a whiter or reddish crystalline acid derivative of sulfanilic acid. It is a desensitizer (inhibitor) of allosteric effect for myosin ATPase 13.
T18595	Dasatinib carbaldehyde	PROTAC ABL binding moiety 4,BMS-354825 carbaldehyde	Others , Ligands for Target Protein for PROTAC
	Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].		Others , Ligands for Target Protein for PROTAC
T27122	Dasantafil	SCH446132,SCH-446132,SCH 446132	PDE
	Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.		PDE
T1448L	Dasatinib monohydrate	BMS-354825 Monohydrate	Apoptosis , Bcr-Abl , Src , c-Kit , Ephrin Receptor , Autophagy
	Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activit...
T3489	Dasabuvir	ABT-333	HCV Protease
	Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase, with potential activity against HCV. Upon administration and after intra...		HCV Protease
T37600	Dasatinib N-oxide		Others
	Dasatinib N-oxide is a major metabolite of the Abl and Src kinase inhibitor dasatinib.It is also a potential impurity in commercial preparations of dasatinib[1][2].		Others
T18750	N-Deshydroxyethyl Dasatinib	N-Deshydroxyethyl BMS-354825	Others , IAP , Drug Metabolite
	N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER.N-Deshydroxyethyl Dasatinib i...		Others , IAP , Drug Metabolite
T6254	Idasanutlin	RG7388,Ro 5503781	Mdm2 , E1/E2/E3 Enzyme
	Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).		Mdm2 , E1/E2/E3 Enzyme
T22303	Dasatinib hydrochloride	BMS-354825 HCl	Bcr-Abl , Src , c-Kit
	Dasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bc...		Bcr-Abl , Src , c-Kit
T15198	Edasalonexent	CAT-1004	NF-κB
	Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor for the improvement of Duchenne muscular dystrophy.		NF-κB
T1448	Dasatinib	BMS-354825	Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
	Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...		Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
T10962	Dasatinib-d8	BMS-354825 D8	Others
	Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.		Others
T63593	Dasabuvir sodium
	Dasabuvir (ABT-333) sodium is a non-nucleoside hepatitis C virus (HCV) polymerase inhibitor. sodium exhibits inhibition of the RNA-dependent RNA polymerase (RNA polymerase) encoded by the HCV NS5B gene. sodium inhibits D...
T37645	Dasatinib metabolite M6
	Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].