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Results for "

DASA

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    17
    TargetMol | Inhibitors_Agonists
  • PROTAC Products
    2
    TargetMol | PROTAC
  • Isotope Products
    1
    TargetMol | Isotope_Products
DASA-58
T68161203494-49-8
DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.
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TargetMol | Inhibitor Sale
Edasalonexent
CAT-1004
T151981204317-86-1In house
Edasalonexent (CAT-1004) is an orally available NF-κB inhibitor designed to improve Duchenne muscular dystrophy.
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6-8 weeks
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Dasantafil
SCH-446132, SCH446132, SCH 446132
T27122569351-91-3In house
Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.
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6-8weeks
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TargetMol | Inhibitor Sale
Dasatinib
BMS-354825
T1448302962-49-8
Dasatinib (BMS-354825) is an orally active, ATP-competitive tyrosine kinase inhibitor that targets Src and Bcr-Abl (Ki=16 30 pM), with antitumor activity, used in the treatment of leukemia and lymphoma.
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Dasatinib monohydrate
BMS-354825 Monohydrate
T1448L863127-77-9
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
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Dasabuvir
ABT-333
T34891132935-63-7
Dasabuvir (ABT-333) is a non-nucleoside inhibitor of the hepatitis C virus (HCV) non-structural protein 5B (NS5B), an RNA-dependent RNA polymerase. Upon administration and intracellular uptake, dasabuvir binds HCV NS5B polymerase, blocking viral RNA synthesis and replication. The HCV NS5B protein is essential for the replication of the HCV RNA genome.
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Idasanutlin
RG7388, Ro 5503781
T62541229705-06-9
Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).
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Dasatinib carbaldehyde
PROTAC ABL binding moiety 4, BMS-354825 carbaldehyde
T185952112837-79-1
Dasatinib carbaldehyde (PROTAC ABL binding moiety 4) is based on Dasatinib which is an ABL inhibitor, binds to the IAP ligand via a linker, and forms SNIPER [1].
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TargetMol | Inhibitor Sale
N-Deshydroxyethyl Dasatinib
N-Deshydroxyethyl BMS-354825
T18750910297-51-7
N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) is a metabolite of Dasatinib, a dasatinib-based molecule that degrades ABL by binding to the IAP ligand via a linker to form SNIPER. N-Deshydroxyethyl Dasatinib is used in the study of cancer and immune diseases.
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TargetMol | Inhibitor Sale
Dasatinib N-oxide
T37600910297-52-8
Dasatinib N-oxide is a minor metabolite of Dasatinib.Dasatinib is an orally potent inhibitor of Src Bcr-Abl.
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TargetMol | Inhibitor Sale
Dasatinib-d8
BMS-354825 D8
T109621132093-70-9
Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.
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7-10 days
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Dasatinib hydrochloride
BMS-354825 HCl
T22303854001-07-3
Dasatinib hydrochloride (BMS-354825 HCl) (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride hydrochloride inhibits Bcr-Abl and Src with IC50s of <1.0 nM and 0.5 nM, respectively. Dasatinib hydrochloride hydrochloride also induces Apoptosis and Autophagy.
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6-8 weeks
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Dasatinib metabolite M6
T37645910297-53-9
Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative derivative of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].
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7-10 days
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Dasabuvir sodium
T635931132940-11-4
Dasabuvir (ABT-333) sodium is a non-nucleoside hepatitis C virus (HCV) polymerase inhibitor that exhibits inhibition of the RNA-dependent RNA polymerase (RNA polymerase) encoded by the HCV NS5B gene. Dasabuvir sodium inhibited genotype 1a (strain H77) replicon (EC50: 7.7 nM) and 1b (strain Con1) replicon (EC50: 1.8 nM).
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1-2 weeks
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Dasatinib analog-1
T846871174416-41-1
Dasatinib analog-1 (compound 5826) demonstrates inhibition of CYP3A4 activity, presenting a K_i value of 5.4 μM, and effectively prevents the formation of glutathione adducts [1].
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8-10 weeks
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Hydroxymethyl dasatinib
T86695910297-58-4
Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib, demonstrates potent activity with an IC50 value of 46.7 nM in K562 CML cells [1].
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10-14 weeks
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Diazobenzenesulfonic acid
Diazobenzenesulphonate,diazobenzene sulfonic acid,DASA,Diazobenzene sulfonate,Diazobenzenesulfonate
T239922154-66-7
Diazobenzenesulfonic acid is a whiter or reddish crystalline acid derivative of sulfanilic acid. It is a desensitizer (inhibitor) of allosteric effect for myosin ATPase 13.
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6-8 weeks
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