dac — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T25284	DAC-2-25	DAC 225,DAC-225,DAC 2 25	Others
	DAC-2-25 is a Hydra head regeneration modulator. It acts by inducing a homeotic transformation in Hydra.		Others
T23948	Dac 5945
	DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.
T19914	Chlorothalonil	DAC 2787,Daconil,Daconil M	Antifungal
	Chlorothalonil (DAC 2787) is a broad-spectrum fungicide with high efficiency and low toxicity. Chlorothalonil is widely used to control various pests such as fruit trees and vegetable leaves. Chlorothalonil also has good...		Antifungal
T23975	Deacylcortivazol	UNII-3JO09QT49F,DAC,NSC 325316
	Deacylcortivazol (DAC) is a potent glucocorticoid. When incubated with glucocorticoid-resistant mutants derived from the glucocorticoid-sensitive human leukemic cell line CEM-C7, DAC caused significant growth inhibition....
T15047	Dacisteine	N,S-Diacetyl-L-cysteine	Others
	Dacisteine (N,S-Diacetyl-L-cysteine) is an inhibitor of New Delhi metallo-beta-lactamase-1 (NDM-1, IC50 = 1000 μM).		Others
TQ0063	Zoliflodacin	ETX0914,AZD0914	DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial
	Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aur...
T2235	Dactolisib	BEZ235,NVP-BEZ235	ATM/ATR , PI3K , mTOR , Autophagy
	Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).		ATM/ATR , PI3K , mTOR , Autophagy
T72077	Imidacloprid-urea
	Imidacloprid-urea is a secondary metabolite of imidacloprid. Imidacloprid is a potent and widely used neonicotinoid with inhibitory effects on pests of cereals, vegetables, tea and cotton. imidacloprid-urea can occupy or...
T67152	Dacomitinib Intermediate 2	N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine	Others
	Dacomitinib Intermediate 2 (N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine) has anticancer activity and can be used to study lung cancer.		Others
T77334	HDAC-IN-57		Apoptosis , HDAC
	HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with ...		Apoptosis , HDAC
T8508	HDAC-IN-3	GSK3117391A	HDAC
	HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.		HDAC
T67878	HDAC-IN-52		HDAC
	HDAC-IN-52 is a pyridine-containing HDAC inhibitor that inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 0.189, 0.227, 0.440 and 0.446 μM, respectively. HDAC-IN-52 can be used in cancer research.		HDAC
T7503	Upadacitinib	ABT-494	JAK
	Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.		JAK
T26278	Tildacerfont		CRFR
	Tildacerfont is an antagonist of CRF1 and reduces the levels of adrenocorticotropic hormone and adrenal androgen. Tildacerfont can be used in studies about congenital adrenal hyperplasia.		CRFR
T2320	Indacaterol		Adrenergic Receptor
	Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.		Adrenergic Receptor
T73689	Daclizumab	Ro 24-7375,Zenapax	IL Receptor
	Daclizumab (Zenapax) is a humanized monoclonal antibody that specifically inhibits the alpha subunit of IL-2R-HA. Daclizumab (Zenapax) can inhibit the binding of IL-2 and IL-2R-HA through specific binding to CD25. Dacliz...		IL Receptor
T1786	Daclatasvir dihydrochloride	BMS-790052 dihydrochloride	HCV Protease
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to ...		HCV Protease
T6229	Daclatasvir	Daklinza,EBP 883,BMS-790052	HCV Protease
	Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.		HCV Protease
T14552	Dactolisib Tosylate	BEZ235 Tosylate,NVP-BEZ 235 Tosylate	PI3K , mTOR
	Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor that targets PI3K and mTOR. dactolisib Tosylate exhibits IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. dactolisib Tosylate inhibi...		PI3K , mTOR
T1239	Indacaterol maleate	QAB149	Adrenergic Receptor
	Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.		Adrenergic Receptor