Search Result

Search Results for " curcumin "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T10901	Curcumin-d6	Turmeric yellow D6,Natural Yellow 3 D6,Curcumin D6,Diferuloylmethane D6	Others
	Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxi...		Others
T8055	TFEB activator 1	(1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612	Others , Autophagy
	TFEB activator 1 (Curcumin analog compound C1) is an activator of transcription factor EB (TFEB) with promise for the prevention or treatment of Alzheimer's disease.		Others , Autophagy
T74279	Curcumin monoglucuronide
	Curcumin monoglucuronide, a glucuronic acid conjugate and in vivo metabolite of curcumin, is utilized in the study of curcumin's metabolism and the exploration of its pharmaceutical development. It holds promise for canc...
T74716	Curcumin 5-8
	Curcumin 5-8 (CUR5-8), a naturally active analog of curcumin (CUR), exhibits potent oral activity. It effectively inhibits lipid droplet formation, enhances autophagy, and reduces apoptosis. Additionally, Curcumin 5-8 ha...
T78519	Curcumin-β-D-glucuronide		Others
	Curcumin-β-D-glucuronide, a principal metabolite detected in hepatic tissue and portal blood following oral consumption of Curcumin, is utilized in colon cancer research [1] [2].		Others
T83881	4-(3,4-Difluorobenzo)curcumin	CDF
	4-(3,4-Difluorobenzo)curcumin (CDF) is a semisynthetic coumarin noted for its antiparasitic and anticancer properties. It effectively reduces the population of Vero cells infected by T. gondii promastigotes and amastigot...
T40423	L48H37
	L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T19853	Dimethoxycurcumin	Veratrylcurcuminoid	Others
	Dimethoxycurcumin (Veratrylcurcuminoid) is an analog of curcumin with more metabolical stability. Dimethoxycurcumin induces epigenetic changes in leukemia cells and the expression of promoter methylated genes.		Others
T13135	Tetrahydrocurcumin D6	HZIV 81-2 D6	Others
	Tetrahydrocurcumin D6 is a deuterium labeled Tetrahydrocurcumin. Tetrahydrocurcumin displays inhibitory activity for CYP2C9 and CYP3A4.		Others
T6537	HO-3867	HO3867	Apoptosis , STAT
	HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.		Apoptosis , STAT
T7374	2-HBA		Caspase , NADPH
	2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.		Caspase , NADPH
T1993	J-147	J147	Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
	J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T50107	Ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate		Others
	ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate is a synthetic compound belonging to the curcumin family. It is involved in the regulation of immune response and inflammation through ...		Others
T20303	Dibenzalacetone	AI3-00896,AI3 00896,AI300896
	Dibenzylideneacetone is a synthetic curcumin analog. It leads to apoptotic cell death in Leishmania donovani.
T71208	GO-Y078
	GO-Y078 is an antiangiogenic curcumin analog which inhibits actin stress fiber formation, thereby resulting in mobility inhibition.
T38307	Tetranor-PGJM
	Tetranor-PGJM is a metabolite of prostaglandin D2 and is associated with the anti-inflammatory effects of curcumin.
T81177	Ser@TPP@CUR
	Ser nM TPP nM CUR, a derivative of Curcumin, notably mitigates damage in renal tubular epithelial cells and enhances renal function in mice with acute kidney injury (AKI). This compound holds potential for AKI research a...
T37148	TML-6
	TML-6, an oral curcumin derivative, demonstrates inhibitory effects on the synthesis of β-amyloid precursor protein and β-amyloid (Aβ). Additionally, TML-6 exhibits upregulation of Apo E, suppression of NF-κB and mTOR, a...
T61181	Pentagamavunon-1
	Pentagamavunon-1 (PGV-1) is an oral Curcumin analog that effectively induces apoptosis through multiple molecular mechanisms. It primarily targets and inhibits key angiogenic factors, including cyclooxygenase-2 (COX-2) a...
T78158	MitoCur-1		Others
	MitoCur-1, a curcumin analogue, acts as an inhibitor of mitochondrial antioxidative enzyme thioredoxin reductase 2 (TrxR2), possessing electrophilic characteristics with mitochondrial-targeting capabilities. This compoun...		Others
T36015	PDMP (hydrochloride)
	PDMP is a ceramide analog first prepared in a search for inhibitors of glucosylceramide synthase. PDMP has two adjacent chiral centers (C1 and C2) allowing for the formation of four possible isomers. PDMP contains all fo...

Compounds

Curcumin-d6

T10901

Synonym: Turmeric yellow D6,Natural Yellow 3 D6,Curcumin D6,Diferuloylmethane D6

Target: Others

TFEB activator 1

T8055

Synonym: (1E,4E)-1,5-Bis(2-Methoxyphenyl)penta-1,,Curcumin analog compound C1,Curcumin analog C1,RPN77612

Target: Others, Autophagy

Curcumin monoglucuronide

Curcumin-β-D-glucuronide

T78519

Synonym:

Target: Others

4-(3,4-Difluorobenzo)curcumin

Synonym: Veratrylcurcuminoid

Target: Others

Tetrahydrocurcumin D6

T13135

Synonym: HZIV 81-2 D6

Target: Apoptosis, STAT

2-HBA

T7374

Synonym:

Target: Caspase, NADPH

J-147

T1993

Synonym: J147

Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase

ethyl 2-[3,5-bis(trifluoromethyl)phenyl]-3-oxo-2,3-dihydro-1H-pyrazole-4-carboxylate

Synonym: AI3-00896,AI3 00896,AI300896

Cat No.	Product Name	Synonyms	Targets
T1516	Curcumin	Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow	Mitophagy , Epigenetic Reader Domain , Ferroptosis , Influenza Virus , Nrf2 , Histone Acetyltransferase , HDAC , Autophagy
	Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, ant...
T6S1688	(1E,6E)-Bis(demethoxy)curcumin	Curcumin III,Didemethoxycurcumin,BDMC	Apoptosis , Others , Autophagy
	(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.		Apoptosis , Others , Autophagy
TL0007	Bisdemethoxycurcumin	Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain , Wnt/beta-catenin
	Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...		Epigenetic Reader Domain , Wnt/beta-catenin
T6S1683	Demethoxycurcumin	Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin	Apoptosis , Antioxidant , Antibacterial , Autophagy
	1. Demethoxycurcumin (Desmethoxycurcumin) has antioxidant activity. 2. Demethoxycurcumin has anti-inflammatory activity. 3. Demethoxycurcumin has anti-proliferative activity. 4. Demethoxycurcumin has anti-acanthamoebic e...		Apoptosis , Antioxidant , Antibacterial , Autophagy
T3735	Tetrahydrocurcumin	Sabiwhite,Tetrahydrodiferuloylmethane,HZIV 81-2,Tetrahydro Curcumin	P450 , Endogenous Metabolite , Autophagy
	Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.		P450 , Endogenous Metabolite , Autophagy
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T3S1701	Dihydrocurcumin		PPAR , Fatty Acid Synthase
	Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress response. Dihydrocurcumin can regulate the mRNA and protein expression levels of SREBP-1C, PNPLA3 and PPARα, incr...		PPAR , Fatty Acid Synthase
TQ0214	Dimethylcurcumin	ASC-J9,GO-Y025	Androgen Receptor
	Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.		Androgen Receptor
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T3S1692	Octahydrocurcumin		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
	Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahy...		Anti-infection , NF-κB , Reactive Oxygen Species , ROS
T4803	(E/Z)-Demethoxycurcumin		Others
	Demethoxycurcumin is found in Curcuma zedoaria and Etlingera elatior. It has a role as a metabolite, an antineoplastic agent and an anti-inflammatory agent.		Others
T11034	Di-O-methyldemethoxycurcumin		IL Receptor
	Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.		IL Receptor
TN3741	Cyclocurcumin		TNF , ROS
	Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It m...		TNF , ROS
TN5760	3''-Demethylhexahydrocurcumin	5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)heptan-3-one
	3''-Demethylhexahydrocurcumin is a natural product for research related to life sciences. The catalog number is TN5760 and the CAS number is 881008-71-5.
TN5656	5"-Methoxyhexahydrocurcumin
	5"-Methoxyhexahydrocurcumin is a natural product for research related to life sciences. The catalog number is TN5656 and the CAS number is 138870-96-9.
T82640	Cyclobisdemethoxycurcumin
	Cyclobisdemethoxycurcumin exhibits antioxidant properties, demonstrated by its half maximal inhibitory concentrations (IC50s) of approximately 250 μM in the DPPH radical scavenging assay and 15-20 μM in the 2-DR oxidatio...
T38499	κ-Carrageenan
	κ-Carrageenan, a natural polymer found predominantly in red seaweeds, can serve as an effective drug carrier for delivering curcumin to cancer cells and inducing apoptosis. Additionally, κ-Carrageenan holds promise as a ...

Natural Products

Curcumin

T1516

Synonym: Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow

Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy

(1E,6E)-Bis(demethoxy)curcumin

T6S1688

Synonym: Curcumin III,Didemethoxycurcumin,BDMC

Target: Apoptosis, Others, Autophagy

Bisdemethoxycurcumin

TL0007

Synonym: Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

Demethoxycurcumin

T6S1683

Synonym: Curcumin II,Desmethoxycurcumin,Monodemethoxycurcumin

Target: Apoptosis, Antioxidant, Antibacterial, Autophagy

Tetrahydrocurcumin

T3735

Synonym: Sabiwhite,Tetrahydrodiferuloylmethane,HZIV 81-2,Tetrahydro Curcumin

Target: P450, Endogenous Metabolite, Autophagy

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Dihydrocurcumin

T3S1701

Synonym:

Target: PPAR, Fatty Acid Synthase

Dimethylcurcumin

TQ0214

Synonym: ASC-J9,GO-Y025

Target: Androgen Receptor

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Octahydrocurcumin

T3S1692

Synonym:

Target: Anti-infection, NF-κB, Reactive Oxygen Species, ROS

(E/Z)-Demethoxycurcumin

T4803

Synonym:

Target: Others

Di-O-methyldemethoxycurcumin

3''-Demethylhexahydrocurcumin

TN5760

Synonym: 5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-7-(3,4-dihydroxyphenyl)heptan-3-one

Target:

5"-Methoxyhexahydrocurcumin

TN5656

Synonym:

Target:

Cyclobisdemethoxycurcumin

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00090	UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)	Arabidopsis thaliana	E. coli
	Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...
TMPH-00091	UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)	Arabidopsis thaliana	Yeast
	Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...

UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His)

TMPH-00090

Species: Arabidopsis thaliana

Expression System: E. coli

UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His)

TMPH-00091

Species: Arabidopsis thaliana

Expression System: Yeast

Cat No.	Product Name
L6100	Polyphenolic Natural Product Library	640 compounds
	A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);
L6750	PBCRBS Traditional Chinese Medicine Compound Library	588 compounds
	A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.

Libraries

Polyphenolic Natural Product Library

L6100

Compounds: 640

PBCRBS Traditional Chinese Medicine Compound Library

L6750

Compounds: 588