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Cat No. | Product Name | Synonyms | Targets |
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T14860 | CaMKII-IN-1 | CaMK , Autophagy | |
CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, p38a, MLCK, Akt1, and PKC. | |||
TQ0137 | A-484954 | A 484954 | CaMK , Parasite , Autophagy |
A-484954 (A 484954) is a highly specific eukaryotic elongation factor-2 (eEF2, IC50: 280 nM) inhibitor. | |||
T2697 | KN-93 | CaMK , Autophagy | |
KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. | |||
TP2310 | Autocamtide-2-related inhibitory peptide | CaMK , Autophagy | |
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | |||
T6605 | NH125 | CaMK , Virus Protease , PKA , Antibacterial , PKC , Autophagy , Antifungal | |
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor. | |||
T3546 | STO-609 | STO 609 | CaMK , AMPK , Autophagy |
STO-609 is a specific and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK) for recombinant CaM-KKα/KKβ (Ki: 80/15 ng/mL). | |||
T2694 | KN-62 | CaMK , P2X Receptor , Autophagy | |
KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM. | |||
T10667 | Calmidazolium chloride | R 24571 | CaMK , Autophagy |
Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist (Kd = 3 nM), antagonizing CaM-dependent phosphodiesterase(IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase(IC50 ... | |||
T14069 | A-3 hydrochloride | CaMK , Casein Kinase , PKA , PKC | |
A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectiv... | |||
T8389 | Trifluoperazine | trifluoroperazine | CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy |
Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia. | |||
T4185 | Lavendustin C | HDBA,NSC 666251 | CaMK , EGFR , Tyrosinase , Src |
lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase. | |||
T1222 | Trifluoperazine dihydrochloride | Trifluoperazine 2HCl,SKF5019,Urinox | CaMK , Dopamine Receptor , Influenza Virus , Adrenergic Receptor , P-gp , Autophagy |
Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. | |||
T2159 | CaMKP Inhibitor | CaMK | |
CaMKP Inhibitor can inhibit CaMKP. | |||
T79718 | CaMKIIα-PHOTAC | CaMK | |
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα). This molecule facilitates the ubiquitination and subsequent proteasome-medi... | |||
T60515 | CaMKIIα-IN-1 | ||
CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub. CaMKIIα-IN-1 shows good metabolic stability [1]. | |||
T2606 | KN-93 Phosphate | CaMK | |
KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II with K i of 370 nM. KN-93 phosphate inhibits serum-induced fibroblast cell growth in a comparable dose-dependent fashion to it... | |||
T3935 | 1-Naphthyl PP1 | 1-NA-PP 1 | Src |
1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively) | |||
T7371 | 1-Naphthyl PP1 hydrochloride | 1-NA-PP 1 hydrochloride | Src |
1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-Src | |||
T4444 | A-674563 HCl (552325-73-2(free base)) | ERK , Akt , PKA , CDK , PKC | |
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for A... | |||
TP1216 | CaM kinase II inhibitor TFA salt | Autocamtide-2-related inhibitory peptide (TFA) | CaMK |
CaM kinase II inhibitor TFA salt (Autocamtide-2-related inhibitory peptide (TFA)) is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. | |||
TP1271L | Calmodulin-Dependent Protein Kinase II 290-309 acetate | Calmodulin-Dependent Protein Kinase II 290-309 acetate (115044-69-4 Free base) | CaMK |
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM). | |||
T4530 | KN-92 phosphate | KN92-H3PO4 | CaMK |
KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). | |||
T13384L | Y-33075 dihydrochloride | CaMK , ROCK , PKC | |
Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM). | |||
TP1829 | Autocamtide 2, amide | ||
Autocamtide 2, amide is a substrate (100 μM final concentration) for CaMK family assays.Autocamtide-2 Peptide is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), a member ... | |||
T76408 | Autocamtide-3 | ||
Autocamtide-3, a selective substrate for CaMKII (Ca2+/calmodulin-dependent kinase II) (CaMK), comprises a 13-amino-acid peptide featuring Thr287 [1]. | |||
T75959 | Calmodulin-Dependent Protein Kinase II(290-309) acetate | ||
Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent antagonist of CaMK, exhibiting an IC50 of 52 nM for the inhibition of Ca2+/calmodulin-dependent protein kinase II [1]. | |||
TP1217 | Autocamtide 2 | Autocamtide II | |
Autocamtide-2 is a highly selective peptide substrate for calcium/calmodulin-dependent protein kinase II (CaMKII), which belongs to the CAMK Ser/Thr protein kinase family. | |||
T73247 | PIM1-IN-4 | Pim | |
PIM1-IN-4 (Compound 8) is a potent PIM1 inhibitor with significant inhibitory activity against five additional enzymes: SGK-1, PKA, CaMK-1, GSK3β, and MSK1, rendering it a potentially useful agent for cancer research [1]... | |||
TP1271 | Calmodulin-Dependent Protein Kinase II (290-309) | Calmodulin-Dependent Protein Kinase II(290-309) | |
Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II. | |||
T76488 | Calmodulin Dependent Protein Kinase Substrate | ||
Calmodulin Dependent Protein Kinase Substrate is a synthetic peptide that serves as a substrate for protein kinases and requires calcium ions (Ca 2+) and calmodulin (CaM) for activation. It specifically interacts with ca... | |||
TQ0319 | Ripasudil | K-115,Ripasudil hydrochloride dihydrate | ROCK |
Ripasudil (Ripasudil hydrochloride dihydrate) (K-115) hydrochloride dihydrate is a specific ROCK inhibitor (IC50s: 51/19 nM for ROCK1/ROCK2). | |||
T76487 | Calmodulin Dependent Protein Kinase Substrate Analog | ||
Calmodulin-Dependent Protein Kinase Substrate Analog, a synthetic peptide substrate, is activated by Ca2+ and calmodulin (CaM). It serves as a substrate for protein kinases, leveraging a dependency on Ca2+ and CaM for it... | |||
T16752 | Rimacalib | SMP 114 | CaMK |
Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ). | |||
T35328 | H-1152 dihydrochloride | H-1152 2HCl,H-1152 dihydrochloride | ROCK |
H-1152 dihydrochloride (H-1152 2HCl) is a specific inhibitor of Rho-associated protein kinase (ROCK) with an IC50 of 12 nM and a Ki of 1.6 nM. H-1152 dihydrochloride inhibits PKA, PKC, PKG, Aurora A and CaMKII with IC50 ... | |||
T13384 | Y-33075 | Y 39983 | PKC |
Y-33075 is a selective inhibitor of ROCK derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM. | |||
T35459 | Glycyl H-1152 hydrochloride | ||
Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and prol... | |||
T7492 | Ripasudil free base | K-115 (free base) | ROCK , Antibacterial |
Ripasudil free base (K-115 (free base)) is a selective and potent ROCK inhibitor, is a novel and potent antiglaucoma agent. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15636 | K-252a | Antibiotic K 252a,Antibiotic SF 2370,SF2370 | Others |
K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphoryla... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04543 | CAMKIV Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme i... | |||
TMPH-01027 | CAMK2D Protein, Human, Recombinant (His) | Human | E. coli |
Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in C... | |||
TMPY-04408 | CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro... | |||
TMPJ-00240 | CAMK1 Protein, Human, Recombinant (His) | Human | Human Cells |
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed.... | |||
TMPY-04573 | CAMKIV Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme i... | |||
TMPY-04759 | CAMKIV Protein, Mouse, Recombinant | Mouse | Baculovirus-Insect Cells |
Ca2+/ calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca2+/calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme i... | |||
TMPY-04423 | CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular r... | |||
TMPY-04566 | CAMKV Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
CaM kinase-like vesicle-associated protein, also known as CAMKV, is a peripheral membrane protein and Cytoplasmic vesicle membrane protein which belongs to theprotein kinase superfamily and CAMK Ser/Thr protein kinase... | |||
TMPY-04415 | CAMKI Protein, Human, Recombinant | Human | E. coli |
Calcium/calmodulin-dependent protein kinase orCaM kinases are serine/threonine-specific protein kinasesthat are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. ... | |||
TMPY-04381 | CAMK1D Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Calcium/calmodulin-dependent protein kinase orCaM kinases are serine/threonine-specific protein kinasesthat are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. ... | |||
TMPY-04373 | CAMKII alpha/CAMK2A Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Ca2+/calmodulin-dependent protein kinase2A (CAMK2A) belongs to the serine/threonine protein kinase family and, together with other 28 different isoforms, belongs to the Ca2+/ calmodulin-dependent protein kinase subfamily... | |||
TMPH-01026 | CAMK2N1 Protein, Human, Recombinant (His & Trx) | Human | E. coli |
Potent and specific inhibitor of CaM-kinase II (CAMK2). | |||
TMPY-04406 | Protein Kinase D2/PRKD2 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
Serine/threonine-protein kinase D2, also known as PRKD2 and PKD2, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and PKD subfamily. PRKD2 / PKD2 is ... | |||
TMPY-04557 | PHKG1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Phosphorylase b kinase gamma catalytic chain, skeletal muscle isoform, also known as Phosphorylase kinase subunit gamma-1 and PHKG1, is a member of the protein kinase superfamily and CAMK Ser/Thr protein kinase family. P... | |||
TMPY-04471 | APEG1 Protein, Human, Recombinant (His) | Human | E. coli |
Striated muscle preferentially expressed protein kinase, also known as aortic preferentially expressed protein 1, APEG-1, SPEG and KIAA1297, is a protein that belongs to the protein kinase superfamily and CAMK Ser/Thr pr... | |||
TMPY-04425 | PRAK/MAPKAPK5 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
MAPKAPK5 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family. MAPKAPK5 has significant sequence homology to mitogen-activated protein kinase (MAPK)-activated... | |||
TMPY-04417 | DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST) | Human | Baculovirus-Insect Cells |
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK... | |||
TMPY-04368 | Chk1 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
CHK1 / CHEK1 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily. It is a member of checkpoint kinases (Chks). Chks Checkpoint kinases (Chks)... | |||
TMPY-04385 | ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP ... | |||
TMPY-04433 | Chk1 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
CHK1 / CHEK1 contains 1 protein kinase domain and belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, NIM1 subfamily. It is a member of checkpoint kinases (Chks). Chks Checkpoint kinases (Chks)... | |||
TMPY-04461 | TRIB3 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Tribbles homolog 3, also known as Neuronal cell death-inducible putative kinase, p65-interacting inhibitor of NF-kappa-B, SINK and TRIB3, is a Nucleus protein that belongs to the protein kinase superfamily and CAMK Ser/T... | |||
TMPY-04456 | PKC nu Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Serine/threonine-protein kinase D3, also known as Protein kinase C nu type, Protein kinase EPK2, PRKD3, EPK2 and PRKCN, is a cytoplasm and membrane protein that belongs to the protein kinase superfamily, CAMK Ser/Thr pro... |