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Search Results for " crispr/cas9 "

Targets

13

Compounds

1

Natural Products

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T6972 RS-1 DNA/RNA Synthesis
RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.
T6872 L755507 Adrenergic Receptor , CRISPR/Cas9
L755507 is an effective, selective agonist of β3-AR(IC50=35 nM).
T2802 Nocodazole R17934,Oncodazole Apoptosis , Microtubule Associated , Bcr-Abl , Autophagy , CRISPR/Cas9
Nocodazole (Oncodazole) is a reversible inhibitor of microtubule polymerization and an inhibitor of Bcr-Abl. Nocodazole has antitumor activity, blocks the cell cycle and induces apoptosis.
T6276 KU-57788 NU7441 DNA-PK , CRISPR/Cas9
NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).
T1724 SCR7 pyrazine SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T1416 Zidovudine Azidothymidine,NSC 602670,ZDV,AZT HIV Protease , Reverse Transcriptase , Telomerase , CRISPR/Cas9
Zidovudine (ZDV) is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This age...
T4420 4-Hydroxytamoxifen ICI 79280,(Z)-4-hydroxy Tamoxifen,trans-4-Hydroxytamoxifen Estrogen Receptor/ERR , Estrogen/progestogen Receptor
4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer rese...
T3340 SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
T74639 TT3
TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery [1] [2] .
T60520 Cas9-IN-3
Cas9-IN-3 is a potent inhibitor of Cas9 with IC50 of 28 μM. CRISPR/Cas systems have revolutionized gene editing in several species [1].
T81513 Peptide A5K acetate
Peptide A5K acetate, an INF7-TAT derivative, facilitates CRISPR RNP delivery to T cells and effectively enhances Cas9 RNP transport to natural killer (NK) cells [1].
T39810 CEM114
CEM114 is a potent chemical compound known as a chemical epigenetic modifier (CEM). It functions by employing CRISPR-Cas9 systems to harness endogenous chromatin machinery, thereby exerting its epigenetic modifying effec...
T74449 N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide
N1,N3,N5-Tris(4-dodecylhexadecyl)benzene-1,3,5-tricarboxamide is an analogue of TT3 . TT3 is an ionizable lipid-like materials for mRNA and CRISPR/Cas9 delivery [1] [2] .
Cat No. Product Name Synonyms Targets
T6062 Brefeldin A BFA,Ascotoxin,Cyanein,Decumbin ATPase , Mitophagy , Antibiotic , Autophagy , HSV , CRISPR/Cas9
Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM). Brefeldin A can induce tumor cell differentiation and apoptosis, and also possesses autophagy inhibitory activ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05346 CRISPR-Cas9 Protein, Streptococcus pyogenes, Recombinant (His) Streptococcus pyogenes Baculovirus-Insect Cells
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