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Cat No. | Product Name | Synonyms | Targets |
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T10708 | CCR1 antagonist 6 | CCR | |
CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM). | |||
T15253 | CCX354 | CCR1 antagonist 1,CCX-354,CCX 354 | CCR |
CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis. | |||
T30258 | AZD-4818 | CCR1 antagonist | CCR |
AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease. | |||
T77349 | CCR1/5/8 activator 1 | Phospholipase | |
CCR1/5/8 activator 1 is a cytoplasmic phospholipase A inhibitor with antifungal activity. | |||
T10710 | CCR1 antagonist 9 | CCR | |
CCR1 antagonist 9 is an effective and selective CCR1 antagonist (IC50: 6.8 nM in calcium flux assay). | |||
T10709 | CCR1 antagonist 7 | CCR | |
CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1]. | |||
T14899 | CCR1 antagonist 8 | CCR | |
CCR1 antagonist 8, a third azaindazole series compound, is a CCR1 antagonist (IC50: 1.8 nM in Ca2+ flux assay). | |||
T64242 | CCR1 antagonist 11 hydrochloride | ||
CCR1 antagonist 11 hydrochloride (A1B1) is an orally active CCR1 antagonist that acts on hCCR1 (IC50: 0/.03 μM), mCCR1 (IC50: 0.58 μM), rCCR1 (IC50: 0.32 μM). 11 hydrochloride can be used to study rheumatoid arthritis an... | |||
T28072 | MLN-3897 | AVE9897,AVE 9897,CCR1 antagonist 10,AVE-9897 | CCR |
MLN-3897 (CCR1 antagonist 10) is an orally active antagonist of CCR1 with a Ki of 2.3 nM for 125I-MIP-1α binding to THP-1 cell membranes. MLN-3897 inhibits Akt signaling and MM cell survival and proliferation. | |||
T11699 | J-113863 | CCR | |
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-α receptor... | |||
T2375 | BX471 | BX 471,BX-471,ZK-811752 | CCR |
BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist. | |||
T26861 | BMS-817399 | BMS817399 | CCR |
BMS-817399 is an orally active antagonist of CCR1 with IC50s of binding affinity and chemotaxis inhibition potencies and can be used in studies about rheumatoid arthritis. | |||
T28072L | MLN-3897 TFA | MLN-3897 TFA(1010731-97-1 Free base) | CCR |
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes. | |||
T3188 | RE-640 | CCR , Parasite | |
NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities. | |||
TQ0283 | RS102895 | CCR | |
RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1. | |||
T5384 | RS 504393 | CCR | |
RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1). | |||
T14845 | BX471 hydrochloride | ZK-811752 hydrochloride | Others |
BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4. | |||
T23492 | UCB 35625 | Others | |
chemokine CCR1 and CCR3 receptor antagonist | |||
T31061 | CP-481715 | CP 481,715,CP-481,715,CP481715,CP481,715 | |
CP 481715 is an effective selective CCR1 antagonist with potential therapeutic significance for inflammatory diseases. | |||
T26849 | BMS-457 | ||
BMS-457 is a potent, CCR1-selective antagonist. | |||
T71905 | BX-513 HCl | ||
BX-513 HCl is a selective CCR1 receptor antagonist. | |||
T73371 | BAY-3153 | ||
BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) . | |||
T68427 | MLN-3897 citrate | ||
MLN-3897 citrate is a C-C Motif Chemokine Receptor 1 (CCR1) antagonist potentially for the treatment of multiple sclerosis and rheumatoid arthritis. | |||
T41016 | Vercirnon sodium | GSK-1605786 sodium,CCX282-Bsodium,Traficet-ENsodium | |
Vercirnon (GSK1605786A) sodium is an orally bioavailable, selective, and potent CCR9 antagonist. It effectively inhibits CCR9-mediated calcium mobilization and chemotaxis in Molt-4 cells, exhibiting IC50 values of 5.4 nM... | |||
T12773 | RS102895 hydrochloride | Others , 5-HT Receptor , CCR | |
RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM). | |||
T17274 | YM022 | CCR | |
YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist. YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo. YM022 shows the Ki v... |
Cat No. | Product Name | Species | Expression System |
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TMPJ-00005 | CCL3 Protein, Human, Recombinant | Human | E. coli |
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits che... | |||
TMPJ-00591 | CCL8 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemo... | |||
TMPY-03779 | CCL27 Protein, Human, Recombinant (His) | Human | E. coli |
CCL27, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27 is chemotactic for skin-associated memory T lymphoc... | |||
TMPJ-00010 | CCL8 Protein, Human, Recombinant | Human | E. coli |
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemo... | |||
TMPY-00641 | LEC/CCL16 Protein, Human, Recombinant (His) | Human | E. coli |
CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is ... | |||
TMPJ-00018 | CCL16 Protein, Human, Recombinant | Human | E. coli |
CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC c... | |||
TMPJ-01000 | CCL9 Protein, Mouse, Recombinant | Mouse | E. coli |
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some express... | |||
TMPY-02468 | CCL14 Protein, Human, Recombinant (aa 28-93, His) | Human | E. coli |
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is... | |||
TMPJ-00993 | CCL5 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
C-C motif chemokine 5(CCL5) is a β-chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. CCL5 is secreted by many cell types at inflammatory s... | |||
TMPY-02257 | CCL14 Protein, Human, Recombinant (His) | Human | E. coli |
CCL14 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14, is a human CC chemokine that is... | |||
TMPJ-00873 | CCL3L1 Protein, Human, Recombinant (His) | Human | Human Cells |
C-C Motif Chemokine 3-Like 1 (CCL3L1) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL3L1 is a ligand for CCR1, CCR3 and CCR5. CCL3L1 binds to several chemokine receptors including che... | |||
TMPJ-00831 | CCL3 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
C-C Motif Chemokine 3 (MIP-1 alpha,CCL3 ) is a member of the beta or CC subfamily of chemokines and is closely related to CCL4/MIP-1 beta. CCL3 expression can be induced in a variety of hematopoietic cells, fibroblasts, ... | |||
TMPY-00564 | MCP-4 Protein, Human, Recombinant (His) | Human | Yeast |
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family ... | |||
TMPY-02075 | MIP-5 Protein, Human, Recombinant (aa 22-113, His) | Human | E. coli |
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location... | |||
TMPY-02688 | MIP-5 Protein, Human, Recombinant (aa 46-113, His) | Human | E. coli |
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location... | |||
TMPY-02104 | MCP-2 Protein, Mouse, Recombinant (His & NusA) | Mouse | E. coli |
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location... | |||
TMPY-01887 | MCP-2 Protein, Human, Recombinant (SUMO) | Human | E. coli |
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location... | |||
TMPY-04680 | MCP-2 Protein, Human, Recombinant (His) | Human | Yeast |
Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved location... |
Cat No. | Product Name | ||
---|---|---|---|
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |