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Cat No. | Product Name | Synonyms | Targets |
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T64338 | AKI603 | AKI 603,AKI-603 | Aurora Kinase |
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l... | |||
T68332 | AKI-001 | ||
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Phenotypic cellular... | |||
T37596 | Terevalefim | c-Met/HGFR | |
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor. | |||
T1439 | Lacidipine | SN-305,GX-1048,GR-43659X | Apoptosis , Calcium Channel , Reactive Oxygen Species |
Lacidipine (SN-305) is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia. It displays specifi... | |||
T76784 | Tildrakizumab | MK 3222,SCH 900222 | IL Receptor |
Tildrakizumab (SCH 900222) is a potent humanized monoclonal antibody against IL-23 (p19 subunit). Tildrakizumab targets single-stranded IL-23 with a Kd value of 136 pM. Tildrakizumab can be used to study psoriasis and ps... | |||
T28950 | Terlakiren | CP 80794,CP-80,794 | RAAS |
Terlakiren (CP-80,794) is an orally active and potent renin inhibitor that inhibits the potency of human renin for the study of neurological disorders of the hypertension class. | |||
TP2075L | Bombinakinin M acetate | Bombinakinin M acetate(509151-65-9 free base) | Bradykinin Receptor |
Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin. | |||
T73695 | Canakinumab | ACZ 885,Ilaris | IL Receptor |
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody.Canakinumab has been shown to inhibit human and chorioallantoic monkey IL-1β, with IC50 values of 43.6 and 40.8 pM, respectively.Canakinumab... | |||
T76775 | Fezakinumab | ILV 094 | Interleukin |
Fezakinumab is a potent monoclonal antibody to interleukin-22 (IL-22). Fezakinumab can be used to study immune system diseases and inflammation-related conditions such as psoriasis, rheumatoid arthritis and atopic dermat... | |||
T8813 | Tetrakis (4-carboxyphenyl) porphyrin | TCPP,Tetracarboxyphenylporphine | Others |
Tetrakis (4-carboxyphenyl) porphyrin (TCPP) plays the role of a metal remover.Tetrakis (4-carboxyphenyl) porphyrin is a fabricated three dimensional Ru polymer complex. It can be grafted on SiO2/Nb2O5 substrate and subse... | |||
T4264 | Takinib | EDHS-206 | Apoptosis , MAPK |
Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM). | |||
T66574 | Sodium tetrakis (pentafluorophenyl)-borate | ||
sodium tetrakis (pentafluorophenyl)-borate is a useful organic compound for research related to life sciences and the catalog number is T66574. | |||
T77034 | Inbakicept | N-803 | |
Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity (ADCC). ... | |||
T82882 | Binetrakin | ||
Binetrakin (Interleukin 4 (human)) is a pleiotropic cytokine derived from T lymphocytes that influences multiple cell types, such as B cells and T cells, and promotes the differentiation of naive helper T cells (Th0 cell... | |||
TP2225 | Bombinakinin-GAP | Others | |
Bioactive bradykinin-related peptide | |||
T75711 | Contulakin G | ||
Contulakin G, an O-glycosylated invertebrate neurotensin, serves as a weaker agonist for the neurotensin receptor. Additionally, it is recognized as a potent antinociceptive agent [1] [2]. | |||
T67239 | Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) | ||
Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) is a useful organic compound for research related to life sciences. The catalog number is T67239 and the CAS number is 909389-99-7. | |||
T80607 | Eblasakimab | CSL-334,ASLAN004 | |
Eblasakimab (also known as ASLAN004 or CSL-334) is a human IgG4 monoclonal antibody that selectively binds to IL13RA1, and is predominantly produced in CHO-K1 cells [1]. | |||
T32840 | Locustakinin | Ala-phe-ser-ser-trp-gly-NH2,Lomk peptide,Locustakinn | |
Locustakinin is a myotropic peptide. | |||
T32358 | Karakin | Carakin,NSC279515,Karakine,NSC-279515,NSC 279515 | |
Karakin is a group of plant growth regulators. | |||
T64631 | 2,4,5,6-Tetrakis(diphenylamino)isophthalonitrile | ||
2,4,5,6-Tetrakis(diphenylamino)isophthalonitrile is a useful organic compound for research related to life sciences and the catalog number is T64631. | |||
T65464 | 4,4′,4″,4″′-(Porphine-5,10,15,20-tetrayl)tetrakis(benzenesulfonic acid) | ||
4,4′,4″,4″′-(Porphine-5,10,15,20-tetrayl)tetrakis(benzenesulfonic acid) is a useful organic compound for research related to life sciences and the catalog number is T65464. | |||
T76823 | Perakizumab | ||
Perakizumab (RG4934), a humanized IgG1κ monoclonal antibody targeting IL-17A (Interleukin Related), is utilized in the study of autoimmune conditions, including psoriatic arthritis [1]. | |||
T76840 | Vunakizumab | ||
Vunakizumab (Anti-Human IL17A Recombinant Antibody), a recombinant human IgGκ monoclonal antibody, specifically targets and inhibits IL-17A's interaction with its receptor, making it useful for researching autoimmune con... | |||
T73743 | 1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol] | ||
1,1′,1′′,1′′′-[1,4-Piperazinediylbis(2,1-ethanediylnitrilo)]tetrakis[2-dodecanol], a lipid/lipidoid, is utilized in the synthesis of lipid-based or lipidoid nanoparticles [1]. | |||
T76942 | Cendakimab | ||
Cendakimab (RPC4046; ABT 308; CC-93538) is a selective humanized recombinant monoclonal antibody targeting the IL-13 molecule with high specificity. It demonstrates potent affinity for both the wild-type and variant form... | |||
T76972 | Tozorakimab | ||
Tozorakimab (MEDI-3506), a human immunoglobulin G1 monoclonal antibody, targets interleukin-33 and is utilized in researching chronic obstructive pulmonary disease (COPD) [1]. | |||
T77171 | Efineptakin alfa | ||
Efineptakin alfa (NT-17), a long-acting recombinant human interleukin-7 (IL-7), promotes the proliferation and survival of CD4+ and CD8+ cells in both humans and mice. It has applications in glioblastoma research [1]. | |||
T76914 | Avizakimab | ||
Avizakimab (BOS161721), a humanized IgG1 monoclonal antibody, specifically targets interleukin-21 [1]. | |||
T76935 | Briakinumab | ||
Briakinumab (ABT-874), a fully human anti-IL-12/23p40 monoclonal antibody, selectively targets and neutralizes IL-12 and IL-23. This compound is utilized in the research of various autoimmune disorders, including rheumat... | |||
T33396 | Misakimycin | ||
Misakimycin is a mammalian cell growth stimulating substance produced by Streptomyces misakiensis BP-3621. | |||
TNU1667 | 3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine | ||
3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl] cytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1667. | |||
T66647 | Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin | ||
Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is a useful organic compound for research related to life sciences and the catalog number is T66647. | |||
T126551 | Kakisaponin A | ||
Kakisaponin A is a useful organic compound for research related to life sciences. The catalog number is T126551 and the CAS number is 1003864-78-5. | |||
T70781 | Ranakinin | ||
Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda. | |||
T77098 | Netakimab | ||
Netakimab, an anti-IL-17 monoclonal antibody, is utilized in the research of ankylosing spondylitis, psoriatic arthritis, and moderate-to-severe plaque psoriasis [1] [2]. | |||
T81509 | Perisulfakinin | ||
Perisulfakinin, a satiety-signaling neuropeptide, suppresses the activity of neurons that stimulate general activity [1]. | |||
T76675 | Clazakizumab | ||
Clazakizumab, a monoclonal antibody, demonstrates high affinity and specificity towards the interleukin-6 (IL-6) cytokine, potentially inhibiting the cytokine response in COVID-19 caused by SARS-CoV-2. It is also under r... | |||
TP2075 | Bombinakinin M | ||
Potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth m... | |||
T80730 | Zigakibart | BION-1301 | |
Zigakibart (BION-1301) is a humanized monoclonal antibody of the IgG4-kappa subtype, targeting TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, APRIL, CD256), and exhibits anti-inflammatory activity [1]. | |||
T80559 | Duvakitug | ||
Duvakitug, a humanized IgG1-λ2 monoclonal antibody, targets TNFSF15/TL1A and is primarily expressed in CHOK1SV cells with endogenous glutamine synthetase (GS) activity. It has applications in the research of Crohn's Dise... | |||
TNU0901 | 4-Amino-1-[3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one | ||
4-Amino-1-[3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one is a nucleoside derivative. | |||
T76251L | Ac-FEID-CMK TFA | Pyroptosis | |
Ac-FEID-CMK TFA is a selective zebrafish GSDMEb-derived peptide inhibitor that reduces mortality and renal injury in infectious shock.Ac-FEID-CMK TFA inhibits pyroptosis in vivo, attenuates septic AKI (acute kidney injur... | |||
T76251 | Ac-FEID-CMK | ||
Ac-FEID-CMK, a potent peptide inhibitor derived from zebrafish-specific GSDMEb, effectively reduces mortality and kidney injury during septic shock by inhibiting pyroptosis and mitigating acute kidney injury (AKI) in viv... | |||
T33678 | NIR-O2˙– | NIR O2˙–,NIRO2˙– | |
NIR-O2˙– is a NIR NIR O2˙– probe which displays superior sensitivity to NIR O2˙– and has the capability to monitor trace amounts of intracellular NIR O2˙– in AKI in vivo. | |||
T78802 | SIRT5 inhibitor 6 | Sirtuin | |
SIRT5 Inhibitor 6 is a potent, selective, and substrate-competitive inhibitor of SIRT5, exhibiting an IC50 of 3.0 μM, and demonstrates therapeutic potential for treating septic acute kidney injury (AKI) in vivo [1]. | |||
T81177 | Ser@TPP@CUR | ||
Ser nM TPP nM CUR, a derivative of Curcumin, notably mitigates damage in renal tubular epithelial cells and enhances renal function in mice with acute kidney injury (AKI). This compound holds potential for AKI research a... | |||
T38616 | Teprasiran | QPI-1002 | |
Teprasiran (QPI-1002) is an RNA-based compound that transiently suppresses p53-dependent apoptosis, a process involved in the development of acute kidney injury (AKI). | |||
T75268 | 84-B10 | ||
84-B10, a derivative of 3-phenylglutaric acid, inhibits cisplatin-induced tubular ferroptosis, attenuates mitochondrial damage and oxidative stress, and ameliorates acute kidney injury (AKI) resulting from cisplatin admi... | |||
T62298 | PHD2/HDACs-IN-1 | ||
PHD2/HDACs-IN-1 is a potent mixed inhibitor of PHD2/HDACs, acting on PHD2 (IC50: 1.15 μM), HDAC1 (IC50: 19.75 μM), HDAC2 (IC50: 26.60 μM), HDAC16 (IC50: 15.98 μM). HDACs-IN-1 is a low toxicity nephroprotective agent that... |
Cat No. | Product Name | Synonyms | Targets |
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T2870 | Matrine | Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine | Mitophagy , Ferroptosis , Opioid Receptor , Autophagy |
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. | |||
TQ0264 | Nigakinone | Others | |
Nigakinone, isolated from Kumu, is an alkaloid with the pharmacological activity. | |||
TN2051 | Perakine | Others | |
Perakine is a natural product of Rauvolfia, Apocynaceae. The catalog number is TN2051 and the CAS number is 4382-56-3. Perakine can be used as a reference standard. | |||
T79944 | 2-O-Sinapoyl makisterone A | COX | |
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively suppressing the expression of COX-2 protein [1]. | |||
TN5298 | Makisterone A 20,22-monoacetonide | ||
Makisterone A 20,22-monoacetonide is a natural product for research related to life sciences. The catalog number is TN5298 and the CAS number is 245323-24-4. | |||
T37471 | Makisterone A | ||
Makisterone A is an ecdysteroid that drives molting in insects. It binds the heterodimeric ecdysone receptor with nanomolar affinity. | |||
T11712 | Jasplakinolide | Jaspamide,NSC-613009 | Microtubule Associated , Antifungal |
Jasplakinolide(Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin... | |||
T81153 | Sitakisogenin | ||
Sure, please provide the description of the chemical compound you'd like to be rewritten. | |||
T8181 | Poricoic acid A | Poricoic acid A(F) | Others |
Poricoic acid A (Poricoic acid A(F)) is a natural product with antitumor activity. It also enhances melatonin inhibition of AKI-to-CKD transition by regulating the Gas6/AxlNFκB/Nrf2 axis. |
Cat No. | Product Name | Species | Expression System |
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TMPY-05898 | Influenza A H3N2 (A/swine/Miyazaki/2/2013) Hemagglutinin/HA Protein (His) | H3N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPY-05878 | Influenza A H1N2 (A/swine/Miyazaki/1/2006) Hemagglutinin/HA Protein (His) | H1N2 | HEK293 |
The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two... | |||
TMPH-03701 | Vespakinin-M Protein, Vespa mandarinia, Recombinant (His & KSI) | Vespa mandarinia | E. coli |
Vespakinin-M Protein, Vespa mandarinia, Recombinant (His & KSI) is expressed in E. coli. | |||
TMPH-03076 | Astakine Protein, Pacifastacus leniusculus, Recombinant (His & Myc) | Pacifastacus leniusculus | E. coli |
Cytokine directly involved in hematopoiesis. | |||
TMPH-00059 | Major allergen Ani s 1 Protein, Anisakis simplex, Recombinant (His & Myc) | Anisakis simplex | E. coli |
TMPY-00873 | Lipocalin-2/LCN2 Protein, Human, Recombinant (His) | Human | HEK293 |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... | |||
TMPY-00988 | Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... | |||
TMPK-00085 | NGAL/Lipocalin-2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Acute kidney injury (AKI) is one of the most common complications of various serious conditions, and early diagnosis is therefore critical for the treatment of AKI. Recent evidence demonstrates that neutrophil gelatinase... | |||
TMPK-01289 | NGAL/Lipocalin-2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Acute kidney injury (AKI) is one of the most common complications of various serious conditions, and early diagnosis is therefore critical for the treatment of AKI. Recent evidence demonstrates that neutrophil gelatinase... | |||
TMPY-01737 | Meprin alpha/MEP1A Protein, Human, Recombinant (His) | Human | HEK293 |
Meprin A subunit alpha, also known as MEP1A, and Endopeptidase-2, is a single-pass type I membrane protein that belongs to the peptidase M12A family. MEP1A contains one EGF-like domain, one MAM domain, and one MATH domai... | |||
TMPY-01318 | Meprin alpha/MEP1A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Meprin A subunit alpha, also known as MEP1A, and Endopeptidase-2, is a single-pass type I membrane protein that belongs to the peptidase M12A family. MEP1A contains one EGF-like domain, one MAM domain, and one MATH domai... | |||
TMPY-05203 | Lipocalin-2/LCN2 Protein, Mouse, Recombinant | Mouse | HEK293 |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... | |||
TMPY-02316 | Lipocalin-2/LCN2 Protein, Rat, Recombinant (His) | Rat | Baculovirus-Insect Cells |
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,... |