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Search Results for " ?anticonvulsant "

Targets

178

Compounds

30

Natural Products

Cat No. Product Name Synonyms Targets
T73586 Anticonvulsant agent 2 Others
Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy.
T3563 Lvguidingan Others
Lvguidingan is an Anticonvulsant agent.
T10027 Anticonvulsant agent 1 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide Others
Anticonvulsant agent 1 is an anticonvulsant compound.
T8588 Buramate Antibacterial
Buramate is an antipsychotic and anticonvulsant.
T15545 ICA-27243 Potassium Channel
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects.
T0413 Cinromide trans-3-Bromo-N-ethylcinnamamide Others
Cinromide (trans-3-Bromo-N-ethylcinnamamide) is used as a novel anticonvulsant agent.
T6259 Dizocilpine MK-801 NMDAR , iGluR
MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM.
T0600 10,11-Dihydrocarbamazepine Dihydrocarbamazepine Others
10,11-Dihydrocarbamazepine (Dihydrocarbamazepine) is used as pharmaceutical intermediates.
T22675 Co 102862 V 102862 Others , Sodium Channel
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
T0440 Oxcarbazepine GP 47680 Apoptosis , Sodium Channel
Oxcarbazepine (GP 47680) is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activity.
T0283 Trimethadione 3,5,5,-Trimethyloxazolidine-2,4-dione Calcium Channel
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.
TP2036L DPDPE TFA (88373-73-3 free base) DPDPE TFA Opioid Receptor
DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
T7780 Blarcamesine AE-37,AVex-73 AChR
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.
T4118 SB 271046 hydrochloride SB 271046A 5-HT Receptor
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ...
T0992 Carbenoxolone disodium Biogastrone,Duogastrone,Bioral Gap Junction Protein
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ...
TP2036 DPDPE Opioid Receptor
DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.
T14983 Clomethiazole Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE P450 , GABA Receptor
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C...
T2535 Ivabradine hydrochloride S 16257-2,Ivabradine HCl Adrenergic Receptor
Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat...
T21029 Norfluoxetine Hydrochloride Norfluoxetine HCl Others
Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug.
T7806 Licarbazepine ​10,11-hydroxy-10,11 Dihydrocarbamezer Others
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.
T1602 Valproic acid sodium salt Sodium Valproate Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha...
T8456 GALNON Neuropeptide Y Receptor
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
T6474 Divalproex Sodium Valproate semisodium,Epival HDAC
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...
T8435 YM90K YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- GluR , iGluR
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
T3320 Dizocilpine Maleate (+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate) NMDAR , iGluR
Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of ne...
T6651 Safinamide mesylate PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate MAO , Monoamine Oxidase
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A.
T15302 Fluzinamide AHR-8559 Others
Fluzinamide (AHR-8559) has anticonvulsant effects on ignited amygdala seizures.
T14863 Carabersat SB 204269 Others
Carabersat(SB 204269) is a novel and effective anticonvulsant and antiepileptic agent.
T1249 Beclamide N-Benzyl-3-chloropropionamide,Chloracon,Chlorakon Others
Beclamide (Chlorakon) (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was studied in the 1950s for its a...
T40709 3-Diethylamino-1-propanol Others
3-Diethylamino-1-propanol exhibits anticonvulsant effects.
T28503 Ralitoline GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum
Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity.
T10774 CFM-2 iGluR
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.
T31614 Elpetrigine GW-273293,JZP 4,JZP4,GW273293,JZP-4,GW 273293
Elpetrigine( GW 273293, JZP-4) is effective calcium and sodium channel blocker and is currently being evaluated in patients as an anticonvulsant and mood stabilizer.
T7843 4-phenoxypiperidine Others
4-phenoxypiperidines with muscle relaxant and anticonvulsant activities.
T21425 Mephenytoin Mesantoin,Methoin,Insulton,Phenantoin,Methylphenetoin P450
Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6.
T3562 Valrocemide TV1901,N-Valproylglycinamide Others
Valrocemide (TV1901), also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is an anticonvulsant agent under ...
T11278 FG8119 NNC13-8119 Others
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.
T8604 Fenaclon Fenaclonum Others
Fenaclon (Fenaclonum) is an anticonvulsant. It is indicated for the treatment of epilepsy.
T5517 (R)-Carisbamate Others
(R)-Carisbamate is the R-isomer of Carisbamate . Carisbamate is an experimental anticonvulsant drug.
T14974 Citenamide Cytenamide,AY-15613 Others
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties.
T27288 Esuprone LU-43839,LU 43839,LU43839 MAO
Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression.
T6744 Methylbenactyzium Bromide Noinarin,Paragone,Methylbenactyzine Bromide,Semulgin,Gastrimade AChR
Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.
T36839 (R)-Mephenytoin R-Mephenytoin,(R)-Mephenytoin,(–)-Mephenytoin Others
(R)-Mephenytoin ((–)-Mephenytoin) is the the R-enantiomer of Mephenytoin which is an anticonvulsant agent.
T68054 Denzimol Others
Denzimol is a novel anticonvulsant compound.Denzimol is selective for tonic seizures.
T1234 5,5-Dimethyloxazolidine-2,4-dione Dimethadion,Dimethadione,Dimethyloxazolidinedione Calcium Channel
5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.
T8594 Pheneturide 2-PHENYLBUTYRYLUREA,S-46,Benuride Others
Pheneturide (Benuride) is the ureide class, used to treat epilepsy, and is an anticonvulsant.
T11349 GABAA receptor agent 1 GABA Receptor
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor.
T31354 Decimemide V 285,V-285,V285 Others
Decimemide (V-285) is an alkoxybenzoic acid derivative with antiepileptic activity and potential anticonvulsant activity that can be used to study neurological disorders.
T10796 Chlormethiazole hydrochloride Clomethiazole hydrochloride Others
Chlormethiazole hydrochloride is an anticonvulsant and sedative. It also has neuroprotective.
T23717 Ameltolide Others
Ameltolide is an anticonvulsant agent. It has been shown to be effective at inhibiting seizures in animal models.

Compounds

Anticonvulsant agent 2
T73586
Synonym:
Target: Others
Lvguidingan
T3563
Synonym:
Target: Others
Anticonvulsant agent 1
T10027
Synonym: 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide
Target: Others
Buramate
T8588
Synonym:
Target: Antibacterial
ICA-27243
T15545
Synonym:
Target: Potassium Channel
Cinromide
T0413
Synonym: trans-3-Bromo-N-ethylcinnamamide
Target: Others
Dizocilpine
T6259
Synonym: MK-801
Target: NMDAR, iGluR
10,11-Dihydrocarbamazepine
T0600
Synonym: Dihydrocarbamazepine
Target: Others
Co 102862
T22675
Synonym: V 102862
Target: Others, Sodium Channel
Oxcarbazepine
T0440
Synonym: GP 47680
Target: Apoptosis, Sodium Channel
Trimethadione
T0283
Synonym: 3,5,5,-Trimethyloxazolidine-2,4-dione
Target: Calcium Channel
DPDPE TFA (88373-73-3 free base)
TP2036L
Synonym: DPDPE TFA
Target: Opioid Receptor
Blarcamesine
T7780
Synonym: AE-37,AVex-73
Target: AChR
SB 271046 hydrochloride
T4118
Synonym: SB 271046A
Target: 5-HT Receptor
Carbenoxolone disodium
T0992
Synonym: Biogastrone,Duogastrone,Bioral
Target: Gap Junction Protein
DPDPE
TP2036
Synonym:
Target: Opioid Receptor
Clomethiazole
T14983
Synonym: Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE
Target: P450, GABA Receptor
Ivabradine hydrochloride
T2535
Synonym: S 16257-2,Ivabradine HCl
Target: Adrenergic Receptor
Norfluoxetine Hydrochloride
T21029
Synonym: Norfluoxetine HCl
Target: Others
Licarbazepine
T7806
Synonym: ​10,11-hydroxy-10,11 Dihydrocarbamezer
Target: Others
Valproic acid sodium salt
T1602
Synonym: Sodium Valproate
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, HDAC, Autophagy
GALNON
T8456
Synonym:
Target: Neuropeptide Y Receptor
Divalproex Sodium
T6474
Synonym: Valproate semisodium,Epival
Target: HDAC
YM90K
T8435
Synonym: YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-
Target: GluR, iGluR
Dizocilpine Maleate
T3320
Synonym: (+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate)
Target: NMDAR, iGluR
Safinamide mesylate
T6651
Synonym: PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate
Target: MAO, Monoamine Oxidase
Fluzinamide
T15302
Synonym: AHR-8559
Target: Others
Carabersat
T14863
Synonym: SB 204269
Target: Others
Beclamide
T1249
Synonym: N-Benzyl-3-chloropropionamide,Chloracon,Chlorakon
Target: Others
3-Diethylamino-1-propanol
T40709
Synonym:
Target: Others
Ralitoline
T28503
Synonym: GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum
Target:
CFM-2
T10774
Synonym:
Target: iGluR
Elpetrigine
T31614
Synonym: GW-273293,JZP 4,JZP4,GW273293,JZP-4,GW 273293
Target:
4-phenoxypiperidine
T7843
Synonym:
Target: Others
Mephenytoin
T21425
Synonym: Mesantoin,Methoin,Insulton,Phenantoin,Methylphenetoin
Target: P450
Valrocemide
T3562
Synonym: TV1901,N-Valproylglycinamide
Target: Others
FG8119
T11278
Synonym: NNC13-8119
Target: Others
Fenaclon
T8604
Synonym: Fenaclonum
Target: Others
(R)-Carisbamate
T5517
Synonym:
Target: Others
Citenamide
T14974
Synonym: Cytenamide,AY-15613
Target: Others
Esuprone
T27288
Synonym: LU-43839,LU 43839,LU43839
Target: MAO
Methylbenactyzium Bromide
T6744
Synonym: Noinarin,Paragone,Methylbenactyzine Bromide,Semulgin,Gastrimade
Target: AChR
(R)-Mephenytoin
T36839
Synonym: R-Mephenytoin,(R)-Mephenytoin,(–)-Mephenytoin
Target: Others
Denzimol
T68054
Synonym:
Target: Others
5,5-Dimethyloxazolidine-2,4-dione
T1234
Synonym: Dimethadion,Dimethadione,Dimethyloxazolidinedione
Target: Calcium Channel
Pheneturide
T8594
Synonym: 2-PHENYLBUTYRYLUREA,S-46,Benuride
Target: Others
GABAA receptor agent 1
T11349
Synonym:
Target: GABA Receptor
Decimemide
T31354
Synonym: V 285,V-285,V285
Target: Others
Chlormethiazole hydrochloride
T10796
Synonym: Clomethiazole hydrochloride
Target: Others
Ameltolide
T23717
Synonym:
Target: Others
1 2 3 4
Cat No. Product Name Synonyms Targets
T5563 Cyclohexanecarboxylic Acid Others , Endogenous Metabolite
Cyclohexanecarboxylic acid is a flavouring ingredien
T8014 Epoxylinalool 2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran Others
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) is a naturally occurring monoterpene alcohol widely used in the production of perfumes and flavors.
T3248 Alpha-Boswellic acid α-Boswellic acid Others
alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense and has anticonvulsant and anticancer effects. In animals, it prevents and reduces Alzheimer's disease mar...
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
TN2865 (E)-3,4,5-Trimethoxycinnamic acid O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid Others
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum.
T0361 Isovaleramide 3-Methylbutanamide Dehydrogenase
Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.
T65135 Kynurenic acid Fibrostop 2,Quinurenic acid GPR , GluR , NMDAR
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...
T20587 2-Acetonaphthone beta-Acetylnaphthalene,beta-Acetonaphthalene,2Acetylnaphthalene,2-Acetylnaphthalene,2 Acetylnaphthalene,beta-Naphthyl methyl ketone Endogenous Metabolite
2-Acetonaphthone (beta-Naphthyl methyl ketone) is a fragrance, anticonvulsant, and antimicrobial agent. It has an onion type flavor and a sulfurous type odor.
TN4114 Gardenin A ERK , LDL , MAPK , PKA , PKC
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects.
T5266 Tricaprilin Glycerol Tri-n-octanoate,trioctanoin,tricaprylic glyceride,Glyceryl trioctanoate Others , Endogenous Metabolite
Tricaprilin (Glycerol Tri-n-octanoate) is used in study for patients with mild to moderate Alzheimer's disease. Tricaprilin also has a role as an anticonvulsant and a plant metabolite.
T4842 1H-pyrazole 1,2-Diazole,Pyrazole Others , Endogenous Metabolite
1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythm...
T0728 Ethosuximide Zarontin Calcium Channel
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures.
TN7252 Olivetolic acid 2,4-Dihydroxy-6-pentylbenzoic acid Antibiotic
Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity.
T5758 Sphondin COX , Prostaglandin Receptor
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.
T2S1814 P-Hydroxybenzaldehyde 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde Transaminase , GABA Receptor , Endogenous Metabolite
1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic...
T5566 Ethyl maltol 2-Ethyl-3-hydroxy-4H-pyran-4-one,2-Ethyl pyromeconic acid Others
Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an extract from medicinal plants such as P. Incarnata and can be used as an anticonvulsant. It is also a common flavoring.
TN5131 Tetrahydrocannabivarin THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin Cannabinoid Receptor
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob...
Fr14115 α-Terpineol Terpineol IL Receptor , Anti-infection , Antibacterial
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, ...
TMO2713 4(3H)-Quinazolinone Quinazolin-4-ol,4-Hydroxyquinazoline,4-Quinazolinol,4-Quinazolone,4-Quinazolinone Antibacterial , Platelet aggregation
4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, an...
T5739 Paederosidic acid Apoptosis , BCL
Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GA...
T3836 Eudesmin MAPK , S6 Kinase
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...
TN1712 Gossypin NF-κB , S6 Kinase
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i...
T0883 Tramiprosate Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed Beta Amyloid , GABA Receptor
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...
T6S1653 Albiflorin Alibiflorin Reactive Oxygen Species
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...
T37491 11-Oxo etiocholanolone
11-Ketoetiocholanolone is a metabolite of testosterone's excreted metabolite, etiocholanolone, and exhibits anticonvulsant activity[1][2].
T12373 Paxilline Others
Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity.
T11534 Haemanthamine Others
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiv...
TN4322 Isopulegol ATPase , Potassium Channel , GABA Receptor
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GA...
TN4624 Nantenine Others
Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulati...
T73813 Haemanthamine hydrochloride
Haemanthamine hydrochloride, a crinine-type alkaloid derived from Amaryllidaceae plants, exhibits potent anticancer properties. It acts by targeting ribosomes, thereby inhibiting protein biosynthesis during the translati...

Natural Products

Cyclohexanecarboxylic Acid
T5563
Synonym:
Target: Others, Endogenous Metabolite
Epoxylinalool
T8014
Synonym: 2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran
Target: Others
alpha-Boswellic acid
T3248
Synonym: α-Boswellic acid
Target: Others
Valproic Acid
T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy
(E)-3,4,5-Trimethoxycinnamic acid
TN2865
Synonym: O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid
Target: Others
Isovaleramide
T0361
Synonym: 3-Methylbutanamide
Target: Dehydrogenase
Kynurenic acid
T65135
Synonym: Fibrostop 2,Quinurenic acid
Target: GPR, GluR, NMDAR
2-Acetonaphthone
T20587
Synonym: beta-Acetylnaphthalene,beta-Acetonaphthalene,2Acetylnaphthalene,2-Acetylnaphthalene,2 Acetylnaphthalene,beta-Naphthyl methyl ketone
Target: Endogenous Metabolite
Gardenin A
TN4114
Synonym:
Target: ERK, LDL, MAPK, PKA, PKC
Tricaprilin
T5266
Synonym: Glycerol Tri-n-octanoate,trioctanoin,tricaprylic glyceride,Glyceryl trioctanoate
Target: Others, Endogenous Metabolite
1H-pyrazole
T4842
Synonym: 1,2-Diazole,Pyrazole
Target: Others, Endogenous Metabolite
Ethosuximide
T0728
Synonym: Zarontin
Target: Calcium Channel
Olivetolic acid
TN7252
Synonym: 2,4-Dihydroxy-6-pentylbenzoic acid
Target: Antibiotic
sphondin
T5758
Synonym:
Target: COX, Prostaglandin Receptor
p-Hydroxybenzaldehyde
T2S1814
Synonym: 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde
Target: Transaminase, GABA Receptor, Endogenous Metabolite
Ethyl maltol
T5566
Synonym: 2-Ethyl-3-hydroxy-4H-pyran-4-one,2-Ethyl pyromeconic acid
Target: Others
Tetrahydrocannabivarin
TN5131
Synonym: THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin
Target: Cannabinoid Receptor
α-Terpineol
Fr14115
Synonym: Terpineol
Target: IL Receptor, Anti-infection, Antibacterial
4(3H)-Quinazolinone
TMO2713
Synonym: Quinazolin-4-ol,4-Hydroxyquinazoline,4-Quinazolinol,4-Quinazolone,4-Quinazolinone
Target: Antibacterial, Platelet aggregation
Paederosidic acid
T5739
Synonym:
Target: Apoptosis, BCL
Eudesmin
T3836
Synonym:
Target: MAPK, S6 Kinase
Gossypin
TN1712
Synonym:
Target: NF-κB, S6 Kinase
Tramiprosate
T0883
Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed
Target: Beta Amyloid, GABA Receptor
Albiflorin
T6S1653
Synonym: Alibiflorin
Target: Reactive Oxygen Species
11-Oxo etiocholanolone
T37491
Synonym:
Target:
Paxilline
T12373
Synonym:
Target: Others
Haemanthamine
T11534
Synonym:
Target: Others
Isopulegol
TN4322
Synonym:
Target: ATPase, Potassium Channel, GABA Receptor
Nantenine
TN4624
Synonym:
Target: Others
Haemanthamine hydrochloride
T73813
Synonym:
Target:
TargetMol