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Cat No. | Product Name | Synonyms | Targets |
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T73586 | Anticonvulsant agent 2 | Others | |
Anticonvulsant agent 2 is a potent orally active anticonvulsant that has shown antiepileptic activity in a model of drug-resistant epilepsy. | |||
T3563 | Lvguidingan | Others | |
Lvguidingan is an Anticonvulsant agent. | |||
T10027 | Anticonvulsant agent 1 | 4-(2,2-Difluoroethenyl)-α-ethyl-2-oxo-1-pyrrolidineacetamide | Others |
Anticonvulsant agent 1 is an anticonvulsant compound. | |||
T8588 | Buramate | Antibacterial | |
Buramate is an antipsychotic and anticonvulsant. | |||
T15545 | ICA-27243 | Potassium Channel | |
ICA-27243 is less effective at activating KCNQ4 and KCNQ3/Q5. ICA-27243 is a potent and orally active KCNQ2/Q3 potassium channel opener (EC50: 0.38 μM). ICA-27243 also has antiepileptic and anticonvulsant effects. | |||
T0413 | Cinromide | trans-3-Bromo-N-ethylcinnamamide | Others |
Cinromide (trans-3-Bromo-N-ethylcinnamamide) is used as a novel anticonvulsant agent. | |||
T6259 | Dizocilpine | MK-801 | NMDAR , iGluR |
MK-801 (Dizocilpine (MK-801)) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM. | |||
T0600 | 10,11-Dihydrocarbamazepine | Dihydrocarbamazepine | Others |
10,11-Dihydrocarbamazepine (Dihydrocarbamazepine) is used as pharmaceutical intermediates. | |||
T22675 | Co 102862 | V 102862 | Others , Sodium Channel |
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies. | |||
T0440 | Oxcarbazepine | GP 47680 | Apoptosis , Sodium Channel |
Oxcarbazepine (GP 47680) is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T0283 | Trimethadione | 3,5,5,-Trimethyloxazolidine-2,4-dione | Calcium Channel |
Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity. | |||
TP2036L | DPDPE TFA (88373-73-3 free base) | DPDPE TFA | Opioid Receptor |
DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo. | |||
T7780 | Blarcamesine | AE-37,AVex-73 | AChR |
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease. | |||
T4118 | SB 271046 hydrochloride | SB 271046A | 5-HT Receptor |
SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and ... | |||
T0992 | Carbenoxolone disodium | Biogastrone,Duogastrone,Bioral | Gap Junction Protein |
Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... | |||
TP2036 | DPDPE | Opioid Receptor | |
DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo. | |||
T14983 | Clomethiazole | Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE | P450 , GABA Receptor |
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C... | |||
T2535 | Ivabradine hydrochloride | S 16257-2,Ivabradine HCl | Adrenergic Receptor |
Ivabradine hydrochloride (S 16257-2) is a new If inhibitor (IC50: 2.9 μM). Ivabradine Hydrochloride is the hydrochloride salt form of ivabradine, an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gat... | |||
T21029 | Norfluoxetine Hydrochloride | Norfluoxetine HCl | Others |
Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. | |||
T7806 | Licarbazepine | 10,11-hydroxy-10,11 Dihydrocarbamezer | Others |
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders. | |||
T1602 | Valproic acid sodium salt | Sodium Valproate | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , HDAC , Autophagy |
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mecha... | |||
T8456 | GALNON | Neuropeptide Y Receptor | |
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties | |||
T6474 | Divalproex Sodium | Valproate semisodium,Epival | HDAC |
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme... | |||
T8435 | YM90K | YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- | GluR , iGluR |
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor. | |||
T3320 | Dizocilpine Maleate | (+)-Mk-801 Hydrogen Maleate,MK 801,Dizocilpine hydrogen maleate,(+)-MK 801 maleate,(+)-MK 801 (Maleate) | NMDAR , iGluR |
Dizocilpine Maleate (MK 801) is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of ne... | |||
T6651 | Safinamide mesylate | PNU-151774E,FCE28073,PNU-151774E,NW-1015,EMD 1195686 mesylate | MAO , Monoamine Oxidase |
Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A. | |||
T15302 | Fluzinamide | AHR-8559 | Others |
Fluzinamide (AHR-8559) has anticonvulsant effects on ignited amygdala seizures. | |||
T14863 | Carabersat | SB 204269 | Others |
Carabersat(SB 204269) is a novel and effective anticonvulsant and antiepileptic agent. | |||
T1249 | Beclamide | N-Benzyl-3-chloropropionamide,Chloracon,Chlorakon | Others |
Beclamide (Chlorakon) (N-benzyl-B-chloropropionamide) is a drug that possesses anticonvulsant activity. It is no longer used. It has been used as a sedative and as an anticonvulsant. It was studied in the 1950s for its a... | |||
T40709 | 3-Diethylamino-1-propanol | Others | |
3-Diethylamino-1-propanol exhibits anticonvulsant effects. | |||
T28503 | Ralitoline | GOE-4942,PD-117818,Ralitolina,CI-946,Ralitolinum | |
Ralitoline (Ralitolinum) is an anticonvulsant with anticancer activity and sodium channel blocking activity. | |||
T10774 | CFM-2 | iGluR | |
CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models. | |||
T31614 | Elpetrigine | GW-273293,JZP 4,JZP4,GW273293,JZP-4,GW 273293 | |
Elpetrigine( GW 273293, JZP-4) is effective calcium and sodium channel blocker and is currently being evaluated in patients as an anticonvulsant and mood stabilizer. | |||
T7843 | 4-phenoxypiperidine | Others | |
4-phenoxypiperidines with muscle relaxant and anticonvulsant activities. | |||
T21425 | Mephenytoin | Mesantoin,Methoin,Insulton,Phenantoin,Methylphenetoin | P450 |
Mephenytoin (Phenantoin) is an anticonvulsant and a substrate of CYP2C19 and CYP2B6. | |||
T3562 | Valrocemide | TV1901,N-Valproylglycinamide | Others |
Valrocemide (TV1901), also known as TV-1901, is an antiepileptic drug (AED). Valrocemide has a broad spectrum of anticonvulsant activity and promising potential as a new AED. Valrocemide is an anticonvulsant agent under ... | |||
T11278 | FG8119 | NNC13-8119 | Others |
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders. | |||
T8604 | Fenaclon | Fenaclonum | Others |
Fenaclon (Fenaclonum) is an anticonvulsant. It is indicated for the treatment of epilepsy. | |||
T5517 | (R)-Carisbamate | Others | |
(R)-Carisbamate is the R-isomer of Carisbamate . Carisbamate is an experimental anticonvulsant drug. | |||
T14974 | Citenamide | Cytenamide,AY-15613 | Others |
Citenamide (AY-15613) has anticancer and anticonvulsant activity and is used in the study of neurological disorders because of its sleep-promoting properties. | |||
T27288 | Esuprone | LU-43839,LU 43839,LU43839 | MAO |
Esuprone (LU-43839) is a novel reversible and highly selective MAO-A inhibitor with anticonvulsant activity for the treatment of depression. | |||
T6744 | Methylbenactyzium Bromide | Noinarin,Paragone,Methylbenactyzine Bromide,Semulgin,Gastrimade | AChR |
Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione. | |||
T36839 | (R)-Mephenytoin | R-Mephenytoin,(R)-Mephenytoin,(–)-Mephenytoin | Others |
(R)-Mephenytoin ((–)-Mephenytoin) is the the R-enantiomer of Mephenytoin which is an anticonvulsant agent. | |||
T68054 | Denzimol | Others | |
Denzimol is a novel anticonvulsant compound.Denzimol is selective for tonic seizures. | |||
T1234 | 5,5-Dimethyloxazolidine-2,4-dione | Dimethadion,Dimethadione,Dimethyloxazolidinedione | Calcium Channel |
5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE. | |||
T8594 | Pheneturide | 2-PHENYLBUTYRYLUREA,S-46,Benuride | Others |
Pheneturide (Benuride) is the ureide class, used to treat epilepsy, and is an anticonvulsant. | |||
T11349 | GABAA receptor agent 1 | GABA Receptor | |
GABAA receptor agent 1 has strong anticonvulsant activity and is a high affinity ligand of GABAA receptor. | |||
T31354 | Decimemide | V 285,V-285,V285 | Others |
Decimemide (V-285) is an alkoxybenzoic acid derivative with antiepileptic activity and potential anticonvulsant activity that can be used to study neurological disorders. | |||
T10796 | Chlormethiazole hydrochloride | Clomethiazole hydrochloride | Others |
Chlormethiazole hydrochloride is an anticonvulsant and sedative. It also has neuroprotective. | |||
T23717 | Ameltolide | Others | |
Ameltolide is an anticonvulsant agent. It has been shown to be effective at inhibiting seizures in animal models. |
Cat No. | Product Name | Synonyms | Targets |
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T5563 | Cyclohexanecarboxylic Acid | Others , Endogenous Metabolite | |
Cyclohexanecarboxylic acid is a flavouring ingredien | |||
T8014 | Epoxylinalool | 2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran | Others |
Epoxylinalool (2-(2-Hydroxy-2-Propyl)-5-Methyl-5-Vinyltetrahydrofuran) is a naturally occurring monoterpene alcohol widely used in the production of perfumes and flavors. | |||
T3248 | Alpha-Boswellic acid | α-Boswellic acid | Others |
alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense and has anticonvulsant and anticancer effects. In animals, it prevents and reduces Alzheimer's disease mar... | |||
T7064 | Valproic Acid | Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid | Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy |
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research. | |||
TN2865 | (E)-3,4,5-Trimethoxycinnamic acid | O-Methylsinapic acid,3,4,5-Trimethoxy-trans-cinnamic acid,3,4,5-Trimethoxyphenylacrylic acid | Others |
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural product from the roots and rhizomes of Notopterygium incisum. | |||
T0361 | Isovaleramide | 3-Methylbutanamide | Dehydrogenase |
Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases. | |||
T65135 | Kynurenic acid | Fibrostop 2,Quinurenic acid | GPR , GluR , NMDAR |
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv... | |||
T20587 | 2-Acetonaphthone | beta-Acetylnaphthalene,beta-Acetonaphthalene,2Acetylnaphthalene,2-Acetylnaphthalene,2 Acetylnaphthalene,beta-Naphthyl methyl ketone | Endogenous Metabolite |
2-Acetonaphthone (beta-Naphthyl methyl ketone) is a fragrance, anticonvulsant, and antimicrobial agent. It has an onion type flavor and a sulfurous type odor. | |||
TN4114 | Gardenin A | ERK , LDL , MAPK , PKA , PKC | |
Gardenin A shows neurotrophic effects via activating MAPK/ERK, PKC, and PKA. Gardenin A exhibits antidepressant, anticonvulsant and anxiolytic effects. | |||
T5266 | Tricaprilin | Glycerol Tri-n-octanoate,trioctanoin,tricaprylic glyceride,Glyceryl trioctanoate | Others , Endogenous Metabolite |
Tricaprilin (Glycerol Tri-n-octanoate) is used in study for patients with mild to moderate Alzheimer's disease. Tricaprilin also has a role as an anticonvulsant and a plant metabolite. | |||
T4842 | 1H-pyrazole | 1,2-Diazole,Pyrazole | Others , Endogenous Metabolite |
1H-pyrazole (1,2-Diazole), is a versatile building block, with a vast applications in organic synthesis. The derivatives of Pyrazole are used in medicine, for their analgesic, anti-inflammatory, antipyretic, antiarrhythm... | |||
T0728 | Ethosuximide | Zarontin | Calcium Channel |
Ethosuximide (Zarontin) is an anticonvulsant, blocks the low voltage-activated T-type calcium channel used in the treatment of absence seizures unaccompanied by other types of seizures. | |||
TN7252 | Olivetolic acid | 2,4-Dihydroxy-6-pentylbenzoic acid | Antibiotic |
Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity. | |||
T5758 | Sphondin | COX , Prostaglandin Receptor | |
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells. | |||
T2S1814 | P-Hydroxybenzaldehyde | 4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde | Transaminase , GABA Receptor , Endogenous Metabolite |
1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic... | |||
T5566 | Ethyl maltol | 2-Ethyl-3-hydroxy-4H-pyran-4-one,2-Ethyl pyromeconic acid | Others |
Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an extract from medicinal plants such as P. Incarnata and can be used as an anticonvulsant. It is also a common flavoring. | |||
TN5131 | Tetrahydrocannabivarin | THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin | Cannabinoid Receptor |
Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob... | |||
Fr14115 | α-Terpineol | Terpineol | IL Receptor , Anti-infection , Antibacterial |
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, ... | |||
TMO2713 | 4(3H)-Quinazolinone | Quinazolin-4-ol,4-Hydroxyquinazoline,4-Quinazolinol,4-Quinazolone,4-Quinazolinone | Antibacterial , Platelet aggregation |
4(3H)-Quinazolinone (4-Hydroxyquinazoline) is a chemically synthesized masonry block, a biologically active nitrogen heterocyclic compound. It possesses various biological properties such as antibacterial, antifungal, an... | |||
T5739 | Paederosidic acid | Apoptosis , BCL | |
Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutamic acid in the brain, and it up-regulates expressions of GA... | |||
T3836 | Eudesmin | MAPK , S6 Kinase | |
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m... | |||
TN1712 | Gossypin | NF-κB , S6 Kinase | |
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i... | |||
T0883 | Tramiprosate | Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed | Beta Amyloid , GABA Receptor |
Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB... | |||
T6S1653 | Albiflorin | Alibiflorin | Reactive Oxygen Species |
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ... | |||
T37491 | 11-Oxo etiocholanolone | ||
11-Ketoetiocholanolone is a metabolite of testosterone's excreted metabolite, etiocholanolone, and exhibits anticonvulsant activity[1][2]. | |||
T12373 | Paxilline | Others | |
Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity. | |||
T11534 | Haemanthamine | Others | |
Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiv... | |||
TN4322 | Isopulegol | ATPase , Potassium Channel , GABA Receptor | |
Isopulegol presents depressant- and anxiolytic-like effects, it also has anticonvulsant and bioprotective effects against PTZ-induced convulsions are possibly related to positive modulation of benzodiazepine-sensitive GA... | |||
TN4624 | Nantenine | Others | |
Nantenine is an acetylcholinesterase inhibitor, it functions as an effective antagonist against a wide range of MDMA-induced effects in mice. Nantenine has anticonvulsant effect, which seems attributable to its stimulati... | |||
T73813 | Haemanthamine hydrochloride | ||
Haemanthamine hydrochloride, a crinine-type alkaloid derived from Amaryllidaceae plants, exhibits potent anticancer properties. It acts by targeting ribosomes, thereby inhibiting protein biosynthesis during the translati... |