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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T14303 | Alrizomadlin | APG-115,AA-115 | Mdm2 |
Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-d... |