2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1844 | KPT330,(E)- | (E)-RN,KPT-330,KPT330,KPT 330 | Others , CRM1 |
(E)-RN (KPT 330) is a CRM1-selective inhibitor of nuclear export. It inhibits protein trafficking from the nucleus and induces cell cycle arrest and apoptosis in mesothelioma cells. | |||
T6106 | Selinexor (KPT-330) | Selinexor,KPT-330 | CRM1 |
Selinexor (KPT-330) is a small molecule inhibitor of CRM1 with selective and oral activity. Selinexor blocks the cell cycle, induces apoptosis, and has antitumor activity for the treatment of multiple myeloma. |